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Introduction: This thesis discusses the importance of the target effct size (ES) used in clinical trials of health interventions. It investigates the common... 
Trials, ISSN 1745-6215, 12/2018, Volume 19, Issue 1, pp. 542 - 542
BACKGROUNDA key step in the design of a randomised controlled trial is the estimation of the number of participants needed. The most common approach is to... 
Index Medicus | Guidance | Clinically important difference | Target difference | Sample size | Randomised trial | Effect size
Journal Article
Trials, ISSN 1745-6215, 11/2018, Volume 19, Issue 1, pp. 606 - 606
A key step in the design of a RCT is the estimation of the number of participants needed in the study. The most common approach is to specify a target... 
Medicine, Experimental | Medical research | Usage | Analysis | Statistical sampling | Index Medicus
Journal Article
Trials, 06/2017, Volume 18, Issue 1, p. 271
A key step in the design of a randomised controlled trial (RCT) is the estimation of the number of participants needed. By far the most common approach is to... 
Endpoint Determination - standards | Sample Size | Delphi Technique | Humans | Research Design - standards | Consensus | Randomized Controlled Trials as Topic - standards
Journal Article
Trials, ISSN 1745-6215, 06/2017, Volume 18, Issue 1, pp. 271 - 271
The DELTA.sup.2 project has five components: systematic literature reviews of recent methodological developments (stage 1) and existing funder guidance (stage... 
Guidance | Pilot study | Target difference | Sample size | Effect size | Randomised controlled trial | Clinically important difference | Clinical trials | Models | Experimental design | Methods | Standards | Statistical sampling | Index Medicus
Journal Article
by Abbosh, Christopher and Birkbak, Nicolai J and Wilson, Gareth A and Jamal-Hanjani, Mariam and Constantin, Tudor and Salari, Raheleh and Le Quesne, John and Moore, David A and Veeriah, Selvaraju and Rosenthal, Rachel and Marafioti, Teresa and Kirkizlar, Eser and Watkins, Thomas B. K and McGranahan, Nicholas and Ward, Sophia and Martinson, Luke and Riley, Joan and Fraioli, Francesco and Al Bakir, Maise and Grönroos, Eva and Zambrana, Francisco and Endozo, Raymondo and Bi, Wenya Linda and Fennessy, Fiona M and Sponer, Nicole and Johnson, Diana and Laycock, Joanne and Shafi, Seema and Czyzewska-Khan, Justyna and Rowan, Andrew and Chambers, Tim and Matthews, Nik and Turajlic, Samra and Hiley, Crispin and Lee, Siow Ming and Forster, Martin D and Ahmad, Tanya and Falzon, Mary and Borg, Elaine and Lawrence, David and Hayward, Martin and Kolvekar, Shyam and Panagiotopoulos, Nikolaos and Janes, Sam M and Thakrar, Ricky and Ahmed, Asia and Blackhall, Fiona and Summers, Yvonne and Hafez, Dina and Naik, Ashwini and Ganguly, Apratim and Kareht, Stephanie and Shah, Rajesh and Joseph, Leena and Quinn, Anne Marie and Crosbie, Phil A and Naidu, Babu and Middleton, Gary and Langman, Gerald and Trotter, Simon and Nicolson, Marianne and Remmen, Hardy and Kerr, Keith and Chetty, Mahendran and Gomersall, Lesley and Fennell, Dean A and Nakas, Apostolos and Rathinam, Sridhar and Anand, Girija and Khan, Sajid and Russell, Peter and Ezhil, Veni and Ismail, Babikir and Irvin-Sellers, Melanie and Prakash, Vineet and Lester, Jason F and Kornaszewska, Malgorzata and Attanoos, Richard and Adams, Haydn and Davies, Helen and Oukrif, Dahmane and Akarca, Ayse U and Hartley, John A and Lowe, Helen L and Lock, Sara and Iles, Natasha and Bell, Harriet and Ngai, Yenting and Elgar, Greg and Szallasi, Zoltan and Schwarz, Roland F and Herrero, Javier and Stewart, Aengus and Quezada, Sergio A and Peggs, Karl S and Van Loo, Peter and Dive, Caroline and Lin, C. Jimmy and Rabinowitz, Matthew and Aerts, Hugo J. W. L and ... and TRACERx Consortium and The PEACE Consortium and TRACERx consortium and PEACE consortium and The PEACE consortium and The TRACERx consortium
Nature, ISSN 0028-0836, 04/2017, Volume 545, Issue 7655, pp. 446 - 451
Journal Article
