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British Journal of Cancer, ISSN 0007-0920, 2017, Volume 117, Issue 12, pp. 1777 - 1786
Background: Although chemotherapy is the cornerstone treatment for patients with metastatic colorectal cancer (mCRC), acquired chemoresistance is common and... 
Nuclear internalisation | Acquired resistance | IGF-1R | Colorectal cancer | BRAF mutation | colorectal cancer | I RECEPTOR | TUMOR-CELLS | COMBINATION | acquired resistance | INSULIN | nuclear internalisation | MUTATION STATUS | ONCOLOGY | POOR-PROGNOSIS | KRAS | INHIBITOR | TRANSCRIPTION FACTOR | EXPRESSION | Leucovorin - administration & dosage | Receptor, IGF Type 1 - metabolism | Molecular Chaperones - metabolism | Proto-Oncogene Proteins p21(ras) - genetics | Colorectal Neoplasms - genetics | Humans | Middle Aged | Panitumumab | Drug Resistance, Neoplasm | Male | Protein Inhibitors of Activated STAT - metabolism | Protein Transport - drug effects | Cell Nucleus - metabolism | Colorectal Neoplasms - drug therapy | Protein Inhibitors of Activated STAT - genetics | Camptothecin - administration & dosage | Camptothecin - analogs & derivatives | Cell Survival - drug effects | Bevacizumab - administration & dosage | Antibodies, Monoclonal - pharmacology | HCT116 Cells | Curcumin - pharmacology | Molecular Chaperones - genetics | Pyrimidines - pharmacology | Dasatinib - pharmacology | Signal Transduction - drug effects | Sorafenib | Fluorouracil - pharmacology | Niacinamide - analogs & derivatives | Antineoplastic Combined Chemotherapy Protocols - administration & dosage | Molecular Targeted Therapy | Organoplatinum Compounds - pharmacology | Organoplatinum Compounds - administration & dosage | Fluorouracil - administration & dosage | Oxaliplatin | Female | Antineoplastic Agents - pharmacology | Gene Silencing | Fatty Acids, Unsaturated - pharmacology | HT29 Cells | Pyrroles - pharmacology | Antibodies, Monoclonal - administration & dosage | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Proto-Oncogene Proteins B-raf - genetics | Cetuximab - administration & dosage | Aged | Phenylurea Compounds - pharmacology | Niacinamide - pharmacology | Colorectal Neoplasms - pathology | Immunohistochemistry | Medical research | Cell survival | Insulin-like growth factor I | RNA-mediated interference | Colorectal carcinoma | Chemoresistance | Clinical trials | Insulin-like growth factors | Metastasis | Insulin | Patients | Survival | Metastases | Proteins | SUMO protein | Chemotherapy | Cell lines | Monoclonal antibodies | Tumors | Cancer | Translational Therapeutics
Journal Article
Nature Communications, ISSN 2041-1723, 12/2017, Volume 8, Issue 1, pp. 410 - 14
Journal Article
Energy Economics, ISSN 0140-9883, 05/2017, Volume 64, p. 251
Concerns about the unequal distribution of greenhouse gas emissions attributable to mobility are gaining increasing attention in scholarly analyses as well as... 
Greenhouse effect | Accounting | Carbon dioxide | Socio-economic aspects | Mobility | Economic factors | Metropolitan areas | Energy policy | Social factors | Regression analysis | Public policy | Greenhouse gases | Socioeconomics | Emissions | Studies | Climate change | Travel | Socioeconomic factors | Emissions control | Cities | Emitters
Journal Article
Energy Economics, ISSN 0140-9883, 05/2017, Volume 64, pp. 251 - 261
Journal Article
Transport Policy, ISSN 0967-070X, 11/2017, Volume 60, pp. 54 - 62
EU Regulation 1370/2007 promotes competitive tendering as the main mechanism for awarding the provision of urban bus services. However, small concessions can... 
Local governments | Costs | Competitive tendering | Direct awarding | Urban bus system | Contractual practices | INDUSTRY | TRANSPORTATION | PERFORMANCE | FRONTIER MODELS | COST EFFICIENCY | PRIVATIZATION | DEREGULATION | LOCAL PUBLIC TRANSPORT | ECONOMICS | TECHNICAL EFFICIENCY | OWNERSHIP | BRITAIN | Local government
Journal Article
Nature Communications, ISSN 2041-1723, 05/2016, Volume 7, Issue 1, p. 11581
Cyclin D1 (Ccnd1) together with its binding partner Cdk4 act as a transcriptional regulator to control cell proliferation and migration, and abnormal... 
Journal Article
Research in Transportation Economics, ISSN 0739-8859, 09/2019, p. 100747
Journal Article
Energy Economics, ISSN 0140-9883, 05/2017, Volume 64, pp. 251 - 261
Concerns about the unequal distribution of greenhouse gas emissions attributable to mobility are gaining increasing attention in scholarly analyses as well as... 
Carbon dioxide emissions | Quantile regression | Climate change mitigation policies | HOUSEHOLD | DISTANCE | TRAVEL | CARBON | TRANSPORTATION | BEHAVIOR | DECOMPOSITION | CITY | ECONOMICS | QUANTILE REGRESSION APPROACH | Canvis climàtics | Carbon offsetting | Diòxid de carboni | Escalfament global | Carbon dioxide | Climatic changes | Global warming | Compensació d'emissions
Journal Article
The EMBO Journal, ISSN 0261-4189, 06/2018, Volume 37, Issue 12, p. n/a
Modification of chromosomal proteins by conjugation to SUMO is a key step to cope with DNA damage and to maintain the integrity of the genome. The recruitment... 
E3 ligase activity | repair | SUMO | Smc5/6 complex | DNA | Nse2 | ylation | SUMOylation | DNA repair | RECOMBINATION | UBIQUITIN-CONJUGATING ENZYME | BIOCHEMISTRY & MOLECULAR BIOLOGY | CORE COMPONENT | CELL BIOLOGY | MAINTENANCE | REPAIR | REPLICATION | INDUCED SUMOYLATION | BINDING | CONTRIBUTES | SUBUNIT | DNA, Fungal - genetics | Saccharomyces cerevisiae - genetics | Cell Cycle Proteins - metabolism | Ubiquitin-Protein Ligases - metabolism | Multiprotein Complexes - genetics | DNA, Fungal - chemistry | Saccharomyces cerevisiae Proteins - genetics | Ubiquitin-Protein Ligases - chemistry | Saccharomyces cerevisiae - chemistry | Cell Cycle Proteins - chemistry | Saccharomyces cerevisiae - metabolism | Multiprotein Complexes - metabolism | Multiprotein Complexes - chemistry | SUMO-1 Protein - chemistry | SUMO-1 Protein - genetics | DNA, Fungal - metabolism | Saccharomyces cerevisiae Proteins - metabolism | Cell Cycle Proteins - genetics | Sumoylation | SUMO-1 Protein - metabolism | DNA Damage | Enzyme Activation | Ubiquitin-Protein Ligases - genetics | Saccharomyces cerevisiae Proteins - chemistry | Binding | Chromatin | Yeast | Cell survival | DNA damage | Activation | Genomes | Electrostatic properties | Molecular chains | Proteins | SUMO protein | Conjugation | Sensors | Repair | Damage | Viability | Ubiquitin-protein ligase | Deoxyribonucleic acid--DNA | DNA Replication, Repair & Recombination | Post-translational Modifications, Proteolysis & Proteomics | Structural Biology | 6 complex | Smc5
Journal Article