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1. Full Text Reply to "Comments on Fouchier's calculation of risk and elapsed time for escape of a laboratory-acquired infection from his laboratory"
by Fouchier, Ron
mBio, ISSN 2161-2129, 01/2015, Volume 6, Issue 2
FERRETS | MICROBIOLOGY | A/H5N1 VIRUS | RESPIRATORY DROPLET | AIRBORNE TRANSMISSION | Middle East Respiratory Syndrome Coronavirus - pathogenicity | Pandemics - prevention & control | Influenza A virus - pathogenicity | Biomedical Research - methods | Biomedical Research - trends | Virus Diseases - virology | SARS Virus - pathogenicity
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2. Full Text Role of receptor binding specificity in influenza A virus transmission and pathogenesis
by Graaf, Miranda and Fouchier, Ron A M
The EMBO Journal, ISSN 0261-4189, 04/2014, Volume 33, Issue 8, pp. 823 - 841
The recent emergence of a novel avian A/H7N9 influenza virus in poultry and humans in China, as well as laboratory studies on adaptation and transmission of... 
A/H5N1 influenza virus | airborne transmission | pathogenesis | receptor binding specificity | A/H7N9 influenza virus | AIRWAY EPITHELIAL-CELLS | SINGLE AMINO-ACID | HUMAN INFECTION | H7N9 VIRUS | BIOCHEMISTRY & MOLECULAR BIOLOGY | LOWER RESPIRATORY-TRACT | SIALIC-ACID RECEPTOR | HONG-KONG | CELL BIOLOGY | TO-PERSON TRANSMISSION | H5N1 VIRUSES | MOLECULAR-BASIS | Influenza A virus - physiology | Receptors, Virus - metabolism | Humans | Sialic Acids - metabolism | Adaptation, Biological | Substrate Specificity | Influenza, Human - transmission | Hemagglutinin Glycoproteins, Influenza Virus - metabolism | Polysaccharides - metabolism | Zoonoses - transmission | Zoonoses - virology | Animals | Virus Attachment | Protein Binding | Influenza, Human - virology | Viral Tropism | Viruses | Pandemics | Pathogenesis | Avian flu | H7N9 influenza virus | Reviews | Microbiology, Virology & Host Pathogen Interaction | Review | H5N1 influenza virus
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3. Full Text Airborne Transmission of Influenza A/H5N1 Virus Between Ferrets
by Sander Herfst and Eefje J. A. Schrauwen and Martin Linster and Salin Chutinimitkul and Emmie de Wit and Vincent J. Munster and Erin M. Sorrell and Theo M. Bestebroer and David F. Burke and Derek J. Smith and Guus F. Rimmelzwaan and Albert D. M. E. Osterhaus and Ron A. M. Fouchier
Science, ISSN 0036-8075, 6/2012, Volume 336, Issue 6088, pp. 1534 - 1541
Highly pathogenic avian influenza A/H5N1 virus can cause morbidity and mortality in humans but thus far has not acquired the ability to be transmitted by... 
