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1. Full Text Association studies of up to 1.2 million individuals yield new insights into the genetic etiology of tobacco and alcohol use
by Liu, Mengzhen and Jiang, Yu and Wedow, Robbee and Li, Yue and Brazel, David M and Chen, Fang and Datta, Gargi and Davila-Velderrain, Jose and McGuire, Daniel and Tian, Chao and Zhan, Xiaowei and Agee, Michelle and Alipanahi, Babak and Auton, Adam and Bell, Robert K and Bryc, Katarzyna and Elson, Sarah L and Fontanillas, Pierre and Furlotte, Nicholas A and Hinds, David A and Hromatka, Bethann S and Huber, Karen E and Kleinman, Aaron and Litterman, Nadia K and McIntyre, Matthew H and Mountain, Joanna L and Northover, Carrie A. M and Sathirapongsasuti, J. Fah and Sazonova, Olga V and Shelton, Janie F and Shringarpure, Suyash and Tung, Joyce Y and Vacic, Vladimir and Wilson, Catherine H and Pitts, Steven J and Mitchell, Amy and Skogholt, Anne Heidi and Winsvold, Bendik Slagsvold and Sivertsen, Børge and Stordal, Eystein and Morken, Gunnar and Kallestad, Håvard and Heuch, Ingrid and Zwart, John-Anker and Fjukstad, Katrine Kveli and Pedersen, Linda M and Gabrielsen, Maiken Elvestad and Johnsen, Marianne Bakke and Skrove, Marit and Indredavik, Marit Sæbø and Drange, Ole Kristian and Bjerkeset, Ottar and Børte, Sigrid and Stensland, Synne Øien and Choquet, Hélène and Docherty, Anna R and Faul, Jessica D and Foerster, Johanna R and Fritsche, Lars G and Gordon, Scott D and Haessler, Jeffrey and Hottenga, Jouke-Jan and Huang, Hongyan and Jang, Seon-Kyeong and Jansen, Philip R and Ling, Yueh and Mägi, Reedik and Matoba, Nana and McMahon, George and Mulas, Antonella and Orrù, Valeria and Palviainen, Teemu and Pandit, Anita and Reginsson, Gunnar W and Smith, Jennifer A and Taylor, Amy E and Turman, Constance and Willemsen, Gonneke and Young, Hannah and Young, Kendra A and Zajac, Gregory J. M and Zhao, Wei and Zhou, Wei and Bjornsdottir, Gyda and Boardman, Jason D and Boehnke, Michael and Boomsma, Dorret I and Chen, Chu and Cucca, Francesco and Davies, Gareth E and Eaton, Charles B and Ehringer, Marissa A and Esko, Tõnu and Fiorillo, Edoardo and Gillespie, Nathan A and Gudbjartsson, Daniel F and Haller, Toomas and Harris, Kathleen Mullan and Heath, Andrew C and Hewitt, John K and ... and HUNT All In Psychiat and 23 Me Res Team and 23andMe Research Team and HUNT All-In Psychiatry
Nature genetics, ISSN 1061-4036, 02/2019, Volume 51, Issue 2, pp. 237 - 244
Genetics | Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Phenotype | Humans | Middle Aged | Female | Male | Risk | Smoking - genetics | Tobacco Use Disorder - genetics | Genetic Variation - genetics | Tobacco - adverse effects | Genome-Wide Association Study - methods | Alcohol Drinking - genetics | Usage | Analysis | Influence | Drinking of alcoholic beverages | Research | Health aspects | Causes and theories of causation | Risk factors | Diseases | Tobacco habit | Phenotypes | Dopamine | Genes | Health risks | Principal components analysis | Nervous system | Genomes | Loci | Alcohol use | Datasets | Substance use | Studies | Genetic variance | Signal transduction | Tobacco | Etiology | Alcoholic beverages | Glutamatergic transmission | Health risk assessment | Neurotransmission | Drug use | Dopamine receptors | Smoking | Index Medicus
