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Steroids, ISSN 0039-128X, 06/2019, p. 108428
Reproduction and energy balance are inextricably linked in order to optimize the evolutionary fitness of an organism. With insufficient or excessive energy... 
Journal Article
Neuroendocrinology, ISSN 0028-3835, 11/2015, Volume 102, Issue 3, pp. 184 - 193
  Kisspeptin is a neuropeptide that signals via a Gαq-coupled receptor, GPR54, in gonadotropin-releasing hormone (GnRH) neurons and is essential for pubertal... 
Journal Article
Journal of Comparative Neurology, ISSN 0021-9967, 07/2012, Volume 520, Issue 10, pp. 2143 - 2162
  Kisspeptin is essential for reproductive functions in humans. As a model for the human we have used the female guinea pig, which has a long ovulatory cycle... 
Journal Article
Endocrinology, ISSN 0013-7227, 09/2010, Volume 151, Issue 9, pp. 4477 - 4484
17β-Estradiol (E2) both inhibits and excites GnRH neurons via presynaptic as well as postsynaptic mechanisms. Although it has been demonstrated that E2 can... 
Journal Article
American Journal of Physiology, ISSN 0193-1849, 06/2013, Volume 304, Issue 11, p. E1237
  Kisspeptin signaling via its cognate receptor G protein-coupled receptor 54 (GPR54) in gonadotropin-releasing hormone (GnRH) neurons plays a critical role in... 
Signal transduction | Neurons | Glycoproteins | T cell receptors | Hormones | Kinases
Journal Article
Endocrinology, ISSN 0013-7227, 06/2012, Volume 153, Issue 6, p. 2933
Journal Article
Journal Article
Molecular and Cellular Endocrinology, ISSN 0303-7207, 03/2013, Volume 367, Issue 1-2, p. 85
a* Single-cell quantitative PCR of channel transcripts in GnRH neurons was validated and used. a* E2 increased or decreased the mRNA expression of ion channels... 
Neurosciences | Pituitary hormones | Messenger RNA | Neurons | Neurohormones | Phenols | Luteinizing hormone | Ion channels | Cyanides | Glycoproteins | Estradiol | Membrane proteins
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 01/2010, Volume 30, Issue 4, pp. 1560 - 1565
Leptin can exert its potent appetite-suppressing effects via activation of hypothalamic proopiomelanocortin (POMC) neurons. It depolarizes POMC neurons via... 
RECEPTOR POTENTIAL CHANNELS | PHOSPHOLIPASE-C-GAMMA | NEUROSCIENCES | BRAIN | CATION CHANNEL | Flufenamic Acid - pharmacology | TRPC Cation Channels - drug effects | Calcium Signaling - physiology | Leptin - metabolism | Lanthanum - pharmacology | Male | Neurons - cytology | Green Fluorescent Proteins - genetics | Phosphatidylinositol 3-Kinases - metabolism | Phosphatidylinositol 3-Kinases - antagonists & inhibitors | Ion Channel Gating - physiology | Janus Kinase 2 - metabolism | Female | Appetite - physiology | Leptin - pharmacology | Neurons - metabolism | Neurons - drug effects | TRPC Cation Channels - genetics | Janus Kinase 2 - antagonists & inhibitors | Organ Culture Techniques | Membrane Potentials - drug effects | Boron Compounds - pharmacology | Phospholipase C gamma - metabolism | Appetite - drug effects | Mice, Transgenic | Imidazoles - pharmacology | Calcium Channel Blockers - pharmacology | Membrane Potentials - physiology | Pro-Opiomelanocortin - metabolism | Patch-Clamp Techniques | Animals | Hypothalamus - metabolism | Hypothalamus - cytology | Signal Transduction - drug effects | Calcium Signaling - drug effects | Staining and Labeling | TRPC Cation Channels - metabolism | Signal Transduction - physiology | Mice | Phospholipase C gamma - antagonists & inhibitors | Ion Channel Gating - drug effects | Brief Communications
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 02/2017, Volume 114, Issue 9, pp. 2413 - 2418
Journal Article