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life sciences & biomedicine (23) 23
science & technology (23) 23
humans (18) 18
cell biology (11) 11
male (11) 11
oncology (11) 11
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hematology (10) 10
abridged index medicus (8) 8
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aged (6) 6
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biochemistry (5) 5
hodgkin disease - pathology (5) 5
aged, 80 and over (4) 4
b-cell lymphoma (4) 4
chromosomes, human, pair 9 (4) 4
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immunohistochemistry (4) 4
lymphocytes b (4) 4
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lymphoma, large b-cell, diffuse - pathology (4) 4
programmed cell death 1 ligand 2 protein - genetics (4) 4
treatment outcome (4) 4
39 (3) 3
biochemistry & molecular biology (3) 3
cancer (3) 3
chromosome aberrations (3) 3
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hodgkin disease - therapy (3) 3
immunotherapy (3) 3
medicine, research & experimental (3) 3
mutation (3) 3
neoplasm staging (3) 3
pd-1 (3) 3
pd-l1 (3) 3
programmed cell death 1 receptor - antagonists & inhibitors (3) 3
programmed cell death 1 receptor - immunology (3) 3
research & experimental medicine (3) 3
young adult (3) 3
12 (2) 2
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antibodies, monoclonal - therapeutic use (2) 2
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autoimmunity (2) 2
b7-h1 antigen - analysis (2) 2
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beta 2-microglobulin - genetics (2) 2
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brief report (2) 2
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copy number (2) 2
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genes, neoplasm (2) 2
genetic aspects (2) 2
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hematopoietic stem cell transplantation - adverse effects (2) 2
high grade b cell lymphoma (2) 2
histocompatibility antigens class ii - genetics (2) 2
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hodgkin lymphoma (2) 2
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in situ hybridization, fluorescence (2) 2
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lymphomas (2) 2
marginal zone lymphoma (2) 2
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nivolumab (2) 2
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non-hodgkin's lymphomas (2) 2
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1. Full Text Discovery and Characterization of Super-Enhancer-Associated Dependencies in Diffuse Large B Cell Lymphoma
by Chapuy, Bjoern and McKeown, Michael R and Lin, Charles Y and Monti, Stefano and Roemer, Margaretha G.M and Qi, Jun and Rahl, Peter B and Sun, Heather H and Yeda, Kelly T and Doench, John G and Reichert, Elaine and Kung, Andrew L and Rodig, Scott J and Young, Richard A and Shipp, Margaret A and Bradner, James E
Cancer cell, ISSN 1535-6108, 12/2013, Volume 24, Issue 6, pp. 777 - 790
Oncology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Promoter Regions, Genetic | Humans | Genes, myc | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Trans-Activators - physiology | Azepines - pharmacology | Triazoles - pharmacology | Enhancer Elements, Genetic | Transcription, Genetic | Nuclear Proteins - genetics | Lymphoma, Large B-Cell, Diffuse - genetics | Proto-Oncogene Proteins c-bcl-6 | Proteins | Lymphomas | Biochemical genetics | Genomics | Index Medicus
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2. Full Text Nivolumab for classical Hodgkin's lymphoma after failure of both autologous stem-cell transplantation and brentuximab vedotin: a multicentre, multicohort, single-arm phase 2 trial
by Younes, Anas, Prof and Santoro, Armando, Prof and Shipp, Margaret, Prof and Zinzani, Pier Luigi, Prof and Timmerman, John M, MD and Ansell, Stephen, Prof and Armand, Philippe, MD and Fanale, Michelle, MD and Ratanatharathorn, Voravit, MD and Kuruvilla, John, MD and Cohen, Jonathon B, MD and Collins, Graham, MD and Savage, Kerry J, MD and Trneny, Marek, Prof and Kato, Kazunobu, MD and Farsaci, Benedetto, MD and Parker, Susan M, PhD and Rodig, Scott, MD and Roemer, Margaretha G M, MS and Ligon, Azra H, PhD and Engert, Andreas, Prof
The lancet oncology, ISSN 1470-2045, 2016, Volume 17, Issue 9, pp. 1283 - 1294