Receptors | Inoculation | Experimental infection | Disease transmission | Pandemics | REPORTS | Viruses | Orthomyxoviridae | Ferrets | Genetic mutation | Amino acid substitution | A VIRUS | TO-PERSON TRANSMISSION | MEDIATED SELECTION | H5N1 VIRUS | HEMAGGLUTININ | MULTIDISCIPLINARY SCIENCES | HOST | INFECTION | MODEL | RECEPTOR SPECIFICITY | PATHOGENIC AVIAN INFLUENZA | Immune Sera | Reassortant Viruses - pathogenicity | Influenza A Virus, H5N1 Subtype - physiology | Poultry | Receptors, Virus - metabolism | Air Microbiology | Humans | Virulence | Molecular Sequence Data | Influenza A Virus, H5N1 Subtype - genetics | Virus Shedding | Hemagglutinin Glycoproteins, Influenza Virus - immunology | Hemagglutinin Glycoproteins, Influenza Virus - genetics | Respiratory System - virology | Female | Influenza, Human - virology | Oseltamivir - pharmacology | Disease Models, Animal | Hemagglutinin Glycoproteins, Influenza Virus - chemistry | Reverse Genetics | Antiviral Agents - pharmacology | Mutagenesis, Site-Directed | RNA Replicase - genetics | Viral Proteins - chemistry | Sialic Acids - metabolism | Viral Proteins - genetics | Influenza, Human - epidemiology | Containment of Biohazards | Influenza A Virus, H5N1 Subtype - drug effects | Influenza in Birds - epidemiology | Influenza, Human - transmission | Hemagglutinin Glycoproteins, Influenza Virus - metabolism | Animals | Orthomyxoviridae Infections - transmission | Virus Replication | RNA Replicase - chemistry | Influenza in Birds - virology | Influenza A Virus, H5N1 Subtype - pathogenicity | Mutation | Serial Passage | Orthomyxoviridae Infections - virology | Amino Acid Substitution | Avian influenza | Diseases and pests | Physiological aspects | Development and progression | Research | Animal diseases | Amino acids | Avian flu | Small mammals | Index Medicus | Polymerase | Human | Proteins | Influenza | Droplets | Genetic modification
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4. Full Text How a virus travels the world
by Verhagen, Josanne H and Herfst, Sander and Fouchier, Ron A.M
Science, ISSN 0036-8075, 02/2015, Volume 347, Issue 6222, pp. 616 - 617
  In November and December 2014, highly pathogenic avian influenza (HPAI) viruses of the H5 subtype originating from China were detected in poultry and wild... 
FERRETS | TRANSMISSION | H5N5 | CHINA | MULTIDISCIPLINARY SCIENCES | AVIAN INFLUENZA-VIRUSES | Pathogens | Viruses | Disease transmission | Avian flu | Public health | Animals | Poultry | Health | Influenza | Biological Sciences | Naturvetenskap | Natural Sciences | Zoonotic Ecology | Zoonotisk ekologi | Biologiska vetenskaper
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5. Full Text Substitutions Near the Receptor Binding Site Determine Major Antigenic Change During Influenza Virus Evolution
by Björn F. Koel and David F. Burke and Theo M. Bestebroer and Stefan van der Vliet and Gerben C. M. Zondag and Gaby Vervaet and Eugene Skepner and Nicola S. Lewis and Monique I. J. Spronken and Colin A. Russell and Mikhail Y. Eropkin and Aeron C. Hurt and Ian G. Barr and Jan C. de Jong and Guus F. Rimmelzwaan and Albert D. M. E. Osterhaus and Ron A. M. Fouchier and Derek J. Smith
Science, ISSN 0036-8075, 11/2013, Volume 342, Issue 6161, pp. 976 - 979
The molecular basis of antigenic drift was determined for the hemagglutinin (HA) of human influenza A/H3N2 virus. From 1968 to 2003, antigenic change was... 
