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1. Full Text The cells are ambiguous, not the message
by Rohrlich, Pierre S
Blood, ISSN 0006-4971, 07/2018, Volume 132, Issue 3, pp. 239 - 240
In this issue of Blood, Hrusak et al show the superiority of acute lymphoblastic leukemia (ALL) type therapy in most cases of ambiguous lineage acute... 
PHENOTYPE | ACUTE-LEUKEMIA | CLASSIFICATION | HEMATOLOGY
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2. Full Text Live birth after ovarian tissue autograft in a patient with sickle cell disease treated by allogeneic bone marrow transplantation
by Roux, Christophe, M.D., Ph.D and Amiot, Clotilde, M.D., Ph.D and Agnani, Germain, M.D and Aubard, Yves, M.D., Ph.D and Rohrlich, Pierre-Simon, M.D., Ph.D and Piver, Pascal, M.D
Fertility and Sterility, ISSN 0015-0282, 2010, Volume 93, Issue 7, pp. 2413.e15 - 2413.e19
Objective To report the first case of restoration of ovarian activity and live birth after cryopreserved ovarian tissue autograft in a patient without cancer... 
Internal Medicine | Obstetrics and Gynecology | autotransplantation | Ovarian tissue | live birth | cryopreservation | sickle cell disease | Live birth | Sickle cell disease | Cryopreservation | Autotransplantation | CYCLOPHOSPHAMIDE | RESTORATION | FAILURE | CHEMOTHERAPY | PREGNANCY | FERTILITY | OBSTETRICS & GYNECOLOGY | REPRODUCTIVE BIOLOGY | OUTCOMES | XENOGRAFTS | Humans | Live Birth | Transplantation, Autologous | Primary Ovarian Insufficiency - rehabilitation | Bone Marrow Transplantation - methods | Primary Ovarian Insufficiency - therapy | Bone Marrow Transplantation - rehabilitation | Pregnancy | Anemia, Sickle Cell - therapy | Ovary - surgery | Anemia, Sickle Cell - rehabilitation | Pregnancy Complications, Hematologic - therapy | Bone Marrow Transplantation - adverse effects | Adult | Female | Transplantation Conditioning - adverse effects | Ovary - transplantation | Primary Ovarian Insufficiency - etiology | Infant, Newborn | Pregnancy Complications, Hematologic - rehabilitation | Transplantation, Homologous - adverse effects | Life Sciences | Immunology
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3. Full Text Dehydrated hereditary stomatocytosis linked to gain-of-function mutations in mechanically activated PIEZO1 ion channels
by Albuisson, Juliette and Murthy, Swetha E and Bandell, Michael and Coste, Bertrand and Louis-Dit-Picard, Hélène and Mathur, Jayanti and Fénéant-Thibault, Madeleine and Tertian, Gérard and De Jaureguiberry, Jean-Pierre and Syfuss, Pierre-Yves and Cahalan, Stuart and Garçon, Loic and Toutain, Fabienne and Simon Rohrlich, Pierre and Delaunay, Jean and Picard, Véronique and Jeunemaitre, Xavier and Patapoutian, Ardem
Nature Communications, ISSN 2041-1723, 2013, Volume 4, Issue 1, p. 1884
Dehydrated hereditary stomatocytosis is a genetic condition with defective red blood cell membrane properties that causes an imbalance in intracellular cation... 
