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by Traylor, Matthew and Farrall, Martin and Holliday, Elizabeth G and Sudlow, Cathie and Hopewell, Jemma C and Cheng, Yu-Ching and Fornage, Myriam and Ikram, M Arfan and Malik, Rainer and Bevan, Steve and Thorsteinsdottir, Unnur and Nalls, Mike A and Longstreth, WT and Wiggins, Kerri L and Yadav, Sunaina and Parati, Eugenio A and DeStefano, Anita L and Worrall, Bradford B and Kittner, Steven J and Khan, Muhammad Saleem and Reiner, Alex P and Helgadottir, Anna and Achterberg, Sefanja and Fernandez-Cadenas, Israel and Abboud, Sherine and Schmidt, Reinhold and Walters, Matthew and Chen, Wei-Min and Ringelstein, E Bernd and O'Donnell, Martin and Ho, Weang Kee and Pera, Joanna and Lemmens, Robin and Norrving, Bo and Higgins, Peter and Benn, Marianne and Sale, Michele and Kuhlenbäumer, Gregor and Doney, Alexander S F and Vicente, Astrid M and Delavaran, Hossein and Algra, Ale and Davies, Gail and Oliveira, Sofia A and Palmer, Colin N A and Deary, Ian and Schmidt, Helena and Pandolfo, Massimo and Montaner, Joan and Carty, Cara and de Bakker, Paul I W and Kostulas, Konstantinos and Ferro, Jose M and van Zuydam, Natalie R and Valdimarsson, Einar and Nordestgaard, Børge G and Lindgren, Arne and Thijs, Vincent and Slowik, Agnieszka and Saleheen, Danish and Paré, Guillaume and Berger, Klaus and Thorleifsson, Gudmar and Hofman, Albert and Mosley, Thomas H and Mitchell, Braxton D and Furie, Karen and Clarke, Robert and Levi, Christopher and Seshadri, Sudha and Gschwendtner, Andreas and Boncoraglio, Giorgio B and Sharma, Pankaj and Bis, Joshua C and Gretarsdottir, Solveig and Psaty, Bruce M and Rothwell, Peter M and Rosand, Jonathan and Meschia, James F and Stefansson, Kari and Dichgans, Martin and Markus, Hugh S and The Australian Stroke Genetics Collaborative, Wellcome Trust Case Control Consortium 2 (WTCCC2) and on behalf of the International Stroke Genetics Consortium and WTCCC 2 and Australian Stroke Genetics Collabo and Int Stroke Genetics Consortium and International Stroke Genetics Consortium and Australian Stroke Genetics Collaborative, Wellcome Trust Case Control Consortium 2 (WTCCC2)
Lancet neurology, ISSN 1474-4422, 2012, Volume 11, Issue 11, pp. 951 - 962
Journal Article
by Helgadottir, Anna and Gretarsdottir, Solveig and Thorleifsson, Gudmar and Holm, Hilma and Patel, Riyaz S and Gudnason, Thorarinn and Jones, Gregory T and van Rij, Andre M and Eapen, Danny J and Baas, Annette F and Tregouet, David-Alexandre and Morange, Pierre-Emmanuel and Emmerich, Joseph and Lindblad, Bengt and Gottsäter, Anders and Kiemeny, Lambertus A and Lindholt, Jes S and Sakalihasan, Natzi and Ferrell, Robert E and Carey, David J and Elmore, James R and Tsao, Philip S and Grarup, Niels and Jørgensen, Torben and Witte, Daniel R and Hansen, Torben and Pedersen, Oluf and Pola, Roberto and Gaetani, Eleonora and Magnadottir, Hulda B and Wijmenga, Cisca and Tromp, Gerard and Ronkainen, Antti and Ruigrok, Ynte M and Blankensteijn, Jan D and Mueller, Thomas and Wells, Philip S and Corral, Javier and Soria, Jose Manuel and Souto, Juan Carlos and Peden, John F and Jalilzadeh, Shapour and Mayosi, Bongani M and Keavney, Bernard and Strawbridge, Rona J and Sabater-Lleal, Maria and Gertow, Karl and Baldassarre, Damiano and Nyyssönen, Kristiina and Rauramaa, Rainer and Smit, Andries J and Mannarino, Elmo and Giral, Philippe and Tremoli, Elena and de Faire, Ulf and Humphries, Steve E and Hamsten, Anders and Haraldsdottir, Vilhelmina and Olafsson, Isleifur and Magnusson, Magnus K and Samani, Nilesh J and Levey, Allan I and Markus, Hugh S and Kostulas, Konstantinos and Dichgans, Martin and Berger, Klaus and Kuhlenbäumer, Gregor and Ringelstein, E. Bernd and Stoll, Monika and Seedorf, Udo and Rothwell, Peter M and Powell, Janet T and Kuivaniemi, Helena and Onundarson, Pall T and Valdimarsson, Einar and Matthiasson, Stefan E and Gudbjartsson, Daniel F and Thorgeirsson, Guðmundur and Quyyumi, Arshed A and Watkins, Hugh and Farrall, Martin and Thorsteinsdottir, Unnur and Stefansson, Kari
Journal of the American College of Cardiology, ISSN 0735-1097, 2012, Volume 60, Issue 8, pp. 722 - 729
Objectives The purpose of this study is investigate the effects of variants in the apolipoprotein(a) gene ( LPA ) on vascular diseases with different... 
