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2001, ISBN 0198523386, xvii, 466
Many neurological conditions are caused by damage to neurons and glial cells. For most of these diseases there are at present no effective treatments to... 
Brain damage | Treatment | Neurological intensive care | Cell transplantation | neuroscience
Book
Journal of Neurology, Neurosurgery & Psychiatry, ISSN 0022-3050, 09/2016, Volume 87, Issue Suppl 1, p. A46
BackgroundHuntington’s disease (HD) is an autosomal dominant, neurodegenerative movement disorder, typically characterised by chorea. Dystonia is another... 
Journal Article
Journal of Neurology, Neurosurgery & Psychiatry, ISSN 0022-3050, 09/2016, Volume 87, Issue Suppl 1, pp. A46 - A47
Journal Article
Journal of Neurology, Neurosurgery & Psychiatry, ISSN 0022-3050, 09/2016, Volume 87, Issue Suppl 1, pp. A99 - A99
BackgroundAlthough Huntington’s disease (HD) affects multiple brain areas it has a disproportionate and early effect on the striatal medium spiny neurons... 
Journal Article
Neuroreport, ISSN 0959-4965, 02/2014, Volume 25, Issue 3, pp. 159 - 159
Prior to clinical application; safety and efficacy of potential human donor cells for transplantation in neurodegenerative disease must first be demonstrated... 
Journal Article
ISSN 2047-4830, 9/2018, Volume 6, Issue 1, pp. 2571 - 2577
This study outlines the synthesis of microscale oxygen producing spheres, which, when used in conjunction with catalase, can raise the dissolved oxygen content... 
Journal Article
Nature Methods, ISSN 1548-7091, 09/2012, Volume 9, Issue 9, pp. 858 - 858
Journal Article
Neuroreport, ISSN 0959-4965, 02/2014, Volume 25, Issue 3, pp. 145 - 145
Although it remains the current 'gold standard' cell replacement therapy, characterisation of the functional efficacy of human primary tissue is currently... 
Journal Article
Biomaterials Science, ISSN 2047-4830, 10/2018, Volume 6, Issue 10, pp. 2571 - 2577
Oxygen-glucose deprivation detrimentally affected mesenchymal stem cells, which could be reversed by the addition of oxygen producing spheres. This study... 
Chemistry
Journal Article
Nature Biotechnology, ISSN 1087-0156, 05/2017, Volume 35, Issue 5, pp. 426 - 428
Direct conversion of astrocytes to dopamine neurons in vivo offers fresh optimism for the development of improved Parkinson's disease therapies. 
NEURONS | EFFICACY | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | MOUSE | Brain | Humans | Cellular Reprogramming | Care and treatment | Parkinson's disease | Brain research | Gene therapy | Parkinsons disease | Stem cells
Journal Article
Methods in molecular biology (Clifton, N.J.), ISSN 1064-3745, 2018, Volume 1780, pp. 573 - 583
Here, we describe detailed dissection and enzymatic dissociation protocols for the ganglionic eminences from the developing human brain to generate viable... 
Human | Striatum | Ganglionic eminence | Medium spiny neurons | Huntington’s disease | Dissociation | Fetal tissue | Dissection
Journal Article
Movement Disorders, ISSN 0885-3185, 09/2019, Volume 34, Issue 9, pp. 1381 - 1391
Journal Article
Journal Article
Journal of Neurology, Neurosurgery and Psychiatry, ISSN 0022-3050, 09/2018, Volume 89, Issue Suppl 1, p. A38
Background Preclinical and post-mortem studies reveal cerebrovascular abnormalities in the HD brain. Arterial spin labelling (ASL) MRI can be used to... 
Pathology
Journal Article
European Respiratory Journal, ISSN 0903-1936, 08/2016, Volume 48, Issue 2, pp. 585 - 588
Huntington's disease is an autosomal inherited monogenetic condition in which the mutation is an expansion of the cytosine-adenine-guanine (CAG) repeat... 
RESPIRATORY SYSTEM
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