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Immunity, ISSN 1074-7613, 03/2013, Volume 38, Issue 3, pp. 555 - 569
Monocyte-derived macrophages are essential for recovery after spinal cord injury, but their homing mechanism is poorly understood. Here, we show that although... 
ECTO-5'-NUCLEOTIDASE CD73 | EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS | DENDRITIC CELLS | MICROGLIA | REGENERATION | MONOCYTES | CNS | CENTRAL-NERVOUS-SYSTEM | IMMUNOLOGY | DIVERGENT | EXPRESSION | 5'-Nucleotidase - antagonists & inhibitors | 5'-Nucleotidase - genetics | Leukocyte Common Antigens - metabolism | Meninges - immunology | Spinal Cord - metabolism | Choroid Plexus - metabolism | Choroid Plexus - immunology | Monocytes - metabolism | Green Fluorescent Proteins - genetics | Monocytes - immunology | Spinal Cord Injuries - genetics | Cell Movement - genetics | Meninges - metabolism | Cell Movement - immunology | Leukocyte Common Antigens - immunology | Flow Cytometry | 5'-Nucleotidase - immunology | Gene Expression - immunology | Antigens, Ly - metabolism | Vascular Cell Adhesion Molecule-1 - genetics | Receptors, Chemokine - genetics | Macrophages - immunology | Green Fluorescent Proteins - metabolism | Vascular Cell Adhesion Molecule-1 - immunology | Blood-Brain Barrier - immunology | Mice, Inbred C57BL | Enzyme Inhibitors - pharmacology | Integrin alpha4beta1 - genetics | Receptors, Chemokine - immunology | Reverse Transcriptase Polymerase Chain Reaction | Adenosine Diphosphate - pharmacology | Blood-Brain Barrier - metabolism | Mice, Knockout | Integrin alpha4beta1 - immunology | Monocytes - drug effects | Spinal Cord - immunology | Microscopy, Confocal | Macrophages - metabolism | Animals | Antigens, Ly - immunology | Macrophages - drug effects | Spinal Cord Injuries - immunology | Mice | Adenosine Diphosphate - analogs & derivatives | CX3C Chemokine Receptor 1 | Spinal Cord Injuries - cerebrospinal fluid | Macrophages | Enzymes | Spinal cord injuries | Statistical analysis | Cytokines | Rodents | Recruitment | Index Medicus
Journal Article
Nature Medicine, ISSN 1078-8956, 02/2016, Volume 22, Issue 2, pp. 135 - 137
Journal Article
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, ISSN 1552-5260, 07/2017, Volume 13, Issue 7, p. P594
Journal Article
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, ISSN 1552-5260, 07/2017, Volume 13, Issue 7, pp. P594 - P594
Journal Article
Journal Article
Journal Article
Nature Communications, ISSN 2041-1723, 12/2019, Volume 10, Issue 1, pp. 465 - 15
Alzheimer's disease (AD) is a heterogeneous disorder with multiple etiologies. Harnessing the immune system by blocking the programmed cell death receptor... 
LEUKOCYTE INFILTRATION | MICROGLIA | ALZHEIMERS-DISEASE | MULTIDISCIPLINARY SCIENCES | REGULATORY T-CELLS | SYNAPSE LOSS | CENTRAL-NERVOUS-SYSTEM | CHOROID-PLEXUS | GLATIRAMER ACETATE | EXACERBATES TAU PATHOLOGY | BRAIN | Tauopathies - genetics | Cognitive Dysfunction - metabolism | Humans | Mice, Inbred C57BL | Programmed Cell Death 1 Receptor - metabolism | Mice, Transgenic | Programmed Cell Death 1 Receptor - antagonists & inhibitors | Antibodies, Blocking - pharmacology | Mice, Inbred Strains | B7-H1 Antigen - immunology | Brain - metabolism | B7-H1 Antigen - metabolism | Macrophages - metabolism | Tauopathies - metabolism | Animals | B7-H1 Antigen - antagonists & inhibitors | Alzheimer Disease - metabolism | Cognitive Dysfunction - genetics | Mice, Inbred BALB C | Programmed Cell Death 1 Receptor - immunology | Alzheimer Disease - genetics | Brain - immunology | Macrophages - immunology | Disease Models, Animal | Brain | Animal models | Disease | PD-1 protein | Cognitive ability | Parenchyma | Macrophages | Homing | Etiology | Immunotherapy | Dementia disorders | Alzheimer's disease | Movement disorders | Immune system | Immune response | Neurodegenerative diseases | Immunomodulation | Ribonucleic acid--RNA | Harnesses | Monocytes | Immune checkpoint | Tau protein | Cell death | PD-L1 protein | Cell migration | Apoptosis | Index Medicus
Journal Article
Brain, ISSN 0006-8950, 11/2013, Volume 136, Issue 11, pp. 3427 - 3440
Journal Article
