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1. Full Text The IL-23/IL-17 pathway in human chronic inflammatory diseases-new insight from genetics and targeted therapies
by Bianchi, E and Rogge, L
GENES AND IMMUNITY, ISSN 1466-4879, 05/2019, Volume 20, Issue 5, pp. 415 - 425
Chronic inflammatory diseases such as rheumatoid arthritis, inflammatory bowel disease, spondyloarthritis, and psoriasis cause significant morbidity and are a... 
USTEKINUMAB | GUT INFLAMMATION | GENETICS & HEREDITY | DOUBLE-BLIND | SUSCEPTIBILITY LOCI | RECEPTOR | INNATE LYMPHOID-CELLS | ANKYLOSING-SPONDYLITIS | IMMUNOLOGY | IL-23 | INTERLEUKIN-12/23 MONOCLONAL-ANTIBODY | GENOME-WIDE ASSOCIATION | Genome-wide association studies | Inflammatory bowel diseases | Analysis | Rheumatoid arthritis | Development and progression | Genetic aspects | Diagnosis | Quality of life | Rheumatoid factor | Medical research | Psoriasis | Genomics | Genetic research | Medicine, Experimental | Arthritis | Genetic translation | Pathogenesis | Rheumatic diseases | Interleukin 23 | Genomes | Morbidity | Inflammatory diseases | Interleukin 17 | Genetic variance | Pain | Intestine | Immune system
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2. Full Text Anti-TNF Therapy in Spondyloarthritis and Related Diseases, Impact on the Immune System and Prediction of Treatment Responses
by Menegatti, S and Bianchi, E and Rogge, L
FRONTIERS IN IMMUNOLOGY, ISSN 1664-3224, 03/2019, Volume 10, p. 382
Immune-mediated inflammatory diseases (IMIDs), such as spondyloarthritis (SpA), psoriasis, Crohn's disease (CD), and rheumatoid arthritis (RA) remain... 
C-REACTIVE PROTEIN | WHOLE-BLOOD CULTURES | ALPHA MONOCLONAL-ANTIBODY | COLLAGEN-INDUCED ARTHRITIS | effects of TNF-blockers on the immune system | prediction of responses to anti-TNF therapy | CIRCULATING TH17 CELLS | INNATE LYMPHOID-CELLS | IMMUNOLOGY | anti-TNF therapy | spondyloarthritis | TUMOR-NECROSIS-FACTOR | ERYTHROCYTE SEDIMENTATION-RATE | anti-IL-17A therapy | REGULATORY T-CELLS | ENVIRONMENTAL RISK-FACTORS | anti-IL-23 therapy
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3. Full Text The IL-23/IL-17 pathway in human chronic inflammatory diseases – new insight from genetics and targeted therapies
by Bianchi, Elisabetta and Rogge, Lars
Microbes and Infection, ISSN 1286-4579, 06/2019, Volume 21, Issue 5-6, pp. 246 - 253
Chronic inflammatory diseases such as rheumatoid arthritis, inflammatory bowel disease, spondyloarthritis and psoriasis cause significant morbidity and are a... 
INFECTIOUS DISEASES | GUT INFLAMMATION | SUSCEPTIBILITY LOCI | RECEPTOR | MICROBIOLOGY | INNATE LYMPHOID-CELLS | ANKYLOSING-SPONDYLITIS | IMMUNOLOGY | PSORIATIC-ARTHRITIS | INTERLEUKIN-12/23 MONOCLONAL-ANTIBODY | BOWEL-DISEASE | DOUBLE-BLIND | GENOME-WIDE ASSOCIATION
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4. Full Text Author Correction: NFAT primes the human RORC locus for RORγt expression in CD4+T cells
by Yahia-Cherbal, Hanane and Rybczynska, Magda and Lovecchio, Domenica and Stephen, Tharshana and Lescale, Chloé and Placek, Katarzyna and Larghero, Jérome and Rogge, Lars and Bianchi, Elisabetta
Nature Communications, ISSN 2041-1723, 12/2019, Volume 10, Issue 1, pp. 1 - 1
An amendment to this paper has been published and can be accessed via a link at the top of the paper. 
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5. Full Text NFAT primes the human RORC locus for ROR gamma t expression in CD4(+) T cells
by Yahia-Cherbal, H and Rybczynska, M and Lovecchio, D and Stephen, T and Lescale, C and Placek, K and Larghero, J and Rogge, L and Bianchi, E
NATURE COMMUNICATIONS, ISSN 2041-1723, 10/2019, Volume 10, Issue 1, pp. 1 - 17
T helper 17 (Th17) cells have crucial functions in mucosal immunity and the pathogenesis of several chronic inflammatory diseases. The lineage-specific... 
