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PLoS ONE, ISSN 1932-6203, 04/2013, Volume 8, Issue 4, p. e60447
This study addresses the molecular mechanisms underlying the action of subthalamic nucleus high frequency stimulation (STN-HFS) in the treatment of Parkinson's... 
DOPA-INDUCED DYSKINESIA | DOPAMINERGIC DENERVATED RATS | LEVODOPA-INDUCED DYSKINESIA | RETINOIC ACID | MESSENGER-RNA EXPRESSION | BASAL GANGLIA | MULTIDISCIPLINARY SCIENCES | GENE-EXPRESSION | SUBVENTRICULAR ZONE | DEEP BRAIN-STIMULATION | KINASE-C-DELTA | Levodopa - pharmacology | Electric Stimulation | Rats | Gene Expression Profiling | Parkinson Disease - genetics | Subthalamic Nucleus - metabolism | Corpus Striatum - metabolism | Gene Expression Regulation - drug effects | Metabolic Networks and Pathways - genetics | Animals | Deep Brain Stimulation | Behavior, Animal - drug effects | Parkinson Disease - metabolism | Cluster Analysis | Denervation | Disease Models, Animal | Complications and side effects | Care and treatment | Parkinson's disease | Physiological aspects | Genetic aspects | Dosage and administration | Research | Dopa | Gene expression | Neuroprotection | Basal ganglia | Genes | Gene regulation | Parkinsons disease | Solitary tract nucleus | Stimulation | Glutamic acid receptors | Kinases | Immunity | Neurogenesis | Nuclei | Coverings | Synaptic transmission | Rodents | Surgery | Down-regulation | Neostriatum | Levodopa | Movement disorders | Dyskinesia | Dopamine receptors | Dihydroxyphenylalanine | Dopamine | Cell survival | Neurodegenerative diseases | Medical treatment | Central nervous system diseases | High frequencies | Substrates | Biological activity | Electrical stimuli | Studies | Side effects | Thyroid-stimulating hormone | DNA microarrays | Molecular modelling | Laboratory animals | Glutamic acid receptors (metabotropic) | Apoptosis | Life Sciences | Cellular Biology
Journal Article
Nature Medicine, ISSN 1078-8956, 2011, Volume 17, Issue 6, pp. 700 - 707
The natural killer (NK) cell receptor NKp30 is involved in the recognition of tumor and dendritic cells (DCs). Here we describe the influence of three NKp30... 
MEDICINE, RESEARCH & EXPERIMENTAL | NATURAL-KILLER-CELLS | HUMAN DENDRITIC CELLS | BIOCHEMISTRY & MOLECULAR BIOLOGY | IL-10 PRODUCTION | C-KIT | TRIGGERING RECEPTOR | CELL BIOLOGY | NK CELLS | CLASS-III | CYTOTOXICITY RECEPTORS | HUMAN MHC | EXPRESSION | Prognosis | Alternative Splicing - genetics | Humans | Interleukin-12 - physiology | Lysosomal-Associated Membrane Protein 1 - physiology | Interferon-gamma - physiology | Alternative Splicing - physiology | Gastrointestinal Stromal Tumors - physiopathology | Natural Cytotoxicity Triggering Receptor 3 - genetics | Natural Cytotoxicity Triggering Receptor 3 - physiology | Killer Cells, Natural - physiology | Proto-Oncogene Proteins c-kit - physiology | Gastrointestinal Stromal Tumors - diagnosis | Protein Isoforms | Tumor Necrosis Factor-alpha - physiology | Cell Line, Tumor | Polymorphism, Single Nucleotide - genetics | Proto-Oncogene Proteins c-kit - genetics | Gastrointestinal Stromal Tumors - genetics | Dendritic cells | Gastrointestinal tumors | Physiological aspects | Genetic aspects | Research | Gene expression | Interferon | Medical prognosis | Gastrointestinal diseases | Tumors | Cancer | Interferon-gamma | Killer Cells, Natural | Alternative Splicing | Natural Cytotoxicity Triggering Receptor 3 | Interleukin-12 | Proto-Oncogene Proteins c-kit | Tumor Necrosis Factor-alpha | Life Sciences | Lysosomal-Associated Membrane Protein 1 | Immunology | Polymorphism, Single Nucleotide | Gastrointestinal Stromal Tumors
Journal Article
Nucleic Acids Research, ISSN 0305-1048, 08/2019, Volume 47, Issue 14, pp. e79 - e79
Abstract Genome-wide association studies (GWAS) associate single nucleotide polymorphisms (SNPs) to complex phenotypes. Most human SNPs fall in non-coding... 
PATHOGENICITY | VARIANTS | CHROMATIN | DATABASE | INTEGRATIVE ANALYSIS | HYPOPARATHYROIDISM | BIOCHEMISTRY & MOLECULAR BIOLOGY | PRIORITIZATION | IDENTIFICATION | ENHANCERS | BINDING | Life Sciences | Genetics | Quantitative Methods | Human genetics | Methods Online
Journal Article
Methods in molecular biology (Clifton, N.J.), ISSN 1064-3745, 2008, Volume 415, pp. 17 - 48
The identification of genes underlying complex traits is a challenging task, and there are a limited number of confirmed genes that influence human complex... 