STOMATIN | PSEUDOHYPERKALEMIA | PROTEIN | ERYTHROCYTES | XEROCYTOSIS | MULTIDISCIPLINARY SCIENCES | DISEASE | MOUSE | DISORDERS | CELL | LOCUS | Recombinant Proteins - metabolism | Amino Acid Sequence | Humans | Middle Aged | Ion Channels - genetics | Molecular Sequence Data | Male | Mutation - genetics | Anemia, Hemolytic, Congenital - genetics | Young Adult | Biomechanical Phenomena | Hydrops Fetalis - genetics | Ion Channel Gating - genetics | Ion Channels - metabolism | DNA Mutational Analysis | Pedigree | Adolescent | Hydrophobic and Hydrophilic Interactions | Adult | Female | Aged | Kinetics | Child | Ion Channels - chemistry | Life Sciences | Human health and pathology | Genetics | Hematology | Human genetics
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4. Full Text Safety and efficacy of allogeneic hematopoietic stem cell transplant after PD-1 blockade in relapsed/refractory lymphoma
by Merryman, Reid W and Kim, Haesook T and Zinzani, Pier Luigi and Carlo-Stella, Carmelo and Ansell, Stephen M and Perales, Miguel-Angel and Avigdor, Abraham and Halwani, Ahmad S and Houot, Roch and Marchand, Tony and Dhedin, Nathalie and Lescaut, Willy and Thiebaut-Bertrand, Anne and François, Sylvie and Stamatoullas-Bastard, Aspasia and Rohrlich, Pierre-Simon and Wallet, Hélène Labussière and Castagna, Luca and Santoro, Armando and Bachanova, Veronika and Bresler, Scott C and Srivastava, Amitabh and Kim, Harim and Pesek, Emily and Chammas, Marie and Reynolds, Carol and Ho, Vincent T and Antin, Joseph H and Ritz, Jerome and Soiffer, Robert J and Armand, Philippe
Blood, ISSN 0006-4971, 03/2017, Volume 129, Issue 10, pp. 1380 - 1388
Anti-programmed cell death protein 1 (PD-1) monoclonal antibodies are being increasingly tested in patients with advanced lymphoma. Following treatment, many... 
LETHALITY | PROGRAMMED DEATH-1 | REFRACTORY HODGKINS LYMPHOMA | UNRELATED DONORS | EUROPEAN GROUP | HEMATOLOGY | VERSUS-HOST-DISEASE | T-CELLS | WORKING PARTY | MARROW TRANSPLANTATION | BLOOD | Antibodies, Monoclonal, Humanized - therapeutic use | Humans | Middle Aged | Neoplasm Recurrence, Local - therapy | Kaplan-Meier Estimate | Antibodies, Monoclonal - therapeutic use | Male | Programmed Cell Death 1 Receptor - antagonists & inhibitors | Antineoplastic Agents - therapeutic use | Combined Modality Therapy | Neoplasm Recurrence, Local - mortality | Lymphoma - mortality | Young Adult | Disease-Free Survival | Allografts | Lymphoma - therapy | Statistics, Nonparametric | Adult | Female | Aged | Retrospective Studies | Hematopoietic Stem Cell Transplantation - methods | Index Medicus | Abridged Index Medicus | Life Sciences | Cancer | Transplantation
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5. Full Text Heterozygous STAT1 gain-of-function mutations underlie an unexpectedly broad clinical phenotype
by Toubiana, J and Okada, S and Hiller, J and Oleastro, M and Lagos Gomez, M and Aldave Becerra, J.C and Ouachee-Chardin, M and Fouyssac, F and Girisha, K.M and Etzioni, A and Montfrans, J. van and Camcioglu, Y and Kerns, L.A and Belohradsky, B and Blanche, S and Bousfiha, A and Roiguez-Gallego, C and Meyts, I and Kisand, K and Reichenbach, J and Renner, E.D and Rosenzweig, S and Grimbacher, B and Veerdonk, F.L. van de and Traidl-Hoffmann, C and Picard, C and Marodi, L and Morio, T and Kobayashi, M and Lilic, D and Milner, J.D and Holland, S and Casanova, J.L and Puel, A and STAT1 Gain Function Study Grp and International STAT1 Gain-of-Function Study Group
Blood, ISSN 0006-4971, 2016, Volume 127, Issue 25, pp. 3154 - 3164
Since their discovery in patients with autosomal dominant (AD) chronic mucocutaneous candidiasis (CMC) in 2011, heterozygous STAT1 gain-of-function (GOF)... 