Phenotypes | Receptors | Reactivity | Influenza | REPORTS | Antibodies | Viruses | Amino acids | Orthomyxoviridae | Ferrets | Amino acid substitution | ANTIBODY | HEMAGGLUTININ | RECOGNITION | A VIRUSES | MULTIDISCIPLINARY SCIENCES | Antigens, Viral - immunology | Humans | Amino Acid Substitution - immunology | Amino Acid Substitution - genetics | Antigens, Viral - genetics | Binding Sites - genetics | Hemagglutinin Glycoproteins, Influenza Virus - immunology | Influenza A Virus, H3N2 Subtype - genetics | Mutation | Influenza A Virus, H3N2 Subtype - immunology | Evolution, Molecular | Hemagglutinin Glycoproteins, Influenza Virus - genetics | Influenza viruses | Physiological aspects | Host-parasite relationships | Research | Health aspects | Binding sites (Biochemistry) | Antigens | Evolutionary biology | Neurons | Binding sites | Immune systems | Evolution | Drift
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6. Full Text Role of receptor binding specificity in influenza A virus transmission and pathogenesis
by Graaf, Miranda and Fouchier, Ron A M
The EMBO Journal, ISSN 0261-4189, 07/2014, Volume 33, Issue 14, pp. 1614 - 1614
BIOCHEMISTRY & MOLECULAR BIOLOGY | CELL BIOLOGY | Corrigendum
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7. Full Text Reply to “Comments on Fouchier's Calculation of Risk and Elapsed Time for Escape of a Laboratory-Acquired Infection from His Laboratory”
by Fouchier, Ron A. M
mBio, ISSN 2150-7511, 05/2015, Volume 6, Issue 2
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8. Full Text Global Patterns of Influenza a Virus in Wild Birds
by Björn Olsen and Vincent J. Munster and Anders Wallensten and Jonas Waldenström and Albert D. M. E. Osterhaus and Ron A. M. Fouchier and Molekylär virologi and Linköpings universitet and Institutionen för klinisk och experimentell medicin and Hälsouniversitetet
Science, ISSN 0036-8075, 4/2006, Volume 312, Issue 5772, pp. 384 - 388
The outbreak of highly pathogenic avian influenza of the H5N1 subtype in Asia, which has subsequently spread to Russia, the Middle East, Europe, and Africa,... 
Seasonal migration | Wild birds | Waterfowl | Influenza A virus | Viruses | Orthomyxoviridae | Review | H5N1 subtype influenza A virus | Ducks | Geese | Aviculture | TRANSMISSION | ASIA | AVIAN INFLUENZA | AQUATIC BIRDS | MULTIDISCIPLINARY SCIENCES | GENES | HIGHLY PATHOGENIC H5N1 | ECOLOGY | HONG-KONG | NORTH-AMERICA | DUCKS | Prevalence | Poultry | Influenza A virus - genetics | Birds - virology | Animals, Wild - virology | Influenza in Birds - transmission | Influenza A virus - isolation & purification | Influenza in Birds - epidemiology | Phylogeny | Birds - physiology | Influenza A Virus, H5N1 Subtype - isolation & purification | Genetic Variation | Animals | Influenza in Birds - virology | Reassortant Viruses | Disease Outbreaks - veterinary | Influenza A virus - pathogenicity | Animal Migration | Influenza A Virus, H5N1 Subtype - pathogenicity | Agriculture | Disease Reservoirs | Influenza A virus - classification | Animals, Wild - physiology | Migratory birds | Research | Health aspects | Analysis | Influenza research | Medical and Health Sciences | MEDICINE | Medicin och hälsovetenskap | MEDICIN
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9. Full Text Antigenic and Genetic Characteristics of Swine-Origin 2009 A(H1N1) Influenza Viruses Circulating in Humans
by Rebecca J. Garten and C. Todd Davis and Colin A. Russell and Bo Shu and Stephen Lindstrom and Amanda Balish and Wendy M. Sessions and Xiyan Xu and Eugene Skepner and Varough Deyde and Margaret Okomo-Adhiambo and Larisa Gubareva and John Barnes and Catherine B. Smith and Shannon L. Emery and Michael J. Hillman and Pierre Rivailler and James Smagala and Miranda de Graaf and David F. Burke and Ron A. M. Fouchier and Claudia Pappas and Celia M. Alpuche-Aranda and Hugo López-Gatell and Hiram Olivera and Irma López and Christopher A. Myers and Dennis Faix and Patrick J. Blair and Cindy Yu and Kimberly M. Keene and P. David Dotson and David Boxrud and Anthony R. Sambol and Syed H. Abid and Kirsten St. George and Tammy Bannerman and Amanda L. Moore and David J. Stringer and Patricia Blevins and Gail J. Demmler-Harrison and Michele Ginsberg and Paula Kriner and Steve Waterman and Sandra Smole and Hugo F. Guevara and Edward A. Belongia and Patricia A. Clark and Sara T. Beatrice and Ruben Donis and Jacqueline Katz and Lyn Finelli and Carolyn B. Bridges and Michael Shaw and Daniel B. Jernigan and Timothy M. Uyeki and Derek J. Smith and Alexander I. Klimov and Nancy J. Cox
Science, ISSN 0036-8075, 7/2009, Volume 325, Issue 5937, pp. 197 - 201
Since its identification in April 2009, an A(H1N1) virus containing a unique combination of gene segments from both North American and Eurasian swine lineages... 
