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1. Full Text Microglial activation in normal-appearing brain regions of patients with cerebral glioma: a cross-sectional study
by Su, Zhangjie, Dr and Roncaroli, Federico, MD and Hinz, Rainer, PhD and Karabatsou, Konstantina, MD and Coope, David, PhD and Turkheimer, Federico, PhD and Jenkinson, Michael, PhD and Jackson, Alan, PhD and Herholz, Karl, MD and Gerhard, Alexander, MD
Lancet, The, ISSN 0140-6736, 2017, Volume 389, pp. S92 - S92
Abstract Background Translocator protein (TSPO) is overexpressed mainly in activated microglia under disease conditions. [11 C]-(R)PK11195 is a radioligand for... 
Internal Medicine | MEDICINE, GENERAL & INTERNAL | Medicine, Experimental | Medical research | Pets | Brain | Gliomas | Brain tumors | Analysis | Epilepsy
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2. Full Text High durability fuel cell cathodes obtained from cobalt metal organic frameworks
by Díaz-Duran, Ana Katherine and Viva, Federico A and Roncaroli, Federico
Electrochimica Acta, ISSN 0013-4686, 10/2019, Volume 320, p. 134623
Mesoporous carbons doped with Nitrogen and Cobalt were obtained from the pyrolysis of two different Cobalt Metal-Organic Frameworks (MOFs, ZIF-67 and CoNic)... 
Metal organic framework | Polymer electrolyte membrane | Non-noble catalyst | Platinum-free | Coordination polymer | Fuel cell | HIGH-PERFORMANCE | ELECTROCHEMISTRY | CARBON | ACTIVE-SITES | OXYGEN REDUCTION REACTION | IRON | INSIGHT | ELECTROCATALYSTS | CATALYTIC SITES | Coordination polymers | Pyrolysis | Parameters | Catalysts | Cell cathodes | Carbon dioxide | Dehydration | Nitrogen | Cobalt | Maximum power density | Platinum | Fuel cells | X ray photoelectron spectroscopy | Catalysis | Polymers | Metal-organic frameworks | Proton exchange membrane fuel cells
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3. Full Text Co,N-doped mesoporous carbons cobalt derived from coordination polymer as supercapacitors
by Díaz-Duran, Ana Katherine and Montiel, Gonzalo and Viva, Federico A and Roncaroli, Federico
Electrochimica Acta, ISSN 0013-4686, 03/2019, Volume 299, pp. 987 - 998
In order to obtain new materials for energy storage as supercapacitors, Cobalt Nitrogen doped mesoporous carbons were prepared from pyrolysis of two Cobalt... 
Supercapacitor | Metal-organic framework | Coordination polymer | Cobalt | Pseudocapacitance | ELECTROCHEMISTRY | ELECTRODE MATERIALS | NANOPOROUS CARBON | PERFORMANCE SUPERCAPACITORS | ZEOLITIC IMIDAZOLATE FRAMEWORKS | METAL-ORGANIC FRAMEWORKS | OXYGEN REDUCTION | HOLLOW SPHERES | NITROGEN | DOPED POROUS CARBON | ENERGY-STORAGE | Pyrolysis | Polymer industry | Polymers | Capacitors | Leaching | Coordination polymers | Supercapacitors | Light emitting diodes | Acid leaching | Capacitance | Coordination compounds | Metal-organic frameworks | Energy storage
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4. Full Text Reference and Target Region Modeling of [11C]-(R)-PK11195 Brain Studies
by Turkheimer, Federico E and Edison, Paul and Pavese, Nicola and Roncaroli, Federico and Anderson, Alexander N and Hammers, Alexander and Gerhard, Alexander and Hinz, Rainer and Tai, Yan F and Brooks, David J
The Journal of Nuclear Medicine, ISSN 0161-5505, 01/2007, Volume 48, Issue 1, pp. 158 - 167
PET with [C-11]-(R)-PK11195 is currently the modality of choice for the in vivo imaging of microglial activation in the human brain. In this work we devised a... 
Supervised clustering | PK11195 | PET | Microglia | supervised clustering | MICROGLIAL ACTIVATION | RECEPTOR | CNS | HUNTINGTON-DISEASE | POSITRON-EMISSION-TOMOGRAPHY | IN-VIVO | SPECTRAL-ANALYSIS | microglia | BINDING | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | Humans | Carbon Radioisotopes - therapeutic use | Image Interpretation, Computer-Assisted | Antineoplastic Agents - therapeutic use | Models, Statistical | Positron-Emission Tomography - methods | Huntington Disease - radiotherapy | Case-Control Studies | Algorithms | Time Factors | Brain - pathology | Isoquinolines - therapeutic use | Kinetics | Pattern Recognition, Automated | Huntington Disease - drug therapy | Cluster Analysis | Cluster analysis | Studies | Plasma | Brain | Parameter estimation | Parkinsons disease | Nervous system | Pituitary gland | Models
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5. Full Text [11C]-(R)PK11195 tracer kinetics in the brain of glioma patients and a comparison of two referencing approaches
by Su, Zhangjie and Herholz, Karl and Gerhard, Alexander and Roncaroli, Federico and Du Plessis, Daniel and Jackson, Alan and Turkheimer, Federico and Hinz, Rainer
European Journal of Nuclear Medicine and Molecular Imaging, ISSN 1619-7070, 9/2013, Volume 40, Issue 9, pp. 1406 - 1419
Translocator protein (TSPO) is a biomarker of neuroinflammation that can be imaged by PET using [11C]-(R)PK11195. We sought to characterize the... 
