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MODERN PATHOLOGY, ISSN 0893-3952, 08/2019, Volume 32, Issue 8, pp. 1168 - 1179
The checkpoint molecule TIM-3 is a target for emerging immunotherapies and has been identified on a variety of malignancies. Mismatch repair-deficient... 
TUMOR-INFILTRATING LYMPHOCYTES | RESPONSES | GERMLINE | INSTABILITY | PD-1 BLOCKADE | DEATH | COLON | LYNCH SYNDROME | PATHOLOGY | UP-REGULATION | NIVOLUMAB PLUS IPILIMUMAB | Immunohistochemistry | MSH6 protein | Yeast | Carcinoma | Immune response | Immune checkpoint | Endometrial cancer | MLH1 protein | Mismatch repair | Immunotherapy | Endometrium | Tumors | Index Medicus
Journal Article
Human Pathology, ISSN 0046-8177, 12/2018, Volume 82, pp. 20 - 31
As multigene panel testing for hereditary cancer syndromes becomes commonplace, germline mutations in genes other than /2 are increasingly identified in breast... 
Breast carcinoma | Familial cancer | Breast cancer | Germline mutations | Non-BRCA mutations | Mutation | Health risk assessment | Womens health | Ovarian cancer
Journal Article
International Journal of Gynecological Pathology, ISSN 0277-1691, 06/2019, p. 1
LAG-3 is an immunosuppressive checkpoint molecule expressed on T cells. One of its ligands, GAL-3, can promote the progression of malignancy and has been... 
Journal Article
Gynecologic Oncology Reports, ISSN 2352-5789, 05/2019, Volume 28, pp. 18 - 22
The objectives of this study were to determine both surgical and subsequent cancer outcomes for high-risk women from the University of Virginia's High-Risk... 
BRCA | Serous tubal intraepithelial carcinoma | High-risk cancer | Risk-reducing surgery
Journal Article
The American Journal of Surgical Pathology, ISSN 0147-5185, 03/2017, Volume 41, Issue 3, pp. 326 - 333
Mismatch repair (MMR)-deficient endometrial carcinomas (ECs) bearing Lynch syndrome (LS)-associated germline mutations or sporadic MLH1 promoter... 
PD-L1 | mismatch repair | endometrial carcinoma | MLH1 hypermethylation | immunotherapy | Lynch syndrome | SURGERY | MICROSATELLITE INSTABILITY | INFILTRATING LYMPHOCYTES | IMMUNOSCORE | PATHOLOGY | LUNG-CANCER | PROGNOSTIC-FACTOR | IMMUNE-SYSTEM | MICROENVIRONMENT | COLORECTAL-CANCER | BLOCKADE | Immunohistochemistry | Neoplastic Syndromes, Hereditary - pathology | Prognosis | Follow-Up Studies | Endometrial Neoplasms - mortality | Colorectal Neoplasms - genetics | Colorectal Neoplasms, Hereditary Nonpolyposis - pathology | Humans | Middle Aged | Brain Neoplasms - pathology | Endometrial Neoplasms - metabolism | Gene Expression Regulation, Neoplastic | Neoplastic Syndromes, Hereditary - metabolism | Brain Neoplasms - metabolism | Neoplastic Syndromes, Hereditary - mortality | Colorectal Neoplasms, Hereditary Nonpolyposis - mortality | DNA Methylation | Endometrial Neoplasms - genetics | DNA Mismatch Repair | Biomarkers, Tumor - metabolism | Female | Neoplastic Syndromes, Hereditary - genetics | Brain Neoplasms - mortality | Colorectal Neoplasms - metabolism | Colorectal Neoplasms - mortality | Promoter Regions, Genetic | Colorectal Neoplasms, Hereditary Nonpolyposis - genetics | Brain Neoplasms - genetics | Colorectal Neoplasms, Hereditary Nonpolyposis - metabolism | B7-H1 Antigen - metabolism | MutL Protein Homolog 1 - genetics | Endometrial Neoplasms - pathology | Aged | Biomarkers, Tumor - genetics | Colorectal Neoplasms - pathology | Index Medicus
Journal Article
Human Pathology, ISSN 0046-8177, 12/2018, Volume 82, pp. 20 - 31
As multigene panel testing for hereditary cancer syndromes becomes commonplace, germline mutations in genes other than BRCA1/2 are increasingly identified in... 
Breast carcinoma | Familial cancer | Breast cancer | Germline mutations | Non-BRCA mutations | PANEL | HISTOPATHOLOGICAL FEATURES | SUSCEPTIBILITY | PATHOLOGY | CARRIERS | TUMORS | PALB2 | WOMEN | CANCER-RISK | EARLY-ONSET | SPECTRUM | Care and treatment | Genetic aspects | Gene mutations | Tumor proteins
Journal Article
Obstetrics & Gynecology, ISSN 0029-7844, 05/2018, Volume 131 Suppl 1, pp. 15S - 15S
INTRODUCTION:Up to 20% of ovarian cancers are attributed to inherited predispositions, however current screening methods (Ca-125 and pelvic ultrasound) do not... 
OBSTETRICS & GYNECOLOGY
Journal Article
Familial Cancer, ISSN 1389-9600, 07/2019, Volume 18, Issue 3, pp. 303 - 309
Journal Article
Journal of Genetic Counseling, ISSN 1059-7700, 06/2019, Volume 28, Issue 3, pp. 700 - 707
Journal Article