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2005, ISBN 9780494078013
Metabotropic glutamate receptors (mGluRs) are emerging as promising drug targets for the treatment of several psychiatric and neurological disorders, including... 
Health Sciences, Pharmacology
eBook
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 11/2009, Volume 106, Issue 45, pp. 19197 - 19202
Journal Article
Nature Geoscience, ISSN 1752-0894, 06/2018, Volume 11, Issue 6, pp. 415 - 420
Journal Article
Journal Article
Molecular Pharmacology, ISSN 0026-895X, 02/2011, Volume 79, Issue 2, pp. 251 - 261
The M₃ muscarinic acetylcholine receptor (M3R) regulates many fundamental physiological functions. To identify novel M3R-interacting proteins, we used a... 
Humans | Receptor, Muscarinic M3 - metabolism | Cercopithecus aethiops | Endoplasmic Reticulum - metabolism | Rats | DNA Primers | Reverse Transcriptase Polymerase Chain Reaction | Microscopy, Confocal | Animals | Plasmids | Base Sequence | Cell Line, Tumor | Membrane Proteins - metabolism | Radioligand Assay | COS Cells | Index Medicus
Journal Article
Molecular Pharmacology, ISSN 0026-895X, 2/2011, Volume 79, Issue 2, pp. 251 - 261
The M 3 muscarinic acetylcholine receptor (M3R) regulates many fundamental physiological functions. To identify novel M3R-interacting proteins, we used a... 
Journal Article
Proceedings of the National Academy of Sciences of the United States, ISSN 0027-8424, 04/2010, Volume 107, Issue 17, p. 7999
Journal Article
Neuron, ISSN 0896-6273, 1999, Volume 23, Issue 1, pp. 181 - 192
Journal Article
Bioorganic and Medicinal Chemistry, ISSN 0968-0896, 12/2009, Volume 17, Issue 23, pp. 7987 - 7992
The important and diverse biological functions of adrenergic receptors, a subclass of G protein-coupled receptors (GPCRs), have made the search for compounds... 
G protein-coupledreceptors | Receptor modeling | Fluorine substitution | Adrenergic agonists | Catecholamines | Receptor selectivities | Point mutations
Journal Article
Proceedings of the National Academy of Sciences of the United States, ISSN 0027-8424, 11/2009, Volume 106, Issue 45, p. 19197
Impaired functioning of pancreatic [beta] cells is a key hallmark of type 2 diabetes. [beta] cell function is modulated by the actions of different classes of... 
Type 2 diabetes | Pancreatic beta cells | Development and progression | Biochemical genetics | Genetic aspects | Research | G proteins | Properties | Proteins | Rodents | Genetics | Diabetes | Pancreas | Gene expression | Insulin | Cells
Journal Article
Proceedings of the National Academy of Sciences, USA, ISSN 0027-8424, 04/2010, Volume 107, Issue 17, pp. 7999 - 8004
Therapeutic strategies that augment insulin release from pancreatic b-cells are considered beneficial in the treatment of type 2 diabetes. We previously... 
Journal Article
Bioorganic & Medicinal Chemistry, ISSN 0968-0896, 2009, Volume 17, Issue 23, pp. 7987 - 7992
The binding modes of 2FNE and 6FNE at the N293F mutant β -adrenergic receptor. The important and diverse biological functions of adrenergic receptors, a... 
G protein-coupledreceptors | Receptor modeling | Fluorine substitution | Adrenergic agonists | Catecholamines | Receptor selectivities | Point mutations
Journal Article
Proceedings of the National Academy of Sciences, USA, ISSN 0027-8424, 01/2009, Volume 106, Issue 45, pp. 19197 - 19202
Impaired functioning of pancreatic b cells is a key hallmark of type 2 diabetes. b cell function is modulated by the actionsof different classes of... 
Beta cells | Obesity | Signal transduction | Cell activation | G protein-coupled receptors | Diabetes mellitus | Transgenic mice | Glucose | Islets of Langerhans | Guanine nucleotide-binding protein | Pancreas | Insulin
Journal Article
CHANCE, ISSN 0933-2480, 04/2015, Volume 28, Issue 2, pp. 19 - 22
The increasing ability to acquire, store, and analyze large volumes of heterogeneous biomedical data has the potential to revolutionize society's understanding... 
Information science | Knowledge management | Biomedical research | Statistics
Journal Article
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