PLoS Pathogens, ISSN 1553-7366, 07/2011, Volume 7, Issue 7, p. e1002132
Closely related pathogens may differ dramatically in host range, but the molecular, genetic, and evolutionary basis for these differences remains unclear. In...
AVIRULENCE GENES | HOST-SPECIFICITY | MICROBIOLOGY | EFFECTOR REPERTOIRE | FUNCTIONAL SCREEN | PHASEOLICOLA 1448A | PLANT IMMUNITY | VIROLOGY | VIRULENCE EFFECTOR | PV. TOMATO DC3000 | PARASITOLOGY | III SECRETION SYSTEM | INNATE IMMUNITY | Biological Evolution | Genome, Bacterial | Virulence Factors - genetics | Base Sequence | Genomics | Alleles | Bacterial Proteins - genetics | Plasmids - genetics | Plant Diseases - genetics | Pseudomonas syringae - genetics | Phylogeny | Pseudomonas syringae - pathogenicity | Pseudomonas syringae | Research | Proteins | Medical research | Flowers & plants | Microbiology | Plasmids
AVIRULENCE GENES | HOST-SPECIFICITY | MICROBIOLOGY | EFFECTOR REPERTOIRE | FUNCTIONAL SCREEN | PHASEOLICOLA 1448A | PLANT IMMUNITY | VIROLOGY | VIRULENCE EFFECTOR | PV. TOMATO DC3000 | PARASITOLOGY | III SECRETION SYSTEM | INNATE IMMUNITY | Biological Evolution | Genome, Bacterial | Virulence Factors - genetics | Base Sequence | Genomics | Alleles | Bacterial Proteins - genetics | Plasmids - genetics | Plant Diseases - genetics | Pseudomonas syringae - genetics | Phylogeny | Pseudomonas syringae - pathogenicity | Pseudomonas syringae | Research | Proteins | Medical research | Flowers & plants | Microbiology | Plasmids
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 10/2014, Volume 111, Issue 43, pp. 15544 - 15549
Previous studies have established that a subset of head and neck tumors contains human papillomavirus (HPV) sequences and that HPV-driven head and neck cancers...
Head | Squamous cell carcinoma | Head and neck neoplasms | Genes | DNA | Genomes | Neck | Methylation | Tumors | Cancer | Head and neck | Papilloma virus | Genome rearrangement | Integration sites | CERVICAL CARCINOGENESIS | TRANSFORMATION | HUMAN-PAPILLOMAVIRUS TYPE-16 | MULTIDISCIPLINARY SCIENCES | KERATINOCYTES | integration sites | papilloma virus | INTEGRATION | genome rearrangement | OROPHARYNGEAL CANCER | PROSTATE-CANCER | SQUAMOUS-CELL CARCINOMA | head and neck | cancer | TUMORIGENESIS | Virus Integration - genetics | Head and Neck Neoplasms - virology | Host-Pathogen Interactions - genetics | Base Sequence | Genes, Neoplasm | Humans | Gene Expression Regulation, Neoplastic | Molecular Sequence Data | Head and Neck Neoplasms - genetics | DNA Methylation - genetics | Papillomaviridae - physiology | Genome, Human - genetics | Oncology, Experimental | Host-parasite relationships | Head and neck cancer | Development and progression | Genetic aspects | Research | Gene expression | Virus research | Papillomavirus infections | Biological Sciences
Head | Squamous cell carcinoma | Head and neck neoplasms | Genes | DNA | Genomes | Neck | Methylation | Tumors | Cancer | Head and neck | Papilloma virus | Genome rearrangement | Integration sites | CERVICAL CARCINOGENESIS | TRANSFORMATION | HUMAN-PAPILLOMAVIRUS TYPE-16 | MULTIDISCIPLINARY SCIENCES | KERATINOCYTES | integration sites | papilloma virus | INTEGRATION | genome rearrangement | OROPHARYNGEAL CANCER | PROSTATE-CANCER | SQUAMOUS-CELL CARCINOMA | head and neck | cancer | TUMORIGENESIS | Virus Integration - genetics | Head and Neck Neoplasms - virology | Host-Pathogen Interactions - genetics | Base Sequence | Genes, Neoplasm | Humans | Gene Expression Regulation, Neoplastic | Molecular Sequence Data | Head and Neck Neoplasms - genetics | DNA Methylation - genetics | Papillomaviridae - physiology | Genome, Human - genetics | Oncology, Experimental | Host-parasite relationships | Head and neck cancer | Development and progression | Genetic aspects | Research | Gene expression | Virus research | Papillomavirus infections | Biological Sciences
Journal Article
Nature, ISSN 0028-0836, 01/2015, Volume 517, Issue 7536, pp. 576 - 582
The Cancer Genome Atlas profiled 279 head and neck squamous cell carcinomas (HNSCCs) to provide a comprehensive landscape of somatic genomic alterations. Here...
