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Oncotarget, ISSN 1949-2553, 06/2019, Volume 10, Issue 39, pp. 3831 - 3832
Journal Article
Anticancer Research, ISSN 0250-7005, 03/2019, Volume 39, Issue 3, pp. 1197 - 1204
Journal Article
Cancer Research, ISSN 0008-5472, 07/2018, Volume 78, Issue 13 Supplement, pp. 4025 - 4025
Journal Article
by Shungin, Dmitry and Winkler, Thomas W and Croteau-Chonka, Damien C and Ferreira, Teresa and Locke, Adam E and Mägi, Reedik and Strawbridge, Rona J and Pers, Tune H and Fischer, Krista and Justice, Anne E and Workalemahu, Tsegaselassie and Wu, Joseph M. W and Buchkovich, Martin L and Heard-Costa, Nancy L and Roman, Tamara S and ng, Alexander W and Song, Ci and Gustafsson, Stefan and Day, Felix R and Esko, Tonu and Fall, Tove and Kutalik, Zoltán and Luan, Jian'an and Randall, Joshua C and Scherag, Ané and Vedantam, Sailaja and Wood, Anew R and Chen, Jin and Fehrmann, Rudolf and Karjalainen, Juha and Kahali, Bratati and Liu, Ching-Ti and Schmidt, Ellen M and Absher, Devin and Amin, Najaf and Anderson, Denise and Beekman, Marian and Bragg-Gresham, Jennifer L and Buyske, Steven and Demirkan, Ayse and Ehret, Georg B and Feitosa, Mary F and Goel, Anuj and Jackson, Anne U and Johnson, Toby and Kleber, Marcus E and Kristiansson, Kati and Mangino, Massimo and Mateo Leach, Irene and Medina-Gomez, Carolina and Palmer, Cameron D and Pasko, Dorota and Pechlivanis, Sonali and Peters, Marjolein J and Prokopenko, Inga and Stančáková, Alena and Ju Sung, Yun and Tanaka, Toshiko and Teumer, Alexander and van Vliet-Ostaptchouk, Jana V and Yengo, Loïc and Zhang, Weihua and Albrecht, Eva and Ärnlöv, Johan and Arscott, Gillian M and Bandinelli, Stefania and Barrett, Amy and Bellis, Claire and Bennett, Amanda J and Berne, Christian and Blüher, Matthias and Böhringer, Stefan and Bonnet, Fabrice and Böttcher, Yvonne and Bruinenberg, Marcel and Carba, Delia B and Caspersen, Ida H and Clarke, Robert and Daw, E. Warwick and Deelen, Joris and Deelman, Ewa and Delgado, Graciela and Doney, Alex S. F and Eklund, Niina and Erdos, Michael R and Estrada, Karol and Eury, Elodie and Frieich, Nele and Garcia, Melissa E and Gieaitis, Vilmantas and Gigante, Bruna and Go, Alan S and Golay, Alain and Grallert, Harald and Grammer, Tanja B and Gräßler, Jürgen and Grewal, Jagvir and Groves, Christopher J and Haller, Toomas and Hallmans, Goran and ... and PAGE Consortium and LifeLines Cohort Study and CARDIOGRAMplusC4D Consortium and MuTHER Consortium and ICBP and ADIPOGEN Consortium and CKDGen Consortium and GEFOS Consortium and Int Endogene Consortium and GENIE Consortium and MAGIC Investigators and ReproGen Consortium and GLGC and ADIPOGen Consortium and International Endogene Consortium and The PAGE Consortium and The International Endogene Consortium and The MAGIC Investigators and The ReproGen Consortium and The CKDGen Consortium and The ADIPOGen Consortium and The ICBP and The CARDIOGRAMplusC4D Consortium and The GENIE Consortium and The GLGC and The GEFOS Consortium and The MuTHER Consortium and The LifeLines Cohort Study and Högskolan Dalarna and Akademin Utbildning, hälsa och samhälle and Medicinsk vetenskap
Nature, ISSN 0028-0836, 2015, Volume 518, Issue 7538, pp. 187 - U378
Body fat distribution is a heritable trait and a well-established predictor of adverse metabolic outcomes, independent of overall adiposity. To increase our... 