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2. Full Text Genome-wide meta-analysis identifies six novel loci associated with habitual coffee consumption
by Cornelis, M. C and Byrne, E. M and Esko, T and Nalls, M. A and Ganna, A and Paynter, N and Monda, K. L and Amin, N and Fischer, K and Renstrom, F and Ngwa, J. S and Huikari, V and Cavadino, A and Nolte, I. M and Teumer, A and Yu, K and Marques-Vidal, P and Rawal, R and Manichaikul, A and Wojczynski, M. K and Vink, J. M and Zhao, J. H and Burlutsky, G and Lahti, J and Mikkilä, V and Lemaitre, R. N and Eriksson, J and Musani, S. K and Tanaka, T and Geller, F and Luan, J and Hui, J and Mägi, R and Dimitriou, M and Garcia, M. E and Ho, W.-K and Wright, M. J and Rose, L. M and Magnusson, P. K. E and Pedersen, N. L and Couper, D and Oostra, B. A and Hofman, A and Ikram, M. A and Tiemeier, H. W and Uitterlinden, A. G and van Rooij, F. J. A and Barroso, I and Int Parkinson's Dis Genomics Conso and North Amer Brain Expression Consor and UK Brain Expression Consortium and Coffee & Caffeine Genetics Consort and North American Brain Expression Consortium (NABEC) and UK Brain Expression Consortium (UKBEC) and Coffee and Caffeine Genetics Consortium and International Parkinson’s Disease Genomics Consortium (IPDGC) and International Parkinson's Disease Genomics Consortium (IPDGC) and The Coffee and Caffeine Genetics Consortium and Institutionen för medicin, avdelningen för samhällsmedicin och folkhälsa and Göteborgs universitet and Gothenburg University and Institutionen för medicin, avdelningen för invärtesmedicin och klinisk nutrition and Institute of Medicine, School of Public Health and Community Medicine and Sahlgrenska Academy and Centre for Bone and Arthritis Research and Sahlgrenska akademin and Institute of Medicine, Department of Internal Medicine and Clinical Nutrition
Molecular psychiatry, ISSN 1359-4184, 2015, Volume 20, Issue 5, pp. 647 - 656
Biochemistry & Molecular Biology | Neurosciences | Neurosciences & Neurology | Life Sciences & Biomedicine | Psychiatry | Science & Technology | Coffea - metabolism | Brain-Derived Neurotrophic Factor - genetics | Genome-Wide Association Study | Phenotype | Cytochrome P-450 CYP1A2 - genetics | Humans | Adaptor Proteins, Signal Transducing - genetics | Basic Helix-Loop-Helix Leucine Zipper Transcription Factors - genetics | Polymorphism, Single Nucleotide - genetics | Feeding Behavior | Type 2 diabetes | Usage | Care and treatment | Parkinson's disease | Genomes | Research | Coffee | Health aspects | Risk factors | Meta-analysis | Adipose tissue | Genes | Consumers | Lipids | Single-nucleotide polymorphism | Nucleotides | Cost-benefit analysis | Blood pressure | Beverages | Caffeine | Consumption | Pharmacodynamics | Cytochrome P450 | Health risks | Pharmacology | Inflammation | CYP1A2 protein | Insulin | Loci | Ethnic factors | Brain-derived neurotrophic factor | Molecular modelling | Diet | Cups | Alleles | Pharmacokinetics | Health risk assessment | Smoking | Index Medicus | Endokrinologi och diabetes | Endocrinology and Diabetes