CANCER GROWTH | ACTIVATION | GROWTH-FACTOR-RECEPTOR | MULTIDISCIPLINARY SCIENCES | RESISTANCE | CLASSIFICATION | INHIBITORS | MUTATIONS | NF-KAPPA-B | LIM PROTEIN AJUBA | EGFR | Oncogenes - genetics | Carcinoma, Squamous Cell - genetics | Genomics | Humans | Male | DNA Copy Number Variations - genetics | Signal Transduction - genetics | Molecular Targeted Therapy | Mutation - genetics | Genome, Human - genetics | Transcription Factors - metabolism | Squamous Cell Carcinoma of Head and Neck | RNA, Neoplasm - genetics | Female | Head and Neck Neoplasms - genetics | DNA, Neoplasm - genetics | Gene Expression Regulation, Neoplastic - genetics | Squamous cell carcinoma | Oncology, Experimental | Genetic research | Head and neck cancer | Genetic aspects | Research | Gene expression | Cancer | Transcription factors | Cell cycle | DNA methylation | Genomes | Mutation | Head & neck cancer | Kinases | Cancer therapies | Tumors | Apoptosis
CANCER GROWTH | ACTIVATION | GROWTH-FACTOR-RECEPTOR | MULTIDISCIPLINARY SCIENCES | RESISTANCE | CLASSIFICATION | INHIBITORS | MUTATIONS | NF-KAPPA-B | LIM PROTEIN AJUBA | EGFR | Oncogenes - genetics | Carcinoma, Squamous Cell - genetics | Genomics | Humans | Male | DNA Copy Number Variations - genetics | Signal Transduction - genetics | Molecular Targeted Therapy | Mutation - genetics | Genome, Human - genetics | Transcription Factors - metabolism | Squamous Cell Carcinoma of Head and Neck | RNA, Neoplasm - genetics | Female | Head and Neck Neoplasms - genetics | DNA, Neoplasm - genetics | Gene Expression Regulation, Neoplastic - genetics | Squamous cell carcinoma | Oncology, Experimental | Genetic research | Head and neck cancer | Genetic aspects | Research | Gene expression | Cancer | Transcription factors | Cell cycle | DNA methylation | Genomes | Mutation | Head & neck cancer | Kinases | Cancer therapies | Tumors | Apoptosis
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International Journal of Radiation Oncology, Biology, Physics, ISSN 0360-3016, 2017, Volume 98, Issue 2, pp. E41 - E42
Journal Article
Nature, ISSN 0028-0836, 09/2012, Volume 489, Issue 7414, pp. 75 - 82
DNase I hypersensitive sites (DHSs) are markers of regulatory DNA and have underpinned the discovery of all classes of cis-regulatory elements including...