HYPER-IGE SYNDROME | PROGRESSIVE MULTIFOCAL LEUKOENCEPHALOPATHY | FUNCTION SIGNAL TRANSDUCER | AUTOSOMAL-DOMINANT GAIN | IL-17 IMMUNITY | EX-VIVO | HEMATOLOGY | CHRONIC MUCOCUTANEOUS CANDIDIASIS | HOMOZYGOUS CARD9 MUTATION | T-CELLS | INBORN-ERRORS | Genetic Predisposition to Disease | Genetic Association Studies | Candidiasis, Chronic Mucocutaneous - genetics | Humans | Middle Aged | Child, Preschool | Infant | Male | STAT1 Transcription Factor - genetics | Young Adult | Phenotype | Adolescent | Adult | Female | Heterozygote | Aged | Mutation | Child | Cohort Studies | 100 | Clinical Trials and Observations
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6. DNA damage response defect in Williams-Beuren syndrome
by Guenat, David and Merla, Giuseppe and Deconinck, Eric and Borg, Christophe and Rohrlich, Pierre-Simon
International Journal of Molecular Medicine, ISSN 1107-3756, 03/2017, Volume 39, Issue 3, pp. 622 - 628
Williams-Beuren syndrome (WBS, no. OMIM 194050) is a rare multisystem genetic disorder caused by a microdeletion on chromosome 7q11.23 and characterized by... 
RFC2 | 7q11.23 | DNA damage | Williams-Beuren syndrome | Predisposition | BAZ1B | Non-Hodgkin's lymphoma | Cancer | GTF2I | Williams syndrome | MEDICINE, RESEARCH & EXPERIMENTAL | predisposition | REGION | non-Hodgkin's lymphoma | NON-HODGKIN-LYMPHOMA | cancer | TFII-I | Cell Cycle - genetics | Cell Line | Hydroxyurea - pharmacology | RNA, Small Interfering - genetics | DNA Repair - drug effects | Genetic Predisposition to Disease | Williams Syndrome - genetics | Humans | Gene Silencing | Etoposide - pharmacology | Case-Control Studies | Gene Knockdown Techniques | Dose-Response Relationship, Drug | Williams Syndrome - metabolism | Fibroblasts | Cell Proliferation - drug effects | DNA Damage | Histones - metabolism | Cell Cycle - drug effects
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7. Full Text Adjuvant Corticosteroid Therapy for Chronic Disseminated Candidiasis
by Faézeh Legrand and Marc Lecuit and Bertrand Dupont and Erianna Bellaton and Michel Huerre and Pierre-Simon Rohrlich and Olivier Lortholary
Clinical Infectious Diseases, ISSN 1058-4838, 3/2008, Volume 46, Issue 5, pp. 696 - 702
Background. Chronic disseminated candidiasis (CDC) is typically observed during neutrophil recovery in patients with acute leukemia and requires protracted... 
