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Scientific reports, 11/2016, Volume 6, p. 37986
Melanoma is the most deadly form of skin cancer with a yearly global incidence over 232,000 patients. Individuals with fair skin and red hair exhibit the... 
Journal Article
Cell reports, 06/2017, Volume 19, Issue 11, p. 2177
The presence of dark melanin (eumelanin) within human epidermis represents one of the strongest predictors of low skin cancer risk. Topical rescue of eumelanin... 
Animals | Skin - metabolism | Humans | Mice, Inbred C57BL | Mice, Transgenic | Mice | Administration, Topical | Melanins - metabolism | Ultraviolet Rays - adverse effects | Melanins - biosynthesis
Journal Article
Nature, ISSN 0028-0836, 07/2017, Volume 547, Issue 7664, pp. 453 - 457
Plasticity of the cell state has been proposed to drive resistance to multiple classes of cancer therapies, thereby limiting their effectiveness(1-4). A... 
EPITHELIAL-MESENCHYMAL TRANSITION | METABOLISM | MULTIDISCIPLINARY SCIENCES | PROSTATE-CANCER | HUMAN-MELANOMA CELLS | SENSITIVITY | DEATH | INHIBITOR | EXPRESSION | SIGNATURE | REVEALS | Prostatic Neoplasms - metabolism | Cadherins - metabolism | Humans | Mesoderm - drug effects | Melanoma - enzymology | Male | Lipid Peroxides - metabolism | Zinc Finger E-box-Binding Homeobox 1 - genetics | Neoplasms - genetics | Mesoderm - enzymology | Cell Death | Epithelial-Mesenchymal Transition | Lipid Peroxidation - drug effects | Cell Transdifferentiation | Prostatic Neoplasms - drug therapy | Melanoma - metabolism | Glutathione Peroxidase - metabolism | Prostatic Neoplasms - pathology | Reproducibility of Results | Neoplasms - enzymology | Melanoma - pathology | Iron - metabolism | Neoplasms - drug therapy | Cell Lineage | Drug Resistance, Neoplasm - genetics | Proto-Oncogene Proteins B-raf - genetics | Melanoma - drug therapy | Proteomics | Cell Line, Tumor | Prostatic Neoplasms - enzymology | Mesoderm - metabolism | Neoplasms - pathology | Mesoderm - pathology | Peroxidase | Research | Chemical properties | Chemical synthesis | Analysis | Cancer cells | Therapy | Biotechnology | Carcinoma | Mesenchyme | Genes | Lipid peroxidation | Lipids | Iron | Genomes | Phospholipids | Kinases | Cancer therapies | Proteins | Organoids | Dissipation | Peroxides | Lipid metabolism | Glutathione | Transfer RNA | Peroxidation | Glutathione peroxidase | Enzymes | Mortality | Melanoma | Selenocysteine | Tumor cell lines | Metabolism | Substrates | Cell death | Lipoxygenase | Prostate cancer | Prostate | Tumors | Apoptosis | Cancer | Index Medicus
Journal Article
JAMA Dermatology, ISSN 2168-6068, 07/2016, Volume 152, Issue 7, pp. 751 - 753
Journal Article
Cancer Cell, ISSN 1535-6108, 12/2015, Volume 28, Issue 6, pp. 773 - 784
Journal Article
Journal of Investigative Dermatology, ISSN 0022-202X, 01/2014, Volume 134, Issue 1, pp. 16 - 17
Journal Article
Scientific Reports, ISSN 2045-2322, 11/2016, Volume 6, Issue 1, p. 37986
Melanoma is the most deadly form of skin cancer with a yearly global incidence over 232,000 patients. Individuals with fair skin and red hair exhibit the... 
MULTIDISCIPLINARY SCIENCES | SCATTERING MICROSCOPY | ONE-LASER | Hair | Nests | Ultraviolet radiation | Pheomelanin | U.V. radiation | Melanoma | Melanocytes | Skin cancer
Journal Article
Cell Reports, ISSN 2211-1247, 06/2017, Volume 19, Issue 11, pp. 2177 - 2184
The presence of dark melanin (eumelanin) within human epidermis represents one of the strongest predictors of low skin cancer risk. Topical rescue of eumelanin... 