Medicine & Public Health | Glioma | Orthopedics | Translocator protein | Oncology | Reference tissue | Kinetic analysis | Nuclear Medicine | Imaging / Radiology | Cardiology | [ 11 C]-( R )PK11195 | PET | C]-(R)PK11195 | REFERENCE REGION MODEL | HUMAN ASTROCYTOMAS | MICROGLIAL ACTIVATION | ALZHEIMERS-DISEASE | RECEPTOR | BENZODIAZEPINE BINDING-SITES | PROTEIN 18 KDA | IN-VIVO | [C-11]-(R)PK11195 | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | PLASMA INPUT | Radiopharmaceuticals - pharmacokinetics | Isoquinolines - pharmacokinetics | Receptors, GABA - genetics | Brain Neoplasms - diagnostic imaging | Brain Neoplasms - metabolism | Case-Control Studies | Glioma - metabolism | Tissue Distribution | Reference Standards | Glioma - diagnostic imaging | Amides - pharmacokinetics | Positron-Emission Tomography - standards | Receptors, GABA - metabolism | Protein Binding | Tracers (Biology) | Comparative analysis | Gliomas | Brain tumors | Brain | Kinetics | Patients | Cancer | [11C]-(R)PK11195 | Original
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6. Full Text MOF derived Mesoporous Nitrogen doped Carbons with high Activity towards Oxygen Reduction
by Díaz-Duran, Ana Katherine and Roncaroli, Federico
Electrochimica Acta, ISSN 0013-4686, 10/2017, Volume 251, pp. 638 - 650
In order to obtain Platinum-free catalysts for the Oxygen Reduction Reaction (ORR) in Fuel Cells, Nitrogen doped mesoporous carbons were prepared from... 
metal organic framework | fuel cell | Platinum-free | non-noble catalyst | coordination polymer | polymer electrolyte membrane | ELECTROCHEMISTRY | CRYSTAL-STRUCTURES | N-C CATALYSTS | ELECTROCATALYSTS | METAL-ORGANIC FRAMEWORKS | MEMBRANE FUEL-CELLS | SITES | FE/N/C CATALYSTS | MAGNETIC-PROPERTIES | COORDINATION POLYMERS | COBALT | Polymers | Pyrolysis | Fuel cells | Exchanging | Coordination polymers | Hydrogen peroxide | Catalysts | Photomicrographs | Electrokinetics | Electron micrographs | Nitrogen | Cobalt | Platinum | Methyl alcohol | Electrolytes | Catalysis | Coordination compounds | Metal-organic frameworks | Bars
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7. Full Text The neuropathological basis of clinical progression in multiple sclerosis
by Reynolds, Richard and Roncaroli, Federico and Nicholas, Richard and Radotra, Bishan and Gveric, Djordje and Howell, Owain
Acta Neuropathologica, ISSN 0001-6322, 8/2011, Volume 122, Issue 2, pp. 155 - 170
Multiple sclerosis is the major inflammatory condition affecting the central nervous system (CNS) and is characterised by disseminated focal immune-mediated... 
Pathology | Neurosciences | Medicine & Public Health | Demyelination | Neurodegeneration | Axon loss | Inflammation | Clinical progression | Remyelination | LONG-TERM DISABILITY | AXONAL DAMAGE | MRI | SPINAL-CORD | PATHOLOGY | NATURAL-HISTORY | CORTICAL-LESIONS | NEUROSCIENCES | CD8(+) T-CELLS | CLINICAL NEUROLOGY | APPEARING WHITE-MATTER | BENIGN FORM | Inflammation - pathology | Humans | Brain - pathology | Multiple Sclerosis - pathology | Demyelinating Diseases - pathology | Disease Progression | Nerve Degeneration - pathology | Development and progression | Multiple sclerosis | Universities and colleges
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8. Full Text Chromosomal profiles of gene expression in Huntington's disease
by Anderson, Alexander N and Roncaroli, Federico and Hodges, Angela and Deprez, Manuel and Turkheimer, Federico E
Brain, ISSN 0006-8950, 2/2008, Volume 131, Issue 2, pp. 381 - 388
Recent studies suggested that Huntington's disease is due to aberrant interactions between mutant huntingtin protein, transcription factors and transcriptional... 
