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INORGANIC CHEMISTRY, ISSN 0020-1669, 03/2019, Volume 58, Issue 5, pp. 3382 - 3395
Amyloid-beta plaques, consisting of aggregated amyloid-beta peptides, are one of the pathological hallmarks of Alzheimer's disease. Copper complexes formed... 
OXIDATIVE STRESS | MECHANISM | SMALL-MOLECULE | BIS(THIOSEMICARBAZONATO) COMPLEXES | MOUSE MODEL | HYPOXIC SELECTIVITY | AGENTS | ELECTROCATALYTIC HYDROGEN EVOLUTION | METAL-COMPLEXES | ZINC | CHEMISTRY, INORGANIC & NUCLEAR | Index Medicus
Journal Article
Nuclear Medicine and Biology, ISSN 0969-8051, 07/2019, Volume 72-73, pp. S12 - S12
Journal Article
Nuclear Medicine and Biology, ISSN 0969-8051, 07/2019, Volume 72-73, p. S12
Journal Article
JOURNAL OF NUCLEAR MEDICINE, ISSN 0161-5505, 05/2019, Volume 60
Conference Proceeding
BIOCONJUGATE CHEMISTRY, ISSN 1043-1802, 02/2016, Volume 27, Issue 2, pp. 309 - 318
Two new bifunctional tris(hydroxypyridinone) (THP) chelators designed specifically for rapid labeling with Ga-68 have been synthesized, each with pendant... 
NEUROENDOCRINE TUMORS | BIOCHEMISTRY & MOLECULAR BIOLOGY | COMPLEXES | BIOCHEMICAL RESEARCH METHODS | RADIOMETALS | CHEMISTRY, ORGANIC | CHEMISTRY, MULTIDISCIPLINARY | ALPHA(V)BETA INTEGRIN EXPRESSION | RGD PEPTIDE | RADIOPHARMACEUTICALS | LIGANDS | RADIOSYNTHESIS | ANTAGONISTS | GALLIUM
Journal Article
BIOCONJUGATE CHEMISTRY, ISSN 1043-1802, 02/2017, Volume 28, Issue 2, pp. 481 - 495
Tris(hydroxypyridinone) chelators conjugated to peptides can rapidly complex the positron-emitting isotope gallium-68 (Ga-68) under mild conditions, and the... 
RHEUMATOID-ARTHRITIS | DIAGNOSIS | ANGIOGENESIS | RGD PEPTIDES | CHELATORS | BIOCHEMISTRY & MOLECULAR BIOLOGY | BIOCHEMICAL RESEARCH METHODS | CHEMISTRY, ORGANIC | MONOCLONAL-ANTIBODY | IRON | TUMORS | CHEMISTRY, MULTIDISCIPLINARY | PROSTATE-CANCER | AGENTS
Journal Article
Inorganic Chemistry, ISSN 0020-1669, 04/2019, Volume 58, Issue 7, pp. 4540 - 4552
The synthesis of new bis(thiosemicarbazonato)copper(II) complexes featuring poly-amine substituents via selective transamination reactions is presented.... 
HYPOXIA IMAGING AGENT | CU-64-ATSM IN-VITRO | OXIDATIVE STRESS | TUMOR HYPOXIA | MOUSE MODEL | SELECTIVE UPTAKE | MAGNETIC-RESONANCE | GROWTH-FACTOR | BLOOD-FLOW | PET | CHEMISTRY, INORGANIC & NUCLEAR | Index Medicus
Journal Article
DALTON TRANSACTIONS, ISSN 1477-9226, 2014, Volume 43, Issue 3, pp. 1386 - 1396
The use of copper radioisotopes in cancer diagnosis and radionuclide therapy is possible using chelators that are capable of binding Cu-II with sufficient... 
NEUROENDOCRINE TUMORS | SOMATOSTATIN ANALOG | BIFUNCTIONAL CHELATOR | BIOLOGICAL EVALUATION | BEARING RAT MODEL | RENAL UPTAKE | COPPER RADIOPHARMACEUTICALS | TARGETING PEPTIDES | IN-VIVO EVALUATION | BRIDGED MACROCYCLIC CHELATOR | CHEMISTRY, INORGANIC & NUCLEAR
Journal Article
JOURNAL OF MEDICAL IMAGING AND RADIATION ONCOLOGY, ISSN 1754-9477, 08/2013, Volume 57, Issue 4, pp. 475 - 481
Introduction For many cancers, tumour hypoxia is an adverse prognostic factor, and increases chemoradiation resistance; its importance in non-small cell lung... 
hypoxia | HEAD | FAZA | CARBOPLATIN | TUMOR HYPOXIA | OXYGENATION | TIRAPAZAMINE | NECK-CANCER | lung cancer | POSITRON-EMISSION-TOMOGRAPHY | F-18 FLUOROMISONIDAZOLE | F-18-FLUOROMISONIDAZOLE | RADIOTHERAPY | chemoradiation | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | PET
Journal Article
Tetrahedron Letters, ISSN 0040-4039, 09/2016, Volume 57, Issue 37, pp. 4119 - 4127
This digest highlights recent developments in the field of molecular imaging of cancer using peptide-based targeting entities. Syntheses of novel radiolabelled... 
Molecular imaging | Radiometals | Fluorine-18 | Carbon-11 | Peptides | Cancer | CHEMISTRY, ORGANIC | HETERODIMERIC PEPTIDE | CD13 RECEPTOR EXPRESSION | POSITRON-EMISSION-TOMOGRAPHY | BOMBESIN ANALOGS | PROSTATE-CANCER | BIFUNCTIONAL CHELATOR | BIOLOGICAL EVALUATION | BRADYKININ B1 RECEPTOR | IN-VIVO EVALUATION | PRECLINICAL EVALUATION | PET imaging | Fluorides | Implants, Artificial | Prosthesis
Journal Article
EJNMMI RESEARCH, ISSN 2191-219X, 10/2015, Volume 5
Background: Ge/Ga-68 generators provide an inexpensive source of a PET isotope to hospitals without cyclotron facilities. The development of new Ga-68-based... 
Molecular imaging | Octreotate | Hydroxypyridinone | NEUROENDOCRINE TUMORS | GA-68 RADIOPHARMACEUTICALS | Bifunctional chelator | THERAPEUTIC APPLICATIONS | PEPTIDES | Gallium-68 | LIGANDS | EXPRESSING TUMORS | RADIONUCLIDE THERAPY | CHELATOR | Somatostatin | RECEPTORS | Peptide receptor | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | GALLIUM
Journal Article
DALTON TRANSACTIONS, ISSN 1477-9226, 2015, Volume 44, Issue 11, pp. 4901 - 4909
New macrobicyclic cage amine or "sarcophagine" (sar) bifunctional chelators have been synthesised that form copper complexes of exceptional in vivo stability... 
BREAST-CANCER | ANTIBODY THERAPEUTICS | METAL COMPLEXATION | CONSTANTS | STABILITY | CITRATE | CHELATOR | LIGAND | SOLID-STATE | PET | CHEMISTRY, INORGANIC & NUCLEAR
Journal Article
Journal of Labelled Compounds and Radiopharmaceuticals, ISSN 0362-4803, 02/2018, Volume 61, Issue 2, pp. 61 - 67
Journal Article
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