by Honeybul, Stephen and Ho, Kwok and Lind, Christopher RP and Gillett, Grant R and Dreier, Jens P and Demertzi, Athena and Soddu, Andrea and Gomez, Francisco and Heine, Lizette and di Perri, Carol and Amico, Enrico and Laureys, Steven and Suehiro, Eiichi and Fujiyama, Yuichi and Koizumi, Hiroyasu and Suzuki, Michiyasu and Soubeyrand, Marc and Badner, Anna and Vawda, Reaz and Chung, Young Sun and G Fehlings, Michael and Dimou, Stefan and Biggs, Michael T and Lagopoulos, Jim and Marion, Donald and Bell, Michael J and Clifton, Guy L and Coffey, Christopher S and Fourwinds, Sierra and Zygun, David and Valadka, Alex and Smith, Kenneth R and Frisby, Melisa L and Bucholz, Richard D and Wilde, Elisabeth A and Levin, Harvey S and Okonkwo, David O and Igarashi, Yutaka and Yokobori, Shoji and Fujiki, Yu and Yamaguchi, Masahiro and Hashizume, Akihiro and Onda, Hidetaka and Araki, Takashi and Ogawa, Satoo and Fuse, Akira and Yokota, Hiroyuki and Semple, Bridgette D and Gimlin, Kayleen and O'Brien, Terence and Noble‐Haeusslein, Linda and Bradke, Frank and Todani, Masaki and Fujita, Motoki and Koga, Yasutaka and Nakahara, Takashi and Kaneko, Tadashi and Kaneda, Kotaro and Kawamura, Yoshikatsu and Oda, Yasutaka and Tsuruta, Ryosuke and Ivakhnenko, Dmitriy and Pertsov, Vladimir and Yoneda, Hiroshi and Beattie, Michael and Lee, Sang Mi and Lin, Amity and Sacramento, Jeffrey and Salegio, Ernesto and Mannent, Leda and Castel, Marie‐Noelle and Canolle, Benoit and Manley, Geoffrey T and Bresnahan, Jacqueline C and Munivenkatappa, Ashok and Rajeswaran, Jamuna and Devi, Bhagavatula Indira and Bennet, Niranjana and Upadhyay, Neeraj and Nelson, Neta R and Margulies, Susan S and Prins, Mayumi L and Gennarelli, Thomas A and Hartings, Jed A and Stamatakis, Emmanuel A and Czosnyka, Marek and Hinson, Holly and Brown, Brittney and Baguley, Ian and Schreiber, Martin and Bolcha, Martin and Hejčl, Aleš and Procházka, Jan and Hušková, Eva and Sameš, Martin and Bondi, Corina O and Cheng, Jeffrey P and Tennant, Heather M and Lajud, Naima and Monaco, Christina M and ...
Journal of Neurotrauma, ISSN 0897-7151, 03/2014, Volume 31, Issue 5, pp. A-1 - A-73
Journal Article
06/2019
A pharmaceutical composition comprising an active agent that causes reduction of the level of systemic immunosuppression in an individual for use in treating a... 
METALLURGY | PEPTIDES | HYGIENE | PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES | ORGANIC CHEMISTRY | CHEMISTRY | MEDICAL OR VETERINARY SCIENCE | HUMAN NECESSITIES
Patent
05/2019
본 명세서는 전신 면역 억제 수준을 감소시키는 유효성분을 포함하는 약학 조성물을 개시하며, 개체에서 CNS의 질병, 장애, 병태 또는 상해를 치료하는데 사용된다. 약학 조성물은 적어도 하나의 치료 과정을 포함하는 용량 요법으로 투여되며, 각 요법 과정은 미처리의 간격 기간이 뒤따르는... 
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS | HYGIENE | METALLURGY | PEPTIDES | PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES | ORGANIC CHEMISTRY | CHEMISTRY | MEDICAL OR VETERINARY SCIENCE | HUMAN NECESSITIES
Patent
04/2019
A pharmaceutical composition comprising an active agent that causes reduction of the level of systemic immunosuppression in an individual for use in treating a... 
METALLURGY | PEPTIDES | HYGIENE | PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES | ORGANIC CHEMISTRY | CHEMISTRY | MEDICAL OR VETERINARY SCIENCE | HUMAN NECESSITIES
Patent
02/2019
A pharmaceutical composition comprising an active agent that causes reduction of the level of systemic immunosuppression in an individual for use in treating a... 
METALLURGY | PEPTIDES | HYGIENE | PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES | ORGANIC CHEMISTRY | CHEMISTRY | MEDICAL OR VETERINARY SCIENCE | HUMAN NECESSITIES
Patent
12/2018
é fornecida uma composição farmacêutica compreendendo um agente ativo que causa a redução do nível de imunossupressão sistêmica num indivíduo pela liberação de... 
METALLURGY | PEPTIDES | HYGIENE | PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES | ORGANIC CHEMISTRY | CHEMISTRY | MEDICAL OR VETERINARY SCIENCE | HUMAN NECESSITIES
Patent
12/2018
A pharmaceutical composition comprising an active agent that causes reduction of the level of systemic immunosuppression in an individual for use in treating a... 
METALLURGY | PEPTIDES | HYGIENE | PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES | ORGANIC CHEMISTRY | CHEMISTRY | MEDICAL OR VETERINARY SCIENCE | HUMAN NECESSITIES
Patent
11/2018
A pharmaceutical composition comprising an active agent that causes reduction of the level of systemic immunosuppression in an individual by release of a... 
METALLURGY | PEPTIDES | HYGIENE | PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES | ORGANIC CHEMISTRY | CHEMISTRY | MEDICAL OR VETERINARY SCIENCE | HUMAN NECESSITIES
Patent
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