pigmentation | microphthalmia-associated transcription factor (MITF) | salt-inducible kinase (SIK) | eumelanin | topical drug | UNITED-STATES | ACTIVATION | COLONY-STIMULATING FACTOR | SUN EXPOSURE | GENE | SALT-INDUCIBLE KINASE | RECEPTOR | MITF | CANCER | EXPRESSION | CELL BIOLOGY
Journal Article
by Rodger, Alison J and Cambiano, Valentina and Bruun, Tina and Vernazza, Pietro and Collins, Simon and Degen, Olaf and Corbelli, Giulio Maria and Estrada, Vicente and Estrada, Vicente P and Geretti, Anna Maria and Beloukas, Apostolos and Raben, Dorthe and Coll, Pep and Antinori, Andrea and Nwokolo, Nneka and Rieger, Armin and Prins, Jan M and Prins, Jan and Blaxhult, Anders and Weber, Rainer and Van Eeden, Arne and Brockmeyer, Norbert and Brockmeyer, Norbert H and Clarke, Amanda and del Romero Guerrero, Jorge and Raffi, Francois and Bogner, Johannes R and Bogner, Johannes and Wandeler, Gilles and Gerstoft, Jan and Gutiérrez, Felix and Brinkman, Kees and Kitchen, Maria and Ostergaard, Lars and Leon, Agathe and Ristola, Matti and Jessen, Heiko and Jessen, Arne and Stellbrink, Hans-Jürgen and Phillips, Andrew N and Lundgren, Jens and Cobarsi, Patricia and Nieto, Aroa and Meulbroek, Michael and Carrillo, Antonia and Saz, Jorge and Guerrero, Jorge D.R and García, Mar Vera and Masiá, Mar and Robledano, Catalina and Leal, Lorna and Redondo, Eva G and Marquez, Rocio and Sandoval, Raquel and Viciana, Pompeyo and Espinosa, Nuria and Lopez-Cortes, Luis and Podzamczer, Daniel and Tiraboschi, Juan and Morenilla, Sandra and Antela, Antonio and Losada, Elena and Sewell, Janey and Kirk, Sarah and Knott, Alyson and Fernandez, Thomas and Gompels, Mark and Jennings, Louise and Ward, Lana and Fox, Julie and Lwanga, Julianne and Lee, Ming and Gilson, Richard and Leen, Clifford and Morris, Sheila and Clutterbuck, Dan and Brady, Michael and Asboe, David and Fedele, Serge and Fidler, Sarah and Potthoff, Anja and Skaletz-Rorowski, Adriane and Seybold, Ulrich and Roider, Julia and Ruzicic, Slobodan and Kümmerle, Tim and Lehmann, Clara and Bartel, Sindy and Hüfner, Anja and Rockstroh, Jürgen and Mohrmann, Karina and Boesecke, Christoph and Krznaric, Ivanka and Ingiliz, Patrick and Grube, Christina and Braun, Dominique and Günthard, Huldrych and Furrer, Hansjakob and Rauch, Andri and Schmid, Patrick and ... and PARTNER Study Grp and PARTNER Study Group
The Lancet, ISSN 0140-6736, 06/2019, Volume 393, Issue 10189, pp. 2428 - 2438
Journal Article
Nature Communications, ISSN 2041-1723, 06/2017, Volume 8, Issue 1, p. 15866
Journal Article
PLoS ONE, ISSN 1932-6203, 02/2014, Volume 9, Issue 2, p. e89150
Fucoidan is a polysaccharide isolated from brown algae which is of current interest for anti-tumor therapy. In this study, we investigated the effect of... 
CELLS | ACTIVATION | PHAGOCYTOSIS | HUMAN PERIPHERAL-BLOOD | PATHWAY | BEVACIZUMAB | MULTIDISCIPLINARY SCIENCES | MACULAR DEGENERATION | MECHANISMS | SULFATED POLYSACCHARIDES | BROWN | Immunohistochemistry | Cell Line | Neovascularization, Physiologic - drug effects | Retinal Pigment Epithelium - metabolism | Proteoglycans | Enzyme-Linked Immunosorbent Assay | Humans | Vascular Endothelial Growth Factor A - metabolism | Macular Degeneration - drug therapy | Polysaccharides - pharmacology | Bevacizumab | Gene Expression Regulation - drug effects | Tetrazolium Salts | Antibodies, Monoclonal, Humanized | Microscopy, Confocal | Neovascularization, Physiologic - physiology | Laminin | Collagen | Thiazoles | Trypan Blue | Drug Combinations | Macular degeneration | Care and treatment | Research | Epithelium | Vascular endothelial growth factor | Enzyme-linked immunosorbent assay | Cell proliferation | Therapy | Oxidative stress | Image processing | Toxicity | Immunocytochemistry | Retina | Confocal | Assaying | Retinal pigment epithelium | Angiogenesis | Biomedical materials | Penicillin | Tomography | Calcein | Age | Explants | Wound healing | Secretion | Algae | Cultures | Fucoidan | Gene expression | Endothelial cells | Studies | Image analysis | Perfusion | Photoreceptors | Healing | Exudation | Laboratory animals | Phagocytosis | Cancer | Apoptosis
Journal Article
Marine Drugs, ISSN 1660-3397, 07/2017, Volume 15, Issue 7, p. 193
Background. The polysaccharide fucoidan is widely investigated as an anti-cancer agent. Here, we tested the effect of fucoidan on uveal melanoma cell lines.... 
Uveal melanoma | Angiogenesis | Oxidative stress | Fucoidan | VEGF | APOPTOSIS | ACTIVATION | CHEMISTRY, MEDICINAL | CANCER CELLS | ENDOTHELIAL-GROWTH-FACTOR