Histone deacetylase | Chromosomal expression | Huntington's disease | Microarrays | Chromowave | chromosomal expression | HISTONE DEACETYLASE INHIBITORS | histone deacetylase | NEUROSCIENCES | ONSET | BRAIN | CLINICAL NEUROLOGY | microarrays | AGE | Data Interpretation, Statistical | Oligonucleotide Array Sequence Analysis - methods | Humans | Gene Expression Regulation | Male | Huntington Disease - metabolism | Nerve Tissue Proteins - genetics | Disease Progression | Caudate Nucleus - metabolism | Huntingtin Protein | Chromosome Aberrations | Huntington Disease - genetics | Female | Huntington Disease - blood | Transcription, Genetic | Mutation | Nuclear Proteins - genetics
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9. Full Text Kinetic modelling of [11C]PBR28 for 18 kDa translocator protein PET data: A validation study of vascular modelling in the brain using XBD173 and tissue analysis
by Veronese, Mattia and Reis Marques, Tiago and Bloomfield, Peter S and Rizzo, Gaia and Singh, Nisha and Jones, Deborah and Agushi, Erjon and Mosses, Dominic and Bertoldo, Alessandra and Howes, Oliver and Roncaroli, Federico and Turkheimer, Federico E
Journal of Cerebral Blood Flow & Metabolism, ISSN 0271-678X, 7/2018, Volume 38, Issue 7, pp. 1227 - 1242
The 18 kDa translocator protein (TSPO) is a marker of microglia activation in the central nervous system and represents the main target of radiotracers for the... 
endothelium | kinetic modelling | 3D modelling | C]PBR28 | TSPO | immunohistochemistry | XBD173 | [11C]PBR28 | Original
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10. Full Text New features in the redox coordination chemistry of metal nitrosyls {M-NO+; M-NO{radical dot}; M-NO-(HNO)}
by Roncaroli, Federico and Videla, Mariela and Slep, Leonardo D and Olabe, José A
Coordination Chemistry Reviews, ISSN 0010-8545, 07/2007, Volume 251, Issue 13-14, pp. 1903 - 1930
We describe new developments in the coordination chemistry of bound nitrosyl, considering its three formal redox states: NO , NO{radical dot} and NO /HNO. We... 
Electrophilic reactivity | Nitrosonium | Nitroxyl | Nitric oxide | Nucleophilic reactivity
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11. Full Text Cobalt and Iron Complexes with N-heterocyclic Ligands as Pyrolysis Precursors for Oxygen Reduction Catalysts
by Roncaroli, Federico and Dal Molin, Emiliano S and Viva, Federico A and Bruno, Mariano M and Halac, Emilia B
Electrochimica Acta, ISSN 0013-4686, 08/2015, Volume 174, Issue 1, pp. 66 - 77
Cobalt and Iron based catalysts for the Oxygen Reduction Reaction (ORR) are a promising alternative to the use of Pt in Polymer Electrolyte Fuel Cells (PEMFC).... 
fuel cell | Platinum-free | non-noble catalyst | ORR | polymer electrolyte membrane | Polymer electrolyte membrane | Non-noble catalyst | Fuel Cell | ELECTROCHEMISTRY | PYRIDINE | METAL-FREE ELECTROCATALYSTS | FE/N/C-CATALYSTS | POLYANILINE | FUEL | SITES | XPS | LITHIUM | Pyrolysis | Heterocyclic compounds
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12. Full Text The 18-kDa mitochondrial translocator protein in human gliomas: An 11 C-(R)PK11195 PET imaging and neuropathology study
by Su, Zhangjie and Roncaroli, Federico and Durrenberger, Pascal F and Coope, David J and Karabatsou, Konstantina and Hinz, Rainer and Thompson, Gerard and Turkheimer, Federico E and Janczar, Karolina and Plessis, Daniel Du and Brodbelt, Andrew and Jackson, Alan and Gerhard, Alexander and Herholz, Karl
Journal of Nuclear Medicine, ISSN 0161-5505, 04/2015, Volume 56, Issue 4, pp. 512 - 517
11 c-(r)pk11195 | Glioma | Translocator protein | PET | Microglia
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13. Full Text A painful swollen thigh in a diabetic patient: diabetic myonecrosis
by Ali, Omer, Dr and Narshi, Chetan, MRCP and Khanna, Monica, FRCR and Roncaroli, Federico, MD and Abraham, Sonya, PhD
Lancet, The, ISSN 0140-6736, 2014, Volume 383, Issue 9931, pp. 1860 - 1860
To link to full-text access for this article, visit this link: http://dx.doi.org/10.1016/S0140-6736(14)60543-2 Byline: Omer Ali, Chetan Narshi, Monica Khanna,... 