Hematology, Oncology and Palliative Medicine | Life Sciences & Biomedicine | Oncology | Science & Technology | Prognosis | Follow-Up Studies | Hodgkin Disease - pathology | Humans | Middle Aged | Neoplasm Recurrence, Local - therapy | Salvage Therapy | Neoplasm Recurrence, Local - drug therapy | Antibodies, Monoclonal - therapeutic use | Male | Survival Rate | Transplantation, Autologous | Antineoplastic Agents - therapeutic use | Combined Modality Therapy - adverse effects | Neoplasm Recurrence, Local - pathology | Hodgkin Disease - therapy | Hematopoietic Stem Cell Transplantation - adverse effects | Hodgkin Disease - drug therapy | Adult | Female | Neoplasm Staging | Cohort Studies | Immunoconjugates - adverse effects | Viral antibodies | Antibodies | Transplantation | Stem cells | Tumors | Index Medicus
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3. Full Text PD-L1 expression is characteristic of a subset of aggressive B-cell lymphomas and virus-associated malignancies
by Chen, Benjamin J and Chapuy, Bjoern and Ouyang, Jing and Sun, Heather H and Roemer, Margaretha G. M and Xu, Mina L and Yu, Hongbo and Fletcher, Christopher D. M and Freeman, Gordon J and Shipp, Margaret A and Rodig, Scott J
Clinical cancer research, ISSN 1078-0432, 07/2013, Volume 19, Issue 13, pp. 3462 - 3473
Life Sciences & Biomedicine | Oncology | Science & Technology | Hematologic and hematopoietic diseases | Pharmacology. Drug treatments | Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis | Biological and medical sciences | Multiple tumors. Solid tumors. Tumors in childhood (general aspects) | Medical sciences | Antineoplastic agents | Tumors | Hodgkin Disease - virology | Immunohistochemistry | Gene Expression | Lymphoma, B-Cell - metabolism | Hodgkin Disease - metabolism | Hodgkin Disease - genetics | Humans | Lymphoma - immunology | Lymphoma - genetics | Lymphoma, B-Cell - genetics | B7-H1 Antigen - genetics | Lymphoma - metabolism | B7-H1 Antigen - metabolism | Herpesvirus 8, Human - pathogenicity | Lymphoma, B-Cell - immunology | Hodgkin Disease - immunology | Lymphoma, B-Cell - virology | Herpesvirus 4, Human - pathogenicity | Lymphoma - virology | Index Medicus
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4. Full Text PD-1 blockade with nivolumab in relapsed/refractory primary central nervous system and testicular lymphoma
by Nayak, Lakshmi and Iwamoto, Fabio M and Lacasce, Ann and Mukundan, Srinivasan and Roemer, Margaretha G.M and Chapuy, Bjoern and Armand, Philippe and Rodig, Scott J and Shipp, Margaret A
Blood, ISSN 0006-4971, 06/2017, Volume 129, Issue 23, pp. 3071 - 3073
Life Sciences & Biomedicine | Hematology | Science & Technology | Testicular Neoplasms - therapy | Humans | Lymphoma, B-Cell - therapy | Middle Aged | Neoplasm Recurrence, Local - therapy | Antibodies, Monoclonal - adverse effects | Antibodies, Monoclonal - therapeutic use | Central Nervous System Neoplasms - therapy | Male | Programmed Cell Death 1 Receptor - antagonists & inhibitors | Tomography, X-Ray Computed | Treatment Outcome | Antineoplastic Agents - therapeutic use | Testicular Neoplasms - diagnostic imaging | Neoplasm Recurrence, Local - diagnostic imaging | Antineoplastic Agents - adverse effects | Central Nervous System Neoplasms - diagnostic imaging | Nivolumab | Aged, 80 and over | Aged | Lymphoma, B-Cell - diagnostic imaging | Programmed Cell Death 1 Receptor - immunology | Index Medicus | Abridged Index Medicus | 33 | 12 | 6 | 39 | 29 | 8 | Clinical Trials and Observations | Brief Report
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5. Full Text Expression of Programmed Cell Death 1 Ligand 2 (PD-L2) Is a Distinguishing Feature of Primary Mediastinal (Thymic) Large B-cell Lymphoma and Associated With PDCD1LG2 Copy Gain
by Shi, Min and Roemer, Margaretha G.M and Chapuy, Bjoern and Liao, Xiaoyun and Sun, Heather and Pinkus, Geraldine S and Shipp, Margaret A and Freeman, Gordon J and Rodig, Scott J
The American journal of surgical pathology, ISSN 0147-5185, 12/2014, Volume 38, Issue 12, pp. 1715 - 1723
