Lancet Oncology, The, ISSN 1470-2045, 2013, Volume 14, Issue 11, pp. 1129 - 1140
Summary Background We aimed to assess efficacy and tolerability of vorinostat in combination with bortezomib for treatment of patients with relapsed or...
Hematology, Oncology and Palliative Medicine | TRIAL | HISTONE DEACETYLASE INHIBITOR | CARFILZOMIB | ONCOLOGY | SUBEROYLANILIDE HYDROXAMIC ACID | PROTEASOME | PHASE-I | CANCER | Prognosis | Follow-Up Studies | Multiple Myeloma - mortality | Humans | Middle Aged | Pyrazines - administration & dosage | Salvage Therapy | Neoplasm Recurrence, Local - drug therapy | Male | Neoplasm Recurrence, Local - mortality | Neoplasm Recurrence, Local - pathology | Multiple Myeloma - drug therapy | Aged, 80 and over | Hydroxamic Acids - administration & dosage | Adult | Female | Boronic Acids - administration & dosage | Bortezomib | Double-Blind Method | Survival Rate | Multiple Myeloma - pathology | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Aged | Neoplasm Staging | Drug Resistance, Neoplasm - drug effects | Medicine, Experimental | Medical research | Medical colleges | Care and treatment | Multiple myeloma | Index Medicus
Hematology, Oncology and Palliative Medicine | TRIAL | HISTONE DEACETYLASE INHIBITOR | CARFILZOMIB | ONCOLOGY | SUBEROYLANILIDE HYDROXAMIC ACID | PROTEASOME | PHASE-I | CANCER | Prognosis | Follow-Up Studies | Multiple Myeloma - mortality | Humans | Middle Aged | Pyrazines - administration & dosage | Salvage Therapy | Neoplasm Recurrence, Local - drug therapy | Male | Neoplasm Recurrence, Local - mortality | Neoplasm Recurrence, Local - pathology | Multiple Myeloma - drug therapy | Aged, 80 and over | Hydroxamic Acids - administration & dosage | Adult | Female | Boronic Acids - administration & dosage | Bortezomib | Double-Blind Method | Survival Rate | Multiple Myeloma - pathology | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Aged | Neoplasm Staging | Drug Resistance, Neoplasm - drug effects | Medicine, Experimental | Medical research | Medical colleges | Care and treatment | Multiple myeloma | Index Medicus
Journal Article
Journal of Heart and Lung Transplantation, ISSN 1053-2498, 2016, Volume 35, Issue 3, pp. 261 - 282
Surgery | BRONCHOALVEOLAR LAVAGE GALACTOMANNAN | SURGERY | CARDIAC & CARDIOVASCULAR SYSTEMS | VENTRICULAR-ASSIST DEVICE | B LIPID COMPLEX | ANTIFUNGAL PROPHYLAXIS | CANDIDA-ALBICANS BIOFILMS | LIPOSOMAL AMPHOTERICIN-B | TRANSPLANTATION | CLINICAL-PRACTICE GUIDELINES | INVASIVE PULMONARY ASPERGILLOSIS | RESPIRATORY SYSTEM | SQUAMOUS-CELL CARCINOMA | BLOOD-STREAM INFECTIONS | Mycoses - epidemiology | Prevalence | Heart-Lung Transplantation | Humans | Assisted Circulation | Postoperative Complications - therapy | Postoperative Complications - epidemiology | Postoperative Complications - diagnosis | Incidence | Mycoses - diagnosis | Mycoses - therapy | Adult | Child | Mycoses | Transplantation of organs, tissues, etc | Organ transplant recipients | Medical colleges | Health aspects
Journal Article
American Journal of Cardiology, The, ISSN 0002-9149, 2016, Volume 118, Issue 4, pp. 578 - 584
Abstract Vascular complications in Transfemoral Aortic Valve Implantation (TAVI-TF) are related to higher mortality. Complete percutaneous approach is...
