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1. Full Text Predictive Value of Known and Novel Alleles of CYP2B6 for Efavirenz Plasma Concentrations in HIV‐infected Individuals
by Rotger, M and Tegude, H and Colombo, S and Cavassini, M and Furrer, H and Décosterd, L and Blievernicht, J and Saussele, T and Günthard, H F and Schwab, M and Eichelbaum, M and Telenti, A and Zanger, U M and Swiss HIV Cohort Study
Clinical Pharmacology & Therapeutics, ISSN 0009-9236, 04/2007, Volume 81, Issue 4, pp. 557 - 566
To assess the association of CYP2B6 allelic diversity with efavirenz (EFV) pharmacokinetics, we performed extensive genotyping of 15 relevant single nucleotide... 
GENE | PHARMACOKINETICS | CONTAINING REGIMENS | PHARMACOLOGY & PHARMACY | POLYMORPHISM | CATALYTIC-ACTIVITY | ANDROSTANE-RECEPTOR | EXPRESSION | HUMAN-LIVER | CYTOCHROME P4502B6 | BUPROPION HYDROXYLATION | Predictive Value of Tests | Oxidoreductases, N-Demethylating - genetics | Prospective Studies | Area Under Curve | Humans | Aryl Hydrocarbon Hydroxylases - genetics | Cercopithecus aethiops | Male | Benzoxazines | Plasmids - genetics | Adult | Female | Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | Anti-HIV Agents - blood | HIV Infections - blood | HIV Infections - genetics | Exons - genetics | Genotype | Blotting, Western | Animals | Alleles | Polymorphism, Single Nucleotide | COS Cells | Oxazines - blood | Cytochrome P-450 CYP2B6
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2. Full Text Evolving antithrombotic treatment patterns for patients with newly diagnosed atrial fibrillation
by Camm, A John and Accetta, Gabriele and Ambrosio, Giuseppe and Atar, Dan and Bassand, Jean-Pierre and Berge, Eivind and Cools, Frank and Fitzmaurice, David A and Goldhaber, Samuel Z and Goto, Shinya and Haas, Sylvia and Kayani, Gloria and Koretsune, Yukihiro and Mantovani, Lorenzo G and Misselwitz, Frank and Oh, Seil and Turpie, Alexander G G and Verheugt, Freek W A and Kakkar, Ajay K and GARFIELD-AF Investigators
Heart, ISSN 1355-6037, 02/2017, Volume 103, Issue 4, pp. 307 - 314
ObjectiveWe studied evolving antithrombotic therapy patterns in patients with newly diagnosed non-valvular atrial fibrillation (AF) and ≥1 additional stroke... 
CARDIAC & CARDIOVASCULAR SYSTEMS | THERAPY | STROKE PREVENTION | RISK-FACTOR | WARFARIN | TRANSIENT ISCHEMIC ATTACK | GLOBAL ANTICOAGULANT REGISTRY | GUIDELINES | EURO HEART SURVEY | SUBGROUP ANALYSIS | THROMBOEMBOLISM | Prospective Studies | Age Factors | Humans | Middle Aged | Stroke - diagnosis | Male | Fibrinolytic Agents - adverse effects | Time Factors | Aged, 80 and over | Female | Registries | Stroke - epidemiology | Atrial Fibrillation - diagnosis | Stroke - prevention & control | Risk Assessment | Administration, Oral | Atrial Fibrillation - drug therapy | Comorbidity | Risk Factors | Treatment Outcome | Practice Patterns, Physicians' - trends | Guideline Adherence | Atrial Fibrillation - epidemiology | Sex Factors | Aged | Fibrinolytic Agents - administration & dosage | Practice Guidelines as Topic | Stroke (Disease) | Care and treatment | Usage | Atrial fibrillation | Diagnosis | Thrombolytic drugs | Patients | Health aspects | Risk factors | Arrhythmias and Sudden Death | 1506 | Stroke
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3. Full Text Two-year outcomes of patients with newly diagnosed atrial fibrillation: results from GARFIELD-AF
by Bassand, Jean-Pierre and Accetta, Gabriele and Camm, Alan John and Cools, Frank and Fitzmaurice, David A and Fox, Keith A. A and Goldhaber, Samuel Z and Goto, Shinya and Haas, Sylvia and Hacke, Werner and Kayani, Gloria and Mantovani, Lorenzo G and Misselwitz, Frank and ten Cate, Hugo and Turpie, Alexander G. G and Verheugt, Freek W. A and Kakkar, Ajay K and GARFIELD-AF Investigators
European Heart Journal, ISSN 0195-668X, 10/2016, Volume 37, Issue 38, pp. 2882 - 2889A
The relationship between outcomes and time after diagnosis for patients with non-valvular atrial fibrillation (NVAF) is poorly defined, especially beyond the... 
