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1. Full Text IL-35-producing B cells are critical regulators of immunity during autoimmune and infectious diseases
by Shen, Ping and Roch, Toralf and Lampropoulou, Vicky and O'Connor, Richard A and Stervbo, Ulrik and Hilgenberg, Ellen and Ries, Stefanie and Dang, Van Duc and Jaimes, Yarúa and Daridon, Capucine and Li, Rui and Jouneau, Luc and Boudinot, Pierre and Wilantri, Siska and Sakwa, Imme and Miyazaki, Yusei and Leech, Melanie D and McPherson, Rhoanne C and Wirtz, Stefan and Neurath, Markus and Hoehlig, Kai and Meinl, Edgar and Grützkau, Andreas and Grün, Joachim R and Horn, Katharina and Kühl, Anja A and Dörner, Thomas and Bar-Or, Amit and Kaufmann, Stefan H. E and Anderton, Stephen M and Fillatreau, Simon
Nature, ISSN 0028-0836, 2014, Volume 507, Issue 7492, pp. 366 - 370
B lymphocytes have critical roles as positive and negative regulators of immunity. Their inhibitory function has been associated primarily with interleukin 10... 
ACTIVATION | RITUXIMAB | MULTIDISCIPLINARY SCIENCES | ULCERATIVE-COLITIS | SALMONELLA-TYPHIMURIUM | PREVENTION | DEPLETION | CYTOKINE | ARTHRITIS | EXPRESSION | T-CELLS | Humans | Salmonella Infections - immunology | Encephalomyelitis, Autoimmune, Experimental - immunology | Male | Interleukins - metabolism | B-Lymphocytes - secretion | Interleukins - immunology | Interleukin-10 - metabolism | Female | Plasma Cells - metabolism | B-Lymphocytes - metabolism | Macrophages - immunology | Antigen-Presenting Cells - metabolism | Lymphocyte Activation | Immunity - immunology | Toll-Like Receptor 4 - immunology | Macrophages - cytology | Antigen-Presenting Cells - immunology | Animals | B-Lymphocytes - immunology | Salmonella Infections - microbiology | T-Lymphocytes - immunology | Mice | CD40 Antigens - immunology | Interleukins - secretion | Plasma Cells - immunology | Prevention | Control | Immune response | Interleukin-10 | B cells | Autoimmune diseases | Health aspects | Immunity | Immunological research | Inflammatory bowel disease | Antigens | Plasma | Salmonella | Disease | Cytokines | Pathogenesis | Lymphocytes | Immune system
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2. Full Text The Liver-Stage Plasmodium Infection Is a Critical Checkpoint for Development of Experimental Cerebral Malaria
by Sato, Yuko and Ries, Stefanie and Stenzel, Werner and Fillatreau, Simon and Matuschewski, Kai
Frontiers in Immunology, ISSN 1664-3224, 11/2019, Volume 10
Cerebral malaria is a life-threatening complication of malaria in humans, and the underlying pathogenic mechanisms are widely analyzed in a murine model of... 
Plasmodium | Genetic engineering | Research | Malaria | Risk factors | liver-stage | pre-erythrocytic stage | malaria | cerebral malaria | experimental cerebral malaria
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3. Full Text LAG-3 Inhibitory Receptor Expression Identifies Immunosuppressive Natural Regulatory Plasma Cells
by Lino, Andreia C and Dang, Van Duc and Lampropoulou, Vicky and Welle, Anna and Joedicke, Jara and Pohar, Jelka and Simon, Quentin and Thalmensi, Jessie and Baures, Aurelia and Flühler, Vinciane and Sakwa, Imme and Stervbo, Ulrik and Ries, Stefanie and Jouneau, Luc and Boudinot, Pierre and Tsubata, Takeshi and Adachi, Takahiro and Hutloff, Andreas and Dörner, Thomas and Zimber-Strobl, Ursula and de Vos, Alex F and Dahlke, Katja and Loh, Gunnar and Korniotis, Sarantis and Goosmann, Christian and Weill, Jean-Claude and Reynaud, Claude-Agnès and Kaufmann, Stefan H.E and Walter, Jörn and Fillatreau, Simon
Immunity, ISSN 1074-7613, 07/2018, Volume 49, Issue 1, pp. 120 - 133.e9
B lymphocytes can suppress immunity through interleukin (IL)-10 production in infectious, autoimmune, and malignant diseases. Here, we have identified a... 