HUMAN HEIGHT | ABDOMINAL ADIPOSITY | MULTIDISCIPLINARY SCIENCES | COMMON SNPS | SUSCEPTIBILITY LOCI | GLYCEMIC TRAITS | FALSE DISCOVERY | MESENCHYMAL STEM-CELLS | GENOME-WIDE ASSOCIATION | ADIPOGENIC DIFFERENTIATION | SEXUAL-DIMORPHISM | Body Mass Index | Genome-Wide Association Study | Age Factors | Neovascularization, Physiologic - genetics | Epigenesis, Genetic | Humans | Male | Continental Population Groups - genetics | Sex Characteristics | Obesity - genetics | Europe - ethnology | Genome, Human - genetics | Adipose Tissue - metabolism | Insulin - metabolism | Models, Biological | Adipocytes - metabolism | Insulin Resistance - genetics | Polymorphism, Single Nucleotide - genetics | Female | Body Fat Distribution | Transcription, Genetic - genetics | Adipogenesis - genetics | Waist-Hip Ratio | Quantitative Trait Loci - genetics | Adipose tissues | Quantitative trait loci | Genetic research | Genetic aspects | Research | Metabolism | Health aspects | Studies | Body mass index | Genealogy | Body fat | Insulin resistance | Genetics | Genomes | Abdomen | Meta-analysis | Index Medicus | Life Sciences | Adipocytes/metabolism Adipogenesis/genetics Adipose Tissue/metabolism Age Factors Body Fat Distribution Body Mass Index Continental Population Groups/genetics Epigenesis, Genetic Europe/ethnology Female Genome, Human/genetics Genome-Wide Association Study Humans Insulin/metabolism Insulin Resistance/genetics Male Models, Biological Neovascularization, Physiologic/genetics Obesity/genetics Polymorphism, Single Nucleotide/genetics Quantitative Trait Loci/genetics Sex Characteristics Transcription, Genetic/genetics Waist-Hip Ratio | Clinical Medicine | Hälsa och välfärd | Medical and Health Sciences | Klinisk medicin | Medicin och hälsovetenskap | Health and Welfare
Journal Article
Current Pathobiology Reports, ISSN 2167-485X, 6/2016, Volume 4, Issue 2, pp. 37 - 46
The epithelial linings of eukaryotic organs form dynamically-regulated selectively-permeable barriers that control the movement of substances into (and out of)... 
Pathology | Signaling | Medicine & Public Health | Tight junction | Apical junctional complex | Tumorigenesis | Adhesion | Cancer
Journal Article
Cellular Oncology, ISSN 2211-3428, 2/2018, Volume 41, Issue 1, pp. 35 - 46
Triple-negative breast cancers (TNBC) lack expression of three common cell surface receptors, i.e., estrogen receptor (ER), progesterone receptor (PR) and... 
Biomedicine, general | Crassin | Reactive oxygen species | Oncology | Cell viability | Breast cancer | Antioxidant | Doxorubicin | Synergism | Cells | Pathology | Biomedicine | Cytostasis | Cancer Research | Diterpenoid,(4E,8E)-2,10-dihydroxy-4,8,12-trimethyl-16-methylidene-14-oxabicyclo Heptadeca-4,8-dien-15-one | Cancer | Diterpenoid,(4E,8E)-2,10-dihydroxy-4,8,12-trimethyl-16-methylidene-14-oxabicyclo[11.3.1] Heptadeca-4,8-dien-15-one | SURVIVAL | APOPTOSIS | ACTIVATION | DEATH MECHANISMS | AKT | RELEASE | PATHOLOGY | CELL BIOLOGY | ONCOLOGY | TAXOL | NEURONS | INHIBITOR | ERK | Cell Survival - drug effects | Reactive Oxygen Species - metabolism | Humans | Antioxidants - pharmacology | Extracellular Signal-Regulated MAP Kinases - metabolism | Triple Negative Breast Neoplasms - metabolism | Triple Negative Breast Neoplasms - pathology | Female | Antineoplastic Agents - pharmacology | Tumor Cells, Cultured | Cytostatic Agents - pharmacology | Proto-Oncogene Proteins c-akt - metabolism | Doxorubicin - pharmacology | Triple Negative Breast Neoplasms - enzymology | Phosphorylation | Estrogen receptors | Acetylcysteine | Cytotoxicity | AKT protein | Autophagy | Cell surface | Western blotting | Necrosis | Antioxidants | Epidermal growth factor | Gangrene | Species | Oxygen | Cell survival | Extracellular signal-regulated kinase | ErbB-2 protein | Biological activity | Cell death | Medical prognosis | Cell lines | N-Acetyl-L-cysteine | Phagocytosis | Apoptosis | Index Medicus
Journal Article
Nature Communications, ISSN 2041-1723, 07/2017, Volume 8, Issue 1, pp. 16015 - 16015
textabstractHand grip strength is a widely used proxy of muscular fitness, a marker of frailty, and predictor of a range of morbidities and all-cause... 