Amino Acid Sequence | Genetic Predisposition to Disease | Base Sequence | Humans | Immunity, Innate - genetics | Databases, Genetic | Molecular Sequence Data | Polymorphism, Single Nucleotide - genetics | Family | Models, Genetic
Journal Article
Malaria Journal, ISSN 1475-2875, 2012, Volume 11, Issue 1, pp. 308 - 308
Journal Article
Journal Article
PLoS Genetics, ISSN 1553-7390, 07/2018, Volume 14, Issue 7, p. e1007502
Left ventricular non-compaction (LVNC) is a rare cardiomyopathy associated with a hypertrabeculated phenotype and a large spectrum of symptoms. It is still... 
CONTRACTION DEFECTS | CONDUCTION SYSTEM | NEUROMUSCULAR DISORDERS | CONGENITAL HEART-DISEASE | MOUSE MODEL | MUTATION | GENETICS & HEREDITY | GENE-EXPRESSION | MICE | NONCOMPACTION CARDIOMYOPATHY | PURKINJE-FIBER NETWORK | Sequence Deletion | Up-Regulation | Isolated Noncompaction of the Ventricular Myocardium - genetics | Homeodomain Proteins - metabolism | Humans | Isolated Noncompaction of the Ventricular Myocardium - complications | Heart Ventricles - embryology | Homeobox Protein Nkx-2.5 - metabolism | Gene Expression Profiling | Isolated Noncompaction of the Ventricular Myocardium - pathology | Gene Expression Regulation, Developmental | Myocardium - metabolism | Female | Homeobox Protein Nkx-2.5 - genetics | Heart Ventricles - pathology | Disease Models, Animal | Severity of Illness Index | Morphogenesis - genetics | Heart Failure - genetics | Myocardium - pathology | Mice, Knockout | Purkinje Fibers - pathology | Animals | Fibrosis | Mice | Isolated Noncompaction of the Ventricular Myocardium - diagnosis | Development and progression | Genetic aspects | Cardiomyopathy | Heart diseases | Heart ventricle, Left | Heart | Conduction | Transcription factors | Nuclear magnetic resonance--NMR | Funding | Compaction | Morphogenesis | Clonal deletion | Etiology | Supervision | Nkx2.5 protein | Heart failure | Hypoplasia | Phenotypes | Fetuses | Cardiomyocytes | Conditional mutant | Gene expression | Embryos | Pathogenicity | Myocardium | Mutation | Ventricle | Life Sciences | Human health and pathology | Cardiology and cardiovascular system | Nuclear magnetic resonance | NMR
Journal Article
PLoS ONE, ISSN 1932-6203, 12/2013, Volume 8, Issue 12, p. e81874
Synchrotron Microbeam Radiation Therapy (MRT) relies on the spatial fractionation of the synchrotron photon beam into parallel micro-beams applying several... 
MOUSE-BRAIN | DENDRITIC CELLS | GLIOSARCOMA | MULTIDISCIPLINARY SCIENCES | IN-VIVO | HUMAN TH17 CELLS | CENTRAL-NERVOUS-SYSTEM | GROWTH-FACTOR | X-RAY MICROBEAMS | IONIZING-RADIATION | INFILTRATION | Oligonucleotide Array Sequence Analysis | Rats, Inbred F344 | Immunity, Innate - genetics | Male | Gene Expression Profiling | Glioma - radiotherapy | Adaptive Immunity - genetics | Glioma - genetics | Signal Transduction - immunology | Brain Neoplasms - immunology | Synchrotrons | Signal Transduction - radiation effects | Brain Neoplasms - radiotherapy | Genes, MHC Class II - radiation effects | Brain Neoplasms - genetics | Glioma - immunology | Rats | Brain - radiation effects | Gene Expression - radiation effects | Adaptive Immunity - radiation effects | Animals | Radiotherapy - methods | Cell Line, Tumor | Immunity, Innate - radiation effects | Brain - immunology | Dendritic cells | Gliomas | Genes | Brain tumors | Radiation | B cells | Radiotherapy | Gene expression | Health aspects | Brain | Microbeams | Genomics | Brain cancer | Helper cells | Spatial discrimination | Irradiated | Nervous system | Lymphocytes T | Macrophages | Immunity | HMGB1 protein | Cancer therapies | Lymphokines | Proteins | Receptors | Immunology | Pathways | Lymphocytes | Rodents | Animal tissues | Toll-like receptors | Natural killer cells | Growth factors | Immune system | Fractionation | Immune response | Cytokines | Immunomodulation | Photon beams | Committees | Inflammation | Radiation therapy | CD36 antigen | Glioma | Lymphocytes B | Lectins | Irradiation | Tumors | Life Sciences | Neurons and Cognition
Journal Article
BMC MEDICAL GENOMICS, ISSN 1755-8794, 10/2019, Volume 12, Issue 1, pp. 148 - 15
Journal Article
Journal Article