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3. Full Text Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study
by Voight, Benjamin F, PhD and Peloso, Gina M, PhD and Orho-Melander, Marju, PhD and Frikke-Schmidt, Ruth, DMSc and Barbalic, Maja, PhD and Jensen, Majken K, PhD and Hindy, George, MD and Hólm, Hilma, MD and Ding, Eric L, ScD and Johnson, Toby, PhD and Schunkert, Heribert, Prof and Samani, Nilesh J, Prof and Clarke, Robert, MD and Hopewell, Jemma C, PhD and Thompson, John F, Prof and Li, Mingyao, PhD and Thorleifsson, Gudmar, PhD and Newton-Cheh, Christopher, MD and Musunuru, Kiran, MD and Pirruccello, James P, BS and Saleheen, Danish, MBBS and Chen, Li, MSc and Stewart, Alexandre FR, PhD and Schillert, Arne, PhD and Thorsteinsdottir, Unnur, PhD and Thorgeirsson, Gudmundur, MD and Anand, Sonia, Prof and Engert, James C, PhD and Morgan, Thomas, MD and Spertus, John, Prof and Stoll, Monika, Prof and Berger, Klaus, Prof and Martinelli, Nicola, MD and Girelli, Domenico, Prof and McKeown, Pascal P, Prof and Patterson, Christopher C, PhD and Epstein, Stephen E, MD and Devaney, Joseph, PhD and Burnett, Mary-Susan, PhD and Mooser, Vincent, MD and Ripatti, Samuli, PhD and Surakka, Ida, BSci and Nieminen, Markku S, Prof and Sinisalo, Juha, MD and Lokki, Marja-Liisa, PhD and Perola, Markus, Prof and Havulinna, Aki, PhD and de Faire, Ulf, Prof and Gigante, Bruna, MD and Ingelsson, Erik, PhD and Zeller, Tanja, PhD and Wild, Philipp, MD and de Bakker, Paul I W, Prof and Klungel, Olaf H, PhD and Maitland-van der Zee, Anke-Hilse, PhD and Peters, Bas J M, PhD and de Boer, Anthonius, Prof and Grobbee, Diederick E, Prof and Kamphuisen, Pieter W, PhD and Deneer, Vera H M, PhD and Elbers, Clara C, PhD and Onland-Moret, N Charlotte, PhD and Hofker, Marten H, Prof and Wijmenga, Cisca, Prof and Verschuren, WM Monique, PhD and Boer, Jolanda MA, PhD and van der Schouw, Yvonne T, Prof and Rasheed, Asif and Frossard, Philippe and Demissie, Serkalem, PhD and Willer, Cristen, PhD and Do, Ron, PhD and Ordovas, Jose M, Prof and Abecasis, Gonçalo R, Prof and Boehnke, Michael, Prof and Mohlke, Karen L, PhD and Daly, Mark J, PhD and Guiducci, Candace, BS and Burtt, Noël P, BS and Surti, Aarti, BS and Gonzalez, Elena, BS and Purcell, Shaun, PhD and Gabriel, Stacey, PhD and Marrugat, Jaume, PhD and Peden, John, PhD and Erdmann, Jeanette, PhD and Diemert, Patrick, MD and Willenborg, Christina, MSc and König, Inke R, PhD and Fischer, Marcus, MD and Hengstenberg, Christian, MD and Ziegler, Andreas, PhD and Buysschaert, Ian, MD and Lambrechts, Diether, PhD and Van de Werf, Frans, Prof and Fox, Keith A, Prof and El Mokhtari, Nour Eddine, MD and Rubin, Diana, MD and Schrezenmeir, Jürgen, PhD and Schreiber, Stefan, Prof and ...