Cardiovascular | Internal Medicine | atherosclerosis | genetic | association | thrombosis | lipoprotein(a) | INTIMA-MEDIA THICKNESS | RISK-FACTORS | METAANALYSIS | MYOCARDIAL-INFARCTION | UMCG Approved | VASCULAR-DISEASE | WOMEN | PERIPHERAL ARTERIAL-DISEASE | ISCHEMIC-STROKE | SEVERITY | CARDIAC & CARDIOVASCULAR SYSTEMS | Severity of Illness Index | Myocardial Infarction - genetics | European Continental Ancestry Group - genetics | Genetic Predisposition to Disease | Apolipoproteins A - genetics | Angiography | Carotid Intima-Media Thickness | Intracranial Aneurysm - genetics | Atherosclerosis - genetics | Humans | Risk Factors | Brain Ischemia - genetics | African Americans - genetics | Linear Models | Logistic Models | Aortic Aneurysm, Abdominal - genetics | Stroke - genetics | Venous Thromboembolism - genetics | Peripheral Arterial Disease - genetics | Age of Onset | Coronary Artery Disease - genetics | Polymorphism, Single Nucleotide | Odds Ratio | Medical colleges | Neurosciences | Stock options | Genes | Aneurysms | Coronary heart disease | Biometry | Lipoprotein A | Anopheles | Atherosclerosis | Medical genetics | Genetic research | Genetic aspects | Diabetes | Thromboembolism | Cardiology | Public health | Dementia | Stroke | Medical imaging | Values | Cardiovascular disease | Apolipoproteins | Thrombosis | Studies | Confidence intervals | Coronary vessels | Blood pressure | Drug therapy | Age | Methods | Kardiologi | Clinical Medicine | Cardiac and Cardiovascular Systems | Medical and Health Sciences | Medicin och hälsovetenskap | Klinisk medicin
Journal Article
by Anttila, Verneri and Bulik-Sullivan, Brendan and Finucane, Hilary K and Walters, Raymond K and Bras, Jose and Duncan, Laramie and Escott-Price, Valentina and Falcone, Guido J and Gormley, Padhraig and Malik, Rainer and Patsopoulos, Nikolaos A and Ripke, Stephan and Wei, Zhi and Yu, Dongmei and Lee, Phil H and Grenier-Boley, Benjamin and Chouraki, Vincent and Kamatani, Yoichiro and Berr, Claudine and Letenneur, Luc and Hannequin, Didier and Amouyel, Philippe and Boland, Anne and Deleuze, Jean-François and Duron, Emmanuelle and Vardarajan, Badri N and Reitz, Christiane and Goate, Alison M and Huentelman, Matthew J and Rogaeva, Ekaterina and St George-Hyslop, Peter and Hakonarson, Hakon and Kukull, Walter A and Farrer, Lindsay A and Beach, Thomas G and Head, Elizabeth and Jicha, Gregory A and Kauwe, John S.K and Kaye, Jeffrey A and Levey, Allan I and Lieberman, Andrew P and Pankratz, Vernon S and Poon, Wayne W and Quinn, Joseph F and Saykin, Andrew J and Schneider, Lon S and Smith, Amanda G and Sonnen, Joshua A and Stern, Robert A and Van Eldik, Linda J and Russo, Giancarlo and Rubinsztein, David C and Tsolaki, Magda and Proitsi, Petra and Fox, Nick C and Hampel, Harald and Owen, Michael J and Mead, Simon and Morgan, Kevin and Schott, Jonathan M and Rossor, Martin and Lupton, Michelle K and Hoffmann, Per and Kornhuber, Johannes and McQuillin, Andrew and Al-Chalabi, Ammar and Bis, Joshua C and Ruiz, Agustin and Boada, Mercè and Seshadri, Sudha and Beiser, Alexa and Rice, Kenneth and De Jager, Philip L and Geschwind, Daniel H and Riemenschneider, Matthias and Riedel-Heller, Steffi and Rotter, Jerome I and Ransmayr, Gerhard and Hyman, Bradley T and Winsvold, Bendik and Palta, Priit and Farh, Kai-How and Cuenca-Leon, Ester and Furlotte, Nicholas and Ligthart, Lannie and Terwindt, Gisela M and Freilinger, Tobias and Ran, Caroline and Borck, Guntram and Lehtimäki, Terho and Wedenoja, Juho and Buring, Julie E and Schürks, Markus and Hottenga, Jouke-Jan and Penninx, Brenda and Artto, Ville and Martin, Nicholas G and Montgomery, Grant W and Kurki, Mitja I and Hämäläinen, Eija and ... and The Brainstorm Consortium and Brainstorm Consortium
Science (American Association for the Advancement of Science), ISSN 1095-9203, 2018, Volume 360, Issue 6395, pp. eaap8757 - 1313
Disorders of the brain can exhibit considerable epidemiological comorbidity and often share symptoms, provoking debate about their etiologic overlap. We... 