LOCUS-CONTROL REGION | PROTEIN | MULTIDISCIPLINARY SCIENCES | TRANSCRIPTION | DISTINCT | NF-E2 | BINDING | BETA-GLOBIN LOCUS | Chromatin - metabolism | Genomics | Humans | Molecular Sequence Annotation | Mutation Rate | Promoter Regions, Genetic - genetics | Genome, Human - genetics | Regulatory Sequences, Nucleic Acid - genetics | Encyclopedias as Topic | DNA - genetics | DNA Footprinting | DNA-Binding Proteins - metabolism | Transcription Factors - metabolism | Deoxyribonuclease I - metabolism | DNA Methylation | Transcription Initiation Site | Transcription, Genetic | Chromatin - genetics | Evolution, Molecular | Physiological aspects | Genetic research | Chromatin | Research | Human genome | DNA | Proteins | DNA methylation | Mutation | Cells
LOCUS-CONTROL REGION | PROTEIN | MULTIDISCIPLINARY SCIENCES | TRANSCRIPTION | DISTINCT | NF-E2 | BINDING | BETA-GLOBIN LOCUS | Chromatin - metabolism | Genomics | Humans | Molecular Sequence Annotation | Mutation Rate | Promoter Regions, Genetic - genetics | Genome, Human - genetics | Regulatory Sequences, Nucleic Acid - genetics | Encyclopedias as Topic | DNA - genetics | DNA Footprinting | DNA-Binding Proteins - metabolism | Transcription Factors - metabolism | Deoxyribonuclease I - metabolism | DNA Methylation | Transcription Initiation Site | Transcription, Genetic | Chromatin - genetics | Evolution, Molecular | Physiological aspects | Genetic research | Chromatin | Research | Human genome | DNA | Proteins | DNA methylation | Mutation | Cells
Journal Article
Nature, ISSN 0028-0836, 09/2012, Volume 489, Issue 7414, pp. 83 - 90
Regulatory factor binding to genomic DNA protects the underlying sequence from cleavage by DNase I, leaving nucleotide-resolution 'footprints'. Using genomic...
RNA-POLYMERASE-II | COMPLEX | HUMAN GENOME | PROTEIN-DNA INTERACTIONS | CHROMATIN | MULTIDISCIPLINARY SCIENCES | IN-VIVO | GENE-EXPRESSION | MICE | DIFFERENTIATION | BINDING | Genomic Imprinting | Genomics | Humans | Molecular Sequence Annotation | Genome, Human - genetics | Regulatory Sequences, Nucleic Acid - genetics | Encyclopedias as Topic | DNA - genetics | DNA Footprinting | DNA-Binding Proteins - metabolism | Transcription Factors - metabolism | Deoxyribonuclease I - metabolism | DNA Methylation | Transcription Initiation Site | Polymorphism, Single Nucleotide - genetics | Physiological aspects | Genetic research | Transcription factors | Research | Genetic regulation | Proteins | Genes | Phylogenetics | Footprints | Genomes | Deoxyribonucleic acid--DNA | Methods | protein occupancy | regulation | chromatin | DNaseI footprinting | ENCODE
RNA-POLYMERASE-II | COMPLEX | HUMAN GENOME | PROTEIN-DNA INTERACTIONS | CHROMATIN | MULTIDISCIPLINARY SCIENCES | IN-VIVO | GENE-EXPRESSION | MICE | DIFFERENTIATION | BINDING | Genomic Imprinting | Genomics | Humans | Molecular Sequence Annotation | Genome, Human - genetics | Regulatory Sequences, Nucleic Acid - genetics | Encyclopedias as Topic | DNA - genetics | DNA Footprinting | DNA-Binding Proteins - metabolism | Transcription Factors - metabolism | Deoxyribonuclease I - metabolism | DNA Methylation | Transcription Initiation Site | Polymorphism, Single Nucleotide - genetics | Physiological aspects | Genetic research | Transcription factors | Research | Genetic regulation | Proteins | Genes | Phylogenetics | Footprints | Genomes | Deoxyribonucleic acid--DNA | Methods | protein occupancy | regulation | chromatin | DNaseI footprinting | ENCODE
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International Journal of Radiation Oncology, Biology, Physics, ISSN 0360-3016, 2013, Volume 86, Issue 5, pp. 822 - 828
Purpose The purpose of this guideline was to provide a clinical framework for the use of radiation therapy after radical prostatectomy as adjuvant or salvage...
