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Annals of Surgical Oncology, ISSN 1068-9265, 2016, Volume 23, Issue 9, pp. 2745 - 2752
Journal Article
Cancer Research, ISSN 0008-5472, 2017, Volume 77, Issue 16, pp. 4279 - 4292
Despite intensive multimodal treatment of sarcomas, a heterogeneous group of malignant tumors arising from connective tissue, survival remains poor.... 
ANAPLASTIC LYMPHOMA KINASE | PROTEIN | ONCOLOGY | PATHWAY | C-MET | INHIBITOR | EXPRESSION | TUMORS | SOFT-TISSUE SARCOMA | RECEPTOR TYROSINE KINASE | HUMAN CANCER | Proto-Oncogene Proteins c-met - metabolism | Sarcoma, Synovial - enzymology | Phosphorylation | Humans | Molecular Targeted Therapy | Sulfones - pharmacology | Receptor Protein-Tyrosine Kinases - antagonists & inhibitors | Female | Pyrazoles - pharmacology | Receptor, Platelet-Derived Growth Factor alpha - biosynthesis | Signal Transduction | Proto-Oncogene Proteins c-met - antagonists & inhibitors | Pyrimidines - pharmacology | Receptor Protein-Tyrosine Kinases - metabolism | Sulfonamides - pharmacology | Proto-Oncogene Proteins c-met - genetics | Xenograft Model Antitumor Assays | Animals | Sarcoma, Synovial - genetics | Receptor Protein-Tyrosine Kinases - genetics | Sarcoma, Synovial - drug therapy | Proteomics | Cell Line, Tumor | Mice | Mice, Inbred BALB C | Protein Kinase Inhibitors - pharmacology | Pyridines - pharmacology | Cohort Studies | Tyrosine | Drugs | Biotechnology | Profiling | Sarcoma | Synovial sarcoma | Mass spectroscopy | Tumor cell lines | Drug development | Kinases | Vascular endothelial growth factor receptors | Connective tissues | Synergistic effects | Angiogenesis | Signaling | Inhibitors | Clonal deletion | Cell lines | Deletion | Mass spectrometry | Tumors | Cancer
Journal Article
Journal Article
International Journal of Cancer, ISSN 0020-7136, 2014, Volume 135, Issue 12, pp. 2770 - 2782
Journal Article
Journal Article
European Journal of Cancer, ISSN 0959-8049, 2013, Volume 49, Issue 16, pp. 3462 - 3470
Abstract Background Rhabdomyosarcoma (RMS) is an aggressive soft tissue tumour mainly affecting children and adolescents. Since survival of high-risk patients... 
Hematology, Oncology and Palliative Medicine | Anaplastic lymphoma kinase receptor | Insulin-like growth factor 1 receptor | Embryonal rhabdomyosarcoma | Targeted treatment | In vitro | Alveolar rhabdomyosarcoma | METASTATIC RHABDOMYOSARCOMA | MONOCLONAL-ANTIBODY | MECHANISMS | COMBINATION | ONCOLOGY | RESISTANCE | INTERGROUP | OUTCOMES | INHIBITOR | IGF-1 RECEPTOR | EXPRESSION | Receptor, IGF Type 1 - metabolism | Receptor, IGF Type 1 - antagonists & inhibitors | Humans | Middle Aged | Child, Preschool | Infant | Molecular Targeted Therapy | Antineoplastic Combined Chemotherapy Protocols - pharmacology | Dose-Response Relationship, Drug | Young Adult | Netherlands | Rhabdomyosarcoma, Alveolar - mortality | Receptor Protein-Tyrosine Kinases - antagonists & inhibitors | Adult | Rhabdomyosarcoma, Alveolar - pathology | Child | Infant, Newborn | Rhabdomyosarcoma, Embryonal - pathology | Rhabdomyosarcoma, Alveolar - drug therapy | Cell Survival - drug effects | Rhabdomyosarcoma, Embryonal - enzymology | Kaplan-Meier Estimate | Rhabdomyosarcoma, Embryonal - mortality | Rhabdomyosarcoma, Embryonal - drug therapy | Chi-Square Distribution | Receptor Protein-Tyrosine Kinases - metabolism | Drug Synergism | Rhabdomyosarcoma, Alveolar - enzymology | Adolescent | Cell Line, Tumor | Aged | Protein Kinase Inhibitors - pharmacology | Lymphomas
Journal Article
Journal Article
European Journal of Cancer, ISSN 0959-8049, 2013, Volume 49, Issue 13, pp. 2851 - 2858
Journal Article
Future Oncology, ISSN 1479-6694, 11/2013, Volume 9, Issue 11, pp. 1733 - 1740
Aim: The aim of this study was to examine the expression of the IGF signaling pathway components in osteosarcoma samples before and after chemotherapy with... 
osteogenic | sarcoma | IGF1 | chemotherapy | PKB | RAPAMYCIN | DISTINCT | ANTITUMOR-ACTIVITY | COMBINATION | CANCER | ANTIBODY IMC-A12 | ONCOLOGY | AKT2 | GROWTH | FACTOR-I RECEPTOR | EXPRESSION
Journal Article
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