Cardiovascular | REPLACEMENT | TRIAL | VASCULAR COMPLICATIONS | CARDIAC & CARDIOVASCULAR SYSTEMS | PRECLOSE TECHNIQUE | ACCESS SITE CLOSURE | OUTCOMES | PERCUTANEOUS ACCESS | TRANSCATHETER | Length of Stay | Myocardial Infarction - epidemiology | Dissection - methods | Humans | Postoperative Hemorrhage - epidemiology | Kaplan-Meier Estimate | Proportional Hazards Models | Male | Fluoroscopy | Postoperative Complications - epidemiology | Spain | Operative Time | Punctures - methods | Contrast Media | Aged, 80 and over | Female | Femoral Artery | Registries | Aged | Aortic Valve Stenosis - surgery | Transcatheter Aortic Valve Replacement - methods | Heart valve diseases | Valves | Prostheses | Stroke | Heart attacks | Mortality | Cardiovascular disease | Gender | Angina pectoris | Patients | Confidence intervals | Consortia | Body mass index | Survival analysis | Coronary vessels | Cardiology
Cardiovascular | REPLACEMENT | TRIAL | VASCULAR COMPLICATIONS | CARDIAC & CARDIOVASCULAR SYSTEMS | PRECLOSE TECHNIQUE | ACCESS SITE CLOSURE | OUTCOMES | PERCUTANEOUS ACCESS | TRANSCATHETER | Length of Stay | Myocardial Infarction - epidemiology | Dissection - methods | Humans | Postoperative Hemorrhage - epidemiology | Kaplan-Meier Estimate | Proportional Hazards Models | Male | Fluoroscopy | Postoperative Complications - epidemiology | Spain | Operative Time | Punctures - methods | Contrast Media | Aged, 80 and over | Female | Femoral Artery | Registries | Aged | Aortic Valve Stenosis - surgery | Transcatheter Aortic Valve Replacement - methods | Heart valve diseases | Valves | Prostheses | Stroke | Heart attacks | Mortality | Cardiovascular disease | Gender | Angina pectoris | Patients | Confidence intervals | Consortia | Body mass index | Survival analysis | Coronary vessels | Cardiology
Journal Article
Journal of Allergy and Clinical Immunology: In Practice, ISSN 2213-2198, 2017, Volume 5, Issue 4, pp. 1071 - 1081.e9
Background Poor inhaler technique has been linked to poor asthma outcomes. Training can reduce the number of inhaler errors, but it is unknown which errors...
Internal Medicine | Allergy and Immunology | Exacerbation | Asthma control | Inhaler errors | Inhaler technique | LUNG | DRY POWDER INHALERS | KNOWLEDGE | INHALATION TECHNIQUE | OBSTRUCTIVE PULMONARY-DISEASE | PEOPLE | TERBUTALINE SULFATE | CLINICAL-PRACTICE | MEDICATION ADHERENCE | COPD | IMMUNOLOGY | ALLERGY | Humans | Middle Aged | Administration, Inhalation | Male | Treatment Outcome | Asthma - drug therapy | Medication Errors - statistics & numerical data | Young Adult | Metered Dose Inhalers - utilization | Adolescent | Adult | Female | Anti-Asthmatic Agents - administration & dosage | Dry Powder Inhalers - utilization | Respiratory therapy | Corticoids | Data processing | Thorax | Patients | Primary care | Powder | Data bases | Asthma | Inhalation | Studies | Training | Ethics | Aerosols | Chronic obstructive pulmonary disease | Clinical medicine | Respiration | Drug dosages | Basic Medicine | Medical and Health Sciences | Medicin och hälsovetenskap | Immunologi inom det medicinska området | Klinisk medicin | Clinical Medicine | Medicinska och farmaceutiska grundvetenskaper | Lungmedicin och allergi | Respiratory Medicine and Allergy | Immunology in the medical area