Radiology | Hematology, Oncology and Palliative Medicine | CONSENSUS GUIDELINES | ONCOLOGY | BIOCHEMICAL RECURRENCE | RADICAL RETROPUBIC PROSTATECTOMY | RANDOMIZED CLINICAL-TRIAL | POSTOPERATIVE RADIOTHERAPY | POSITIVE SURGICAL MARGINS | TARGET VOLUME | PROGNOSTIC-SIGNIFICANCE | CANCER | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | PROGRESSION | Salvage Therapy - adverse effects | Prostatic Neoplasms - radiotherapy | United States | Humans | Male | Prostate-Specific Antigen - blood | Urology - standards | Salvage Therapy - standards | Societies, Medical | Radiotherapy, Adjuvant - adverse effects | Patient Education as Topic - standards | Prostatectomy | Radiotherapy, Adjuvant - standards | Radiation Oncology - standards | Sects | Medical colleges | Radiotherapy | Nuclear radiation | Surgery | PROSTATE | REVIEWS | SURGERY | PATIENTS | RECOMMENDATIONS | METASTASES | RADIOLOGY AND NUCLEAR MEDICINE | ANTIGENS | RADIOTHERAPY | SIDE EFFECTS
Radiology | Hematology, Oncology and Palliative Medicine | CONSENSUS GUIDELINES | ONCOLOGY | BIOCHEMICAL RECURRENCE | RADICAL RETROPUBIC PROSTATECTOMY | RANDOMIZED CLINICAL-TRIAL | POSTOPERATIVE RADIOTHERAPY | POSITIVE SURGICAL MARGINS | TARGET VOLUME | PROGNOSTIC-SIGNIFICANCE | CANCER | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | PROGRESSION | Salvage Therapy - adverse effects | Prostatic Neoplasms - radiotherapy | United States | Humans | Male | Prostate-Specific Antigen - blood | Urology - standards | Salvage Therapy - standards | Societies, Medical | Radiotherapy, Adjuvant - adverse effects | Patient Education as Topic - standards | Prostatectomy | Radiotherapy, Adjuvant - standards | Radiation Oncology - standards | Sects | Medical colleges | Radiotherapy | Nuclear radiation | Surgery | PROSTATE | REVIEWS | SURGERY | PATIENTS | RECOMMENDATIONS | METASTASES | RADIOLOGY AND NUCLEAR MEDICINE | ANTIGENS | RADIOTHERAPY | SIDE EFFECTS
Journal Article
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Full Text
Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)
Autophagy, ISSN 1554-8627, 01/2016, Volume 12, Issue 1, pp. 1 - 222
stress | chaperone-mediated autophagy | vacuole | autolysosome | macroautophagy | flux | autophagosome | LC3 | lysosome | phagophore | Phagophore | Lysosome | Autolysosome | Flux | Autophagosome | Vacuole | Chaperonemediated autophagy | Macroautophagy | Stress | ACTIVATED PROTEIN-KINASE | ENDOPLASMIC-RETICULUM STRESS | STARVATION-INDUCED AUTOPHAGY | GLUCAGON-INDUCED AUTOPHAGY | CELL BIOLOGY | PROGRAMMED CELL-DEATH | LIFE-SPAN EXTENSION | BETAINE HOMOCYSTEINE METHYLTRANSFERASE | VACUOLAR MEMBRANE DYNAMICS | NF-KAPPA-B | Autophagy - physiology | Biological Assay - methods | Animals | Biological Assay - standards | Computer Simulation | Humans | Life Sciences | Medical and Health Sciences | Medicin och hälsovetenskap
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