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Journal of the National Cancer Institute, ISSN 0027-8874, 12/2014, Volume 106, Issue 12, pp. dju349 - dju349
Journal Article
European journal of human genetics : EJHG, ISSN 1018-4813, 06/2019, Volume 27, Issue 11, pp. 1716 - 1723
Genome-wide association studies have led in the past to the discovery of susceptibility genes for many diseases including cancer and inflammatory conditions.... 
Genotyping | Decision making | Genes | Genomes | Transplantation | Inflammation | Chromosomes
Journal Article
Journal of Leukocyte Biology, ISSN 0741-5400, 11/2015, Volume 98, Issue 5, pp. 837 - 850
Journal Article
Human Heredity, ISSN 0001-5652, 06/2018, Volume 83, Issue 1, p. 21
Purpose: Radon exposure is a risk factor for lung cancer, strongest in underground uranium miners. A genome-wide interaction analysis was carried out to... 
Phenotypes | Radon | Lung cancer | Genes | Dealkylation | DNA damage | MiRNA | Genomes | Occupational exposure | DNA repair | Genotype & phenotype | Ubiquitination | Uranium | Genetics
Journal Article
by Wang, Yufei and McKay, James D and Rafnar, Thorunn and Wang, Zhaoming and Timofeeva, Maria N and Broderick, Peter and Zong, Xuchen and Laplana, Marina and Wei, Yongyue and Han, Younghun and Lloyd, Amy and Delahaye-Sourdeix, Manon and Chubb, Daniel and Gaborieau, Valerie and Wheeler, William and Chatterjee, Nilanjan and Thorleifsson, Gudmar and Sulem, Patrick and Liu, Geoffrey and Kaaks, Rudolf and Henrion, Marc and Kinnersley, Ben and Vallée, Maxime and Lecalvez-Kelm, Florence and Stevens, Victoria L and Gapstur, Susan M and Chen, Wei V and Zaridze, David and Szeszenia-Dabrowska, Neonilia and Lissowska, Jolanta and Rudnai, Peter and Fabianova, Eleonora and Mates, Dana and Bencko, Vladimir and Foretova, Lenka and Janout, Vladimir and Krokan, Hans E and Gabrielsen, Maiken Elvestad and Skorpen, Frank and Vatten, Lars and Njølstad, Inger and Chen, Chu and Goodman, Gary and Benhamou, Simone and Vooder, Tonu and Välk, Kristjan and Nelis, Mari and Metspalu, Andres and Lener, Marcin and Lubiński, Jan and Johansson, Mattias and Vineis, Paolo and Agudo, Antonio and Clavel-Chapelon, Francoise and Bueno-De-Mesquita, H. Bas and Trichopoulos, Dimitrios and Khaw, Kay-Tee and Johansson, Mikael and Weiderpass, Elisabete and Tjønneland, Anne and Riboli, Elio and Lathrop, Mark and Scelo, Ghislaine and Albanes, Demetrius and Caporaso, Neil E and Ye, Yuanqing and Gu, Jian and Wu, Xifeng and Spitz, Margaret R and Dienemann, Hendrik and Rosenberger, Albert and Su, Li and Matakidou, Athena and Eisen, Timothy and Stefansson, Kari and Risch, Angela and Chanock, Stephen J and Christiani, David C and Hung, Rayjean J and Brennan, Paul and Landi, Maria Teresa and Houlston, Richard S and Amos, Christopher I and Medicinska fakulteten and Institutionen för strålningsvetenskaper and Onkologi and Umeå universitet
Nature Genetics, ISSN 1061-4036, 2014, Volume 46, Issue 7, pp. 736 - 741
Journal Article
by McKay, J.D and Hung, R.J and Han, Y and Zong, X and Carreras-Torres, R and Christiani, D.C and Caporaso, N and Johansson, M and Li, Y and Byun, J.Y and Dunning, A and Pooley, K.A and Qian, D.C and Liu, G and Bojesen, S.E and Wu, X and Marchand, L. le and Albanes, D and Bickeböller, H and Alich, M.C and Bush, W.S and Tardon, A and Rennert, G and Teare, M.D and Field, J.K and Kiemeney, L.A and Lazarus, P and Haugen, A and Schabath, M.B and Anew, A.S and Shen, H and Hong, Y.C and Yuan, J.M and Bertazzi, P.A and Pesatori, A.C and Ye, Y and Diao, N and Su, L and Zhang, R and Brhane, Y and Leighl, N and Johansen, J.S and Mellemgaard, A and Saliba, W and Haiman, C.A and Wilkens, L.R and Fernandez-Somoano, A and Fernandez-Tardon, G and Heijden, H.F.M. van der and Kim, J.H and Hu, Z and Davies, M and Brunnström, H and Manjer, J and