H1N1 subtype influenza A virus | Maps | Pandemics | Influenza A virus | Swine | Environmental laboratories | Viruses | Orthomyxoviridae | Reports | Genomes | Public health | A VIRUS | UNITED-STATES | PIGS | TRANSMISSION | EVOLUTION | PATHOGENICITY | PHYLOGENETIC ANALYSIS | MULTIDISCIPLINARY SCIENCES | INFECTION | EMERGENCE | NORTH-AMERICA | Influenza A Virus, H1N1 Subtype - immunology | Viral Matrix Proteins - genetics | Influenza A Virus, H1N1 Subtype - classification | Swine Diseases - virology | Humans | Influenza A virus - genetics | Neuraminidase - genetics | Reassortant Viruses - genetics | Antigens, Viral - genetics | Hemagglutinin Glycoproteins, Influenza Virus - immunology | Influenza A Virus, H3N2 Subtype - genetics | Phylogeny | Hemagglutinin Glycoproteins, Influenza Virus - genetics | Genetic Variation | Hemagglutination Inhibition Tests | Influenza A Virus, H1N1 Subtype - isolation & purification | Disease Outbreaks | Genes, Viral | Influenza, Human - virology | Influenza A Virus, H1N1 Subtype - genetics | Genome, Viral | Hemagglutinin Glycoproteins, Influenza Virus - chemistry | Orthomyxoviridae Infections - veterinary | Viral Nonstructural Proteins - genetics | Influenza, Human - epidemiology | Antigens, Viral - immunology | Animals | Antibodies, Viral - immunology | Mutation | Orthomyxoviridae Infections - virology | Evolution, Molecular | Influenza, Human - immunology | Influenza viruses | Genetic aspects | Research | Health aspects | Swine influenza
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10. Full Text Pathogenesis and Transmission of Swine-Origin 2009 A(H1N1) Influenza Virus in Ferrets
by Vincent J. Munster and Emmie de Wit and Judith M. A. van den Brand and Sander Herfst and Eefje J. A. Schrauwen and Theo M. Bestebroer and David van de Vijver and Charles A. Boucher and Marion Koopmans and Guus F. Rimmelzwaan and Thijs Kuiken and Albert D. M. E. Osterhaus and Ron A. M. Fouchier
Science, ISSN 0036-8075, 7/2009, Volume 325, Issue 5939, pp. 481 - 483
The swine-origin A(H1N1) influenza virus that has emerged in humans in early 2009 has raised concerns about pandemic developments. In a ferret pathogenesis and... 
Inoculation | Throat | Disease transmission | Lungs | Aerosols | Viruses | Orthomyxoviridae | Reports | Infections | Ferrets | Trachea | A VIRUS | H5N1 VIRUSES | HUMANS | VIRULENCE | MULTIDISCIPLINARY SCIENCES | MAMMALS | Bronchi - virology | Influenza, Human - pathology | Humans | Orthomyxoviridae Infections - pathology | Child, Preschool | Influenza A Virus, H1N1 Subtype - pathogenicity | Virus Shedding | Influenza, Human - transmission | Trachea - virology | Respiratory System - virology | Animals | Orthomyxoviridae Infections - transmission | Virus Replication | Female | Influenza, Human - virology | Seasons | Orthomyxoviridae Infections - virology | Swine - virology | Disease Models, Animal | Development and progression | Genetic aspects | Swine influenza | Animal diseases | Pathology | Mammals | Swine flu
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11. Full Text Pathogenesis of influenza-induced acute respiratory distress syndrome
by Short, Kirsty R, PhD and Kroeze, Edwin J B Veldhuis, DVM and Fouchier, Ron A M, Prof and Kuiken, Thijs, Prof
Lancet Infectious Diseases, The, ISSN 1473-3099, 2014, Volume 14, Issue 1, pp. 57 - 69
Summary Acute respiratory distress syndrome (ARDS) is a fatal complication of influenza infection. In this Review we provide an integrated model for its... 