Internal Medicine | Allergy and Immunology | Exacerbation | Asthma control | Inhaler errors | Inhaler technique | LUNG | DRY POWDER INHALERS | KNOWLEDGE | INHALATION TECHNIQUE | OBSTRUCTIVE PULMONARY-DISEASE | PEOPLE | TERBUTALINE SULFATE | CLINICAL-PRACTICE | MEDICATION ADHERENCE | COPD | IMMUNOLOGY | ALLERGY | Humans | Middle Aged | Administration, Inhalation | Male | Treatment Outcome | Asthma - drug therapy | Medication Errors - statistics & numerical data | Young Adult | Metered Dose Inhalers - utilization | Adolescent | Adult | Female | Anti-Asthmatic Agents - administration & dosage | Dry Powder Inhalers - utilization | Respiratory therapy | Corticoids | Data processing | Thorax | Patients | Primary care | Powder | Data bases | Asthma | Inhalation | Studies | Training | Ethics | Aerosols | Chronic obstructive pulmonary disease | Clinical medicine | Respiration | Drug dosages | Basic Medicine | Medical and Health Sciences | Medicin och hälsovetenskap | Immunologi inom det medicinska området | Klinisk medicin | Clinical Medicine | Medicinska och farmaceutiska grundvetenskaper | Lungmedicin och allergi | Respiratory Medicine and Allergy | Immunology in the medical area
Journal Article
Seminars in Arthritis and Rheumatism, ISSN 0049-0172, 2012, Volume 41, Issue 6, pp. 789 - 800
Objective To investigate the incidence of clinical and immunological characteristics of a large cohort of Spanish patients with scleroderma (SSc) and...
Rheumatology | systemic sclerosis | SSc sine scleroderma | limited cutaneous SSc | diffuse cutaneous SSc | “prescleroderma” or early scleroderma | anticentromere antibodies | antitopoisomerase I antibodies | Anticentromere antibodies | Antitopoisomerase I antibodies | "prescleroderma" or early scleroderma | Systemic sclerosis | Limited cutaneous SSc | Diffuse cutaneous SSc | ORGAN INVOLVEMENT | SURVIVAL | MORTALITY | POPULATION | PROGNOSTIC-FACTORS | PREVALENCE | RHEUMATOLOGY | SINE SCLERODERMA | SCLERODERMA RENAL CRISIS | CLASSIFICATION CRITERIA | EPIDEMIOLOGY | Pulmonary Fibrosis - diagnosis | Cross-Sectional Studies | Pulmonary Fibrosis - complications | Humans | Middle Aged | Male | Scleroderma, Systemic - immunology | Lung Diseases, Interstitial - complications | Scleroderma, Systemic - epidemiology | Incidence | Scleroderma, Systemic - diagnosis | Lung Diseases, Interstitial - diagnosis | Spain - epidemiology | Scleroderma, Systemic - complications | Adult | Female | Registries | Aged | Viral antibodies | Antibodies | Systemic scleroderma | Scleroderma (Disease)
Rheumatology | systemic sclerosis | SSc sine scleroderma | limited cutaneous SSc | diffuse cutaneous SSc | “prescleroderma” or early scleroderma | anticentromere antibodies | antitopoisomerase I antibodies | Anticentromere antibodies | Antitopoisomerase I antibodies | "prescleroderma" or early scleroderma | Systemic sclerosis | Limited cutaneous SSc | Diffuse cutaneous SSc | ORGAN INVOLVEMENT | SURVIVAL | MORTALITY | POPULATION | PROGNOSTIC-FACTORS | PREVALENCE | RHEUMATOLOGY | SINE SCLERODERMA | SCLERODERMA RENAL CRISIS | CLASSIFICATION CRITERIA | EPIDEMIOLOGY | Pulmonary Fibrosis - diagnosis | Cross-Sectional Studies | Pulmonary Fibrosis - complications | Humans | Middle Aged | Male | Scleroderma, Systemic - immunology | Lung Diseases, Interstitial - complications | Scleroderma, Systemic - epidemiology | Incidence | Scleroderma, Systemic - diagnosis | Lung Diseases, Interstitial - diagnosis | Spain - epidemiology | Scleroderma, Systemic - complications | Adult | Female | Registries | Aged | Viral antibodies | Antibodies | Systemic scleroderma | Scleroderma (Disease)
Journal Article
American Journal of Cardiology, The, ISSN 0002-9149, 2015, Volume 116, Issue 11, pp. 1695 - 1699
Percutaneous intervention of a coronary graft is the treatment of choice when the graft fails. The objective is to report the long-term results of drug-eluting...
