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Journal Article
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 05/2016, Volume 113, Issue 21, p. 6023
  Neuropeptide B (NPB) and neuropeptide W (NPW) are endogenous neuropeptide ligands for the G protein-coupled receptors NPBWR1 and NPBWR2. Here we report that... 
Proteins | Immunology | Rodents | Neuropeptides | Ligands | Neuropsychology | Stress response
Journal Article
Science, ISSN 0036-8075, 10/2007, Volume 318, Issue 5847, pp. 71 - 76
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 10/2012, Volume 109, Issue 40, pp. 16184 - 16189
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 4/2005, Volume 102, Issue 15, pp. 5374 - 5379
PCSK9 encodes proprotein convertase subtilisin/kexin type 9a (PCSK9), a member of the proteinase K subfamily of subtilases. Missense mutations in PCSK9 cause... 
Biological Sciences | Lipoproteins | Messenger RNA | Hepatocytes | Secretion | Liver | HDL lipoproteins | Mice | Triglycerides | Cholesterols | Blood plasma | Low-density lipoprotein receptor | Proteinase | Sterol regulatory element-binding protein | SREBP | low-density lipoprotein receptor | LDL RECEPTOR | AUTOSOMAL-DOMINANT HYPERCHOLESTEROLEMIA | MULTIDISCIPLINARY SCIENCES | KNOCKOUT MICE | OVEREXPRESSION | TARGET GENES | proteinase | LIVER | DEGRADATION | MUTATIONS | sterol regulatory element-binding protein | lipoproteins | DENSITY-LIPOPROTEIN RECEPTOR | Apolipoproteins B - metabolism | Lovastatin - pharmacology | Cholesterol - blood | Male | Apolipoproteins B - blood | Hepatocytes - metabolism | RNA, Messenger - metabolism | Liver - drug effects | Gene Deletion | Receptors, LDL - deficiency | Serine Endopeptidases - genetics | Female | Proprotein Convertases | Hepatocytes - secretion | Hepatocytes - drug effects | Receptors, LDL - genetics | Serine Endopeptidases - deficiency | Cholesterol - secretion | Electrophoresis, Polyacrylamide Gel | Liver - metabolism | RNA, Messenger - genetics | Cells, Cultured | Receptors, LDL - metabolism | Liver - secretion | Cholesterol - metabolism | Mice, Knockout | Drug Synergism | Phenotype | Animals | Hydroxymethylglutaryl-CoA Reductase Inhibitors - pharmacology | Apolipoproteins B - secretion | Liver - cytology | Serine Endopeptidases - metabolism | Animal Feed | Proprotein Convertase 9 | Proteolipids | Research | Proteases | Cholesterol
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 11/2014, Volume 111, Issue 46, p. 16538
  Why different species are predisposed to different tumor spectra is not well understood. In particular, whether the physical location of tumor suppressor... 
Cysts | Rodents | Genes | Kidney cancer | Mutation | Tumors
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 10/2010, Volume 107, Issue 40, pp. 17362 - 17367
Amyloidogenic processing of the amyloid precursor protein (APP) generates a large secreted ectodomain fragment (APPsβ), β-amyloid (Aβ) peptides, and an APP... 
Proteins | Receptors | Neurons | Liver | Antibodies | Protein precursors | Mice | Gene expression regulation | Amyloids | Synapses | β-secretase | Conditional knockout | Knockin | Alzheimer's disease | Neuromuscular synapse | knockin | neuromuscular synapse | ALZHEIMERS-DISEASE | MULTIDISCIPLINARY SCIENCES | DEFICIENT MICE | CEREBROSPINAL-FLUID | DEPENDENT TRANSCRIPTIONAL CONTROL | MICE LACKING | APOLIPOPROTEIN-E | DEGRADING ENZYME NEPRILYSIN | NEURITE OUTGROWTH | beta-secretase | BETA-PROTEIN | conditional knockout | INTRACELLULAR DOMAINS | Prealbumin - genetics | Humans | Cells, Cultured | Gene Expression Regulation | Glucuronidase - metabolism | Genotype | Neurons - cytology | Gene Expression Profiling | Nerve Tissue Proteins - genetics | Mice, Knockout | Nerve Tissue Proteins - metabolism | Amyloid beta-Protein Precursor - genetics | Animals | Glucuronidase - genetics | Prealbumin - metabolism | Microarray Analysis | Amyloid beta-Protein Precursor - metabolism | Neurons - physiology | Amyloid beta-protein | Physiological aspects | Development and progression | Genetic aspects | Properties | Gene expression | Amyloidogenesis | Neurodegenerative diseases | Transcription | Gene regulation | transthyretin | beta -Amyloid | Lethality | Amyloid precursor protein | Signal transduction | Cell death | Klotho protein | Aging | Pruning | Neuromuscular junctions | Biological Sciences
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 8/2013, Volume 110, Issue 32, pp. 13228 - 13228
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 12/2002, Volume 99, Issue 25, pp. 16237 - 16242
Journal Article