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1. Full Text Commentary: Orienting causal relationships between two phenotypes using bidirectional Mendelian randomization
by Richmond, Rebecca C and Davey Smith, George
International Journal of Epidemiology, ISSN 0300-5771, 06/2019, Volume 48, Issue 3, pp. 907 - 911
Index Medicus
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2. Full Text RE: Prenatal smoke exposure, DNA methylation and a link between DRD1 and lung cancer
by Richmond, Rebecca C and Suderman, Matthew and Langdon, Ryan and Relton, Caroline L and Davey Smith, George
International journal of epidemiology, ISSN 0300-5771, 03/2019
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3. Full Text An integrative approach to detect epigenetic mechanisms that putatively mediate the influence of lifestyle exposures on disease susceptibility
by Richardson, Tom G and Richmond, Rebecca C and North, Teri-Louise and Hemani, Gibran and Davey Smith, George and Sharp, Gemma C and Relton, Caroline L
International Journal of Epidemiology, ISSN 0300-5771, 06/2019, Volume 48, Issue 3, pp. 887 - 898
BACKGROUNDThere is mounting evidence that our environment and lifestyle has an impact on epigenetic regulatory mechanisms, such as DNA methylation. It has been... 
Index Medicus
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4. Full Text Prenatal exposure to maternal smoking and offspring DNA methylation across the lifecourse: Findings from the Avon Longitudinal Study of Parents and Children (ALSPAC)
by Richmond, Rebecca C and Simpkin, Andrew J and Woodward, Geoff and Gaunt, Tom R and Lyttleton, Oliver and McArdle, Wendy L and Ring, Susan M and Smith, Andrew D.A.C and Timpson, Nicholas J and Tilling, Kate and Smith, George Davey and Relton, Caroline L
Human Molecular Genetics, ISSN 0964-6906, 04/2015, Volume 24, Issue 8, pp. 2201 - 2217
Maternal smoking during pregnancy has been found to influence newborn DNA methylation in genes involved in fundamental developmental processes. It is pertinent... 
IN-UTERO | CIGARETTE-SMOKING | ASSOCIATIONS | GENE-CLUSTER | LOW-BIRTH-WEIGHT | AHRR METHYLATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | GENETICS & HEREDITY | EPIGENOME | BLOOD-PRESSURE | DISCOVERY | PREGNANCY | Smoking - adverse effects | Humans | Infant | Male | Prenatal Exposure Delayed Effects - metabolism | Pregnancy | Prenatal Exposure Delayed Effects - genetics | DNA Methylation | Pedigree | Adolescent | Maternal Exposure - adverse effects | Female | Child | Longitudinal Studies | Infant, Newborn | Cohort Studies | Index Medicus
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5. Full Text Maternal pre-pregnancy BMI and gestational weight gain, offspring DNA methylation and later offspring adiposity: Findings from the Avon Longitudinal Study of Parents and Children
by Sharp, Gemma C and Lawlor, Debbie A and Richmond, Rebecca C and Fraser, Abigail and Simpkin, Andrew and Suderman, Matthew and Shihab, Hashem A and Lyttleton, Oliver and McArdle, Wendy and Ring, Susan M and Gaunt, Tom R and Smith, George Davey and Relton, Caroline L
International Journal of Epidemiology, ISSN 0300-5771, 08/2015, Volume 44, Issue 4, pp. 1288 - 1304
Background: Evidence suggests that in utero exposure to undernutrition and overnutrition might affect adiposity in later life. Epigenetic modification is... 
Longitudinal | ALSPAC | Epigenome-wide association study | Epigenetic | ARIES | Causality | Overnutrition | Undernutrition | Overweight | epigenome-wide association study | PRENATAL FAMINE | undernutrition | causality | overnutrition | PREGNANCY | OBESITY | PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH | NUTRITION | BIRTH | longitudinal | PROMOTER | overweight | EXPOSURE | Body Mass Index | Genome-Wide Association Study | Maternal Nutritional Physiological Phenomena | Humans | Male | Thinness | United Kingdom | Adiposity - genetics | Obesity - genetics | Pregnancy | DNA Methylation | Adolescent | Female | Weight Gain | Child | Longitudinal Studies | Index Medicus | Adiposity
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6. Full Text Toll-like receptor 2 ligands inhibit T H2 responses to mite allergen
by Taylor, Rebecca C and Richmond, Peter and Upham, John W
The Journal of Allergy and Clinical Immunology, ISSN 0091-6749, 2006, Volume 117, Issue 5, pp. 1148 - 1154
There is intense interest in the interaction between microbial compounds and allergy. Although Toll-like receptor (TLR)–2 ligands derived from Gram-positive... 