Stroke prevention | Stroke | Anticoagulation | Atrial fibrillation | Bleeding | MORTALITY | CARDIAC & CARDIOVASCULAR SYSTEMS | HEART-FAILURE | PREVENTION | DEATH | PREVALENCE | RISK STRATIFICATION SCHEMES | ANTITHROMBOTIC TREATMENT | RHYTHM MANAGEMENT | REGISTRY | Clinical Research
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4. Full Text Low-frequency drug-resistant HIV-1 and risk of virological failure to first-line NNRTI-based ART : A multicohort European case-control study using centralized ultrasensitive 454 pyrosequencing
by Cozzi-Lepri, Alessano and Noguera-Julian, Marc and Di Giallonardo, Francesca and Schuurman, Rob and Däumer, Martin and Aitken, Sue and Ceccherini-Silberstein, Francesca and Monforte, Antonella D Arminio and Geretti, Anna Maria and Booth, Clare L and Kaiser, Rolf and Michalik, Claudia and Jansen, Klaus and Masquelier, Bernard and Bellecave, Pantxika and Kouyos, Roger D and Castro, Erika and Furrer, Hansjakob and Schultze, Anna and Günthard, Hulych F and Brun-Vezinet, Francoise and Paredes, Roger and Metzner, Karin J and Brockmeyer, Norbert H and CHAIN Minority HIV-1 Variants and on behalf of the CHAIN Minority HIV-1 Variants Working Group
Journal of Antimicrobial Chemotherapy, ISSN 0305-7453, 03/2015, Volume 70, Issue 3, pp. 930 - 940
Objectives: It is still debated if pre-existing minority drug-resistant HIV-1 variants (MVs) affect the virological outcomes of first-line NNRTI-containing... 
CHAIN | Minority drug-resistant HIV-1 variants | Pharmacology (medical) | European multicentre study | Infectious Diseases | Pharmacology | Antiretroviral therapy | INFECTIOUS DISEASES | VARIANTS | antiretroviral therapy | REVERSE-TRANSCRIPTASE | MICROBIOLOGY | NEVIRAPINE | BASIC CONCEPTS | THERAPY | POLYMORPHISMS | minority drug-resistant HIV-1 variants | EFAVIRENZ | IMMUNODEFICIENCY-VIRUS TYPE-1 | PHARMACOLOGY & PHARMACY | MUTATIONS | ANTIRETROVIRAL TREATMENT | Original Research
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5. Full Text Combination Antiretroviral Therapy and the Risk of Myocardial Infarction: The Data Collection on Adverse Events of Anti-HIV Drugs (DAD) Study Group
by Friis-Møller, Nina and Sabin, Caroline A and Weber, Rainer and d'Arminio Monforte, Antonella and El-Sadr, Wafaa M and Reiss, Peter and Thiébaut, Rodolphe and Morfeldt, Linda and De Wit, Stephane and Pradier, Christian and Calvo, Gonzalo and Law, Matthew G and Kirk, Ole and Phillips, Andrew N and Lundgren, Jens D and Bartsch, G and Dabis, F and Houyez, F and Loeliger, E and Tressler, R and Weller, I and Sjøl, A and Sawitz, A and Rickenbach, M and Pezzotti, P and Krum, E and Meester, R and Lavignolle, V and Sundström, A and Poll, B and Fontas, E and Torres, F and Petoumenos, K and Kjær, J and Hammer, S and Neaton, J and Sjøl, A and de Wolf, F and van der Ven, E and Zaheri, S and Van Valkengoed, I and Bronsveld, W and Weigel, H and Brinkman, K and Frissen, P and ten Veen, J and Hillebrand, M and van Dam, P and Schieveld, S and Mulder, J and van Gorp, E and Meenhorst, P and van Eeden, A and Danner, S and Claessen, F and Perenboom, R and Eeftinck Schattenkerk, J.K and Godfried, M and Lange, J and Lowe, S and van der Meer, J and Nellen, F and Pogany, K and van der Poll, T and Prins, J and Ruys, T and van der Valk, M and Wit, F and Richter, C and van Leusen, R and Vriesendorp, R and Jeurissen, F and Kauffmann, R and Koger, E and Bravenboer, B and ten Napel, C and Sprenger, H.G and Law, G and ten Kate, R.W and Leemhuis, M and Kroon, F and Schippers, E and Schrey, G and van der Geest, S and Verbon, A and Koopmans, P and Keuter, M and Telgt, D and van der Ven, A and van der Ende, M and Gyssens, I and de Marie, S and Juttmann, J and van der Heul, C and Schneider, M and Borleffs, J and Hoepelman, I and Jaspers, C and Matute, A and Schurink, C and ...
