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Journal of Neuroscience, ISSN 0270-6474, 09/2003, Volume 23, Issue 24, pp. 8608 - 8617
The specific mechanisms underlying general anesthesia are primarily unknown. The intravenous general anesthetic etomidate acts by potentiating GABA A... 
β2 subunit | GABA | Transgenic | General anesthesia | Sedation | Loreclezole | Etomidate | Cellular | loreclezole | etomidate | GABAA β2 subunit | transgenic | Molecular | general anesthesia | sedation
Journal Article
JOURNAL OF NEUROSCIENCE, ISSN 0270-6474, 09/2003, Volume 23, Issue 24, pp. 8608 - 8617
Journal Article
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, ISSN 1552-5260, 2016, Volume 12, Issue 7, pp. P845 - P845
Journal Article
Alzheimer's & Dementia, ISSN 1552-5260, 07/2016, Volume 12, pp. P845 - P845
Journal Article
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 02/2003, Volume 23, Issue 3, pp. 788 - 797
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 05/2001, Volume 21, Issue 10, pp. 3409 - 3418
The α1β2γ2 is the most abundant subtype of the GABA A receptor and is localized in many regions of the brain. To gain more insight into the role of this... 
Cerebellum | receptor | Mouse | Rotarod | Benzodiazepine | GABA | Radioligand | Inhibitory current | Locomotor activity | mouse | radioligand | ARTICLE | inhibitory current | locomotor activity | GABAA receptor | rotarod | cerebellum | benzodiazepine
Journal Article
PLoS ONE, ISSN 1932-6203, 2011, Volume 6, Issue 7, p. e21499
Journal Article
JOURNAL OF PHYSIOLOGY-LONDON, ISSN 0022-3751, 11/2002, Volume 545, Issue 1, pp. 169 - 181
Each GABA(A) receptor consists of two alpha and three other subunits. The spatial and temporal distribution of different alpha subunit isomeres expressed by... 
SUBTYPE | MESSENGER-RNAS | PHYSIOLOGY | A RECEPTOR | CORTICAL-NEURONS | AMINOBUTYRIC ACID(A) RECEPTORS | POSTSYNAPTIC CURRENTS | POSTNATAL-DEVELOPMENT | GRANULE CELLS | EXPRESSION | BRAIN
Journal Article
Journal Article
Neuropharmacology, ISSN 0028-3908, 07/2014, Volume 82, pp. 161 - 173
Previous work has suggested that activation of mGlu5 receptor augments NMDA receptor function and thereby may constitute a rational approach addressing... 
Schizophrenia | Positive allosteric modulator | Neurotoxicity | Metabotropic glutamate receptor | Antipsychotic activity | METABOTROPIC GLUTAMATE-RECEPTOR | PROTEIN-KINASE-C | NEGATIVE SYMPTOMS | FRAGILE-X | NEUROSCIENCES | PREFRONTAL CORTEX | D-SERINE | PHARMACOLOGY & PHARMACY | LONG-TERM POTENTIATION | BINDING-SITES | ACUTE STRESS | METHYL-D-ASPARTATE | Antipsychotic Agents - toxicity | Neurons - pathology | Cricetulus | Rats, Wistar | Benzamides - pharmacokinetics | Allosteric Regulation | Humans | Male | Excitatory Amino Acid Agents - pharmacokinetics | Mice, 129 Strain | Necrosis - pathology | Excitatory Amino Acid Agents - chemistry | Oxadiazoles - toxicity | Receptor, Metabotropic Glutamate 5 - genetics | Necrosis - physiopathology | Neurotoxicity Syndromes - pathology | Neurons - physiology | Female | Cell Death - drug effects | Neurons - drug effects | Oxadiazoles - chemistry | Oxadiazoles - pharmacokinetics | Benzamides - chemistry | CHO Cells | Benzamides - toxicity | Brain - physiopathology | Cells, Cultured | Antipsychotic Agents - pharmacokinetics | Receptor, Metabotropic Glutamate 5 - metabolism | Rats, Sprague-Dawley | Mice, Knockout | Brain - drug effects | Excitatory Amino Acid Agents - toxicity | Animals | Antipsychotic Agents - chemistry | Cell Death - physiology | Neurotoxicity Syndromes - physiopathology | Brain - pathology | Methyl aspartate | Antipsychotic drugs | Glutamate | Index Medicus
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 3/2004, Volume 101, Issue 10, pp. 3662 - 3667
The principal inhibitory neurotransmitter in the mammalian brain, γ-aminobutyric acid (GABA), is thought to regulate memory processes by activating transient... 
Brain | Biological Sciences | Receptors | Neurons | Memory | Inurement | Pharmacology | Mice | Electric current | Behavioral neuroscience | Hippocampus
Journal Article
Scientific reports, ISSN 2045-2322, 12/2019, Volume 9, Issue 1, pp. 19877 - 14
BACE1 is the first enzyme involved in APP processing, thus it is a strong therapeutic target candidate for Alzheimer's disease. The observation of deleterious... 
Journal Article
American Journal of Physiology - Endocrinology and Metabolism, ISSN 0193-1849, 09/2018, Volume 315, Issue 3, pp. E386 - E393
Fructose consumption in humans and animals has been linked to enhanced de novo lipogenesis, dyslipidemia, and insulin resistance. Hereditary deficiency of... 
OBESITY | PHYSIOLOGY | GLUCONEOGENESIS | GLUCOSE | LIPOGENESIS | DISEASE | ENDOCRINOLOGY & METABOLISM | HUMANS | BEVERAGES | GLUCOKINASE | EPIDEMIC | Physiological aspects | Metabolic diseases | Models | Animal models in research | Fructose | Methods
Journal Article
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