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Accounts of Chemical Research, ISSN 0001-4842, 03/2015, Volume 48, Issue 3, pp. 722 - 730
Journal Article
2006, ISBN 9783527310951, xviii, 368
Edited by one of the leading experts in the field, this book fills the need for a book presenting the most important methods for high-throughput screenings and... 
Enzymes | Analysis | Life Sciences | Science | Biochemistry
Book
05/2006, ISBN 3527607846
Annotation Edited by one of the leading experts in the field, this book fills the need for a book presenting the most important methods for high-throughput... 
Enzymes | Science
Web Resource
Bioconjugate Chemistry, ISSN 1043-1802, 08/2019, Volume 30, Issue 8, p. 2165
Transfecting nucleic acids into cells is an essential procedure in biological research usually performed using nonviral transfection reagents. Unfortunately,... 
Peptides | Acidification | siRNA | Nucleic acids | pH effects | Cytosol | Nanoparticles | Stereoselectivity | Endocytosis | Dendrimers | Transfection | Reagents | Cell lines | Protonation | Peptide synthesis | Solid phases | Conformation | Index Medicus
Journal Article
Journal of the American Chemical Society, ISSN 0002-7863, 07/2009, Volume 131, Issue 25, pp. 8732 - 8733
Journal Article
Accounts of Chemical Research, ISSN 0001-4842, 12/2006, Volume 39, Issue 12, pp. 925 - 934
Journal Article
Journal of cheminformatics, ISSN 1758-2946, 2017, Volume 9, p. 11
Several web-based tools have been reported recently which predict the possible targets of a small molecule by similarity to compounds of known bioactivity... 
Journal Article
Journal of Chemical Information and Modeling, ISSN 1549-9596, 02/2013, Volume 53, Issue 2, pp. 509 - 518
The MQN-mapplet is a Java application giving access to the structure of small molecules in large databases via color-coded maps of their chemical space. These... 
Databases, Pharmaceutical | Models, Molecular | Small Molecule Libraries - chemistry | Ligands | Software | Databases, Chemical | Index Medicus
Journal Article
Bioinformatics, ISSN 1367-4803, 04/2018, Volume 34, Issue 8, pp. 1433 - 1435
Abstract Motivation During the past decade, big data have become a major tool in scientific endeavors. Although statistical methods and algorithms are... 
DATABASE | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | BIOCHEMICAL RESEARCH METHODS | MATHEMATICAL & COMPUTATIONAL BIOLOGY | Index Medicus
Journal Article
Molecular Informatics, ISSN 1868-1743, 05/2019, Volume 38, Issue 5, pp. 1980501 - n/a
The cover picture shows the 7 million molecules non‐Lipinski PubChem chemical space color‐coded by carbon fraction, which well separates the different compound... 
databases | visualization | chemical space | biomolecules | fingerprints
Journal Article
Nucleic acids research, ISSN 0305-1048, 2004, Volume 32, Issue 14, pp. e115 - e115
We have developed a new primer design method based on the QuickChange(TM) site-directed mutagenesis protocol, which significantly improves the PCR... 
EVOLUTION | PROTEIN | BIOCHEMISTRY & MOLECULAR BIOLOGY | PCR | Mutagenesis, Site-Directed | Gene Library | Protein Engineering - methods | Electrophoresis, Agar Gel | Polymerase Chain Reaction | Directed Molecular Evolution | DNA Primers | Index Medicus | NAR Methods Online
Journal Article
Nucleic Acids Research, ISSN 0305-1048, 07/2014, Volume 42, Issue 1, pp. W234 - W239
To confirm the activity of an initial small molecule 'hit compound' from an activity screening, one needs to probe the structure-activity relationships by... 
SPACE | VISUALIZATION | ORGANIC-MOLECULES | SHAPE | PHARMACOPHORE SEARCH | PERFORMANCE | BIOCHEMISTRY & MOLECULAR BIOLOGY | DRUG DISCOVERY | CHEMICAL UNIVERSE DATABASE | SELECTION | DESCRIPTORS | Software | Structure-Activity Relationship | Internet | Databases, Chemical | Drug Discovery | Pharmaceutical Preparations - chemistry | Index Medicus
Journal Article
Journal of cheminformatics, ISSN 1758-2946, 2016, Volume 8, p. 25
Similarly to the periodic table for elements, chemical space offers an organizing principle for representing the diversity of organic molecules, usually in the... 
Journal Article
ISSN 0306-0012, 5/2013, Volume 42, Issue 11, pp. 4814 - 4822
Synthetic glycopeptide dendrimers composed of a branched oligopeptide tree structure appended with glycosidic groups at its multiple N-termini were... 
Journal Article
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