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Plant Physiology, ISSN 0032-0889, 4/2014, Volume 164, Issue 4, pp. 2167 - 2183
Siderophores are specific ferric iron chelators synthesized by virtually all microorganisms in response to iron deficiency. We have previously shown that they... 
Siderophores | Leaves | Up regulation | Genes | Plant roots | Homeostasis | Iron | SIGNALING AND RESPONSE | Plants | Gene expression | Immunity | Genes, Plant | Zinc - metabolism | Arabidopsis - immunology | Plant Roots - genetics | Pseudomonas syringae - drug effects | Plant Diseases - microbiology | Gene Expression Profiling | Water - pharmacology | Plant Roots - drug effects | Arabidopsis Proteins - metabolism | Time Factors | Cation Transport Proteins - metabolism | Cation Transport Proteins - genetics | Plant Immunity - drug effects | Plant Leaves - drug effects | Enterobacteriaceae - physiology | Homeostasis - drug effects | Phosphorylation - drug effects | Pseudomonas syringae - physiology | Deferoxamine - pharmacology | Arabidopsis Proteins - genetics | Arabidopsis - drug effects | Immunity, Innate - drug effects | Up-Regulation - genetics | Iron - metabolism | Siderophores - pharmacology | Arabidopsis - genetics | Up-Regulation - drug effects | Arabidopsis - microbiology | Gene Expression Regulation, Plant - drug effects | Iron Chelating Agents - pharmacology | Plant Leaves - genetics | Models, Biological | Homeostasis - genetics | Arabidopsis thaliana | Botanical research | Plant defenses | Diseases and pests | Nutritional aspects | Genetic research | Genetic aspects | Iron in the body | Genetic transcription | Research | Health aspects | Life Sciences
Journal Article
Genome Biology, ISSN 1474-7596, 08/2018, Volume 19, Issue 1, pp. 112 - 18
Journal Article
Frontiers in Neural Circuits, ISSN 1662-5110, 04/2016, Volume 10, p. 31
Mutation of the metabotropic glutamate receptor type 7 (mGlu7) induces absence-like epileptic seizures, but its precise role in the somatosensory... 
Short-term plasticity | Glutamate | EEG | Epilepsy | Thalamic network | Benzoxazoles - pharmacology | Membrane Potentials - genetics | Humans | Synaptic Potentials - drug effects | Channelrhodopsins | Receptors, Metabotropic Glutamate - metabolism | Cerebral Cortex - cytology | Excitatory Postsynaptic Potentials - drug effects | Neural Pathways - physiology | Post-Synaptic Density - genetics | Receptors, Metabotropic Glutamate - genetics | Thalamus - physiology | Excitatory Amino Acid Agents - pharmacology | HEK293 Cells | Neurons - physiology | Post-Synaptic Density - drug effects | GTP-Binding Protein alpha Subunits, Gq-G11 - metabolism | Neurons - drug effects | Excitatory Postsynaptic Potentials - genetics | Membrane Potentials - drug effects | GTP-Binding Protein alpha Subunits, Gq-G11 - genetics | Synaptic Potentials - genetics | Mice, Transgenic | Mutation - genetics | GABA Agents - pharmacology | Animals | Benzoxazoles - chemistry | Receptors, GABA-A - physiology | Cerebral Cortex - physiology | Mice | In Vitro Techniques | Metabotropic glutamate receptors | Neural transmission | Research | Gene mutations | Analysis | Neurosciences | Oscillations | Optics | Glutamic acid receptors | Mental depression | Proteins | Plasticity (behavioral) | Convulsions & seizures | γ-Aminobutyric acid | Allosteric properties | Synaptic transmission | Genetics | Thalamus | Physiology | Seizures | Firing pattern | Cortex | Mammals | Information processing | Ligands | Mutation | Glutamatergic transmission | Glutamic acid receptors (metabotropic) | Neurotransmission | thalamic network | short-term plasticity
Journal Article
FASEB Journal, ISSN 0892-6638, 04/2012, Volume 26, Issue 4, pp. 1682 - 1693
Metabotropic glutamate (mGlu) receptors are promising targets to treat numerous brain disorders. So far, allosteric modulators are the only subtype selective... 
Drug development | mGluR | Parkinson's disease | POSITIVE ALLOSTERIC MODULATION | SITE | ACTIVATION | ACID | RECOGNITION | DOCKING | BIOCHEMISTRY & MOLECULAR BIOLOGY | drug development | BINDING DOMAIN | MOLECULAR DETERMINANTS | CELL BIOLOGY | MGLUR4 | BIOLOGY | CHARMM | Antiparkinson Agents - pharmacology | Rats, Wistar | Humans | Male | Structure-Activity Relationship | Dose-Response Relationship, Drug | Receptors, Metabotropic Glutamate - genetics | HEK293 Cells | Antiparkinson Agents - chemistry | Synaptic Transmission - drug effects | Molecular Structure | Receptors, Metabotropic Glutamate - chemistry | Binding Sites | Recombinant Proteins - metabolism | Excitatory Amino Acid Agonists - metabolism | Mutagenesis, Site-Directed | Phosphinic Acids - chemistry | Rats | Excitatory Amino Acid Agonists - pharmacology | Recombinant Proteins - genetics | Mice, Knockout | Patch-Clamp Techniques | Animals | Phosphinic Acids - pharmacology | Phosphinic Acids - metabolism | Ligands | Mice | Receptors, Metabotropic Glutamate - agonists | Antiparkinson Agents - metabolism | Excitatory Amino Acid Agonists - chemistry | Excitatory Amino Acid Agonists | Neurons and Cognition | Neurobiology | Recombinant Proteins | Synaptic Transmission | Life Sciences | Phosphinic Acids | Psychology and behavior | Antiparkinson Agents | Receptors, Metabotropic Glutamate | Cognitive Sciences
Journal Article
PLANT PHYSIOLOGY, ISSN 0032-0889, 04/2014, Volume 164, Issue 4, pp. 2167 - 2183
Siderophores are specific ferric iron chelators synthesized by virtually all microorganisms in response to iron deficiency. We have previously shown that they... 