Antifungals | Candidiasis | Corticosteroids | Liver | Leukemia | Articles and Commentaries | Neutrophils | Biopsies | Fungal infections | Symptoms | Fever | HEPATIC CANDIDIASIS | INFECTIOUS DISEASES | MICROBIOLOGY | ANTIRETROVIRAL THERAPY | AMPHOTERICIN-B | TRANSPLANT RECIPIENTS | IMMUNOLOGY | ACUTE-LEUKEMIA | CANCER-PATIENTS | IMMUNOCOMPROMISED PATIENTS | RECONSTITUTION INFLAMMATORY SYNDROME | SYSTEMIC CANDIDIASIS | HEPATOSPLENIC CANDIDIASIS | Fever - microbiology | Humans | Middle Aged | Child, Preschool | Male | Adrenal Cortex Hormones - therapeutic use | Antifungal Agents - therapeutic use | Immune Reconstitution Inflammatory Syndrome - physiopathology | Time Factors | Candidiasis - drug therapy | Leukemia - complications | Adult | Female | Retrospective Studies | C-Reactive Protein - analysis | Spleen - pathology | Child | Length of Stay | Immune Reconstitution Inflammatory Syndrome - microbiology | Liver Abscess - pathology | Candidiasis - physiopathology | Abdominal Pain - microbiology | Immune Reconstitution Inflammatory Syndrome - pathology | Adrenal Cortex Hormones - adverse effects | Chemotherapy, Adjuvant - methods | Fibrinogen - analysis | Adolescent | Immune Reconstitution Inflammatory Syndrome - drug therapy | Aged | Adrenal Cortex Hormones - administration & dosage | Dosage and administration | Drug therapy | Immune Reconstitution Inflammatory Syndrome | C-Reactive Protein | Adrenal Cortex Hormones | Abdominal Pain | Life Sciences | Immunology | Fibrinogen | Antifungal Agents | Chemotherapy, Adjuvant | Spleen | Liver Abscess
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8. Full Text Impaired Epstein-Barr virus-specific CD8 + T-cell function in X-linked lymphoproliferative disease is restricted to SLAM family-positive B-cell targets
by Hislop, Andrew D and Palendira, Umaimainthan and Leese, Alison M and Arkwright, Peter D and Rohrlich, Pierre S and Tangye, Stuart G and Gaspar, H. Bobby and Lankester, Arjan C and Moretta, Alessandro and Rickinson, Alan B
Blood, ISSN 0006-4971, 10/2010, Volume 116, Issue 17, pp. 3249 - 3257
X-linked lymphoproliferative disease (XLP) is a condition associated with mutations in the signaling lymphocytic activation molecule (SLAM)-associated protein... 
NATURAL-KILLER-CELLS | SAP | DENDRITIC CELLS | FATAL INFECTIOUS-MONONUCLEOSIS | HUMORAL IMMUNITY | RECEPTOR | LYMPHOCYTIC ACTIVATION MOLECULE | HEMATOLOGY | EXPRESSION | GENE-PRODUCT | CUTTING EDGE | Antigens, CD - immunology | Epstein-Barr Virus Infections - immunology | Humans | Cells, Cultured | Herpesvirus 4, Human - immunology | Lymphoproliferative Disorders - complications | Lymphoproliferative Disorders - immunology | Signaling Lymphocytic Activation Molecule Family | Antigen-Presenting Cells - immunology | Receptors, Cell Surface - immunology | B-Lymphocytes - immunology | Signaling Lymphocytic Activation Molecule Family Member 1 | Epstein-Barr Virus Infections - complications | Fibroblasts - immunology | T-Lymphocytes - immunology | CD8-Positive T-Lymphocytes - immunology | Life Sciences | Immunology
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9. Full Text DOCK8 mutation syndrome: A diagnostic challenge for dermatologists
by Moreau, Joséphine and Beaussant-Cohen, Sarah and Aubin, François and Rohrlich, Pierre-Simon and Puzenat, Eve
Acta Dermato-Venereologica, ISSN 0001-5555, 11/2016, Volume 96, Issue 7, pp. 991 - 992
HYPER-IGE SYNDROME | DEDICATOR | DEFICIENCY | CYTOKINESIS 8 DOCK8 | DERMATOLOGY | Diagnosis, Differential | Guanine Nucleotide Exchange Factors - genetics | Job Syndrome - genetics | Job Syndrome - diagnosis | Job Syndrome - therapy | Humans | Hematopoietic Stem Cell Transplantation | Male | Mutation - genetics | Child | Syndrome
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10. Full Text Can a reduced-intensity conditioning regimen cure blastic plasmacytoid dendritic cell neoplasm?