The Lancet (British edition), ISSN 0140-6736, 08/2012, Volume 380, Issue 9841, pp. 572 - 580
Internal Medicine | ENDOTHELIAL LIPASE | METAANALYSIS | BLOOD CHOLESTEROL | ATHEROSCLEROSIS | GENETIC-VARIANTS | LOCI | CORONARY-HEART-DISEASE | UMCG Approved | HIGH-DENSITY-LIPOPROTEIN | ISCHEMIC CARDIOVASCULAR-DISEASE | ARTERY-DISEASE | Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | Cardiology. Vascular system | Heart | General aspects | Biological and medical sciences | Metabolic diseases | Medical sciences | Coronary heart disease | Disorders of blood lipids. Hyperlipoproteinemia | Mendelian Randomization Analysis - methods | Myocardial Infarction - blood | Myocardial Infarction - genetics | Genetic Predisposition to Disease | Myocardial Infarction - epidemiology | Prospective Studies | Gene Frequency | Humans | Risk Factors | Biomarkers - blood | Case-Control Studies | Cholesterol, HDL - blood | Cholesterol, LDL - blood | Polymorphism, Single Nucleotide | Myocardial Infarction - etiology | Lipase - genetics | Genetic aspects | High density lipoproteins | Health aspects | Heart attack | Risk factors | Studies | Plasma | Heart attacks | Diet | Cardiovascular disease | Lipids | Cholesterol | Index Medicus | Abridged Index Medicus | Kardiologi | Clinical Medicine | Cardiac and Cardiovascular Systems | Endokrinologi och diabetes | Medical and Health Sciences | Medicin och hälsovetenskap | Klinisk medicin | Endocrinology and Diabetes
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4. Full Text A Genome-Wide Association Study of Depressive Symptoms
by Hek, Karin and Demirkan, Ayse and Lahti, Jari and Terracciano, Antonio and Teumer, Alexander and Cornelis, Marilyn C and Amin, Najaf and Bakshis, Erin and Baumert, Jens and Ding, Jingzhong and Liu, Yongmei and Marciante, Kristin and Meirelles, Osorio and Nalls, Michael A and Sun, Yan V and Vogelzangs, Nicole and Yu, Lei and Bandinelli, Stefania and Benjamin, Emelia J and Bennett, David A and Boomsma, Dorret and Cannas, Alessandra and Coker, Laura H and de Geus, Eco and De Jager, Philip L and Diez-Roux, Ana V and Purcell, Shaun and Hu, Frank B and Rimm, Eric B and Hunter, David J and Jensen, Majken K and Curhan, Gary and Rice, Kenneth and Penman, Alan D and Rotter, Jerome I and Sotoodehnia, Nona and Emeny, Rebecca and Eriksson, Johan G and Evans, Denis A and Ferrucci, Luigi and Fornage, Myriam and Gudnason, Vilmundur and Hofman, Albert and Illig, Thomas and Kardia, Sharon and Kelly-Hayes, Margaret and Koenen, Karestan and Kraft, Peter and Kuningas, Maris and Massaro, Joseph M and Melzer, David and Mulas, Antonella and Mulder, Cornelis L and Murray, Anna and Oostra, Ben A and Palotie, Aarno and Penninx, Brenda and Petersmann, Astrid and Pilling, Luke C and Psaty, Bruce and Rawal, Rajesh and Reiman, Eric M and Schulz, Andrea and Shulman, Joshua M and Singleton, Andrew B and Smith, Albert V and Sutin, Angelina R and Uitterlinden, André G and Völzke, Henry and Widen, Elisabeth and Yaffe, Kristine and Zonderman, Alan B and Cucca, Francesco and Harris, Tamara and Ladwig, Karl-Heinz and Llewellyn, David J and Räikkönen, Katri and Tanaka, Toshiko and van Duijn, Cornelia M and Grabe, Hans J and Launer, Lenore J and Lunetta, Kathryn L and Mosley, Thomas H and Newman, Anne B and Tiemeier, Henning and Murabito, Joanne
Biological psychiatry (1969), ISSN 0006-3223, 04/2013, Volume 73, Issue 7, pp. 667 - 678