BCR | infection | CD72 | LAG-3 | natural regulatory plasma cell | B cells | TLR | plasma cells | checkpoint receptor | interleukin-10 | immune regulation | B-CELLS | IMMUNITY | AUTOIMMUNITY | GENE-EXPRESSION | GENERATION | MODEL | DIFFERENTIATION | IMMUNOLOGY | TRANSCRIPTION FACTOR | IL-10 | Antigens, CD - immunology | Gene Expression | Signal Transduction | Lymphocyte Activation | Epigenesis, Genetic | Vaccines - immunology | Male | Up-Regulation - genetics | Gene Expression Profiling | Receptors, Antigen, B-Cell - metabolism | Antigens, CD - genetics | Plasma Cells - physiology | Salmonella Infections, Animal - immunology | Animals | Interleukin-10 - genetics | B-Lymphocyte Subsets - immunology | Female | Interleukin-10 - biosynthesis | T-Lymphocytes - immunology | Mice | Toll-Like Receptors - metabolism | Plasma Cells - immunology | Epigenetic inheritance | Antigens | Interleukins | Microbiology | Genetic vectors | T cells | Methylation | Cells | Salmonella | Genes | Interleukin | Lymphocytes T | Infections | Genomes | CD223 antigen | B-cell receptor | Immunity | Receptors | Microbiota | CD200 antigen | Lymphocytes | Interleukin 1 | DNA methylation | Toll-like receptors | Deoxyribonucleic acid--DNA | Immunological memory | Immunoglobulins | Gene expression | Immunosuppression | Lymphocytes B | Morphology | PD-L1 protein | Interleukin 10 | Plasma cells | Regulation | Receptor mechanisms | Binding sites
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4. Full Text B-type suppression: A role played by "regulatory B cells" or "regulatory plasma cells"?
by Ries, Stefanie and Hilgenberg, Ellen and Lampropoulou, Vicky and Shen, Ping and Dang, Van Duc and Wilantri, Siska and Sakwa, Imme and Fillatreau, Simon
European Journal of Immunology, ISSN 0014-2980, 2014, Volume 44, Issue 5, pp. 1251 - 1257
B-cell depletion can improve disease in some patients with rheumatoid arthritis or multiple sclerosis, indicating the pathogenic contribution of B cells to... 
Infection | Plasma cells | Autoimmune disease | Regulation | B cells | Interleukin-10 | Humans | B-Lymphocytes, Regulatory - immunology | Immunity, Innate | Arthritis, Rheumatoid - pathology | B-Lymphocytes, Regulatory - pathology | Plasma Cells - pathology | Animals | Immunity, Humoral | Interleukin-10 - metabolism | Multiple Sclerosis - immunology | Multiple Sclerosis - pathology | Mice | Arthritis, Rheumatoid - immunology | Plasma Cells - immunology | Autoimmunity | Analysis | Lymphocyte receptors | Plasma
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5. Full Text Anti‐interleukin‐6 signalling therapy rebalances the disrupted cytokine production of B cells from patients with active rheumatoid arthritis
by Fleischer, Sarah and Ries, Stefanie and Shen, Ping and Lheritier, Alix and Cazals, Frédéric and Burmester, Gerd. R and Dörner, Thomas and Fillatreau, Simon
European Journal of Immunology, ISSN 0014-2980, 01/2018, Volume 48, Issue 1, pp. 194 - 203
Rheumatoid arthritis (RA) is associated with abnormal B cell‐functions implicating antibody‐dependent and ‐independent mechanisms. B cells have emerged as... 
Autoimmunity | BCR | B cells | Cytokines | Rheumatoid arthritis | AUTOANTIBODIES | APOPTOSIS | ACTIVATION | LIGAND TRAIL | ANTIBODY | ALPHA | IMMUNOLOGY | INTERLEUKIN-8 | INHIBITION | AUTOIMMUNE-DISEASES | INFLAMMATION | Chemokine CCL4 - biosynthesis | Interleukin-6 - antagonists & inhibitors | Nerve Growth Factor - biosynthesis | Interleukin-8 - biosynthesis | Humans | Chemokine CXCL1 - biosynthesis | Arthritis, Rheumatoid - pathology | B-Lymphocytes - immunology | TNF-Related Apoptosis-Inducing Ligand - biosynthesis | Arthritis, Rheumatoid - drug therapy | Antibodies, Monoclonal, Humanized - pharmacology | Arthritis, Rheumatoid - immunology | Interleukin-6 - metabolism | Medical research | Care and treatment | Antirheumatic agents | Interleukins | Analysis | Medicine, Experimental | Arthritis | Immunity | Lymphocyte receptors | Drugs | Therapy | Pathogenesis | Abnormalities | Interleukin | Medical services | Nerve growth factor | T cell receptors | B-cell receptor | Patients | Interleukin 6 | Signaling | Cell activation | Lymphocytes B | Bioinformatics | Computer Science | Computational Geometry
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6. Full Text From the regulatory functions of B cells to the identification of cytokine-producing plasma cell subsets
by Dang, Van Duc and Hilgenberg, Ellen and Ries, Stefanie and Shen, Ping and Fillatreau, Simon
Current Opinion in Immunology, ISSN 0952-7915, 2014, Volume 28, Issue 1, pp. 77 - 83
Highlights • Plasma cells can produce anti-inflammatory cytokines. • Plasma cells can produce pro-inflammatory cytokines. • Microbial products are major... 
