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Nature chemical biology, ISSN 1552-4450, 12/2014, Volume 10, Issue 12, pp. 1006 - 1012
Her3 (also known as ErbB3) belongs to the epidermal growth factor receptor tyrosine kinases and is well credentialed as an anti-cancer target but is thought to... 
ADJUVANT CHEMOTHERAPY | LUNG-CANCER | DOMAIN | PROTEIN | MET AMPLIFICATION | TYROSINE KINASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | SELECTIVE INHIBITORS | EXTENDED 5-SUBSTITUENT | OVARIAN-CANCER | HER2-POSITIVE BREAST-CANCER | Proto-Oncogene Proteins c-met - metabolism | Adenine - chemical synthesis | Receptor, ErbB-2 - genetics | Antineoplastic Agents - chemical synthesis | Humans | Protein Multimerization | Receptor, ErbB-2 - chemistry | Gene Expression Regulation, Neoplastic | Receptor, ErbB-2 - metabolism | Molecular Targeted Therapy | Receptor, ErbB-3 - chemistry | Proteolysis | Adenosine Triphosphate - metabolism | Antineoplastic Agents - pharmacology | Acrylamides - pharmacology | Protein Kinase Inhibitors - chemical synthesis | Catalytic Domain | Adenine - analogs & derivatives | Signal Transduction | Receptor, ErbB-3 - antagonists & inhibitors | Adenine - pharmacology | Cysteine - chemistry | Receptor, ErbB-3 - genetics | Proto-Oncogene Proteins c-met - genetics | Cell Line, Tumor | Hydrophobic and Hydrophilic Interactions | Cell Proliferation - drug effects | Molecular Docking Simulation | Protein Kinase Inhibitors - pharmacology | Adamantane - chemistry | Proto-Oncogene Proteins c-met - chemistry | Adenosine Triphosphate - chemistry | Acrylamides - chemical synthesis | Signal transduction | Cell growth | Phosphorylation | Pharmacology | Epidermal growth factor | Kinases
Journal Article
Cancer Research, ISSN 0008-5472, 04/2010, Volume 70, Issue 8 Supplement, pp. 362 - 362
Journal Article
The EMBO Journal, ISSN 0261-4189, 01/2018, Volume 37, Issue 1, pp. 19 - 38
The innate immune kinase TBK1 initiates inflammatory responses to combat infectious pathogens by driving production of type I interferons. TBK1 also controls... 
mTOR | IFN‐β | TBK1 | mTORC1 | IFN-β | IFN-beta | MAMMALIAN TARGET | BIOCHEMISTRY & MOLECULAR BIOLOGY | SIGNAL INTEGRATION | CELL-GROWTH | TRANSLATIONAL CONTROL | CELL BIOLOGY | SUBSTRATE-SPECIFICITY | MEDIATED ACTIVATION | INTERFERON REGULATORY FACTOR-3 | BREAST-CANCER ONCOGENE | S6 KINASE | ANTIVIRAL IMMUNITY | Immunity, Innate - drug effects | TOR Serine-Threonine Kinases - metabolism | Humans | Cells, Cultured | Protein-Serine-Threonine Kinases - genetics | Interferon Regulatory Factor-3 - genetics | Mechanistic Target of Rapamycin Complex 1 - metabolism | Protein Transport | Macrophages - metabolism | Mechanistic Target of Rapamycin Complex 1 - genetics | Animals | Cell Nucleus - metabolism | TOR Serine-Threonine Kinases - genetics | Signal Transduction - drug effects | Intercellular Signaling Peptides and Proteins - pharmacology | Interferon Regulatory Factor-3 - metabolism | Cytosol - metabolism | Macrophages - drug effects | Mice | Phosphorylation - drug effects | Macrophages - immunology | Protein-Serine-Threonine Kinases - metabolism | TOR protein | Cell proliferation | Phosphorylation | Innate immunity | Genomes | Activation | Catalytic activity | Macrophages | Immunity | Receptors | Cell activation | Cell growth | Epidermal growth factor | Toll-like receptors | Tumorigenesis | Catalysis | Growth factors | Translocation | Pathogens | Immune response | Cell survival | Rapamycin | Inflammation | TLR4 protein | Growth factor receptors | Gene expression | Insulin | Survival | Nuclear transport | TLR3 protein | Signaling | Interferon regulatory factor 3 | Interferon | Cancer | Immunology | Signal Transduction
Journal Article
PLoS ONE, ISSN 1932-6203, 08/2012, Volume 7, Issue 8, p. e43580
Journal Article
Journal Article
The Journal of Neuroscience, ISSN 0270-6474, 06/2017, Volume 37, Issue 24, p. 5870
Parkinson's disease (PD) patients progressively accumulate intracytoplasmic inclusions formed by misfolded α-synuclein known as Lewy bodies (LBs). LBs also... 
Cell culture | Parkinson's disease | Neurodegenerative diseases | Pathogenesis | Inclusions | Kinases | Synuclein | Lewy bodies | Proteins | Pathology | Autopsy | Proteomics | Affinity | Movement disorders
Journal Article
American Journal of Hypertension, ISSN 0895-7061, 8/2015, Volume 28, Issue 8, pp. 995 - 1009
Journal Article