SKELETAL-MUSCLE | METAANALYSIS | VARIANTS | GROWTH-FACTOR-ALPHA | MULTIDISCIPLINARY SCIENCES | DISEASE | FRACTURES | GENETIC INFLUENCES | MENDELIAN RANDOMIZATION | INSTRUMENTS | GENOME-WIDE ASSOCIATION | Genetics, Population | European Continental Ancestry Group - genetics | Genome-Wide Association Study | Membrane Proteins - genetics | Humans | Middle Aged | Repressor Proteins - genetics | Male | United Kingdom | Genetic Loci | Transforming Growth Factor alpha - genetics | Actins - genetics | Adult | Female | Aged | Polymorphism, Single Nucleotide | Neoplasm Proteins - genetics | Nuclear Proteins - genetics | Hand - physiology | Hand Strength | Cohort Studies | Mortality | Disorders | Product design | Genetic diversity | Loci | Skeletal muscle | Wrist | Signal transduction | Psychomotor performance | Transduction | Grip strength | Muscular strength | Age | Fitness | Structure-function relationships | Index Medicus | Genetik | Basic Medicine | Medical Genetics | Medicinsk genetik | Biological Sciences | Naturvetenskap | Medical and Health Sciences | Medicin och hälsovetenskap | Biologiska vetenskaper | Medicinska och farmaceutiska grundvetenskaper | Genetics | Natural Sciences | HNE Voeding en Gezondheid in de Levenscyclus | Wereldvoeding | VLAG | Chair Nutrition and Health over the Lifecourse | Global Nutrition | HNE Nutrition and Health over the Lifecourse
Journal Article
by Willems, Sara M and Wright, D.J and Day, Felix R and Trajanoska, Katerina and Joshi, P.K and Morris, John A and Matteini, Amy M and Garton, Fleur C and Grarup, Niels and Oskolkov, Nikolay and Thalamuthu, Anbupalam and Mangino, Massimo and Liu, Jun and Demirkan, Ayse and Lek, Monkol and Xu, Liwen and Wang, Guan and Oldmeadow, Christopher and Gaulton, Kyle J and Lotta, Luca A and Miyamoto-Mikami, Eri and Rivas, Manuel A and White, Tom and Loh, Po Ru and Aadahl, Mette and Amin, Najaf and Attia, John R and Austin, Krista and Benyamin, Beben and Brage, Søren and Cheng, Yu Ching and Ciȩszczyk, Paweł and Derave, Wim and Eriksson, Karl Freik and Eynon, Nir and Linneberg, Allan and Lucia, Alejano and Massidda, Myosotis and Mitchell, Braxton D and Miyachi, Motohiko and Murakami, Haruka and Padmanabhan, Sandosh and Pandey, Ashutosh and Papadimitriou, Ioannis and Rajpal, Deepak K and Sale, Craig and Schnurr, Theresia M and Sessa, Francesco and Shrine, Nick and Tobin, Martin D and Varley, Ian and Wain, Louise V and Wray, Naomi R and Lindgren, Cecilia M and MacArthur, Daniel G and Waterworth, Dawn M and McCarthy, Mark I and Pedersen, Oluf and Khaw, Kay Tee and Kiel, Douglas P and Pitsiladis, Yannis and Fuku, Noriyuki and Franks, Paul W and North, Kathryn N and Duijn, Van, C.M and Mather, Karen A and Hansen, Torben and Hansson, Ola and Spector, Tim D and Murabito, Joanne M and Richards, J.B and Rivadeneira, Fernando and Langenberg, Claudia and Perry, John R.B and Wareham, Nick J and Scott, Robert A and Oei, Ling and Zheng, Hou Feng and Forgetta, Vincenzo and Leong, Aaron and Ahmad, Omar S and Laurin, Charles and Mokry, Lauren E and Ross, Stephanie and Elks, Cathy E and Bowden, Jack and Warrington, Nicole M and Murray, Anna and Ruth, Katherine S and Tsilidis, Konstantinos K and Medina-Gómez, Carolina and Estrada, Karol and Bis, Joshua C and Chasman, Daniel I and Demissie, Serkalem and Enneman, Anke W and Hsu, Yi Hsiang and Ingvarsson, Thorvaldur and Kähönen, Mika and Kammerer, Candace and ... and Göteborgs universitet and Gothenburg University and Institutionen för medicin, avdelningen för invärtesmedicin och klinisk nutrition and Sahlgrenska Academy and Centre for Bone and Arthritis Research and Sahlgrenska akademin and Institute of Medicine, Department of Internal Medicine and Clinical Nutrition
Nature Communications, ISSN 2041-1723, 2017, Volume 8
Hand grip strength is a widely used proxy of muscular fitness, a marker of frailty, and predictor of a range of morbidities and all-cause mortality. To... 
