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Nature Genetics, ISSN 1061-4036, 2012, Volume 44, Issue 2, pp. 133 - 139
Journal Article
PLoS ONE, ISSN 1932-6203, 02/2012, Volume 7, Issue 2, pp. e30852 - e30852
Journal Article
The American Journal of Human Genetics, ISSN 0002-9297, 11/2016, Volume 99, Issue 5, pp. 1190 - 1198
Uveal melanoma (UM) is a rare intraocular tumor that, similar to cutaneous melanoma, originates from melanocytes. To gain insights into its genetics, we... 
OCULAR MELANOMA | CELLS | COLORECTAL-CANCER | PROTEINS DLK1 | METASTASES | GENETICS & HEREDITY | RISK | EXPRESSION | RADIATION | SF3B1 | SOMATIC MUTATIONS | Melanoma - diagnosis | Exons | Humans | Middle Aged | Male | Phosphoproteins - metabolism | Case-Control Studies | RNA Splicing Factors - metabolism | DNA Copy Number Variations | Melanoma - genetics | Melanocytes - pathology | Tumor Suppressor Proteins - genetics | Aged, 80 and over | Ubiquitin Thiolesterase - metabolism | Adult | Female | Membrane Proteins - metabolism | Eukaryotic Initiation Factor-1 - metabolism | GTP-Binding Protein alpha Subunits, Gq-G11 - metabolism | Tumor Suppressor p53-Binding Protein 1 - metabolism | GTP-Binding Protein alpha Subunits, Gq-G11 - genetics | Uveal Neoplasms - genetics | Genome-Wide Association Study | Tumor Suppressor Proteins - metabolism | GTP-Binding Protein alpha Subunits - metabolism | Tumor Suppressor p53-Binding Protein 1 - genetics | Membrane Proteins - genetics | Eukaryotic Initiation Factor-1 - genetics | Ubiquitin-Protein Ligases - metabolism | GTP-Binding Protein alpha Subunits - genetics | Phosphoproteins - genetics | RNA Splicing Factors - genetics | Ubiquitin Thiolesterase - genetics | Skin Neoplasms | Uveal Neoplasms - diagnosis | Aged | Mutation | Ubiquitin-Protein Ligases - genetics | Genetic aspects | Nucleotide sequencing | Methods | Melanoma | DNA sequencing | Metastasis | Pathogenesis | Genomics | Deoxyribonucleic acid--DNA | Index Medicus | Report
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 2005, Volume 115, Issue 3, pp. 739 - 746
The induction of potent CD8+ T cell responses by vaccines to fight microbes or tumors remains a major challenge, as many candidates for human vaccines have... 
Index Medicus | Abridged Index Medicus
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 01/2010, Volume 120, Issue 1, pp. 157 - 167
The function of antigen-specific CD8(+) T cells, which may protect against both infectious and malignant diseases, can be impaired by ligation of their... 
MEDICINE, RESEARCH & EXPERIMENTAL | B-LYMPHOCYTE | ACTIVATION | HERPESVIRUS ENTRY MEDIATOR | IMMUNE-SYSTEM | LYMPHOCYTE ATTENUATOR | CHRONIC VIRAL-INFECTION | EXPRESSION | CANCER-THERAPY | CUTTING EDGE | ANTIGEN | Index Medicus | Abridged Index Medicus
Journal Article
PLoS ONE, ISSN 1932-6203, 2011, Volume 6, Issue 4, pp. e18369 - e18369
Cancer genomes frequently contain somatic copy number alterations (SCNA) that can significantly perturb the expression level of affected genes and thus disrupt... 
ARRAY CGH DATA | SIGNALING PATHWAYS | HUMAN BREAST | MULTIDISCIPLINARY SCIENCES | PROTEIN-COUPLED RECEPTORS | FIBROBLAST-GROWTH-FACTOR | MALIGNANT-MELANOMA | COMPARATIVE GENOMIC HYBRIDIZATION | CELL-LINES | CIRCULAR BINARY SEGMENTATION | HUMAN CANCER | Proto-Oncogene Proteins c-mdm2 - genetics | Gene Regulatory Networks - genetics | Humans | RNA, Messenger - genetics | Gene Expression Regulation, Neoplastic | Databases, Genetic | In Situ Hybridization, Fluorescence | DNA Copy Number Variations - genetics | Signal Transduction - genetics | Melanoma - pathology | RNA, Messenger - metabolism | Neoplasm Metastasis | Comparative Genomic Hybridization | Melanoma - genetics | Karyotyping | Cell Line, Tumor | Polymorphism, Single Nucleotide - genetics | Genes, Neoplasm - genetics | RNA | Analysis | Genes | Genomics | Melanoma | Genetic research | Cytogenetics | Genomes | Genetic aspects | Metastasis | Gene expression | Cancer | Provenance | Wnt protein | Copy number | Encyclopedias | Single-nucleotide polymorphism | Parameter identification | Experiments | Data bases | Metastases | Proteins | Angiogenesis | Signal transduction | Alterations | Pathways | Genetics | Tumorigenesis | Chromosomes | Bioinformatics | Microphthalmia-associated transcription factor | Medical research | Cadherin | Ribonucleic acid--RNA | Signaling | Acids | Data sets | Cell lines | Proteomics | Prostate cancer | PTEN protein | Index Medicus | Ribonucleic acid
Journal Article
Frontiers in Immunology, ISSN 1664-3224, 08/2016, Volume 7, pp. 326 - 326
While T cell-based immunotherapies are steadily improving, there are still many patients who progress, despite T cell-infiltrated tumors. Emerging evidence... 
NanoString | Co-culture | CD8+ T cell | Antigen-specific | Melanoma | antigen-specific | MECHANISM | VACCINATION | melanoma | SELF-ANTIGEN | IMMUNOLOGY | IDENTIFICATION | co-culture | CLONE | ANTIGEN-EXPRESSION | IN-VIVO | GENES | CD8+T cell | IPILIMUMAB | Cell interaction | Lymphocytes | Health aspects | Cancer cells
Journal Article
Nano Letters, ISSN 1530-6984, 09/2016, Volume 16, Issue 9, pp. 5373 - 5377
According to the American skin cancer foundation, there are mote new eases of skin cancer than the combined incidence of cancers of the breast prostate, lung,... 
skin cancer | biosensor | malignant melanoma | Nanomechanical microcantilever | CELLS | PHYSICS, CONDENSED MATTER | PHYSICS, APPLIED | ASSAY | RNA | MATERIALS SCIENCE, MULTIDISCIPLINARY | CHEMISTRY, PHYSICAL | NANOSCIENCE & NANOTECHNOLOGY | SENSORS | CANCER | CHEMISTRY, MULTIDISCIPLINARY | NANOMECHANICAL CANTILEVER ARRAY | DNA | VEMURAFENIB | Index Medicus
Journal Article
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, ISSN 0146-0404, 06/2019, Volume 60, Issue 7, pp. 2764 - 2772
PURPOSE. To analyze the activity of mitogen-activated protein kinase (MAPK) and phosphoinositide 3-kinases/mechanistic target of rapamycin (PI3K/mTOR) pathways... 
MAPK pathway | HARBOR BRAF | conjunctiva | COMBINED NIVOLUMAB | melanoma | IMPROVED SURVIVAL | BRAF | OPEN-LABEL | MALIGNANT-MELANOMA | NRAS MUTATIONS | CELL-LINES | PI3K INHIBITOR | mutations | UVEAL MELANOMA | BRAF MUTATIONS | OPHTHALMOLOGY
Journal Article