by Leclerc, Mathieu and De Latour, Régis Peffault and Michallet, Mauricette and Blaise, Didier and Chevallier, Patrice and Rohrlich, Pierre-Simon and Turlure, Pascal and Nguyen, Stéphanie and Jardin, Fabrice and Yakoub-Agha, Ibrahim and Maury, Sébastien and French Soc Bone Marrow and French Society of Bone Marrow Transplantation and Cell Therapy
Blood, ISSN 0006-4971, 03/2017, Volume 129, Issue 9, pp. 1227 - 1230
LEUKEMIA | HEMATOLOGY | FOCUS | TRANSPLANTATION | Age Factors | Leukemia, Myeloid, Acute - pathology | Humans | Middle Aged | Dendritic Cells - pathology | Hematopoietic Stem Cell Transplantation | Male | Treatment Outcome | Remission Induction | Cord Blood Stem Cell Transplantation | Young Adult | Disease-Free Survival | Allografts | Adult | Female | Aged | Retrospective Studies | Transplantation Conditioning - methods | France | Leukemia, Myeloid, Acute - therapy
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11. Full Text STAT3 gain of function: A new kid on the block in interstitial lung diseases
by Fabre, Alexandre and Marchal, Sarah and Forbes, Lisa Renee and Vogel, Tiphanie Phillips and Barlogis, Vincent and Triolo, Valérie and Rohrlich, Pierre-Simon and Bérard, Etienne and Frankel, Diane and Ambrosetti, Damien and Soler, Christine and Hoflack, Marie and Baque, Marie and Bosdure, Emmanuelle and Baravalle, Mélisande and Carsin, Ania and Dubus, Jean-Christophe and Giovannini-Chami, Lisa
American Journal of Respiratory and Critical Care Medicine, ISSN 1073-449X, 06/2018, Volume 197, Issue 11, pp. e22 - e23
The patient's medical history included intrauterine growth restriction, severe growth failure (-4 SD), lymphocytic enteropathy with total villous atrophy,... 
RESPIRATORY SYSTEM | CRITICAL CARE MEDICINE | Tomography | Family medical history | Mutation | Autoimmune diseases | Biopsy | Lung diseases | Life Sciences | Human health and pathology | Infectious diseases
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12. Full Text HAEMATOLOGICA
by Vallet, N and de Fontbrune, FS and Loschi, M and Desmier, D and Villate, A and Barraco, F and Chevallier, P and Terriou, L and Yakoub-Agha, I and Ruggeri, A and Mohty, M and Maillard, N and Rohrlich, PS and Ceballos, P and Nguyen, S and Poire, X and Guillerm, G and Tabrizi, R and Farhi, J and Devillier, R and Rubio, MT and Socie, G and de Latour, RP and Soc Francophone Greffe Moelle
HAEMATOLOGICA, ISSN 0390-6078, 02/2018, Volume 103, Issue 3, pp. E103 - E103
COMPLEMENT INHIBITOR ECULIZUMAB | PAROXYSMAL-NOCTURNAL HEMOGLOBINURIA | HEMATOLOGY
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13. Full Text Immunogenicity Evaluation of a Rationally Designed Polytope Construct Encoding HLA-A0201 Restricted Epitopes Derived from Leishmania major Related Proteins in HLA-A2/DR1 Transgenic Mice: Steps toward Polytope Vaccine
by Seyed, N and Taheri, T and Vauchy, C and Dosset, M and Godet, Y and Eslamifar, A and Sharifi, I and Adotevi, O and Borg, C and Rohrlich, PS and Rafati, S
PLOS ONE, ISSN 1932-6203, 10/2014, Volume 9, Issue 10, pp. e108848 - e108848
Background: There are several reports demonstrating the role of CD8 T cells against Leishmania species. Therefore peptide vaccine might represent an effective... 
