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Gene Regulation and Systems Biology, 02/2019, Volume 13
Since the development of high-density microarray technology in the late 1990s, global host gene expression changes in response to various stimuli have been... 
Journal Article
Archives of Biochemistry and Biophysics, ISSN 0003-9861, 07/2013, Volume 535, Issue 2, pp. 163 - 176
Arginase from parasitic protozoa belonging to the genus Leishmania is a potential drug target for the treatment of leishmaniasis because this binuclear... 
Journal Article
Amino acids, ISSN 0939-4451, 04/2019, pp. 1 - 14
Polyamines are metabolites that play important roles in rapidly proliferating cells, and recent studies have highlighted their critical nature in Leishmania... 
Cell proliferation | Phenotypes | Cytology | Ornithine decarboxylase | Parasites | Putrescine | Polyamines | Rounding | Spermidine synthase | Depletion | Metabolites | Morphology | Spermidine | Cell lines | Supplementation | Ornithine | Viability
Journal Article
Experimental Parasitology, ISSN 0014-4894, 06/2011, Volume 128, Issue 2, pp. 166 - 169
► A strategy to re-introduce targeted genes into the original chromosomal locus has been developed. ► A genomic fragment encompassing the ODC gene and lacking... 
Genetic manipulations | Leishmania | Ornithine decarboxylase
Journal Article
Archives of Biochemistry and Biophysics, ISSN 0003-9861, 07/2013, Volume 535, Issue 2, pp. 163 - 176
Journal Article
Journal Article
Infection and Immunity, ISSN 0019-9567, 02/2009, Volume 77, Issue 2, pp. 756 - 763
Mutations within the polyamine biosynthetic pathway of Leishmania donovani, the etiological agent of visceral leishmaniasis, confer polyamine auxotrophy to the... 
Journal Article
Journal Article
Journal of Immunology, ISSN 0022-1767, 12/2007, Volume 179, Issue 12, pp. 8446 - 8453
Classical activation of macrophages infected with Leishmania species results in expression and activation of inducible NO synthase (iNOS) leading to... 
Journal Article
Gene regulation and systems biology, ISSN 1177-6250, 2019, Volume 13, p. 1177625019828350
Since the development of high-density microarray technology in the late 1990s, global host gene expression changes in response to various stimuli have been... 
Journal Article
Journal Article
American Journal of Pharmaceutical Education, ISSN 0002-9459, 03/2010, Volume 74, Issue 3, p. 1
  To assess the impact of a program to integrate introductory pharmacy practice experiences with pharmaceutical science topics by promoting active learning,... 
Design | Core curriculum | Integrated approach | Critical thinking | Independent study | Data collection | Accreditation
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 05/2004, Volume 279, Issue 22, p. 23668
The polyamine pathway of protozoan parasites has been successfully targeted in anti-parasitic therapies and is significantly different from that of the... 
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 07/2009, Volume 284, Issue 30, pp. 19800 - 19807
Journal Article
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