by Bancroft, Elizabeth K and Page, Elizabeth C and Castro, Elena and Lilja, Hans and Vickers, Andrew and Sjoberg, Daniel and Assel, Melissa and Foster, Christopher S and Mitchell, Gillian and Drew, Kate and Mæhle, Lovise and Axcrona, Karol and Evans, D. Gareth and Bulman, Barbara and Eccles, Diana and McBride, Donna and van Asperen, Christi and Vasen, Hans and Kiemeney, Lambertus A and Ringelberg, Janneke and Cybulski, Cezary and Wokolorczyk, Dominika and Selkirk, Christina and Hulick, Peter J and Bojesen, Anders and Skytte, Anne-Bine and Lam, Jimmy and Taylor, Louise and Oldenburg, Rogier and Cremers, Ruben and Verhaegh, Gerald and van Zelst-Stams, Wendy A and Oosterwijk, Jan C and Blanco, Ignacio and Salinas, Monica and Cook, Jackie and Rosario, Derek J and Buys, Saundra and Conner, Tom and Ausems, Margreet G and Ong, Kai-ren and Hoffman, Jonathan and Domchek, Susan and Powers, Jacquelyn and Teixeira, Manuel R and Maia, Sofia and Foulkes, William D and Taherian, Nassim and Ruijs, Marielle and den Enden, Apollonia T. Helderman-van and Izatt, Louise and Davidson, Rosemarie and Adank, Muriel A and Walker, Lisa and Schmutzler, Rita and Tucker, Kathy and Kirk, Judy and Hodgson, Shirley and Harris, Marion and Douglas, Fiona and Lindeman, Geoffrey J and Zgajnar, Janez and Tischkowitz, Marc and Clowes, Virginia E and Susman, Rachel and Ramón y Cajal, Teresa and Patcher, Nicholas and Gadea, Neus and Spigelman, Allan and van Os, Theo and Liljegren, Annelie and Side, Lucy and Brewer, Carole and Brady, Angela F and Donaldson, Alan and Stefansdottir, Vigdis and Friedman, Eitan and Chen-Shtoyerman, Rakefet and Amor, David J and Copakova, Lucia and Barwell, Julian and Giri, Veda N and Murthy, Vedang and Nicolai, Nicola and Teo, Soo-Hwang and Greenhalgh, Lynn and Strom, Sara and Henderson, Alex and McGrath, John and Gallagher, David and Aaronson, Neil and Ardern-Jones, Audrey and Bangma, Chris and Dearnaley, David and Costello, Philandra and Eyfjord, Jorunn and Rothwell, Jeanette and Falconer, Alison and Gronberg, Henrik and Hamdy, Freddie C and ... and IMPACT Collaborators and Clinical Chemistry, Malmö and Klinisk kemi, Malmö and EpiHealth: Epidemiology for Health and Lund University and Lunds universitet
European Urology, ISSN 0302-2838, 2014, Volume 66, Issue 3, pp. 489 - 499
Journal Article
Journal Article
by Arce Vargas, Frederick and Furness, Andrew J.S and Solomon, Isabelle and Joshi, Kroopa and Mekkaoui, Leila and Lesko, Marta H and Miranda Rota, Enrique and Dahan, Rony and Georgiou, Andrew and Sledzinska, Anna and Ben Aissa, Assma and Franz, Dafne and Werner Sunderland, Mariana and Wong, Yien Ning Sophia and Henry, Jake Y and O’Brien, Tim and Nicol, David and Challacombe, Ben and Beers, Stephen A and Spain, Lavinia and Wotherspoon, Andrew and Francis, Nicholas and Smith, Amy and Smith, Sean and Smith, Myles and Smith, Elaine and Strauss, Dirk and Hayes, Andrew and Soultati, Aspasia and Stares, Mark and Lynch, Joanna and Fotiadis, Nicos and Fernando, Archana and Hazell, Steve and Chandra, Ashish and Pickering, Lisa and Rudman, Sarah and Chowdhury, Simon and Swanton, Charles and Jamal-Hanjani, Mariam and Veeriah, Selvaraju and Shafi, Seema and Czyzewska-Khan, Justyna and Johnson, Benjamin and Johnson, Diana and Laycock, Joanne and Bosshard-Carter, Leticia and Goh, Gerald and Rosenthal, Rachel and Gorman, Pat and Murugaesu, Nirupa and Hynds, Robert E and Wilson, Gareth and Birkbak, Nicolai J and Watkins, Thomas B.K and McGranahan, Nicholas and Horswell, Stuart and Mitter, Richard and Escudero, Mickael and Stewart, Aengus and Van Loo, Peter and Rowan, Andrew and Xu, Hang and Turajlic, Samra and Hiley, Crispin and Abbosh, Christopher and Goldman, Jacki and Stone, Richard Kevin and Denner, Tamara and Matthews, Nik and Matthews, Sue and Elgar, Greg and Ward, Sophia and Biggs, Jennifer and Costa, Marta and Begum, Sharmin and Phillimore, Ben and Chambers, Tim and Nye, Emma and Graca, Sofia and Al Bakir, Maise and Hartley, John A and Lowe, Helen L and Herrero, Javier and Lawrence, David and Hayward, Martin and Panagiotopoulos, Nikolaos and Kolvekar, Shyam and Falzon, Mary and Borg, Elaine and Simeon, Celia and Hector, Gemma and Aranda, Marie and Novelli, Marco and Oukrif, Dahmane and Janes, Sam M and Thakrar, Ricky and Forster, Martin and Ahmad, Tanya and Lee, Siow Ming and ... and Melanoma TRACERx Consortium and Renal TRACERx Consortium and Lung TRACERx Consortium
Immunity, ISSN 1074-7613, 04/2017, Volume 46, Issue 4, pp. 577 - 586