Toll-like receptors | innate immunity | T H2 cytokines | Atopy | 2 cytokines
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7. Full Text Assessing Causality in the Association between Child Adiposity and Physical Activity Levels: A Mendelian Randomization Analysis
by Richmond, Rebecca C and Davey Smith, George and Ness, Andy R and den Hoed, Marcel and McMahon, George and Timpson, Nicholas J and Medicinska fakulteten and Science for Life Laboratory, SciLifeLab and Medicinska och farmaceutiska vetenskapsområdet and Uppsala universitet and Institutionen för medicinska vetenskaper and Molekylär epidemiologi
PLoS Medicine, ISSN 1549-1277, 2014, Volume 11, Issue 3, pp. e1001618 - e1001618
Background Cross-sectional studies have shown that objectively measured physical activity is associated with childhood adiposity, and a strong inverse... 
POPULATION | MEDICINE, GENERAL & INTERNAL | OBESITY | INTERVENTIONS | INSTRUMENTAL VARIABLES | BODY-MASS INDEX | ADOLESCENCE | BLOOD-PRESSURE | FAT MASS | GENOME-WIDE ASSOCIATION | CARDIOVASCULAR RISK-FACTORS | Body Mass Index | Adiposity | Humans | Mendelian Randomization Analysis | England | Female | Male | Motor Activity | Absorptiometry, Photon | Child | Longitudinal Studies | Medical research | Exercise | Causation | Medicine, Experimental | Research | Children | Health aspects | Index Medicus | Medical and Health Sciences | Medicin och hälsovetenskap | Studies | Obesity | Body mass index | Weight control | Physical fitness
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8. Full Text Epigenome-wide association study of body mass index, and the adverse outcomes of adiposity
by Wahl, Simone and Drong, Alexander and Lehne, Benjamin and Loh, Marie and Scott, William R and Kunze, Sonja and Tsai, Pei-Chien and Ried, Janina S and Zhang, Weihua and Yang, Youwen and Tan, Sili and Fiorito, Giovanni and Franke, Lude and Guarrera, Simonetta and Kasela, Silva and Kriebel, Jennifer and Richmond, Rebecca C and Adamo, Marco and Afzal, Uzma and Ala-Korpela, Mika and Albetti, Benedetta and Ammerpohl, Ole and Apperley, Jane F and Beekman, Marian and Bertazzi, Pier Alberto and Black, S. Lucas and Blancher, Christine and Bonder, Marc-Jan and Brosch, Mario and Carstensen-Kirberg, Maren and De Craen, Anton J.M and De Lusignan, Simon and Dehghan, Abbas and Elkalaawy, Mohamed and Fischer, Krista and Franco, Oscar H and Gaunt, Tom R and Hampe, Jochen and Hashemi, Majid and Isaacs, Aaron and Jenkinson, Andrew and Jha, Sujeet and Kato, Norihiro and Krogh, Vittorio and Laffan, Michael and Meisinger, Christa and Meitinger, Thomas and Mok, Zuan Yu and Motta, Valeria and Ng, Hong Kiat and Nikolakopoulou, Zacharoula and Nteliopoulos, Georgios and Panico, Salvatore and Pervjakova, Natalia and Prokisch, Holger and Rathmann, Wolfgang and Roden, Michael and Rota, Federica and Rozario, Michelle Ann and Sandling, Johanna K and Schafmayer, Clemens and Schramm, Katharina and Siebert, Reiner and Slagboom, P. Eline and Soininen, Pasi and Stolk, Lisette and Strauch, Konstantin and Tai, E-Shyong and Tarantini, Letizia and Thorand, Barbara and Tigchelaar, Ettje F and Tumino, Rosario and Uitterlinden, Andre G and Van Duijn, Cornelia and Van Meurs, Joyce B.J and Vineis, Paolo and Wickremasinghe, Ananda Rajitha and Wijmenga, Cisca and Yang, Tsun-Po and Yuan, Wei and Zhernakova, Alexandra and Batterham, Rachel L and Smith, George Davey and Deloukas, Panos and Heijmans, Bastiaan T and Herder, Christian and Hofman, Albert and Lindgren, Cecilia M and Milani, Lili and Van Der Harst, Pim and Peters, Annette and Illig, Thomas and Relton, Caroline L and Waldenberger, Melanie and Järvelin, Marjo-Riitta and Bollati, Valentina and Soong, Richie and Spector, Tim D and Scott, James and McCarthy, Mark I and ... and Medicinska fakulteten and Science for Life Laboratory, SciLifeLab and Medicinska och farmaceutiska vetenskapsområdet and Molekylär medicin and Uppsala universitet and Institutionen för medicinska vetenskaper
Nature, ISSN 0028-0836, 01/2017, Volume 541, Issue 7635, pp. 81 - 86
Approximately 1.5 billion people worldwide are overweight or affected by obesity, and are at risk of developing type (2) diabetes, cardiovascular disease and... 