ANOREXIA-NERVOSA | MULTIPLE-SCLEROSIS | DEFICIT HYPERACTIVITY DISORDER | LONG-TERM SURVIVAL | ALZHEIMERS-DISEASE | MULTIDISCIPLINARY SCIENCES | GENETIC CORRELATIONS | SUSCEPTIBILITY LOCI | BODY-MASS INDEX | BIPOLAR DISORDER | GENOME-WIDE ASSOCIATION | Genetic Variation | Mental Disorders - genetics | Genome-Wide Association Study | Phenotype | Brain Diseases - classification | Quantitative Trait, Heritable | Brain Diseases - diagnosis | Humans | Mental Disorders - classification | Risk Factors | Brain Diseases - genetics | Mental Disorders - diagnosis | Headache | Anorexia | Mental disorders | Disorders | Cognitive ability | Schizophrenia | Risk sharing | Bipolar disorder | Genomes | Posttraumatic stress disorder | Mental depression | Epidemiology | Risk factors | Consortia | Proteins | Heterogeneity | Biological effects | Ischemia | Etiology | Risk assessment | Classification | Gilles de la Tourette syndrome | Alzheimer's disease | Neurological disorders | Stroke | Phenotypes | Neurodegenerative diseases | Comorbidity | Migraine | Attention deficit hyperactivity disorder | Eating disorders | Personality | Genetic diversity | Behavior disorders | Anorexia nervosa | Risk analysis | Patients | Statistics | Activity patterns | Neurological diseases | Crohn's Disease | Population (statistical) | Scaffolding | Correlation analysis | Heritability | Diagnostic systems | Alzheimers disease | Life Sciences | Human health and pathology | Mental Disorders | Neurons and Cognition | Brain Diseases | Genetics
Journal Article
by Williams, Frances M. K and Carter, Angela M and Hysi, Pirro G and Surdulescu, Gabriela and Hodgkiss, Dylan and Soranzo, Nicole and Traylor, Matthew and Bevan, Steve and Dichgans, Martin and Rothwell, Peter M. W and Sudlow, Cathie and Farrall, Martin and Silander, Kaisa and Kaunisto, Mari and Wagner, Peter and Saarela, Olli and Kuulasmaa, Kari and Virtamo, Jarmo and Salomaa, Veikko and Amouyel, Philippe and Arveiler, Dominique and Ferrieres, Jean and Wiklund, Per-Gunnar and Arfan Ikram, M and Hofman, Albert and Boncoraglio, Giorgio B and Parati, Eugenio A and Helgadottir, Anna and Gretarsdottir, Solveig and Thorsteinsdottir, Unnur and Thorleifsson, Gudmar and Stefansson, Kari and Seshadri, Sudha and DeStefano, Anita and Gschwendtner, Andreas and Psaty, Bruce and Longstreth, Will and Mitchell, Braxton D and Cheng, Yu-Ching and Clarke, Robert and Ferrario, Marco and Bis, Joshua C and Levi, Christopher and Attia, John and Holliday, Elizabeth G and Scott, Rodney J and Fornage, Myriam and Sharma, Pankaj and Furie, Karen L and Rosand, Jonathan and Nalls, Mike and Meschia, James and Mosely, Thomas H and Evans, Alun and Palotie, Aarno and Markus, Hugh S and Grant, Peter J and Spector, Tim D and on Behalf of the EuroCLOT Investigators the Wellcome Trust Case Control Consortium 2 MOnica Risk, Genetics, Archiving and Monograph MetaStroke and the International Stroke Genetics Consortium and EuroCLOT Investigators and Wellcome Trust Case Control Consor and Int Stroke Genetics Consortium and MOnica Risk, Genetics, Archiving and Monograph and MetaStroke and International Stroke Genetics Consortium and Wellcome Trust Case Control Consortium 2
Annals of neurology, ISSN 0364-5134, 2013, Volume 73, Issue 1, pp. 16 - 31
Journal Article
The Lancet (British edition), ISSN 0140-6736, 2011, Volume 377, Issue 9782, pp. 2013 - 2022
Journal Article
