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JOURNAL OF CLINICAL INVESTIGATION, ISSN 0021-9738, 07/2001, Volume 108, Issue 1, pp. 51 - 62
Systemic administration of IL-12 and intermittent doses of IL-2 induce complete regression of metastatic murine renal carcinoma. Here, we show that overt tumor... 
MEDICINE, RESEARCH & EXPERIMENTAL | FAS LIGAND | NATURAL-KILLER-CELLS | STIMULATORY FACTOR | INTERFERON-GAMMA | IN-VIVO | INTERLEUKIN-12 | TUMOR-CELLS | CELL-MEDIATED CYTOTOXICITY | PHASE-I | MURINE RENAL-CANCER | Recombinant Proteins - therapeutic use | Apoptosis - drug effects | Endothelium, Vascular - drug effects | Antineoplastic Agents - therapeutic use | Antineoplastic Agents - administration & dosage | Kidney Neoplasms - surgery | Membrane Glycoproteins - physiology | Neoplasm Metastasis | Nephrectomy | fas Receptor - physiology | Interleukin-12 - pharmacology | Specific Pathogen-Free Organisms | Injections, Intraperitoneal | Angiogenesis Inhibitors - pharmacology | Combined Modality Therapy | Mice, Knockout | Fas Ligand Protein | Interleukin-12 - administration & dosage | Neovascularization, Pathologic - drug therapy | Endothelium, Vascular - pathology | Mice | Mice, Inbred BALB C | CD8-Positive T-Lymphocytes - immunology | Immunologic Factors - pharmacology | Neoplasm Transplantation | Kidney Neoplasms - immunology | Carcinoma, Renal Cell - surgery | Carcinoma, Renal Cell - immunology | Angiogenesis Inhibitors - administration & dosage | Mice, Mutant Strains | Angiogenesis Inhibitors - therapeutic use | Antineoplastic Agents - pharmacology | Interleukin-12 - therapeutic use | Carcinoma, Renal Cell - drug therapy | Carcinoma, Renal Cell - blood supply | Drug Administration Schedule | Immunologic Factors - administration & dosage | Interferon-gamma - physiology | Recombinant Proteins - pharmacology | Mice, Inbred C3H | Recombinant Proteins - administration & dosage | Membrane Glycoproteins - genetics | Animals | Carcinoma, Renal Cell - secondary | Kidney Neoplasms - pathology | Kidney Neoplasms - drug therapy | Kidney Neoplasms - blood supply | Membrane Glycoproteins - deficiency | Immunologic Factors - therapeutic use
Journal Article
Journal of Experimental Medicine, ISSN 0022-1007, 03/2001, Volume 193, Issue 6, pp. 661 - 670
Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is expressed by in vitro activated natural killer (NK) cells, but the relevance of this... 
Inmmunotherapy | Interleukin 12 | Tumor immunity | Rodent | In vivo animal models | interleukin 12 | MEDICINE, RESEARCH & EXPERIMENTAL | NKT CELLS | MEDIATED CYTOTOXICITY | DENDRITIC CELLS | ALPHA-GALACTOSYLCERAMIDE | RECEPTOR EXPRESSION | tumor immunity | IMMUNOLOGY | HUMAN T-CELLS | CUTTING EDGE | IMMUNE-RESPONSES | rodent | in vivo animal models | immunotherapy | IN-VIVO | TUMORICIDAL ACTIVITY | Humans | Membrane Glycoproteins - biosynthesis | Kidney Neoplasms - immunology | Kidney Neoplasms - prevention & control | Galactosylceramides - pharmacology | Carcinoma, Renal Cell - immunology | Tissue Distribution | Neoplasm Metastasis | Interleukin-2 - immunology | TNF-Related Apoptosis-Inducing Ligand | Tumor Necrosis Factor-alpha - immunology | Killer Cells, Natural - immunology | Membrane Glycoproteins - immunology | Tumor Cells, Cultured | Liver Neoplasms - secondary | Cytotoxicity, Immunologic - drug effects | Interleukin-12 - pharmacology | Liver Neoplasms - prevention & control | Liver Neoplasms - immunology | Animals | Apoptosis Regulatory Proteins | Galactosylceramides - immunology | Carcinoma, Renal Cell - secondary | Interferon-gamma - immunology | Interleukin-12 - immunology | Interleukin-2 - pharmacology | Kidney Neoplasms - pathology | Ligands | Mice | Mice, Inbred BALB C | Cytotoxicity, Immunologic - immunology | Tumor Necrosis Factor-alpha - biosynthesis | Original
Journal Article
Journal Article
Journal of Clinical Oncology, ISSN 0732-183X, 06/2009, Volume 27, Issue 16, pp. 2705 - 2711
Journal Article
Immunity, ISSN 1074-7613, 08/2015, Volume 43, Issue 2, pp. 240 - 250
Journal Article
Cancer Cell, ISSN 1535-6108, 04/2013, Volume 23, Issue 4, pp. 527 - 540
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 08/2014, Volume 9, Issue 8, p. e102709
Journal Article
International Journal of Cancer, ISSN 0020-7136, 01/2013, Volume 132, Issue 1, pp. 9 - 18
Mutant KRAS in lung cancers induces molecular pathways that regulate cellular proliferation, survival and inflammation, which enhance tumorigenesis. Inducible... 
lung cancer | KRAS | NOS2 | miR‐21 | inflammation | miR-21 | MAMMALIAN TARGET | NITRIC-OXIDE SYNTHASE | CANCER | MICE LACKING | P53 | ONCOLOGY | UP-REGULATION | TUMOR-GROWTH | T-CELLS | ENDOTHELIAL GROWTH-FACTOR | Inflammation - pathology | T-Lymphocytes, Regulatory - metabolism | Proto-Oncogene Proteins p21(ras) - genetics | Lung Neoplasms - metabolism | Cell Growth Processes - physiology | Lung Neoplasms - pathology | Inflammation - metabolism | Cell Transformation, Neoplastic - genetics | Forkhead Transcription Factors - metabolism | Pulmonary Alveoli - metabolism | Proto-Oncogene Proteins p21(ras) - metabolism | Lung Neoplasms - genetics | Pulmonary Alveoli - pathology | Mice, Inbred C57BL | Nitric Oxide Synthase Type II - deficiency | MicroRNAs - biosynthesis | Forkhead Transcription Factors - genetics | Mutation - genetics | Cell Transformation, Neoplastic - metabolism | Mice, Knockout | Macrophages - metabolism | Animals | Nitric Oxide Synthase Type II - genetics | Inflammation - genetics | Mice | MicroRNAs - genetics | Cell Transformation, Neoplastic - pathology | Nitric Oxide Synthase Type II - metabolism | Lung cancer | Oncology, Experimental | Antisense RNA | Inflammation | Research | T cells | Carcinogenesis | MicroRNA | Nitric oxide | Analysis | Health aspects | Tumors | Cancer | Cell growth | Mutation | MicroRNAs | Index Medicus | Adenoma
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 11/2009, Volume 106, Issue 46, pp. 19455 - 19460
Journal Article
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