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Nucleic acids research, ISSN 0305-1048, 01/2020, Volume 48, Issue 2, pp. 665 - 681
Sirtuins 1 and 2 (SIRT1/2) are two NAD-dependent deacetylases with major roles in inflammation. In addition to deacetylating histones and other proteins,... 
Journal Article
Journal Article
Journal Article
Methods in molecular biology (Clifton, N.J.), ISSN 1064-3745, 2014, Volume 1094, pp. 309 - 318
Chromatin plays important functions in regulating many biological processes, including DNA transcription, replication, and repair. The use of chromatin... 
Histone modifi cations | Chromatin | ChIP | Transcription factor | DNA binding | Chromatin - metabolism | Sonication | Chromatin Immunoprecipitation - methods | Animals | Cross-Linking Reagents - chemistry | Electrophoresis, Agar Gel
Journal Article
Journal Article
Clinical Immunology, ISSN 1521-6616, 11/2018, Volume 196, pp. 64 - 71
Compelling evidences highlight the critical role of the tumor microenvironment as mediator of tumor progression and immunosuppression in several types of... 
OXIDATIVE STRESS | DENDRITIC CELLS | ABERRANT DNA METHYLATION | GENE-EXPRESSION | SUPPRESSOR-CELLS | DRUG-RESISTANCE | OVARIAN-CANCER | IMMUNOLOGY | MYELOID CELLS | HELICOBACTER-PYLORI | MESENCHYMAL STEM-CELLS | Epigenetic inheritance | Medical research | Immunotherapy | Cancer cells | Medicine, Experimental | Development and progression | Methylation | Gene expression | Cancer
Journal Article
Genome Biology, ISSN 1474-7596, 2016, Volume 17, Issue 1, p. 4
Background: The role of cytokines in establishing specific transcriptional programmes in innate immune cells has long been recognized. However, little is known... 
IL-4 | TET2 | Dendritic cell | DNA demethylation | STAT6 | differentiation | TRANSCRIPTION FACTORS | METHYLATION | INTERLEUKIN-4 | ACTIVATION | SPECIFICITY | NECROSIS-FACTOR-ALPHA | TARGET GENES | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | INFLAMMATION | GENETICS & HEREDITY | 5-HYDROXYMETHYLCYTOSINE | Monocytes - cytology | Humans | Interleukin-4 - metabolism | Gene Expression Regulation | Immunity, Innate - genetics | Monocytes - metabolism | Proto-Oncogene Proteins - genetics | DNA Methylation - genetics | Macrophage Colony-Stimulating Factor - metabolism | STAT6 Transcription Factor - genetics | STAT6 Transcription Factor - metabolism | DNA-Binding Proteins - genetics | Cell Differentiation - genetics | Dendritic Cells - cytology | Interleukin-4 - genetics | Macrophage Colony-Stimulating Factor - genetics | Transcription factors | Dendritic cells | Cytokines | Transcription | Granulocyte-macrophage colony-stimulating factor | Effector cells | Inflammation | Gene expression | Kinases | Signal transduction | Demethylation | Monocytes | Interleukin 4 | Cell activation | Stat6 protein | DNA methylation | Epigenetics | Tumor necrosis factor-TNF | Colony-stimulating factor | Genetic engineering | Bioinformatics | Deoxyribonucleic acid--DNA | Metilació | Cèl·lules dendrítiques | DNA | Diferenciació cel·lular | Transcripció genètica | ADN | Genetic transcription | Methylation | Cell diferentiation | Research
Journal Article
Current Opinion in Pharmacology, ISSN 1471-4892, 2017, Volume 35, pp. 20 - 29
Highlights • Myeloid cell dysregulation is a hallmark of cancer. • Epigenetic enzymes control aberrant activation and suppressive features of myeloid cells. •... 
Internal Medicine | Medical Education | MULTIPLE-MYELOMA | DENDRITIC CELL-DIFFERENTIATION | GM-CSF | HEMATOPOIETIC STEM-CELLS | IN-VIVO | INHIBITS OSTEOCLASTOGENESIS | PHARMACOLOGY & PHARMACY | SUPPRESSOR-CELLS | OSTEOCLAST DIFFERENTIATION | MACROPHAGE DIFFERENTIATION | MHC CLASS-II
Journal Article
Journal Article
Genome Biology, ISSN 1474-7596, 01/2015, Volume 16, Issue 1, pp. 2 - 2
Journal Article
Journal Article
Journal Article