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BLOOD, ISSN 0006-4971, 10/2019, Volume 134, Issue 14, pp. 1113 - 1114
In this issue of Blood, Staber et al report the initial activities of the newly created T-cell prolymphocytic leukemia (T-PLL) International Study Group... 
HEMATOLOGY
Journal Article
Seminars in Hematology, ISSN 0037-1963, 07/2018, Volume 55, Issue 3, pp. 113 - 117
Journal Article
Blood, ISSN 0006-4971, 10/2014, Volume 124, Issue 18, pp. 2804 - 2811
Paroxysmal nocturnal hemoglobinuria (PNH) is a rarebone marrow failure disorder that manifests with hemolytic anemia, thrombosis, and peripheral blood... 
PIG-A GENE | COMPLEMENT INHIBITOR ECULIZUMAB | BONE-MARROW-TRANSPLANTATION | MUTANT-CELLS | INTRAVASCULAR HEMOLYSIS | LONG-TERM SAFETY | DECAY-ACCELERATING FACTOR | STEM-CELL TRANSPLANTATION | HEMATOLOGY | APLASTIC-ANEMIA | INTRACELLULAR TRAFFICKING
Journal Article
Advances in experimental medicine and biology, ISSN 0065-2598, 2013, Volume 735, pp. 155 - 172
Journal Article
Blood, ISSN 0006-4971, 11/2018, Volume 132, Issue Supplement 1, pp. 5711 - 5711
Abstract While vast majority of patients achieve robust engraftment within a few weeks after allogeneic hematopoietic stem cell transplantation (HSCT), some... 
Journal Article
Biology of Blood and Marrow Transplantation, ISSN 1083-8791, 09/2019, Volume 25, Issue 9, pp. e277 - e284
The improved success of HLA-matched unrelated donor (MUD) hematopoietic stem cell transplantation (HSCT) for severe aplastic anemia (SAA) in recent decades has... 
Severe aplastic anemia | Hematopoietic stem cell transplantation | Alemtuzumab | Usage | Adults | Eltrombopag | Antithymocyte globulin | Aplastic anemia
Journal Article
Blood, ISSN 0006-4971, 11/2019, Volume 134, Issue Supplement_1, pp. 2226 - 2226
Background: In PNH, a somatic mutation in the PIGA gene of one or a few hematopoietic stem cells generates a clone of abnormal erythrocytes which lack two key... 
Journal Article
Blood, ISSN 0006-4971, 11/2019, Volume 134, Issue Supplement_1, pp. 3514 - 3514
Background: PNH is a rare, acquired blood disorder. A somatic mutation in the PIGA gene of one or more hematopoietic stem cells generates a clone of abnormal... 
Journal Article
Blood, ISSN 0006-4971, 11/2019, Volume 134, Issue Supplement_1, pp. 3517 - 3517
Introduction Eculizumab (Ecu) is the standard treatment for paroxysmal nocturnal hemoglobinuria (PNH), as it results in sustained control of intravascular... 
Journal Article
Blood, ISSN 0006-4971, 12/2016, Volume 128, Issue 22, pp. 1505 - 1505
Abstract Aplastic anemia (AA), pure red cell aplasia (PRCA), pure white cell aplasia (PWCA), idiopathic neutropenia (IN) and T cell large granular lymphocytic... 
Journal Article
Blood, ISSN 0006-4971, 11/2018, Volume 132, Issue Supplement 1, pp. 626 - 626
Abstract Background/Objective: In 2 large, phase 3 clinical studies, ravulizumab (ALXN1210), an innovative C5 inhibitor administered every 8 weeks, achieved... 
Journal Article
Haematologica, ISSN 0390-6078, 04/2018, Volume 103, Issue 5, pp. 747 - 749
Journal Article
Haematologica, ISSN 0390-6078, 01/2020, p. haematol.2019.236877
Eculizumab is first-line treatment for paroxysmal nocturnal hemoglobinuria (PNH); however, approximately 11%-27% of patients may experience breakthrough... 
Journal Article
Blood, ISSN 0006-4971, 12/2016, Volume 128, Issue 22, pp. 401 - 401
Abstract C5-blockade with eculizumab prevents complement-mediated intravascular hemolysis in PNH patients and its clinical consequences. However, a distinct... 
Journal Article
British Journal of Haematology, ISSN 0007-1048, 09/2018, Volume 182, Issue 6, pp. 758 - 776
Journal Article
Blood, ISSN 0006-4971, 05/2017, Volume 129, Issue 21, pp. 2824 - 2826
In this issue of Blood, Zaimoku et al demonstrate that the functional loss of the HLA-B4002 allele is common in aplastic anemia (AA) patients, suggesting that... 
HEMATOLOGY | APLASTIC-ANEMIA | T-CELLS
Journal Article
Blood, ISSN 0006-4971, 12/2015, Volume 126, Issue 23, pp. 1208 - 1208
Abstract Fanconi anemia (FA) is a rare inherited syndrome characterized by chromosomal instability, eventually resulting in a number of manifestations... 
Journal Article
Blood, ISSN 0006-4971, 11/2018, Volume 132, Issue Supplement 1, pp. 625 - 625
Abstract Introduction Ravulizumab, an innovative complement C5 inhibitor given every 8 weeks (q8w), was recently demonstrated in a large phase 3 study of... 
Journal Article