Allergy and Immunology | FACTOR IRF4 | RESPONSES | IGA | ACTIVATION | DENDRITIC CELLS | TRANSCRIPTIONAL REPRESSOR BLIMP-1 | DIFFERENTIATION | IMMUNOLOGY | TRYPANOSOMA-CRUZI INFECTION | T-CELLS | IL-10 | B-Lymphocytes - cytology | Animals | B-Lymphocytes - immunology | Nitric Oxide Synthase Type II - immunology | Humans | Cell Differentiation | Cytokines - biosynthesis | Plasma Cells - cytology | Cytokines - immunology | Plasma Cells - immunology | Trypanosoma cruzi - immunology | Cytokines | B cells
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7. Full Text Replacement of oxytocin bolus administration by infusion: influences on postpartum outcome
by Löytved-Hardegg, Julia J and Löytved-Hardegg, Julia J and Brunner, Mirjam and Brunner, Mirjam and Ries, Jean-Jacques and Ries, Jean-Jacques and von Felten, Stefanie and von Felten, Stefanie and Heugel, Christina and Heugel, Christina and Lapaire, Olav and Lapaire, Olav and Voekt, Cora and Voekt, Cora and Hösli, Irene and Hösli, Irene
Archives of Gynecology and Obstetrics, ISSN 0932-0067, 6/2016, Volume 293, Issue 6, pp. 1219 - 1225
Postpartum haemorrhage (PPH) represents a leading cause of maternal morbidity and mortality. Giving oxytocin after birth reduces the risk for PPH. It has never... 
Human Genetics | Medicine & Public Health | Oxytocin | Gynecology | Obstetrics/Perinatology | Endocrinology | Post partum haemorrhage | Third stage of labour | ANESTHESIA | HEMORRHAGE | CESAREAN DELIVERY | PARTURITION | LABOR | DURATION | OBSTETRICS & GYNECOLOGY | Humans | Postpartum Period | Labor Stage, Third | Pregnancy | Oxytocin - administration & dosage | Placenta, Retained - epidemiology | Delivery, Obstetric | Obstetric Labor Complications - epidemiology | Postpartum Hemorrhage - epidemiology | Oxytocics - administration & dosage | Adult | Female | Retrospective Studies | Placenta, Retained - therapy | Pregnancy Outcome | Mortality | Placenta | Maternal-Fetal Medicine
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8. Full Text Activation of CD4+Foxp3+ regulatory T cells proceeds normally in the absence of B cells during EAE
by Hoehlig, Kai and Shen, Ping and Lampropoulou, Vicky and Roch, Toralf and Malissen, Bernard and O'Connor, Richard and Ries, Stefanie and Hilgenberg, Ellen and Anderton, Stephen M and Fillatreau, Simon
European Journal of Immunology, ISSN 0014-2980, 05/2012, Volume 42, Issue 5, pp. 1164 - 1173
B cells and regulatory T (Treg) cells can both facilitate remission from experimental auto immune encephalomyelitis (EAE), a disease of the central nervous... 