OBESITY | DNA METHYLATION | GLUCOSE | MULTIDISCIPLINARY SCIENCES | DISEASE | TISSUE | HUMANS | BARIATRIC SURGERY | MENDELIAN RANDOMIZATION | HEALTH | TRENDS | Overweight - complications | Diabetes Mellitus, Type 2 - genetics | Epigenesis, Genetic | Humans | Asian Continental Ancestry Group - genetics | India - ethnology | Male | Blood - metabolism | Obesity - blood | Obesity - genetics | Europe - ethnology | Adipose Tissue - metabolism | Female | Diabetes Mellitus, Type 2 - complications | Body Mass Index | European Continental Ancestry Group - genetics | Genetic Predisposition to Disease | Genome-Wide Association Study | Epigenomics | Obesity - complications | Overweight - genetics | DNA Methylation - genetics | Genetic Markers | Adiposity - genetics | Overweight - blood | Cohort Studies | Epigenetic inheritance | Body mass index | Obesity | Genome-wide association studies | Genetic aspects | Health aspects | Neutrophils | Cardiovascular disease | Metabolism | Gene expression | Asthma | Studies | DNA methylation | Epigenetics | Population | Gene loci | Diabetes | Deoxyribonucleic acid--DNA | Asians | Index Medicus | Clinical Medicine | Medical and Health Sciences | Endokrinologi och diabetes | Medicin och hälsovetenskap | General Practice | Allmänmedicin | Klinisk medicin | Endocrinology and Diabetes
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9. Full Text BMI as a modifiable risk factor for type 2 diabetes: Refining and understanding causal estimates using mendelian randomization
by Corbin, Laura J and Richmond, Rebecca C and Wade, Kaitlin H and Burgess, Stephen and Bowden, Jack and Smith, George Davey and Timpson, Nicholas J
Diabetes, ISSN 0012-1797, 10/2016, Volume 65, Issue 10, pp. 3002 - 3007
This study focused on resolving the relationship between BMI and type 2 diabetes. The availability of multiple variants associated with BMI offers a new chance... 
REGRESSION | ENDOCRINOLOGY & METABOLISM | BODY-MASS INDEX | INFERENCE | TRAITS | ASSOCIATION | INSTRUMENTS | INSIGHTS | Body Mass Index | Genetic Predisposition to Disease - genetics | Transcription Factor 7-Like 2 Protein - genetics | Diabetes Mellitus, Type 2 - genetics | Humans | Risk Factors | Mendelian Randomization Analysis | Genetic Pleiotropy - genetics | Odds Ratio | Diabetes Mellitus, Type 2 - epidemiology | Type 2 diabetes | Body mass index | Genetic aspects | Health aspects | Risk factors | Genetic diversity | Diabetes | Causality | Index Medicus | Abridged Index Medicus
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10. Full Text Associations of device-measured physical activity across adolescence with metabolic traits: Prospective cohort study
by Bell, Joshua A and Hamer, Mark and Richmond, Rebecca C and Timpson, Nicholas J and Carslake, David and Davey Smith, George
PLoS medicine, ISSN 1549-1277, 09/2018, Volume 15, Issue 9, p. e1002649
Multiple occasions of device-measured physical activity have not been previously examined in relation to metabolic traits. We described associations of total... 