Cardiovascular | ANASTOMOSIS | CARDIAC & CARDIOVASCULAR SYSTEMS | ANGIOPLASTY | BYPASS SURGERY | PERCUTANEOUS REVASCULARIZATION | OUTCOMES | PERFORATION | Drug-Eluting Stents | Sirolimus - analogs & derivatives | Humans | Middle Aged | Male | Treatment Outcome | Everolimus - administration & dosage | Internal Mammary-Coronary Artery Anastomosis | Sirolimus - administration & dosage | Female | Aged | Paclitaxel - administration & dosage | Immunosuppressive Agents - administration & dosage | Stent (Surgery) | Heart attacks | Angina pectoris | Stents | Mortality | Veins & arteries
Cardiovascular | ANASTOMOSIS | CARDIAC & CARDIOVASCULAR SYSTEMS | ANGIOPLASTY | BYPASS SURGERY | PERCUTANEOUS REVASCULARIZATION | OUTCOMES | PERFORATION | Drug-Eluting Stents | Sirolimus - analogs & derivatives | Humans | Middle Aged | Male | Treatment Outcome | Everolimus - administration & dosage | Internal Mammary-Coronary Artery Anastomosis | Sirolimus - administration & dosage | Female | Aged | Paclitaxel - administration & dosage | Immunosuppressive Agents - administration & dosage | Stent (Surgery) | Heart attacks | Angina pectoris | Stents | Mortality | Veins & arteries
Journal Article
Chest, ISSN 0012-3692, 2014, Volume 146, Issue 5, pp. 1327 - 1336
BACKGROUND Excessive erythrocytosis (EE) is a prevalent condition in populations living at high altitudes (> 2,500 m above sea level). Few large...
Pulmonary/Respiratory | HEART | HIGH-ALTITUDE | RESPIRATORY SYSTEM | ADAPTATION | HYPOXEMIA | RISK | HIGHLANDERS | SCALE | SELECTION | CHRONIC MOUNTAIN-SICKNESS | AGE | CRITICAL CARE MEDICINE | Polycythemia - ethnology | Prevalence | Humans | Middle Aged | Oximetry | Polycythemia - blood | Male | Reference Values | Ethnic Groups | Adult | Female | Aged | Peru - epidemiology | Altitude | Iron - blood | Usage | Medical examination | Demographic aspects | Polycythemia | Questionnaires | Nutritional aspects | Adults | Iron in the body | Health aspects | Risk factors | Original Research
Pulmonary/Respiratory | HEART | HIGH-ALTITUDE | RESPIRATORY SYSTEM | ADAPTATION | HYPOXEMIA | RISK | HIGHLANDERS | SCALE | SELECTION | CHRONIC MOUNTAIN-SICKNESS | AGE | CRITICAL CARE MEDICINE | Polycythemia - ethnology | Prevalence | Humans | Middle Aged | Oximetry | Polycythemia - blood | Male | Reference Values | Ethnic Groups | Adult | Female | Aged | Peru - epidemiology | Altitude | Iron - blood | Usage | Medical examination | Demographic aspects | Polycythemia | Questionnaires | Nutritional aspects | Adults | Iron in the body | Health aspects | Risk factors | Original Research
Journal Article
The Lancet, ISSN 0140-6736, 01/2015, Volume 385, Issue 9965, pp. 351 - 361
Summary Background Statins increase the risk of new-onset type 2 diabetes mellitus. We aimed to assess whether this increase in risk is a consequence of...