Melander, O and Muller, D and Overvad, K and Trichopoulou, A and Tumino, R and Doherty, J.A and Barnett, M.P and Chen, C and Goodman, G.E and Cox, A and Taylor, F and Woll, P.J and Brüske, I and Wichmann, H.E and Manz, J and Muley, T.R and Risch, A and Rosenberger, A and Grankvist, K and Shepherd, F.A and Tsao, M.S and Haura, E.B and Bolca, C and Holcatova, I and Janout, V and Kontic, M and Lissowska, J and Mukeria, A and Ognjanovic, S and Orlowski, T.M and Scelo, G and Swiatkowska, B and Zaridze, D and Bakke, P and Skaug, V and Zienolddiny, S and Duell, E.J and Butler, L.M and Koh, W.P and Gao, Y.T and Houlston, R.S and McLaughlin, J and Stevens, V.L and Joubert, P and Lamontagne, M and Nickle, D.C and ... and SpiroMeta Consortium and Medicinska fakulteten and Institutionen för medicinsk biovetenskap and Institutionen för strålningsvetenskaper and Umeå universitet
Nature Genetics, ISSN 1061-4036, 2017, Volume 49, Issue 7, pp. 1126 - 1132
Journal Article
by Ghinda, Diana and Chen, Suzan and Bedaiwy, Mahmoud and Jabri, Hussam and Alshardan, Mohammad and Taccone, Michael S and Lai, Carolyn and Rabski, Jessica and Tsai, Eve and Dedek, Annemarie and Xu, Jian and Tsai, Eve and Lombroso, Paul and Hildebrand, Mike and Mothe, Andrea and Tator, Charles H and Siladi, Andrew and Nally, Jaqueline and Stirling, David and Keller, Anastasia and Buckley, Christian and Shum-Siu, Alice and Magnuson, David and Rosenbaum, Benjamin P and Kelly, Michael L and Ahuja, Christopher and Ahuja, Christopher and Nori, Satoshi and Khazaei, Mohamad and Ahlfors, Jan-Eric and Liu, Yang and Wang, Jian and Fuehrmann, Tobias and Pakulska, Malgosia and Hettiaratchi, Marian H and Poon, Peter and Shoichet, Molly S and Fehlings, Michael G and Fehlings, Michael G and Fehlings, Michael G and Hazrati, Lili-Naz and Cherian, Leela and Nilewski, Lizanne and Tour, James M and Kent, Thomas A and Robertson, Claudia S and Wilde, Elisabeth and Newsome, Mary and Scheibel, Randall and Troyanskaya, Maya and Velez, Carmen and Wade, Benjamin and Drennon, Ann Marie and York, Gerald and Bigler, Erin and Abildskov, Tracy and Taylor, Brian and Jaramillo, Carlos and Eapen, Blessen and Belanger, Heather and Morey, Rajendra and Haswell, Courtney and Levin, Harvey and Hinds, Sidney and Walker, William and Walker, William and Kochunov, Peter and Jahanshad, Neda and Thompson, Paul and Tate, David and Statz, Jonathan and Goodrich, Jessica and Goforth, Cdr Carl and Tschiffely, Anna E and Arena, John D and Smith, Douglas H and Wolf, John A and Johnson, Victoria E and Rhodes, James and Friess, Stuart and Lee, Taylor and Lycke, Roy J and Jang, Ikbeom and Vike, Nicole L and Nauman, Eric A and Talavage, Thomas M and Rispoli, Joseph V and Alonso-Escalante, Jose and Fulton, William and Sodhi, Chhinder and Hackam, David J and Nasr, Isam W and Hubbard, W B and Joseph, Binoy and Spry, Malinda L and Vekaria, Hemendra J and Saatman, Kathryn and Sullivan, Patrick G and Sullivan, Patrick G and Vascak, Michal and ...
Journal of Neurotrauma, ISSN 0897-7151, 08/2018, Volume 35, Issue 16, pp. A-1 - A-285
[...]the vast majority of basic science pain research ends at target identification and validation in rodent models of chronic pain without confirmation in... 
Abstracts | Neurosciences | Keywords | Traumatic brain injury | Cytokines | Central nervous system | Inflammation | Gene expression | Trauma | Studies | Brain research | Hospitals | Pain | Rodents | Stem cells | DNA methylation | Biomarkers | Spinal cord injuries | Growth factors | Research centers | Proteins
Journal Article
Journal of Continuing Education in Nursing, ISSN 0022-0124, 2017, Volume 48, Issue 5, pp. 209 - 216
Background: It is unknown if completing educational modules on understanding, reviewing, and synthesizing research literature is associated with higher value... 