INTRADERMAL CHALLENGE | IMMUNITY IN-VIVO | PROTECTIVE IMMUNITY | IFN-GAMMA PRODUCTION | BETA-2-MICROGLOBULIN-DEFICIENT MICE | HUMAN CUTANEOUS LEISHMANIASIS | DNA VACCINE | MULTIDISCIPLINARY SCIENCES | MUCOSAL LEISHMANIASIS | TELOMERASE REVERSE-TRANSCRIPTASE | CD8(+) T-CELLS | Leishmaniasis - immunology | HLA-A2 Antigen - genetics | Leishmania major - immunology | Leishmaniasis - prevention & control | Animals | Leishmaniasis Vaccines - immunology | Mice, Transgenic | Mice | Epitopes, T-Lymphocyte - immunology | CD8-Positive T-Lymphocytes - immunology | Infection | Ubiquitin | Histocompatibility antigens | Peptides | HLA histocompatibility antigens | Liquefied petroleum gas | Genetic engineering | Vaccines | T cells | Health aspects | Antigenic determinants | Cytolytic activity | Animal models | Toxicity | CD8 antigen | Vaccination | Cytotoxicity | Lymphocytes T | Histocompatibility antigen H-2 | Infections | Parasites | Proteins | Immunology | Lymphocytes | Parasitic diseases | Coding | Splenocytes | Drb1 protein | Deoxyribonucleic acid--DNA | Enzyme-linked immunosorbent assay | Polytopes | Antigen presentation | Evaluation | Antigens | Transgenic mice | Priming | Epitopes | Chromium radioisotopes | Chemotherapy | Major histocompatibility complex | Immunogenicity | γ-Interferon | Chromium | Histocompatibility antigen HLA | Index Medicus | Deoxyribonucleic acid | DNA
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14. Full Text Outcome after failure of allogeneic hematopoietic stem cell transplantation in children with acute leukemia: A study by the société Francophone de greffe de moelle et de thérapie cellulaire (SFGM-TC)
by Roux, C and Tifratene, K and Socié, G and Galambrun, C and Bertrand, Y and Rialland, F and Jubert, C and Pochon, C and Paillard, C and Sirvent, A and Nelken, B and Vannier, J.P and Freycon, C and Beguin, Y and Raus, N and Yakoub-Agha, I and Mohty, M and Dalle, J.-H and Michel, G and Pradier, C and Peffault De Latour, R and Rohrlich, P.-S
Bone Marrow Transplantation, ISSN 0268-3369, 05/2017, Volume 52, Issue 5, pp. 678 - 682
Allogeneic hematopoietic stem cell transplantation (SCT) contributes to improved outcome in childhood acute leukemia (AL). However, therapeutic options are... 
WORKING-PARTY | EBMT | DONOR LEUKOCYTE INFUSIONS | BONE-MARROW-TRANSPLANTATION | ACUTE MYELOID-LEUKEMIA | IMMUNOLOGY | TRANSPLANTATION | ONCOLOGY | ACUTE LYMPHOBLASTIC-LEUKEMIA | MALIGNANCIES | RELAPSED ACUTE | BLINATUMOMAB | HEMATOLOGY | REMISSION | Acute Disease | Leukemia, Biphenotypic, Acute - therapy | Humans | Leukemia - therapy | Palliative Care | Precursor Cell Lymphoblastic Leukemia-Lymphoma - mortality | Survival Rate | Treatment Outcome | Hematopoietic Stem Cell Transplantation - mortality | Disease Progression | Transplantation, Homologous | Leukemia, Myeloid, Acute - mortality | Precursor Cell Lymphoblastic Leukemia-Lymphoma - therapy | Treatment Failure | Retrospective Studies | Hematopoietic Stem Cell Transplantation - methods | Lymphocyte Transfusion | Child | Leukemia, Biphenotypic, Acute - mortality | Leukemia, Myeloid, Acute - therapy | Leukemia - mortality | Care and treatment | Chemotherapy | Usage | Lymphocytes | Acute leukemia | Transplantation | Research | Hematopoietic stem cells | Cancer
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