Internal Medicine | LDL CHOLESTEROL | HIGH-DOSE ATORVASTATIN | METAANALYSIS | STATIN THERAPY | ASSOCIATION ANALYSES | DISEASE | PREVENTION | BODY-MASS INDEX | RISK | MENDELIAN RANDOMIZATION | MEDICINE, GENERAL & INTERNAL | Body Mass Index | Genetic Testing | Cholesterol, HDL - metabolism | Diabetes Mellitus, Type 2 - genetics | Humans | Middle Aged | Risk Factors | Male | Body Weight - genetics | Randomized Controlled Trials as Topic | Hydroxymethylglutaryl-CoA Reductase Inhibitors - adverse effects | Cholesterol, LDL - metabolism | Polymorphism, Single Nucleotide - genetics | Female | Aged | Hydroxymethylglutaryl CoA Reductases - genetics | Type 2 diabetes | Genetic research | Enzymes | Thiols | Diabetes | Low density lipoprotein | Statins | Cholesterol | Risk factors
Internal Medicine | LDL CHOLESTEROL | HIGH-DOSE ATORVASTATIN | METAANALYSIS | STATIN THERAPY | ASSOCIATION ANALYSES | DISEASE | PREVENTION | BODY-MASS INDEX | RISK | MENDELIAN RANDOMIZATION | MEDICINE, GENERAL & INTERNAL | Body Mass Index | Genetic Testing | Cholesterol, HDL - metabolism | Diabetes Mellitus, Type 2 - genetics | Humans | Middle Aged | Risk Factors | Male | Body Weight - genetics | Randomized Controlled Trials as Topic | Hydroxymethylglutaryl-CoA Reductase Inhibitors - adverse effects | Cholesterol, LDL - metabolism | Polymorphism, Single Nucleotide - genetics | Female | Aged | Hydroxymethylglutaryl CoA Reductases - genetics | Type 2 diabetes | Genetic research | Enzymes | Thiols | Diabetes | Low density lipoprotein | Statins | Cholesterol | Risk factors
Journal Article
Journal of Heart and Lung Transplantation, ISSN 1053-2498, 2010, Volume 29, Issue 5, pp. 523 - 530
Background Nebulized amphotericin B deoxycholate (n-ABD) is used to prevent Aspergillus infection in lung transplantation. Nebulized liposomal amphotericin B...
Surgery | nebulized prophylaxis | transplantation infection | aspergillus infection | lung transplantation | amphotericin B | aspergillus supp | fungal prophylaxis | CARDIAC & CARDIOVASCULAR SYSTEMS | RISK-FACTORS | LIPID COMPLEX | SAFETY | DEOXYCHOLATE | ANTIFUNGAL PROPHYLAXIS | CYTOMEGALOVIRUS-INFECTION | RECIPIENTS | FUNGAL-INFECTIONS | TRANSPLANTATION | SCEDOSPORIUM | INVASIVE ASPERGILLOSIS | RESPIRATORY SYSTEM | Antifungal Agents - adverse effects | Drug Administration Schedule | Pulmonary Aspergillosis - prevention & control | Humans | Immunosuppressive Agents - therapeutic use | Middle Aged | Administration, Inhalation | Male | Opportunistic Infections - prevention & control | Feasibility Studies | Amphotericin B - adverse effects | Dose-Response Relationship, Drug | Deoxycholic Acid - adverse effects | Lung Transplantation - immunology | Amphotericin B - administration & dosage | Adult | Female | Immunosuppressive Agents - adverse effects | Deoxycholic Acid - administration & dosage | Liposomes | Drug Therapy, Combination | Antifungal Agents - administration & dosage | Drug Combinations | Cohort Studies
Surgery | nebulized prophylaxis | transplantation infection | aspergillus infection | lung transplantation | amphotericin B | aspergillus supp | fungal prophylaxis | CARDIAC & CARDIOVASCULAR SYSTEMS | RISK-FACTORS | LIPID COMPLEX | SAFETY | DEOXYCHOLATE | ANTIFUNGAL PROPHYLAXIS | CYTOMEGALOVIRUS-INFECTION | RECIPIENTS | FUNGAL-INFECTIONS | TRANSPLANTATION | SCEDOSPORIUM | INVASIVE ASPERGILLOSIS | RESPIRATORY SYSTEM | Antifungal Agents - adverse effects | Drug Administration Schedule | Pulmonary Aspergillosis - prevention & control | Humans | Immunosuppressive Agents - therapeutic use | Middle Aged | Administration, Inhalation | Male | Opportunistic Infections - prevention & control | Feasibility Studies | Amphotericin B - adverse effects | Dose-Response Relationship, Drug | Deoxycholic Acid - adverse effects | Lung Transplantation - immunology | Amphotericin B - administration & dosage | Adult | Female | Immunosuppressive Agents - adverse effects | Deoxycholic Acid - administration & dosage | Liposomes | Drug Therapy, Combination | Antifungal Agents - administration & dosage | Drug Combinations | Cohort Studies
Journal Article
Journal of the American College of Cardiology, ISSN 0735-1097, 07/2017, Volume 70, Issue 1, pp. 1 - 25
Abstract Background The burden of cardiovascular diseases (CVDs) remains unclear in many regions of the world. Objectives The GBD (Global Burden of Disease)...