Autoimmunity | EAE | B cells | Regulatory T cells | NERVOUS-SYSTEM | INTEGRIN | EXPERIMENTAL ALLERGIC ENCEPHALOMYELITIS | IMMUNOLOGY | AUTOIMMUNE ENCEPHALOMYELITIS | REMITTING MULTIPLE-SCLEROSIS | NAIVE-LIKE | INFLAMMATION | LYMPHOPROLIFERATIVE DISORDER | MICE | EXPRESSION | Forkhead Transcription Factors - immunology | Severity of Illness Index | Acute Disease | Lymphocyte Activation - immunology | Animals | B-Lymphocytes - immunology | Encephalomyelitis, Autoimmune, Experimental - immunology | Mice | Adoptive Transfer | Lymphocyte Depletion | Chronic Disease | T-Lymphocytes, Regulatory - immunology | Rodents | T cell receptors
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9. Full Text Bacterial interactions with proteins and cells relevant to the development of life-threatening endocarditis studied by use of a quartz-crystal microbalance
by Krajewski, Stefanie and Rheinlaender, Johannes and Ries, Philip and Canjuga, Denis and Mack, Carmen and Scheideler, Lutz and Schäffer, Tilman E and Geis-Gerstorfer, Jürgen and Wendel, Hans-Peter and Rupp, Frank
Analytical and Bioanalytical Chemistry, ISSN 1618-2642, 5/2014, Volume 406, Issue 14, pp. 3395 - 3406
Implant-related infections are a major challenge in clinical routine because of severe complications, for example infective endocarditis (IE). The purpose of... 
Biochemistry, general | Plasma | Food Science | Quartz-crystal microbalance | Bacterial adhesion | Laboratory Medicine | Chemistry | Analytical Chemistry | Endocarditis | Characterization and Evaluation of Materials | Platelets | Saliva | Environmental Monitoring/Analysis | CHEMISTRY, ANALYTICAL | QCM-D | LIQUID | BIOCHEMICAL RESEARCH METHODS | PIEZOELECTRIC IMMUNOSENSOR | COLONIZATION | ADSORPTION | STREPTOCOCCI | ADHESION | FREQUENCY | BIOFILM FORMATION | SURFACES | Gold - chemistry | Viscosity | Platelet Adhesiveness | Microscopy, Electron, Scanning | Quartz Crystal Microbalance Techniques | Humans | Streptococcus gordonii | Elasticity | Acoustics | Platelet-Rich Plasma - metabolism | Bacterial Adhesion | Biofilms | Endocarditis - microbiology | Endocarditis - diagnosis | Blood Platelets - metabolism | Saliva - metabolism | Biosensing Techniques | Microscopy, Atomic Force | Saliva - microbiology | Atomic force microscopy | Usage | Quartz crystals | Health aspects | Analysis
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10. Full Text Interleukin-10-producing B cells and the regulation of immunity
by Hilgenberg, Ellen and Shen, Ping and Dang, Van Duc and Ries, Stefanie and Sakwa, Imme and Fillatreau, Simon
Current Topics in Microbiology and Immunology, ISSN 0070-217X, 2014, Volume 380, pp. 69 - 92
B cells are usually considered primarily for their unique capacity to produce antibodies after differentiation into plasma cells. In addition to their roles as... 
Animals | B-Lymphocytes - immunology | Humans | Inflammatory Bowel Diseases - immunology | Listeriosis - immunology | Salmonella Infections - immunology | Encephalomyelitis, Autoimmune, Experimental - immunology | Salmonella typhimurium | Interleukin-10 - physiology
Conference Proceeding
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11. Full Text Strategies for the design of hydrophilic matrix tablets with controlled microenvironmental pH
by Siepe, Stefanie and Lueckel, Barbara and Kramer, Andrea and Ries, Angelika and Gurny, Robert
International Journal of Pharmaceutics, ISSN 0378-5173, 2006, Volume 316, Issue 1, pp. 14 - 20
Incorporation of weak acids as pH modifiers enhances the release of weakly basic drugs in higher pH environments by reducing the microenvironmental pH (pH ).... 
Weakly basic drug | Microenvironmental pH | pH modifier | Dipyridamole | HPMC | basic drug | dipyridamole | PROFILE | KETOCONAZOLE | INDEPENDENT RELEASE | CITRIC-ACID | PHARMACOLOGY & PHARMACY | microenvironmental pH | GASTRIC-ACIDITY | ABSORPTION | Kinetics | Tablets, Enteric-Coated - chemistry | Drug Design | Solubility | Hydrogen-Ion Concentration | Phosphates | Fumaric acid | Hydrogen-ion concentration | Analysis
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12. Full Text B‐type suppression: A role played by “regulatory B cells” or “regulatory plasma cells”?
by Ries, Stefanie and Hilgenberg, Ellen and Lampropoulou, Vicky and Shen, Ping and Dang, Van Duc and Wilantri, Siska and Sakwa, Imme and Fillatreau, Simon
European Journal of Immunology, ISSN 0014-2980, 05/2014, Volume 44, Issue 5, pp. 1251 - 1257
B‐cell depletion can improve disease in some patients with rheumatoid arthritis or multiple sclerosis, indicating the pathogenic contribution of B cells to... 
