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Platelets, ISSN 0953-7104, 05/2017, Volume 28, Issue 4, pp. 333 - 341
A disintegrin and metalloprotease (ADAM) 10 and ADAM17 are ubiquitous transmembrane "molecular scissors" which proteolytically cleave, or shed, the... 
ADAM10 | platelet | ADAM17 | iRhom | TspanC8 | tetraspanin | CYTOPLASMIC DOMAIN | PLATELET TETRASPANIN | ADHERENT LEUKOCYTES | SURFACE EXPRESSION | ALPHA-CONVERTING-ENZYME | TSPANC8 TETRASPANINS | CELL BIOLOGY | ECTODOMAIN CLEAVAGE | EXUDATIVE VITREORETINOPATHY | TNF-ALPHA | HEMATOLOGY | CELL-CELL ADHESION | Special Review Section | Review | Platelet Receptor Shedding
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 02/2016, Volume 291, Issue 7, pp. 3145 - 3157
A disintegrin and metalloprotease 10 (ADAM10) is a ubiquitously expressed transmembrane metalloprotease that cleaves the extracellular regions from its... 
ACTIVATION | ANGIOGENESIS | endothelial cell | INTEGRIN | BIOCHEMISTRY & MOLECULAR BIOLOGY | COMPLEXES | CELL-SURFACE | shedding | cell surface enzyme | ADAM | ADHESION | MICRODOMAINS | TspanC8 | N-cadherin | tetraspanin | platelet | COMPONENT | metalloprotease | GPVI | DOMAINS | EXPRESSION | Endothelium, Vascular - cytology | Amyloid Precursor Protein Secretases - genetics | Human Umbilical Vein Endothelial Cells - metabolism | Humans | Tetraspanins - chemistry | Substrate Specificity | Recombinant Fusion Proteins - metabolism | Blood Platelets - cytology | Proteolysis | Human Umbilical Vein Endothelial Cells - cytology | Surface Properties | Cell Membrane - metabolism | Membrane Proteins - metabolism | Protein Interaction Domains and Motifs | Tetraspanins - genetics | Tetraspanins - metabolism | Peptide Fragments - genetics | Tetraspanin-29 - chemistry | Cell Line | Peptide Fragments - metabolism | ADAM Proteins - chemistry | Membrane Proteins - genetics | Cells, Cultured | ADAM10 Protein | Recombinant Fusion Proteins - chemistry | Amyloid Precursor Protein Secretases - chemistry | Protein Transport | Cell Membrane - enzymology | ADAM Proteins - metabolism | Amyloid Precursor Protein Secretases - metabolism | Peptide Fragments - chemistry | Animals | Membrane Proteins - chemistry | Blood Platelets - metabolism | Endothelium, Vascular - metabolism | Mice | Protein Processing, Post-Translational | Enzyme Activation | ADAM Proteins - genetics | Tetraspanin-29 - metabolism | Tetraspanin-29 - genetics | Cell Biology
Journal Article
JOURNAL OF IMMUNOLOGY, ISSN 0022-1767, 07/2017, Volume 199, Issue 2, pp. 666 - 676
The recruitment of blood leukocytes across the endothelium to sites of tissue infection is central to inflammation, but also promotes chronic inflammatory... 
ADHESION | LEUKOCYTE TRANSMIGRATION | PERMEABILITY | DISINTEGRIN | TRANSENDOTHELIAL MIGRATION | ENDOTHELIAL-CELLS | NOTCH ACTIVATION | IMMUNOLOGY | IDENTIFICATION | VASCULAR ENDOTHELIUM | METALLOPROTEASE 10 ADAM10 | Amyloid Precursor Protein Secretases - genetics | Amyloid Precursor Protein Secretases - immunology | T-Lymphocytes - physiology | Tetraspanins - immunology | Chemokines, CXC - immunology | Cadherins - metabolism | ADAM10 Protein - deficiency | ADAM10 Protein - genetics | Humans | ADAM10 Protein - metabolism | Antigens, CD - genetics | Antigens, CD - metabolism | Membrane Proteins - deficiency | Transendothelial and Transepithelial Migration | Membrane Proteins - metabolism | Cadherins - genetics | Tetraspanins - genetics | Tetraspanins - metabolism | Endothelial Cells - physiology | Chemokine CXCL16 | Membrane Proteins - genetics | Cells, Cultured | Neutrophils - immunology | Neutrophils - physiology | B-Lymphocytes - physiology | Chemokine CX3CL1 - genetics | Membrane Proteins - immunology | Inflammation - immunology | ADAM10 Protein - immunology | Chemokines, CXC - genetics | Endothelial Cells - immunology | Receptors, Scavenger - immunology | Amyloid Precursor Protein Secretases - metabolism | B-Lymphocytes - immunology | Receptors, Scavenger - genetics | Amyloid Precursor Protein Secretases - deficiency | Chemokine CX3CL1 - immunology | T-Lymphocytes - immunology | Cutting tools | Leukocyte migration | Neutrophils | Chronic infection | Lymphocytes T | Leukocytes (neutrophilic) | Leukocytes | Cadherin | Blood | Substrates | Inflammatory diseases | Endothelium | Recruitment | White blood cells | Receptors | Lymphocytes B | Lymphocytes | CXCL16 protein | Peripheral blood | Receptor mechanisms | Cell migration | Chemokines | Innate Immunity and Inflammation
Journal Article
Methods in molecular biology (Clifton, N.J.), 2017, Volume 1591, p. 155
Journal Article
HAEMATOLOGICA, ISSN 0390-6078, 08/2019, Volume 104, Issue 9, pp. 1892 - 1905
Ca2+ entry via Orai1 store-operated Ca2+ channels in the plasma membrane is critical to cell function, and Orai1 loss causes severe immunodeficiency and... 
ACTIVATION | VWF | PORE | DEEP-VEIN THROMBOSIS | TETRASPANIN | ADAM10 | PLATELET-ADHESION | HEMATOLOGY | MYOCARDIAL ISCHEMIA/REPERFUSION INJURY | HEMOSTASIS | CRAC CHANNEL | Index Medicus
Journal Article
2016
The passage of leukocytes across blood vessel walls plays a key role in the immune response to infection in inflammatory conditions. ADAM10 is a ubiquitously... 
QR180 Immunology | RC Internal medicine
Dissertation
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