Metabolomics | Prospective Studies | Humans | Metabolome | Male | Adolescent Health | Exercise | Adolescent | Female | Child | Accelerometry | Cohort Studies | Sedentary Behavior | Type 2 diabetes | Adolescence | Physical fitness | Low density lipoproteins | Analysis | Physiological aspects | Nuclear magnetic resonance spectroscopy | Triglycerides | Fatty acids
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11. Full Text DNA Methylation in Newborns and Maternal Smoking in Pregnancy: Genome-wide Consortium Meta-analysis
by Joubert, Bonnie R and Felix, Janine F and Yousefi, Paul and Bakulski, Kelly M and Just, Allan C and Breton, Carrie and Reese, Sarah E and Markunas, Christina A and Richmond, Rebecca C and Xu, Cheng-Jian and Xu, Zongli and Küpers, Leanne K and Oh, Sam S and Hoyo, Cathrine and Gruzieva, Olena and Söderhäll, Cilla and Salas, Lucas A and Baïz, Nour and Zhang, Hongmei and Lepeule, Johanna and Ruiz, Carlos and Ligthart, Symen and Wang, Tianyuan and Taylor, Jack A and Duijts, Liesbeth and Sharp, Gemma C and Jankipersadsing, Soesma A and Nilsen, Roy M and Vaez, Ahmad and Fallin, M. Daniele and Hu, Donglei and Litonjua, Augusto A and Fuemmeler, Bernard F and Huen, Karen and Kere, Juha and Kull, Inger and Munthe-Kaas, Monica Cheng and Gehring, Ulrike and Bustamante, Mariona and Saurel-Coubizolles, Marie José and Quraishi, Bilal M and Ren, Jie and Tost, Jörg and Gonzalez, Juan R and Peters, Marjolein J and Håberg, Siri E and van Meurs, Joyce B and Gaunt, Tom R and Kerkhof, Marjan and Corpeleijn, Eva and Feinberg, Andrew P and Eng, Celeste and Baccarelli, Andrea A and Benjamin Neelon, Sara E and Bradman, Asa and Merid, Simon Kebede and Bergström, Anna and Herceg, Zdenko and Hernandez-Vargas, Hector and Brunekreef, Bert and Pinart, Mariona and Heude, Barbara and Ewart, Susan and Yao, Jin and Lemonnier, Nathanaël and Franco, Oscar H and Wu, Michael C and Hofman, Albert and McArdle, Wendy and Van der Vlies, Pieter and Falahi, Fahimeh and Gillman, Matthew W and Barcellos, Lisa F and Kumar, Ashish and Wickman, Magnus and Guerra, Stefano and Charles, Marie-Aline and Holloway, John and Auffray, Charles and Tiemeier, Henning W and Smith, George Davey and Postma, Dirkje and Hivert, Marie-France and Eskenazi, Brenda and Vrijheid, Martine and Arshad, Hasan and Antó, Josep M and Dehghan, Abbas and Karmaus, Wilfried and Annesi-Maesano, Isabella and Sunyer, Jordi and Ghantous, Akram and Pershagen, Göran and Holland, Nina and Murphy, Susan K and DeMeo, Dawn L and Burchard, Esteban G and Ladd-Acosta, Christine and Snieder, Harold and Nystad, Wenche and ...
The American Journal of Human Genetics, ISSN 0002-9297, 04/2016, Volume 98, Issue 4, pp. 680 - 696
Epigenetic modifications, including DNA methylation, represent a potential mechanism for environmental impacts on human disease. Maternal smoking in pregnancy... 
BREAST-CANCER | IN-UTERO | CIGARETTE-SMOKING | LYMPH-NODE METASTASIS | PRENATAL EXPOSURE | TOBACCO-SMOKING | GENETICS & HEREDITY | LUNG-FUNCTION DECLINE | NEUROPILIN-2 EXPRESSION | AUTISM SPECTRUM DISORDERS | POSTSYNAPTIC DENSITY | Smoking - adverse effects | European Continental Ancestry Group - genetics | Genetic Association Studies | Epigenesis, Genetic | Humans | Child, Preschool | Infant | Chromosome Mapping | Cleft Palate - genetics | Asthma - genetics | Pregnancy | Cleft Lip - genetics | DNA Methylation | Cleft Palate - etiology | Female | Asthma - etiology | Child | Infant, Newborn | Cleft Lip - etiology | Genome-wide association studies | Genetic aspects | Nucleotide sequencing | Methylation | Health aspects | Methods | DNA sequencing | Smoking | Newborn babies | DNA methylation | Genomes | Mothers | Meta-analysis | Index Medicus
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12. Full Text Challenges and novel approaches for investigating molecular mediation
by Richmond, R.C and Hemani, G and Tilling, K and Davey Smith, G and Relton, C.L
Human Molecular Genetics, ISSN 0964-6906, 10/2016, Volume 25, Issue 2, pp. R149 - R156
Understanding mediation is useful for identifying intermediates lying between an exposure and an outcome which, when intervened upon, will block (some or all... 
DENSITY-LIPOPROTEIN CHOLESTEROL | DNA METHYLATION | MEASUREMENT ERROR | CAUSAL INFERENCE | BIOCHEMISTRY & MOLECULAR BIOLOGY | GENETICS & HEREDITY | GENETIC-VARIANTS | MENDELIAN RANDOMIZATION | COMPLEX TRAITS | EPIGENOME-WIDE ASSOCIATION | BLOOD-PRESSURE | INSTRUMENTS | Invited Reviews
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