ACTIVATION | TGF-BETA | MULTIDISCIPLINARY SCIENCES | GENE-EXPRESSION | CYTOKINE | GENERATION | NUCLEAR FACTOR | DIFFERENTIATION | TRANSCRIPTIONAL REGULATION | C-MAF | TH17 CELLS | CRISPR | NF-κB protein | Mucosal immunity | Cyclosporins | Pathogenesis | Mucosa | Helper cells | Event-related potentials | T cell receptors | Lymphocytes T | Regulatory sequences | Gene deletion | Gene expression | NF-AT protein | Loci | Inflammatory diseases | CD4 antigen | T-cell receptor | Thymocytes | Clonal deletion | Lymphocytes | Deletion | Conformation
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6. Full Text A thymic pathway of mouse natural killer cell development characterized by expression of GATA-3 and CD127
by Ezine, Sophie and García-Ojeda, Marcos E and Pasqualetto, Valerie and Guy-Grand, Delphine and Di Santo, James P and Rocha, Benedita and Vosshenrich, Christian A J and Samson-Villéger, Sandrine I and Goff, Odile Richard-Le and Enault, Laurence and Cumano, Ana and Rogge, Lars and Corcuff, Erwan
Nature Immunology, ISSN 1529-2908, 11/2006, Volume 7, Issue 11, pp. 1217 - 1224
Natural killer ( NK) cell development is thought to occur in the bone marrow. Here we identify the transcription factor GATA-3 and CD127 ( IL-7R alpha) as... 
PERIPHERAL NK CELLS | EFFECTOR CELLS | DENDRITIC CELLS | IFN-GAMMA | IN-VIVO | LYMPH-NODES | MICE | T-CELL | IMMUNOLOGY | MATURATION | SUBSET | GATA3 Transcription Factor - genetics | Humans | Interleukin-7 - physiology | GATA3 Transcription Factor - biosynthesis | Interleukin-7 Receptor alpha Subunit - biosynthesis | Lymphocyte Subsets - immunology | Lymphocyte Subsets - metabolism | Signal Transduction - immunology | Lymphocyte Subsets - cytology | Killer Cells, Natural - immunology | Interleukin-7 Receptor alpha Subunit - genetics | Thymus Gland - metabolism | Mice, Inbred C57BL | Thymus Gland - cytology | Immunophenotyping | Mice, Transgenic | Cell Differentiation - immunology | Killer Cells, Natural - cytology | Animals | Mice, Nude | Thymus Gland - immunology | Mice | Killer Cells, Natural - metabolism | Cytokines - biosynthesis | Cytotoxicity, Immunologic | Thymus Gland | Killer Cells, Natural | Signal Transduction | Cytokines | Interleukin-7 | Life Sciences | Immunology | Lymphocyte Subsets | Interleukin-7 Receptor alpha Subunit | Cell Differentiation | GATA3 Transcription Factor
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7. Full Text Functional Analysis via Standardized Whole-Blood Stimulation Systems Defines the Boundaries of a Healthy Immune Response to Complex Stimuli
by Duffy, Darragh and Rouilly, Vincent and Libri, Valentina and Hasan, Milena and Beitz, Benoit and David, Mikael and Urrutia, Alejandra and Bisiaux, Aurélie and LaBrie, Samuel T and Dubois, Annick and Boneca, Ivo G and Delval, Cécile and Thomas, Stéphanie and Rogge, Lars and Schmolz, Manfred and Quintana-Murci, Lluis and Albert, Matthew L and Abel, Laurent and Alcover, Andres and Bousso, Philippe and Cumano, Ana and Daëron, Marc and Demangel, Caroline and Deriano, Ludovic and Di Santo, James and Dromer, Françoise and Eberl, Gérard and Enninga, Jost and Freitas, Antonio and Gomperts-Boneca, Ivo and Hercberg, Serge and Lantz, Olivier and Leclerc, Claude and Mouquet, Hugo and Pellegrini, Sandra and Pol, Stanislas and Sakuntabhai, Anavaj and Schwartz, Olivier and Schwikowski, Benno and Shorte, Spencer and Soumelis, Vassili and Tangy, Frédéric and Tartour, Eric and Toubert, Antoine and Ungeheuer, Marie-Noëlle and Milieu Interieur Consortium and Milieu Intérieur Consortium
Immunity, ISSN 1074-7613, 03/2014, Volume 40, Issue 3, pp. 436 - 450
Standardization of immunophenotyping procedures has become a high priority. We have developed a suite of whole-blood, syringe-based assay systems that can be... 
STAPHYLOCOCCUS-EPIDERMIDIS | RECOGNITION | IFN-GAMMA | GENE-EXPRESSION | RIG-I | BIOLOGICAL-ACTIVITIES | PERIPHERAL-BLOOD | IMMUNOLOGY | TNF-ALPHA PRODUCTION | HELICOBACTER-PYLORI | DIFFERENTIAL ROLES | Reproducibility of Results | Cytokines - metabolism | Humans | Inflammation Mediators - blood | Reference Values | Healthy Volunteers | Monitoring, Immunologic - standards | Monitoring, Immunologic - methods | Immunity, Innate - immunology | Inflammation Mediators - metabolism | Antigens - immunology | Adaptive Immunity - immunology | Cytokines - blood | Medical equipment | T cell receptors | Cytokines | Immune system | Adaptive Immunity | Life Sciences | Antigens | Inflammation Mediators | Immunology | Monitoring, Immunologic | Immunity, Innate
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8. Full Text Sulfurimonas subgroup GD17 cells accumulate polyphosphate under fluctuating redox conditions in the Baltic Sea: possible implications for their ecology
by Möller, Lars and Laas, Peeter and Rogge, Andreas and Goetz, Florian and Bahlo, Rainer and Leipe, Thomas and Labrenz, Matthias
ISME Journal, ISSN 1751-7362, 02/2019, Volume 13, Issue 2, pp. 482 - 493
The central Baltic Sea is characterized by a pelagic redox zone exhibiting high dark CO2 fixation rates below the chemocline. These rates are mainly driven by... 