PD-L2 | PDCD1LG2 | PD-1 | Primary mediastinal large B-cell lymphoma | Diffuse large B-cell lymphoma | Pathology | Life Sciences & Biomedicine | Surgery | Science & Technology | Immunohistochemistry | Lymphoma, Large B-Cell, Diffuse - diagnosis | Diagnosis, Differential | Gene Amplification | Biomarkers, Tumor - analysis | Programmed Cell Death 1 Ligand 2 Protein - genetics | Humans | Lymphoma, B-Cell - diagnosis | Programmed Cell Death 1 Ligand 2 Protein - biosynthesis | Polymerase Chain Reaction | Gene Dosage | Mediastinal Neoplasms - diagnosis | Index Medicus | Primary Mediastinal Large B-cell Lymphoma | Diffuse Large B-cell Lymphoma
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6. Full Text PD-L1 and PD-L2 Genetic Alterations Define Classical Hodgkin Lymphoma and Predict Outcome
by Roemer, Margaretha G. M and Advani, Ranjana H and Ligon, Azra H and Natkunam, Yasodha and Redd, Robert A and Homer, Heather and Connelly, Courtney F and Sun, Heather H and Daadi, Sarah E and Freeman, Gordon J and Armand, Philippe and Chapuy, Bjoern and de Jong, Daphne and Hoppe, Richard T and Neuberg, Donna S and Rodig, Scott J and Shipp, Margaret A
Journal of clinical oncology, ISSN 0732-183X, 08/2016, Volume 34, Issue 23, pp. 2690 - +
Life Sciences & Biomedicine | Oncology | Science & Technology | Doxorubicin - therapeutic use | Hodgkin Disease - genetics | Hodgkin Disease - pathology | Humans | Middle Aged | Male | Vinblastine - therapeutic use | Chemoradiotherapy | Mechlorethamine - therapeutic use | DNA Copy Number Variations | Young Adult | Bleomycin - therapeutic use | Adult | Female | Programmed Cell Death 1 Ligand 2 Protein - analysis | Programmed Cell Death 1 Ligand 2 Protein - genetics | Risk Factors | Etoposide - therapeutic use | In Situ Hybridization, Fluorescence | Treatment Outcome | Chromosomes, Human, Pair 9 | B7-H1 Antigen - genetics | Disease-Free Survival | Gene Amplification | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Hodgkin Disease - therapy | Adolescent | Chromosome Aberrations | Vincristine - therapeutic use | Aged | B7-H1 Antigen - analysis | Neoplasm Staging | Prednisone - therapeutic use | Index Medicus | Hema16 | Hema27 | ORIGINAL REPORTS
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7. Full Text Molecular subtypes of diffuse large B cell lymphoma are associated with distinct pathogenic mechanisms and outcomes
by Chapuy, Bjoern and Stewart, Chip and Dunford, Andrew J and Kim, Jaegil and Kamburov, Atanas and Redd, Robert A and Lawrence, Mike S and Roemer, Margaretha G. M and Li, Amy J and Ziepert, Marita and Staiger, Annette M and Wala, Jeremiah A and Ducar, Matthew D and Leshchiner, Ignaty and Rheinbay, Ester and Taylor-Weiner, Amaro and Coughlin, Caroline A and Hess, Julian M and Pedamallu, Chandra S and Livitz, Dimitri and Rosebrock, Daniel and Rosenberg, Mara and Tracy, Adam A and Horn, Heike and Van Hummelen, Paul and Feldman, Andrew L and Link, Brian K and Novak, Anne J and Cerhan, James R and Habermann, Thomas M and Siebert, Reiner and Rosenwald, Andreas and Thorner, Aaron R and Meyerson, Matthew L and Golub, Todd R and Beroukhim, Rameen and Wulf, Gerald G and Ott, German and Rodig, Scott J and Monti, Stefano and Neuberg, Donna S and Loeffler, Markus and Pfreundschuh, Michael and Trümper, Lorenz and Getz, Gad and Shipp, Margaret A
Nature medicine, ISSN 1078-8956, 05/2018, Volume 24, Issue 5, pp. 679 - 690
Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Cell Biology | Research & Experimental Medicine | Lymphoma, Large B-Cell, Diffuse - pathology | Genes, Neoplasm | Humans | Mutation Rate | Treatment Outcome | DNA Copy Number Variations - genetics | Gene Rearrangement - genetics | Mutation - genetics | Lymphoma, Large B-Cell, Diffuse - genetics | Genetic Heterogeneity | Oncology, Experimental | Development and progression | Genetic aspects | Non-Hodgkin's lymphomas | B cells | Research | Identification and classification | Health aspects | Cancer | Deactivation | Stability | Transcription | Pathogenesis | Copy number | p53 Protein | Malignancy | Inactivation | Clustering | Lymphoma | Molecular chains | Genomic instability | Alterations | Lymphocytes B | Genetic analysis | New combinations | Adults | Mutation | Signatures | B-cell lymphoma | Index Medicus
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8. Full Text Nivolumab for Relapsed/Refractory Diffuse Large B-Cell Lymphoma in Patients Ineligible for or Having Failed Autologous Transplantation : A Single-Arm, Phase II Study