Cardiovascular | Internal Medicine | global health | epidemiology | cause of death | SYSTEMATIC ANALYSIS | LOW-INCOME COUNTRIES | RISK-FACTORS | CAUSE-SPECIFIC MORTALITY | DISABILITY WEIGHTS | PREVALENCE | DEATHS | AMERICAN-HEART-ASSOCIATION | PERIPHERAL ARTERIAL-DISEASE | HYPERTENSION | CARDIAC & CARDIOVASCULAR SYSTEMS | COUNTRIES | PREVENTION | TRANSITION | Morbidity - trends | Risk Assessment - methods | Prevalence | Prospective Studies | Survival Rate - trends | Global Health | Humans | Middle Aged | Risk Factors | Male | Life Expectancy - trends | Young Adult | Cardiovascular Diseases - epidemiology | Sex Distribution | Adult | Cause of Death - trends | Female | Aged | Retrospective Studies | Cardiovascular diseases | Analysis | Heart | Stroke | Life expectancy | Health | Mortality | Cardiovascular disease | Epidemiology | Coronary artery disease | Diseases | Life span | Ischemia | Autopsy | Fatalities | Death | Health risk assessment | Heart diseases | Age | Public health | CVD, cardiovascular disease | IHD, ischemic heart disease | PAD, peripheral arterial disease | RHD, rheumatic heart disease | YLD, years lived with disability | YLL, years of life lost | SDI, sociodemographic index | DALY, disability-adjusted life-year | UI, uncertainty interval | Original Investigation | Medical and Health Sciences | Medicin och hälsovetenskap | Public Health, Global Health, Social Medicine and Epidemiology | Hälsovetenskaper | Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi | Health Sciences
Cardiovascular | Internal Medicine | global health | epidemiology | cause of death | SYSTEMATIC ANALYSIS | LOW-INCOME COUNTRIES | RISK-FACTORS | CAUSE-SPECIFIC MORTALITY | DISABILITY WEIGHTS | PREVALENCE | DEATHS | AMERICAN-HEART-ASSOCIATION | PERIPHERAL ARTERIAL-DISEASE | HYPERTENSION | CARDIAC & CARDIOVASCULAR SYSTEMS | COUNTRIES | PREVENTION | TRANSITION | Morbidity - trends | Risk Assessment - methods | Prevalence | Prospective Studies | Survival Rate - trends | Global Health | Humans | Middle Aged | Risk Factors | Male | Life Expectancy - trends | Young Adult | Cardiovascular Diseases - epidemiology | Sex Distribution | Adult | Cause of Death - trends | Female | Aged | Retrospective Studies | Cardiovascular diseases | Analysis | Heart | Stroke | Life expectancy | Health | Mortality | Cardiovascular disease | Epidemiology | Coronary artery disease | Diseases | Life span | Ischemia | Autopsy | Fatalities | Death | Health risk assessment | Heart diseases | Age | Public health | CVD, cardiovascular disease | IHD, ischemic heart disease | PAD, peripheral arterial disease | RHD, rheumatic heart disease | YLD, years lived with disability | YLL, years of life lost | SDI, sociodemographic index | DALY, disability-adjusted life-year | UI, uncertainty interval | Original Investigation | Medical and Health Sciences | Medicin och hälsovetenskap | Public Health, Global Health, Social Medicine and Epidemiology | Hälsovetenskaper | Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi | Health Sciences
Journal Article