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Advances In Anatomic Pathology, ISSN 1072-4109, 01/2018, Volume 25, Issue 1, pp. 1 - 13
Polyps of the gastrointestinal tract are very common lesions and most frequently sporadic in nature. Some polyp subtypes are associated with rare hereditary... 
Cowden syndrome | Polymerase proofreadingassociated polyposis | Juvenile polyposis syndrome | MUTYHassociated polyposis | Familial adenomatous polyposis | NTHL1-associated polyposis | Serrated polyposis syndrome | Peutz-Jeghers syndrome | MUTYH-associated polyposis | serrated polyposis syndrome | GENOTYPE-PHENOTYPE CORRELATIONS | juvenile polyposis syndrome | PEUTZ-JEGHERS-SYNDROME | polymerase proofreading-associated polyposis | PATHOLOGY | SERRATED POLYPOSIS | HIGH CANCER-RISK | COWDEN-SYNDROME | COLORECTAL-CANCER | JUVENILE POLYPOSIS | familial adenomatous polyposis | HAMARTOMA TUMOR SYNDROME | Colorectal Neoplasms - surgery | Neoplastic Syndromes, Hereditary - pathology | Pathology, Surgical - methods | Peutz-Jeghers Syndrome - pathology | Intestinal Polyposis - pathology | Intestinal Polyposis - genetics | Humans | Adenomatous Polyposis Coli - surgery | Neoplastic Syndromes, Hereditary - diagnosis | Neoplastic Syndromes, Hereditary - surgery | Intestinal Polyposis - diagnosis | Peutz-Jeghers Syndrome - genetics | Adenomatous Polyposis Coli - pathology | Colorectal Neoplasms - diagnosis | Gastrointestinal Tract - pathology | Gastrointestinal Tract - surgery | Intestinal Polyposis - congenital | Peutz-Jeghers Syndrome - diagnosis | Neoplastic Syndromes, Hereditary - genetics | Colorectal Neoplasms - pathology | Intestinal Polyposis - surgery | Adenomatous Polyposis Coli - diagnosis
Journal Article
Journal Article
Gut, ISSN 0017-5749, 01/2017, Volume 66, Issue 1, pp. 97 - 106
Objective Sessile serrated adenomas (SSAs) are the precursors of at least 15% of colorectal carcinomas, but their biology is incompletely understood. We... 
COLONIC POLYPS | COLON CARCINOGENESIS | COLORECTAL CANCER GENES | COLONIC NEOPLASMS | ISLAND METHYLATOR PHENOTYPE | COLON-CANCER | COLONOSCOPY | HYPERPLASTIC POLYPS | EARLY NEOPLASTIC PROGRESSION | BRAF MUTATION | PATHWAY | COLORECTAL-CANCER | MICROSATELLITE INSTABILITY | POOR SURVIVAL | GASTROENTEROLOGY & HEPATOLOGY | Adenoma - genetics | Proto-Oncogene Proteins p21(ras) - genetics | Colorectal Neoplasms - genetics | Humans | Middle Aged | Male | Tumor Suppressor Protein p14ARF - analysis | Carcinoma - chemistry | Young Adult | Colonic Polyps - genetics | Cell Transformation, Neoplastic - genetics | Aged, 80 and over | Neoplastic Syndromes, Hereditary - genetics | Wnt Signaling Pathway | Brain Neoplasms - genetics | Tumor Burden | DNA Repair Enzymes - analysis | Phenotype | MutL Protein Homolog 1 - genetics | CpG Islands | Carcinoma - genetics | Mutation | Age Factors | beta Catenin - analysis | Colonic Polyps - pathology | DNA Repair Enzymes - genetics | Colorectal Neoplasms - chemistry | Tumor Suppressor Protein p53 - genetics | Tumor Suppressor Protein p53 - analysis | Tumor Suppressor Proteins - genetics | Adult | Female | Carcinoma - pathology | DNA Modification Methylases - analysis | Cross-Sectional Studies | Gene Silencing | Adenoma - chemistry | Colonic Polyps - chemistry | beta Catenin - genetics | MutL Protein Homolog 1 - analysis | DNA Modification Methylases - genetics | Proto-Oncogene Proteins B-raf - genetics | Sex Factors | Adenoma - pathology | Aged | Tumor Suppressor Protein p14ARF - genetics | Cell Transformation, Neoplastic - pathology | Colorectal Neoplasms - pathology | Tumor Suppressor Proteins - analysis | Dysplasia | Usage | Carcinoma | Diagnosis | Clinical pathology | Cancer | DNA methylation | Bias | Deoxyribonucleic acid--DNA | Tumors | Index Medicus | Abridged Index Medicus
Journal Article
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, ISSN 0893-3952, 04/2019, Volume 32, Issue 10, pp. 1390 - 1415
Our understanding of serrated colorectal polyps has increased dramatically over the past two decades and has led to a modern classification scheme for these... 