NURSES | BELIEFS | NURSING | KNOWLEDGE | Nursing Staff - psychology | Programmed Instruction as Topic | Education, Nursing, Continuing - methods | Nursing Staff - education | Humans | Middle Aged | Adult | Female | Male | Surveys and Questionnaires | Evidence-Based Practice - education | Health Knowledge, Attitudes, Practice
Journal Article
Journal of the National Cancer Institute, ISSN 0027-8874, 2010, Volume 102, Issue 13, pp. 959 - 971
BACKGROUND: Genome-wide association studies have identified three chromosomal regions at 15q25, 5p15, and 6p21 as being associated with the risk of lung... 
NICOTINE DEPENDENCE | POLYMORPHISMS | ONCOLOGY | PROGNOSTIC MARKER | SEQUENCE VARIANTS | RISK | GENETIC-VARIANTS | SMOKING | DNA-REPAIR | GENOME-WIDE ASSOCIATION | TELOMERE LENGTH | Smoking - adverse effects | Japan - epidemiology | Lung Neoplasms - ethnology | Tobacco Use Disorder - ethnology | United States - epidemiology | Carcinoma, Small Cell - genetics | Carcinoma, Squamous Cell - genetics | Humans | Middle Aged | Asian Continental Ancestry Group - genetics | Male | Carcinoma, Large Cell - ethnology | Case-Control Studies | Carcinoma, Squamous Cell - ethnology | Canada - epidemiology | Carcinoma, Small Cell - ethnology | Lung Neoplasms - etiology | Aged, 80 and over | Adult | Female | Tobacco Use Disorder - genetics | Adenocarcinoma - genetics | Carcinoma, Large Cell - genetics | Adenocarcinoma - ethnology | Korea - epidemiology | Odds Ratio | Quality Control | Lung Neoplasms - genetics | European Continental Ancestry Group - genetics | Genetic Predisposition to Disease | Genome-Wide Association Study | Genetic Association Studies | Risk Assessment | Europe | Gene Frequency | Risk Factors | Linkage Disequilibrium - genetics | Genotype | Smoking - genetics | International Cooperation | Chromosomes, Human, Pair 6 | Chromosomes, Human, Pair 5 | Homozygote | Singapore - epidemiology | Chromosomes, Human, Pair 15 | Aged | Polymorphism, Single Nucleotide | Quantitative trait loci | Genetic aspects | Research | Genetic susceptibility | Lung cancer | Risk factors
Journal Article
PLoS ONE, ISSN 1932-6203, 12/2012, Volume 7, Issue 12, p. e52898
We searched for a drug capable of sensitization of sarcoma cells to doxorubicin (DOX). We report that the dual PI3K/mTOR inhibitor PI103 enhances the efficacy... 
BREAST-CANCER CELLS | SOFT-TISSUE SARCOMAS | PROTEIN-1 EXPRESSION | INTERGROUP RHABDOMYOSARCOMA | MTOR INHIBITION | MULTIDISCIPLINARY SCIENCES | PHASE-II | FLOW-CYTOMETRIC ANALYSIS | CYTOCHROME-C RELEASE | MULTIDRUG-RESISTANCE | TOPOISOMERASE-II INHIBITORS | Gene Expression - drug effects | TOR Serine-Threonine Kinases - metabolism | Apoptosis - drug effects | Humans | ATP-Binding Cassette, Sub-Family B, Member 1 - metabolism | Caspase 3 - metabolism | Drug Resistance, Neoplasm | Sarcoma - enzymology | Phosphatidylinositol 3-Kinases - metabolism | Indazoles - administration & dosage | Phosphatidylinositol 3-Kinases - antagonists & inhibitors | Antineoplastic Combined Chemotherapy Protocols - pharmacology | TOR Serine-Threonine Kinases - antagonists & inhibitors | Doxorubicin - administration & dosage | Pyridines - administration & dosage | Pyrimidines - administration & dosage | Cytochromes c - metabolism | Multidrug Resistance-Associated Proteins - drug effects | bcl-2-Associated X Protein - metabolism | Enzyme Activation - drug effects | Sarcoma - drug therapy | Drug Synergism | Xenograft Model Antitumor Assays | Animals | Tumor Burden - drug effects | ATP-Binding Cassette, Sub-Family B, Member 1 - genetics | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Mice, Nude | Cell Line, Tumor | ATP Binding Cassette Transporter, Sub-Family B | Mice | Sulfonamides - administration & dosage | Furans - administration & dosage | Sarcoma | Anthracyclines | Apoptosis | TOR protein | Drugs | Pediatrics | Bax protein | Leukemia | Glioblastoma | Neuroblastoma | Kinases | Caspase-3 | Cancer therapies | Doxorubicin | Accumulation | MDR1 protein | Signal transduction | Mitochondria | Cell growth | Immunology | Xenografts | Genetics | Inhibition | Medical research | Tumor cells | Caspase | Permeability | Tumor cell lines | Gene expression | 1-Phosphatidylinositol 3-kinase | Chemotherapy | Inhibitors | Anthracycline | Cell lines | Tumors
Journal Article