INORGANIC POLYPHOSPHATE | BACTERIA | CHEMOTACTIC RESPONSE | QUANTIFICATION | ESCHERICHIA-COLI | KINASE | ECOLOGY | MICROBIOLOGY | EPSILONPROTEOBACTERIUM | PELAGIC REDOXCLINES | WATERS | STRESS | Scanning electron microscopy | Cell culture | Starvation | Prokaryotes | Chemocline | Carbon dioxide | Variations | Eutrophic environments | Genomes | X-ray spectroscopy | Substrates | Subgroups | Eutrophication | Energy | Nutrients | Chemosynthesis | Sulfur | Carbon capture and storage | Energy dispersive X ray spectroscopy
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9. Full Text IL-12 drives functional plasticity of human group 2 innate lymphoid cells
by Lim, Ai Ing and Lim, Ai Ing and Menegatti, Silvia and Menegatti, Silvia and Bustamante, Jacinta and Bustamante, Jacinta and Le Bourhis, Lionel and Le Bourhis, Lionel and Allez, Matthieu and Allez, Matthieu and Rogge, Lars and Rogge, Lars and Casanova, Jean-Laurent and Casanova, Jean-Laurent and Yssel, Hans and Yssel, Hans and Di Santo, James P and Di Santo, James P
The Journal of experimental medicine, ISSN 0022-1007, 2016, Volume 213, Issue 4, pp. 569 - 583
Group 2 innate lymphoid cells (ILC2) include IL-5- and IL-13-producing CRTh2(+)CD127(+) cells that are implicated in early protective immunity at mucosal... 
MEDICINE, RESEARCH & EXPERIMENTAL | IMMUNITY | NATURAL-KILLER | CYTOKINES | INTERFERON-GAMMA | SUSCEPTIBILITY | CLINICAL-FEATURES | IMMUNOLOGY | MATURATION | EXPRESSION | IMPAIRMENT | Intestines - pathology | Humans | Cells, Cultured | Interleukin-13 - immunology | Male | Immunity, Innate | Crohn Disease - immunology | Intestines - immunology | Interleukin-5 - immunology | Lymphocytes - pathology | Animals | Lymphocytes - immunology | Crohn Disease - pathology | Interferon-gamma - immunology | Interleukin-12 - immunology | Female | Mice
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10. Full Text Natural variation in the parameters of innate immune cells is preferentially driven by genetic factors
by Patin, E and Hasan, M and Bergstedt, J and Rouilly, V and Libri, V and Urrutia, A and Alanio, C and Scepanovic, P and Hammer, C and Jonsson, F and Beitz, B and Quach, H and Lim, YW and Hunkapiller, J and Zepeda, M and Green, C and Piasecka, B and Leloup, C and Rogge, L and Huetz, F and Peguillet, I and Lantz, O and Fontes, M and Santo, JP and Thomas, S and Fellay, J and Duffy, D and Quintana-Murci, L and Albert, ML and Milieu Interieur Consortium and Milieu Intérieur Consortium and The Milieu Intérieur Consortium and ELLIIT: the Linköping-Lund initiative on IT and mobile communication and Mathematics (Faculty of Engineering) and Lund University and Matematik LTH and Institutionen för reglerteknik and Department of Automatic Control and Lunds universitet
NATURE IMMUNOLOGY, ISSN 1529-2908, 03/2018, Volume 19, Issue 3, pp. 302 - 302
The quantification and characterization of circulating immune cells provide key indicators of human health and disease. To identify the relative effects of... 
SYSTEM | PLINK | DISEASE | BLOOD-CELL | INFECTION | IMMUNOLOGY | STABILITY SELECTION | INFERENCE | TRAITS | T-CELLS | GENOME-WIDE ASSOCIATION | Phenotype | Research | Autoimmune diseases | DNA | Flow cytometry | Parameters | Latent infection | Innate immunity | Genomes | Genetic diversity | Leukocytes | Parameter identification | Immunity | Environmental effects | White blood cells | Cytometry | Immunology | Genotyping | Genetic factors | Variation | Deoxyribonucleic acid--DNA | Smoking | Immune system | Life Sciences | Basic Medicine | Immunologi inom det medicinska området | Medical and Health Sciences | Medicin och hälsovetenskap | Immunology in the medical area | Medicinska och farmaceutiska grundvetenskaper
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