Immunohistochemistry | Dysplasia | MLH1 protein | Colorectal carcinoma | Classification | Colon | Polyps
Journal Article
Modern Pathology, ISSN 0893-3952, 12/2017, Volume 30, Issue 12, pp. 1728 - 1738
Sessile serrated adenomas are the precursor polyp of approximately 20% of colorectal carcinomas. Sessile serrated adenomas with dysplasia are rarely... 
HYPERPLASTIC POLYPS | CANCERS | PATHWAY | GRADE | PATHOLOGY | CAUGHT | CARCINOMA | Immunohistochemistry | Dysplasia | MLH1 protein | Mismatch repair | Colorectal carcinoma | Morphology | Classification | Diagnosis | Polyps | Protein status | Tumors | Original
Journal Article
PLoS ONE, ISSN 1932-6203, 06/2013, Volume 8, Issue 6, p. e65479
Mutations in PIK3CA are present in 10 to 15% of colorectal carcinomas. We aimed to examine how PIK3CA mutations relate to other molecular alterations in... 
ISLAND METHYLATOR PHENOTYPE | POPULATION | COLON-CANCER CELLS | GENE | POOR SURVIVAL | MULTIDISCIPLINARY SCIENCES | RECEPTOR INHIBITOR CETUXIMAB | GROWTH | BRAF V600E MUTATION | KRAS | PREVALENCE | ras Proteins - genetics | Proto-Oncogene Proteins p21(ras) | Prospective Studies | Follow-Up Studies | Exons | Colorectal Neoplasms - genetics | Humans | Middle Aged | Transcriptional Activation | DNA Repair Enzymes - genetics | Male | DNA Methylation | Tumor Suppressor Proteins - genetics | Aged, 80 and over | Adult | Female | Colorectal Neoplasms - mortality | Proto-Oncogene Proteins - genetics | Phosphatidylinositol 3-Kinases - genetics | DNA Modification Methylases - genetics | Class I Phosphatidylinositol 3-Kinases | Proto-Oncogene Proteins B-raf - genetics | CpG Islands | Aged | Mutation | Colorectal Neoplasms - pathology | Immunohistochemistry | Carcinoma | Gene mutations | Colorectal cancer | Disease susceptibility | Genetic aspects | Cancer | Colorectal carcinoma | Systematic review | Metastasis | Microsatellite instability | Kinases | Epidemiology | K-Ras protein | O6-methylguanine-DNA methyltransferase | Genotype & phenotype | Epidermal growth factor | Cell cycle | Population | Colon | Deoxyribonucleic acid--DNA | CpG islands | Medical research | Microsatellites | Stability | Methylguanine | Stability analysis | Patients | Survival | Studies | Pathology | Councils | Medical prognosis | DNA methyltransferase | Tumors | Deoxyribonucleic acid | DNA
Journal Article
Journal Article
Modern Pathology, ISSN 0893-3952, 06/2013, Volume 26, Issue 6, pp. 825 - 834
KRAS-mutated carcinomas comprise 35-40% of all colorectal carcinomas but little is known about their characteristics. The aim of this study was to examine the... 
KRAS mutation | colorectal cancer | survival analysis | MGMT | colorectal polyp | molecular pathology | BRAF mutation | WILD-TYPE | PROMOTER METHYLATION | MICROSATELLITE INSTABILITY | PATHOLOGY | ISLAND METHYLATOR PHENOTYPE | COLON-CANCER | RECTAL-CANCER | BRAF MUTATIONS | LOW CIMP-LOW | KIRSTEN-RAS | KI-RAS MUTATIONS | Immunohistochemistry | ras Proteins - genetics | Microsatellite Instability | Proto-Oncogene Proteins p21(ras) | Prognosis | Prospective Studies | Colonic Polyps - pathology | Colorectal Neoplasms - genetics | Humans | Middle Aged | DNA Repair Enzymes - genetics | Carcinoma - mortality | Colorectal Neoplasms - chemistry | Male | Colonic Polyps - mortality | DNA Methylation | Colonic Polyps - genetics | Time Factors | DNA Mutational Analysis | Tumor Suppressor Proteins - genetics | Adult | Female | Cell Differentiation | Carcinoma - pathology | DNA Modification Methylases - analysis | Colorectal Neoplasms - mortality | Genetic Predisposition to Disease | Biomarkers, Tumor - analysis | Risk Factors | Victoria | Kaplan-Meier Estimate | Proportional Hazards Models | Proto-Oncogene Proteins - genetics | Chi-Square Distribution | DNA Repair Enzymes - analysis | DNA Modification Methylases - genetics | Phenotype | Proto-Oncogene Proteins B-raf - genetics | Carcinoma - genetics | Aged | Biomarkers, Tumor - genetics | Mutation | Colorectal Neoplasms - pathology | Tumor Suppressor Proteins - analysis
Journal Article
Modern Pathology, ISSN 0893-3952, 12/2013, Volume 26, Issue 12, pp. 1642 - 1656
Journal Article