New England Journal of Medicine, ISSN 0028-4793, 11/2003, Volume 349, Issue 21, pp. 1993 - 2003
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6. Full Text Combination Antiretroviral Therapy and the Risk of Myocardial Infarction
by Friis-Moller, N and Sabin, CA and Weber, R and Monforte, AD and El-Sa, WM and Reiss, P and Thiebaut, R and Morfeldt, L and De Wit, S and Pradier, C and Calvo, G and Law, MG and Kirk, O and Phillips, AN and Lundgren, JD and Monteforte, AD and Bartsch, G and Dabis, F and Houyez, F and Loeliger, E and Tressler, R and Weller, I and Sjol, A and Sawitz, A and Rickenbach, M and Pezzotti, P and Krum, E and Meester, R and Lavignolle, V and Mulder, J and van der Meer, J and Sprenger, HG and Koopmans, P and Borleffs, J and Crane, LR and Johnson, MA and Martinelli, C and The Data Collection on Adverse Events of Anti-HIV Drugs (DAD) Study Group and DAD Study Grp and Data Collection on Adverse Events of Anti-HIV Drugs (DAD) Study Group
The New England Journal of Medicine, ISSN 0028-4793, 11/2003, Volume 349, Issue 21, pp. 1993 - 2003
This prospective, observational study assessed the risk of myocardial infarction among 23,468 HIV-1–infected patients in relation to treatment with combination... 
MONICA PROJECT | HEART-DISEASE | ADULTS | LIPODYSTROPHY | HIV-1-INFECTED PATIENTS | EVENT RATES | ASSOCIATION | UMCG Approved | CORONARY-ARTERY-DISEASE | PROTEASE INHIBITORS | HIV-INFECTED PATIENTS | MEDICINE, GENERAL & INTERNAL | HIV-1 | Myocardial Infarction - chemically induced | Anti-Retroviral Agents - therapeutic use | Myocardial Infarction - epidemiology | Prospective Studies | Follow-Up Studies | Humans | Middle Aged | Risk Factors | Anti-Retroviral Agents - adverse effects | Male | CD4 Lymphocyte Count | Incidence | Regression Analysis | HIV Infections - complications | Adult | Female | HIV Infections - drug therapy | Poisson Distribution | Drug Therapy, Combination | Adverse and side effects | Antiviral agents | Anti-HIV agents | Heart attack | Risk factors | Clinical trials | Therapy | Heart attacks | Metabolism | Human immunodeficiency virus--HIV | Older people
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7. Full Text Development and validation of a risk score for chronic kidney disease in HIV infection using prospective cohort data from the D:A:D study
by Mocroft, Amanda and Lundgren, Jens D and Ross, Michael and Law, Matthew and Reiss, Peter and Kirk, Ole and Smith, Colette and Wentworth, Deborah and Neuhaus, Jacqueline and Fux, Christoph A and Moranne, Olivier and Morlat, Phillipe and Johnson, Margaret A and Ryom, Lene and Lundgren, J. D and Powderly, B and Shortman, N and Moecklinghoff, C and Reilly, G and Franquet, X and Sabin, C. A and Prins, J. M and Kuijpers, T. W and Scherpbier, H. J and van der Meer, J. T. M and Wit, F. W. M. N and Godfried, M. H and van der Poll, T and Nellen, F. J. B and Geerlings, S. E and van Vugt, M and Pajkrt, D and Bos, J. C and Wiersinga, W. J and van der Valk, M and Goorhuis, A and Hovius, J. W and Jurriaans, S and Back, N. K. T and Zaaijer, H. L and Berkhout, B and Cornelissen, M. T. E and Schinkel, C. J and Stelma, F. F and Langebeek, N and Vandenbroucke-Grauls, C. M. J. E and Grijsen, M and Lange, J and van der Horst, C and Frank, M and Royal Free Hosp Clin Cohort and INSIGHT Study Grp and DAD Study Grp and SMART Study Grp and ESPRIT Study Grp and D:A:D study group and Royal Free Hospital Clinic Cohort and SMART study group and INSIGHT study group and ESPRIT study group and D:A:D study group, the Royal Free Hospital Clinic Cohort, and the INSIGHT, SMART, and ESPRIT study groups
PLoS medicine, ISSN 1549-1277, 2015, Volume 12, Issue 3, pp. e1001809 - e1001809
Chronic kidney disease (CKD) is a major health issue for HIV-positive individuals, associated with increased morbidity and mortality. Development and... 
INDIVIDUALS | GLOMERULAR-FILTRATION-RATE | MEDICINE, GENERAL & INTERNAL | POSITIVE PERSONS | PROTEINURIA | ANTIRETROVIRAL THERAPY | ASSOCIATION | STAGE RENAL-DISEASE | LIFE EXPECTANCY | EXPOSURE | PREDICTION | Kidney - drug effects | Prospective Studies | Age Factors | Kidney - pathology | Renal Insufficiency, Chronic - etiology | Risk Assessment | Comorbidity | HIV Seropositivity - complications | Anti-HIV Agents - adverse effects | Humans | Middle Aged | Male | Risk | CD4 Lymphocyte Count | Incidence | Renal Insufficiency, Chronic - epidemiology | HIV | Clinical Decision-Making | HIV Infections - complications | Sex Factors | Adult | Anti-HIV Agents - therapeutic use | Female | HIV Infections - drug therapy | Index Medicus | Life Sciences | Human health and pathology | Santé publique et épidémiologie | Infectious diseases | Urology and Nephrology | Hypertension | Antiretroviral drugs | Mortality | Cardiovascular disease | Infections | Studies | Hepatitis | Data collection | Human immunodeficiency virus | Diabetes | Kidney diseases | Drug use
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