Infection | Plasma cells | Autoimmune disease | Regulation | B cells | Interleukin‐10
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13. Full Text B-type suppression: A role played by “regulatory B cells” or “regulatory plasma cells”?
: HIGHLIGHTS
by Ries, Stefanie and Hilgenberg, Ellen and Lampropoulou, Vicky and Shen, Ping and Dang, Van Duc and Wilantri, Siska and Sakwa, Imme and Fillatreau, Simon
European Journal of Immunology, ISSN 0014-2980, 05/2014, Volume 44, Issue 5, pp. 1251 - 1257
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14. Functional interactions between B lymphocytes and the innate immune system
by Lampropoulou, Vicky and Shen, Ping and Hilgenberg, Ellen and Ries, Stefanie and Opitz, Christian and Fillatreau, Simon
Infectious Disorders - Drug Targets, ISSN 1871-5265, 06/2012, Volume 12, Issue 3, pp. 191 - 199
Autoimmunity | Cytokines | Neutrophils | Infections | B cells | Humoral immunity | Innate cells
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15. Bacterial interactions with proteins and cells relevant to the development of life-threatening endocarditis studied by use of a quartz-crystal microbalance
by Krajewski, Stefanie and Rheinlaender, Johannes and Ries, Philip and Canjuga, Denis and Mack, Carmen and Scheideler, Lutz and Schaffer, Tilman E and Geis-Gerstorfer, Jurgen and Wendel, Hans-Peter and Rupp, Frank
Analytical and Bioanalytical Chemistry, ISSN 1618-2642, 05/2014, Volume 406, Issue 14, pp. 3395 - 3406
Implant-related infections are a major challenge in clinical routine because of severe complications, for example infective endocarditis (IE). The purpose of... 
Proteins | Scanning electron microscopy | Microbalances | Bacteria | Formations | Sensors | Saliva | Adhesion
Journal Article
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16. Full Text The GTPase activity of murine guanylate-binding protein 2 (mGBP2) controls the intracellular localization and recruitment to the parasitophorous vacuole of Toxoplasma gondii
by Kravets, Elisabeth and Degrandi, Daniel and Weidtkamp-Peters, Stefanie and Ries, Britta and Konermann, Carolin and Felekyan, Suren and Dargazanli, Julia M and Praefcke, Gerrit J. K and Seidel, Claus A. M and Schmitt, Lutz and Smits, Sander H. J and Pfeffer, Klaus
Journal of Biological Chemistry, ISSN 0021-9258, 08/2012, Volume 287, Issue 33, pp. 27452 - 27466
One of the most abundantly IFN-gamma-induced protein families different cell types is the 65-kDa guanylate-binding protein family that is recruited to the... 
DYNAMIN SUPERFAMILY | CLATHRIN-MEDIATED ENDOCYTOSIS | INTERFERON-GAMMA | P47 GTPASES | IFN-GAMMA | BIOCHEMISTRY & MOLECULAR BIOLOGY | FLUORESCENCE ANISOTROPY | ANTIVIRAL ACTIVITY | NUCLEOTIDE-BINDING | ENDOPLASMIC-RETICULUM | IMMUNITY-RELATED GTPASE | Guanosine Monophosphate - genetics | Vacuoles - enzymology | Toxoplasmosis - immunology | Protein Multimerization | Toxoplasmosis - enzymology | Interferon-gamma - metabolism | GTP-Binding Proteins - genetics | Vacuoles - immunology | Guanosine Diphosphate - metabolism | Guanosine Monophosphate - immunology | Interferon-gamma - genetics | Microscopy, Fluorescence, Multiphoton | Vacuoles - parasitology | Protein Structure, Tertiary | Vacuoles - genetics | GTP-Binding Proteins - immunology | Immunity, Innate | Toxoplasma | Animals | Guanosine Monophosphate - metabolism | Interferon-gamma - immunology | Toxoplasmosis - genetics | Mice | Guanosine Diphosphate - genetics | Guanosine Diphosphate - immunology | GTP-Binding Proteins - metabolism | Host-Pathogen Interactions | Parasitophorous Vacuole | Immunology | Toxoplasma gondii | Parasite | Interferon | Interferon-γ-inducible Guanylate-binding Proteins | GTPase
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