Internal Medicine | MEDICINE, GENERAL & INTERNAL | MUSCLE INFARCTION | Infarction - etiology | Humans | Thigh | Connective Tissue Diseases - diagnosis | Infarction - diagnosis | Connective Tissue Diseases - etiology | Edema - diagnosis | Edema - etiology | Magnetic Resonance Imaging | Necrosis - etiology | Adult | Female | Muscle, Skeletal - pathology | Necrosis - diagnosis | Diabetes Mellitus, Type 2 - complications | Muscle, Skeletal - blood supply | Muscles | Diagnosis | Necrosis | Ultrasonic imaging | Diabetes | Kinases | Biopsy | Thrombosis | Medical treatment
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14. Full Text A Gradient of neuronal loss and meningeal inflammation in multiple sclerosis
by Magliozzi, Roberta and Howell, Owain W and Reeves, Cheryl and Roncaroli, Federico and Nicholas, Richard and Serafini, Barbara and Aloisi, Francesca and Reynolds, Richard
Annals of Neurology, ISSN 0364-5134, 10/2010, Volume 68, Issue 4, pp. 477 - 493
Objective: Prominent inflammation with formation of ectopic B-cell follicle-like structures in the meninges in secondary progressive multiple sclerosis (MS)... 
CORTICAL DEMYELINATION | APPEARING WHITE-MATTER | CORD AXONAL LOSS | DISEASE | INFECTION | PATHOLOGY | NEUROSCIENCES | EPSTEIN-BARR-VIRUS | PLASMA-CELLS | CLINICAL NEUROLOGY | B-CELL FOLLICLES | DEGENERATION | Inflammation - pathology | Neurons - pathology | Neuroglia - pathology | Humans | Middle Aged | Astrocytes - pathology | Caspase 3 - metabolism | Cerebral Cortex - pathology | Myelin-Associated Glycoprotein - metabolism | Male | Phosphopyruvate Hydratase - metabolism | Antigens, CD - metabolism | Aged, 80 and over | Adult | Female | Nogo Proteins | B-Lymphocytes - pathology | B-Lymphocytes - metabolism | 3',5'-Cyclic-AMP Phosphodiesterases - metabolism | Meninges - pathology | Myelin-Oligodendrocyte Glycoprotein | In Situ Nick-End Labeling - methods | Inflammation - immunology | Inflammation - etiology | Multiple Sclerosis - complications | Analysis of Variance | Cell Death - physiology | Multiple Sclerosis - immunology | Multiple Sclerosis - pathology | Aged | Myelin Proteins - metabolism | Nitric Oxide Synthase Type II - metabolism
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15. Full Text Extensive grey matter pathology in the cerebellum in multiple sclerosis is linked to inflammation in the subarachnoid space
by Howell, Owain W and Schulz‐Trieglaff, Elena Katharina and Carassiti, Daniele and Gentleman, Steven M and Nicholas, Richard and Roncaroli, Federico and Reynolds, Richard
Neuropathology and Applied Neurobiology, ISSN 0305-1846, 10/2015, Volume 41, Issue 6, pp. 798 - 813
Cerebellar grey matter demyelination correlates with inflammation in the overlying meninges and grey matter microglial activation supporting the concept that... 
grey matter | meningeal inflammation | demyelination | multiple sclerosis | cerebellum | Cerebellum | Multiple sclerosis | Meningeal inflammation | Demyelination | Grey matter | CLINICALLY ISOLATED SYNDROME | PATHOLOGY | CEREBROSPINAL-FLUID | NATURAL-HISTORY | NEUROSCIENCES | LESIONS | CLINICAL NEUROLOGY | CORTICAL PATHOLOGY | DISEASE | GRAY-MATTER | B-CELL FOLLICLES | Neurons - pathology | Humans | Middle Aged | Encephalitis - pathology | Male | Cerebellum - pathology | Multiple Sclerosis - complications | Gray Matter - pathology | Subarachnoid Space - pathology | Aged, 80 and over | Multiple Sclerosis - pathology | Adult | Female | Aged | Encephalitis - complications | Brain | Inflammation | B cells | T cells | Analysis | Pathology
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16. Full Text Novel reference region model reveals increased microglial and reduced vascular binding of11C-(R)-PK11195 in patients with Alzheimer's disease
by Tomasi, Giampaolo and Edison, Paul and Bertoldo, Alessandra and Roncaroli, Federico and Singh, Poonam and Gerhard, Alexander and Cobelli, Claudio and Brooks, David J and Turkheimer, Federico E
Journal of Nuclear Medicine, ISSN 0161-5505, 08/2008, Volume 49, Issue 8, pp. 1249 - 1256
Simplified reference region modeling | Vascular fibrosis | C-(R)-PK11195 | Alzheimer's disease | PET