Infectious Disease | INFECTIOUS DISEASES | TUMOR-NECROSIS-FACTOR | DOUBLE-STRANDED-RNA | CYTOKINE RESPONSES | ALVEOLAR EPITHELIAL-CELLS | AVIAN INFLUENZA | PANDEMIC INFLUENZA | HUMAN MACROPHAGES | ENDOTHELIAL-CELLS | VIRUS-INDUCED PNEUMONIA | A H5N1 VIRUSES | Respiratory Distress Syndrome, Adult - pathology | Epithelial Cells - physiology | Immune System - physiology | Immune System - physiopathology | Respiratory Distress Syndrome, Adult - physiopathology | Epithelial Cells - virology | Humans | Epithelial Cells - pathology | Influenza, Human - complications | Endothelial Cells - pathology | Endothelial Cells - physiology | Acute respiratory distress syndrome | Respiratory distress syndrome | Health aspects | Analysis | Nitric oxide | Influenza | Influenza viruses | Endothelium
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12. Full Text The Potential for Respiratory Droplet-Transmissible A/H5N1 Influenza Virus to Evolve in a Mammalian Host
by Colin A. Russell and Judith M. Fonville and André E. X. Brown and David F. Burke and David L. Smith and Sarah L. James and Sander Herfst and Sander van Boheemen and Martin Linster and Eefje J. Schrauwen and Leah Katzelnick and Ana Mosterín and Thijs Kuiken and Eileen Maher and Gabriele Neumann and Albert D. M. E. Osterhaus and Yoshihiro Kawaoka and Ron A. M. Fouchier and Derek J. Smith
Science, ISSN 0036-8075, 6/2012, Volume 336, Issue 6088, pp. 1541 - 1547
Avian A/H5N1 influenza viruses pose a pandemic threat. As few as five amino acid substitutions, or four with reassortaient, might be sufficient for... 
Disease transmission | Surveillance | Virions | REPORTS | Viruses | Orthomyxoviridae | Infections | Nucleotides | Genetic mutation | Sequencing | Amino acid substitution | DYNAMICS | H5N1 | REPLICATION | MODEL | A VIRUSES | MULTIDISCIPLINARY SCIENCES | Adaptation, Physiological | Receptors, Virus - metabolism | Air Microbiology | Humans | Influenza A Virus, H5N1 Subtype - genetics | Hemagglutinin Glycoproteins, Influenza Virus - genetics | Respiratory System - virology | Influenza, Human - virology | RNA Replicase - genetics | Selection, Genetic | Sialic Acids - metabolism | Probability | Viral Proteins - genetics | Birds | Glycosylation | Influenza, Human - transmission | Mammals | Hemagglutinin Glycoproteins, Influenza Virus - metabolism | Animals | Genetic Fitness | Orthomyxoviridae Infections - transmission | Models, Biological | Influenza in Birds - virology | Influenza A Virus, H5N1 Subtype - pathogenicity | High-Throughput Nucleotide Sequencing | Mutation | Orthomyxoviridae Infections - virology | Amino Acid Substitution | Evolution, Molecular | Influenza, Human - immunology | Avian influenza | Physiological aspects | Development and progression | Research | Epidemiology | Amino acids | Evolution | Avian flu | Influenza | Circulating | Mathematical models | Droplets
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