Klinisk medicin | Clinical Medicine
Journal Article
by Thorsson, Vesteinn and Thorsson, Vésteinn and Gibbs, Richard A and Gibbs, David L and Brown, Scott D and Wolf, Gregory and Wolf, Denise and Bortone, Dante S and Ou Yang, Tai-Hsien and Porta-Pardo, Eduard and Gao, Galen F and Gao, Jianjiong and Plaisier, Christopher L and Eddy, James A and Ziv, Elad and Culhane, Aedin C and Paull, Evan O and Sivakumar, I.K. Ashok and Gentles, Andrew J and Malhotra, Raunaq and Farshidfar, Farshad and Colaprico, Antonio and Parker, Joel S and Mose, Lisle E and Vo, Nam Sy and Liu, Wenbin and Liu, Jianfang and Liu, Jia and Liu, Yuexin and Liu, Xiuping and Rader, Janet and Dhankani, Varsha and Reynolds, Sheila and Reynolds, Sheila M and Bowlby, Reanne and Califano, Andrea and Cherniack, Andrew D and Anastassiou, Dimitris and Bedognetti, Davide and Mokrab, Younes and Newman, Aaron M and Rao, Arvind and Chen, Amy and Chen, Chu and Chen, Ken and Krasnitz, Alexander and Hu, Jianhong and Hu, Hai and Malta, Tathiane M and Noushmehr, Houtan and Pedamallu, Chandra Sekhar and Bullman, Susan and Ojesina, Akinyemi I and Lamb, Andrew and Zhou, Wanding and Shen, Hui and Choueiri, Toni K and Weinstein, John N and Guinney, Justin and Saltz, Joel and Holt, Robert and Holt, Robert A and Rabkin, Charles S and Caesar-Johnson, Samantha J and Demchok, John A and Felau, Ina and Kasapi, Melpomeni and Ferguson, Martin L and Hutter, Carolyn M and Sofia, Heidi J and Tarnuzzer, Roy and Wang, Jioajiao and Wang, Min and Wang, Linghua and Wang, Zhining and Wang, Timothy and Wang, Jing and Yang, Ju Dong and Yang, Hannah and Yang, Liming and Yang, Ian and Zenklusen, Jean C and Zhang, Jiashan (Julia) and Zhang, Jiexin and Zhang, Lizhi and Zhang, Wei and Zhang, Hongzheng and Zhang, Hailei and Zhang, Hongxin and Chudamani, Sudha and Lolla, Laxmi and Naresh, Rashi and Pihl, Todd and Sun, Yichao and Sun, Qiang and Wan, Yunhu and Wu, Ye and Cho, Juok and DeFreitas, Timothy and Frazer, Scott and ... and Canc Genome Atlas Res Network and Cancer Genome Atlas Research Network
Immunity, ISSN 1074-7613, 04/2018, Volume 48, Issue 4, pp. 812 - 830.e14
We performed an extensive immunogenomic analysis of more than 10,000 tumors comprising 33 diverse cancer types by utilizing data compiled by TCGA. Across... 
tumor immunology | immunotherapy | cancer genomics | integrative network analysis | immuno-oncology | tumor microenvironment | immune subtypes | immunomodulatory |