ARABIDOPSIS-THALIANA | SIGNALING PATHWAYS | OXIDATIVE STRESS | ERWINIA-CHRYSANTHEMI INFECTION | ORGANELLE BIOGENESIS | GLYCINE-RICH PROTEIN | METAL TRANSPORTER | FLUORESCENT PSEUDOMONAS | INDUCED SYSTEMIC RESISTANCE | INTESTINAL EPITHELIAL-CELLS | PLANT SCIENCES
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 01/2018, Volume 61, Issue 5, pp. 1969 - 1989
A group III metabotropic glutamate (mGlu) receptor agonist (PCEP) was identified by virtual HTS. This orthosteric ligand is composed by an l-AP4-derived... 
Life Sciences | Neurons and Cognition
Journal Article
Journal Article
Organic & biomolecular chemistry, 01/2015, Volume 13, Issue 4, pp. 1106 - 1112
A series of phosphinic glutamate derivatives (e.g.LSP1-2111) have been proven to be potent agonists of metabotropic glutamate (mGlu) receptors and shown... 
Index Medicus
Journal Article
ACS Chemical Neuroscience, ISSN 1948-7193, 09/2014, Volume 5, Issue 12, pp. 1221 - 1237
Metabotropic glutamate receptor 7 (mGlu7) is a member of the group III mGlu receptors (mGlus), encompassed by mGlu4, mGlu6, mGlu7, and mGlu8. mGlu7 is highly... 
Electrophysiology | Allosteric modulator | Hippocampus | Metabotropic glutamate receptor | CHEMISTRY, MEDICINAL | hippocampus | metabotropic glutamate receptor | AMYGDALA PLASTICITY | BIOCHEMISTRY & MOLECULAR BIOLOGY | NEUROSCIENCES | PROBE-DEPENDENCE | CHROMOSOME 3 | PHARMACOLOGICAL MODULATION | RODENT MODELS | LU AF21934 | electrophysiology | IN-VIVO | L-DOPA | AGONIST AMN082 | PARKINSONS-DISEASE | Propionates - pharmacology | Glycine - analogs & derivatives | Cricetulus | Calcium - metabolism | Humans | Male | Receptors, Metabotropic Glutamate - metabolism | Structure-Activity Relationship | Thallium - metabolism | Hippocampus - drug effects | Excitatory Postsynaptic Potentials - drug effects | Excitatory Amino Acid Agents - chemistry | Dose-Response Relationship, Drug | Transfection | Receptors, Metabotropic Glutamate - genetics | Excitatory Amino Acid Agents - pharmacology | HEK293 Cells | G Protein-Coupled Inwardly-Rectifying Potassium Channels - metabolism | Picolinic Acids - chemistry | CHO Cells | Picolinic Acids - pharmacology | Acetanilides - pharmacology | Glutamic Acid - pharmacology | Mice, Inbred C57BL | Rats | G Protein-Coupled Inwardly-Rectifying Potassium Channels - genetics | Hippocampus - metabolism | Pyrroles - pharmacology | Animals | Glycine - pharmacology | Acetanilides - chemistry | Benzoates - pharmacology | Pyrroles - chemistry | In Vitro Techniques
Journal Article
Nature, ISSN 0028-0836, 09/1995, Volume 377, Issue 6547, pp. 175 - 183
A yeast artificial chromosome library containing 33,000 clones with an average insert size of one megabase of human genomic DNA was extensively analysed by... 
SEQUENCES | CLONING | DNA | MULTIDISCIPLINARY SCIENCES | GENES | LIBRARY | POLYMERASE CHAIN-REACTION | YEAST ARTIFICIAL CHROMOSOMES | VECTORS | REPEATS | CLONES | Nucleic Acid Hybridization | Chromosomes, Artificial, Yeast | DNA Fingerprinting | Chromosome Mapping - methods | Humans | In Situ Hybridization, Fluorescence | Genetic Markers | Genome, Human | Sequence Tagged Sites
Journal Article
Applied Microbiology and Biotechnology, ISSN 0175-7598, 1993, Volume 38, Issue 6, pp. 755 - 762
The effect of the overexpression of the bioABFCD operon on the biotin biosynthetic pathway was investigated in an Escherichia coli K12 bioR mutant with a... 
PERFORMANCE LIQUID-CHROMATOGRAPHY | DETHIOBIOTIN | VERSATILE CLONING | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | PRODUCT | PURIFICATION | BACILLUS-SPHAERICUS | UVRB-GENE | OPERON | VECTORS | NUCLEOTIDE-SEQUENCE
Journal Article
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