Psychiatry | genetics | genome-wide association study | meta-analysis | depression | depressive symptoms | Center for Epidemiologic Studies Depression Scale | CHARGE consortium | Neurosciences | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Psychology. Psychoanalysis. Psychiatry | Adult and adolescent clinical studies | Psychopathology. Psychiatry | Mood disorders | Biological and medical sciences | Depression | Medical sciences | Genetic Predisposition to Disease - genetics | Genome-Wide Association Study | Humans | Middle Aged | Aged, 80 and over | Polymorphism, Single Nucleotide - genetics | Female | Male | Aged | Depression - genetics | Chromosomes, Human, Pair 5 - genetics | Genetic research | Analysis | Depression, Mental | Genomics | Index Medicus
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5. Full Text Metabolic mediators of the effects of body-mass index, overweight, and obesity on coronary heart disease and stroke: a pooled analysis of 97 prospective cohorts with 1·8 million participants
by Lu, Yuan and Hajifathalian, Kaveh and Ezzati, Majid and Woodward, Mark and Rimm, Eric B and Danaei, Goodarz and Selmer, Randi and Strand, Bjorn H and Dobson, A and Hozawa, A and Nozaki, A and Okayama, Akira and Rodgers, A and Tamakoshi, A and Zhou, B.F and Zhou, B and Yao, C.H and Jiang, C.Q and Gu, D.F and Heng, D and Giles, Graham G and Shan, G.L and Whitlock, G and Arima, H and Kim, H.C and Christensen, H and Horibe, H and Maegawa, H and Tanaka, H and Ueshima, Hirotsugu and Zhang, H.Y and Kim, I.S and Suh, I and Fuh, J.L and Lee, J and Woo, Jean and Xie, J.X and Zhou, J and Hughes, K and Jamrozik, K and Nakachi, K and Sakata, K and Shimamoto, K and Chen, L.Q and Liu, L.S and Hobbs, M and Iida, M and Kagaya, M and Divitini, Mark L and Luszcz, M and Nakamura, M and Huang, M.S and Knuiman, Matthew W and Aoki, N and Norman, P and Sritara, P and Yang, Q.D and Broadhurst, R and Huxley, R and Jackson, R and Norton, R and Ameratunga, S and Ho, S.C and Li, S.C and Jee, S.H and Chew, S.K and Macmahon, S and Choudhury, S.R and Saitoh, S and Yao, S.X and Welborn, Timothy A and Lam, T.H and Hashimoto, T and Ohkubo, T and Pan, Wen-Harn and Duan, X.F and Fang, X and Wu, X.G and Fang, X.H and Yu, X.H and Li, Y.H and He, Y and Imai, Y and Kita, Y and Kiyohara, Yutaka and Matsutani, Y and Hong, Z and Wu, Z.L and Chen, Z.M and Wu, Z.S and Tang, Z and Li, Z.Z and Parker, Emily D and Pereira, Mark A and Stevens, June and Panagiotakos, Demosthenes B and Pitsavos, Christos and Attia, John R and D’este, Catherine A and Zhang, Xiaofei and ... and The Global Burden of Metabolic Risk Factors for Chronic Diseases Collaboration (BMI Mediated Effects) and Global Burden of Metabolic Risk Factors for Chronic Diseases Collaboration (BMI Mediated Effects)
The Lancet (British edition), ISSN 0140-6736, 2014, Volume 383, Issue 9921, pp. 970 - 983
Internal Medicine | Cardiology. Vascular system | Heart | Obesity | General aspects | Biological and medical sciences | Metabolic diseases | Medical sciences | Coronary heart disease | Body Mass Index | Coronary Disease - blood | Overweight - complications | Obesity - complications | Cholesterol - blood | Humans | Risk Factors | Coronary Disease - etiology | Coronary Disease - physiopathology | Obesity - physiopathology | Biomarkers - blood | Overweight - physiopathology | Obesity - blood | Stroke - physiopathology | Stroke - blood | Stroke - etiology | Overweight - blood | Blood Pressure - physiology | Blood Glucose - metabolism | Stroke (Disease) | Body mass index | Health aspects | Risk factors | Studies | Weight control | Heart attacks | Cardiovascular disease | Drug therapy | Cholesterol | Index Medicus | Abridged Index Medicus | Medicin och hälsovetenskap
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