by Ansell, Stephen M and Minnema, Monique C and Johnson, Peter and Timmerman, John M and Armand, Philippe and Shipp, Margaret A and Rodig, Scott J and Ligon, Azra H and Roemer, Margaretha G M and Reddy, Nishitha and Cohen, Jonathon B and Assouline, Sarit and Poon, Michelle and Sharma, Manish and Kato, Kazunobu and Samakoglu, Selda and Sumbul, Anne and Grigg, Anew
Journal of clinical oncology, ISSN 0732-183X, 02/2019, Volume 37, Issue 6, pp. 481 - 489
Hematopoietic Stem Cell Transplantation/adverse effects | Clinical Trial, Phase II | Humans | Middle Aged | Male | Journal Article | Research Support, N.I.H., Extramural | Young Adult | Time Factors | Treatment Failure | Aged, 80 and over | Adult | Female | Nivolumab/adverse effects | Chromosomes, Human, Pair 9 | Remission Induction | Disease Progression | Transplantation, Autologous/adverse effects | Lymphoma, Large B-Cell, Diffuse/drug therapy | Research Support, Non-U.S. Gov't | Progression-Free Survival | Multicenter Study | Aged | Programmed Cell Death 1 Receptor/antagonists & inhibitors | Antineoplastic Agents, Immunological/adverse effects | Life Sciences & Biomedicine | Oncology | Science & Technology | Programmed Cell Death 1 Receptor - antagonists & inhibitors | Hematopoietic Stem Cell Transplantation - adverse effects | Lymphoma, Large B-Cell, Diffuse - immunology | Lymphoma, Large B-Cell, Diffuse - drug therapy | Lymphoma, Large B-Cell, Diffuse - surgery | Nivolumab - therapeutic use | Nivolumab - adverse effects | Antineoplastic Agents, Immunological - adverse effects | Antineoplastic Agents, Immunological - therapeutic use | Transplantation, Autologous - adverse effects | Programmed Cell Death 1 Receptor - immunology | Lymphoma, Large B-Cell, Diffuse - genetics | Index Medicus | ORIGINAL REPORTS
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9. Full Text Topological analysis reveals a PD-L1-associated microenvironmental niche for Reed-Sternberg cells in Hodgkin lymphoma
by Carey, Christopher D and Gusenleitner, Daniel and Lipschitz, Mikel and Roemer, Margaretha G.M and Stack, Edward C and Gjini, Evisa and Hu, Xihao and Redd, Robert and Freeman, Gordon J and Neuberg, Donna and Hodi, F. Stephen and Liu, Xiaole Shirley and Shipp, Margaret A and Rodig, Scott J
Blood, ISSN 0006-4971, 11/2017, Volume 130, Issue 22, pp. 2420 - 2430
Biochemistry | Immunology | Hematology | Cell Biology | Life Sciences & Biomedicine | Science & Technology | Reed-Sternberg Cells - pathology | Macrophages - pathology | Hodgkin Disease - pathology | Humans | Programmed Cell Death 1 Receptor - analysis | Fluorescent Antibody Technique | Tumor Microenvironment | B7-H1 Antigen - analysis | T-Lymphocytes - pathology | Index Medicus | Abridged Index Medicus | Lymphoid Neoplasia | 12 | 39
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10. Full Text Targetable genetic features of primary testicular and primary central nervous system lymphomas
by Chapuy, Bjoern and Roemer, Margaretha G. M and Stewart, Chip and Tan, Yuxiang and Abo, Ryan P and Zhang, Liye and Dunford, Anew J and Meredith, David M and Thorner, Aaron R and Jordanova, Ekaterina S and Liu, Gang and Feuerhake, Frieich and Ducar, Matthew D and Illerhaus, Gerald and Gusenleitner, Daniel and Linden, Erica A and Sun, Heather H and Homer, Heather and Aono, Miyuki and Pinkus, Geraldine S and Ligon, Azra H and Ligon, Keith L and Ferry, Judith A and Freeman, Gordon J and van Hummelen, Paul and Golub, Todd R and Getz, Gad and Rodig, Scott J and de Jong, Daphne and Monti, Stefano and Shipp, Margaret A
Blood, ISSN 0006-4971, 2016, Volume 127, Issue 7, pp. 869 - 881
Life Sciences & Biomedicine | Hematology | Science & Technology | Central Nervous System Neoplasms - metabolism | Translocation, Genetic | Testicular Neoplasms - genetics | Mediastinal Neoplasms - genetics | Lymphoma, Large B-Cell, Diffuse - pathology | Central Nervous System Neoplasms - genetics | Humans | Testicular Neoplasms - metabolism | Male | Genetic Loci | Lymphoma, Large B-Cell, Diffuse - metabolism | Neoplasm Proteins - metabolism | Testicular Neoplasms - pathology | Central Nervous System Neoplasms - pathology | Mediastinal Neoplasms - pathology | Female | Mediastinal Neoplasms - metabolism | Neoplasm Proteins - genetics | Lymphoma, Large B-Cell, Diffuse - genetics | Index Medicus | Abridged Index Medicus | Lymphoid Neoplasia
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