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The New England Journal of Medicine, ISSN 0028-4793, 06/2015, Volume 372, Issue 25, pp. 2387 - 2397
In this trial, patients with an acute coronary syndrome within the previous 10 days were randomly assigned to simvastatin plus either ezetimibe or placebo. At... 
CHOLESTEROL ABSORPTION | CARDIAC OUTCOMES | MEDICINE, GENERAL & INTERNAL | MYOCARDIAL-INFARCTION | EFFICACY | CARDIOVASCULAR OUTCOMES | CLINICAL-TRIALS | SIMVASTATIN | PRIMARY PREVENTION | IMPROVE-IT | ATORVASTATIN | Simvastatin - therapeutic use | Double-Blind Method | Cardiovascular Diseases - prevention & control | Humans | Middle Aged | Azetidines - adverse effects | Ezetimibe | Kaplan-Meier Estimate | Male | Anticholesteremic Agents - adverse effects | Acute Coronary Syndrome - drug therapy | Anticholesteremic Agents - therapeutic use | Hydroxymethylglutaryl-CoA Reductase Inhibitors - adverse effects | Azetidines - therapeutic use | Hydroxymethylglutaryl-CoA Reductase Inhibitors - therapeutic use | Triglycerides - blood | Cardiovascular Diseases - epidemiology | Cardiovascular Diseases - mortality | Cholesterol, LDL - blood | Female | Aged | Drug Therapy, Combination | Usage | Simvastatin | Analysis | Practice guidelines (Medicine) | Dosage and administration | Drug therapy, Combination | Acute coronary syndrome | Drug therapy | Myocardial infarction | Cerebral infarction | Lipoproteins (low density) | Stroke | Angina | Cholesterol | Intestine | Gallbladder | Acute coronary syndromes | Cardiovascular diseases | Statins | Pharmaceuticals | Cancer | Life Sciences | Human health and pathology | Cardiology and cardiovascular system
Journal Article
Analytical Chemistry, ISSN 0003-2700, 06/2019, Volume 91, Issue 11, pp. 7403 - 7410
The apurinic/apyrimidinic (AP) site is a common lesion of DNA damage. The levels of AP sites reported in the literature cover a wide range, which is primarily... 
Oxidative stress | Hydroxylamine | Kidneys | DNA damage | Mass spectroscopy | Liquid chromatography | Nucleotides | Quantitation | DNA repair | Artifacts | Apyrimidinic sites | In vivo methods and tests | Mustard | Lesions | Mass spectrometry | Deoxyribonucleic acid--DNA
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 3/2010, Volume 107, Issue 11, pp. 4925 - 4930
To protect cells from oxidative DNA damage and mutagenesis, organisms possess multiple glycosylases to recognize the damaged bases and to initiate the Base... 
Proteins | Enzymes | Schiff bases | DNA | Escherichia coli | DNA damage | Biochemistry | Lesions | Genetic mutation | DNA repair | Endonuclease VIII like 3 | Spiroiminodihydantoin | Base excision repair | 2,6-diamino-4-hydroxy-5- formamidopyrimidine (FapyG) | BASE-EXCISION-REPAIR | PROTEIN | OXIDATIVELY DAMAGED DNA | RECOGNITION | 2,6-diamino-4-hydroxy-5-formamidopyrimidine (FapyG) | MULTIDISCIPLINARY SCIENCES | ESCHERICHIA-COLI | base excision repair | endonuclease VIII Like 3 | COLI ENDONUCLEASE-VIII | OXIDIZED BASES | LESIONS | FORMAMIDOPYRIMIDINES | EXPRESSION | Gamma Rays | DNA Glycosylases - chemistry | Molecular Sequence Data | Pyrimidines - metabolism | Endodeoxyribonucleases - metabolism | Guanidines - metabolism | Hydantoins - metabolism | DNA Glycosylases - metabolism | Guanosine - analogs & derivatives | Amino Acid Sequence | DNA - metabolism | Endodeoxyribonucleases - chemistry | Guanosine - metabolism | Mutation - genetics | Sequence Homology, Amino Acid | Sequence Alignment | Animals | Valine - metabolism | Escherichia coli - genetics | Substrate Specificity - radiation effects | Mice | Schiff Bases - metabolism | DNA Damage | Kinetics | Spiro Compounds - metabolism | Physiological aspects | Hydrolases | Genetic aspects | Research | Index Medicus | Nei protein | Mutagenesis | Proline | purines | DNA glycosylase | valine | Mutation | Nucleophiles | Biological Sciences
Journal Article
Chemical Research in Toxicology, ISSN 0893-228X, 05/2009, Volume 22, Issue 5, pp. 759 - 778
The α,β-unsaturated aldehydes (enals) acrolein, crotonaldehyde, and trans -4-hydroxynonenal (4-HNE) are products of endogenous lipid peroxidation, arising as a... 
Review
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 3/2016, Volume 113, Issue 11, pp. E1452 - E1459
Journal Article
Lancet Respiratory Medicine, The, ISSN 2213-2600, 2017, Volume 5, Issue 5, pp. 412 - 425
Journal Article