by Franceschini, Nora and Giambartolomei, Claudia and de Vries, Paul S and Finan, Chris and Bis, Joshua C and Huntley, Rachael P and Lovering, Ruth C and Tajuddin, Salman M and Winkler, Thomas W and Graff, Misa and Kavousi, Maryam and Dale, Caroline and Smith, Albert V and Hofer, Edith and van Leeuwen, Elisabeth M and Nolte, Ilja M and Lu, Lingyi and Scholz, Markus and Sargurupremraj, Muralidharan and Pitkänen, Niina and Franzén, Oscar and Joshi, Peter K and Noordam, Raymond and Marioni, Riccardo E and Hwang, Shih-Jen and Musani, Solomon K and Schminke, Ulf and Palmas, Walter and Isaacs, Aaron and Correa, Adolfo and Zonderman, Alan B and Hofman, Albert and Teumer, Alexander and Cox, Amanda J and Uitterlinden, André G and Wong, Andrew and Smit, Andries J and Newman, Anne B and Britton, Annie and Ruusalepp, Arno and Sennblad, Bengt and Hedblad, Bo and Pasaniuc, Bogdan and Penninx, Brenda W and Langefeld, Carl D and Wassel, Christina L and Tzourio, Christophe and Fava, Cristiano and Baldassarre, Damiano and O’Leary, Daniel H and Teupser, Daniel and Kuh, Diana and Tremoli, Elena and Mannarino, Elmo and Grossi, Enzo and Boerwinkle, Eric and Schadt, Eric E and Ingelsson, Erik and Veglia, Fabrizio and Rivadeneira, Fernando and Beutner, Frank and Chauhan, Ganesh and Heiss, Gerardo and Snieder, Harold and Campbell, Harry and Völzke, Henry and Markus, Hugh S and Deary, Ian J and Jukema, J. Wouter and de Graaf, Jacqueline and Price, Jacqueline and Pott, Janne and Hopewell, Jemma C and Liang, Jingjing and Thiery, Joachim and Engmann, Jorgen and Gertow, Karl and Rice, Kenneth and Taylor, Kent D and Dhana, Klodian and Kiemeney, Lambertus A. L. M and Lind, Lars and Raffield, Laura M and Launer, Lenore J and Holdt, Lesca M and Dörr, Marcus and Dichgans, Martin and Traylor, Matthew and Sitzer, Matthias and Kumari, Meena and Kivimaki, Mika and Nalls, Mike A and Melander, Olle and Raitakari, Olli and Franco, Oscar H and Rueda-Ochoa, Oscar L and Roussos, Panos and Whincup, Peter H and Amouyel, Philippe and Giral, Philippe and ... and MEGASTROKE Consortium and Institutionen för neurovetenskap och fysiologi, sektionen för klinisk neurovetenskap and Göteborgs universitet and Gothenburg University and Institute of Biomedicine, Department of Pathology and Core Facilities, Bioinformatics and Sahlgrenska Academy and Institutionen för biomedicin, avdelningen för patologi and Sahlgrenska akademin and Institute of Neuroscience and Physiology, Department of Clinical Neuroscience
Nature communications, ISSN 2041-1723, 2018, Volume 9, Issue 1, pp. 5141 - 14
Carotid artery intima media thickness (cIMT) and carotid plaque are measures of subclinical atherosclerosis associated with ischemic stroke and coronary heart... 
no | HEART | METAANALYSIS | VARIANTS | INTEGRATIVE ANALYSIS | MULTIDISCIPLINARY SCIENCES | CORONARY-ARTERY-DISEASE | GENE-PRODUCT | GENOME-WIDE ASSOCIATION | Genetic Predisposition to Disease - genetics | Plaque, Atherosclerotic - genetics | Carotid Intima-Media Thickness | Humans | Risk Factors | ADAMTS9 Protein - genetics | Lod Score | Amino Acid Oxidoreductases - genetics | Coronary Disease - pathology | Coronary Disease - genetics | Polymorphism, Single Nucleotide | Genome-Wide Association Study - methods | Plaque, Atherosclerotic - pathology | Quantitative Trait Loci - genetics | Heart | Stroke | Genes | Cardiovascular disease | Genomes | Regression analysis | Tissues | Loci | Coronary artery disease | Ischemia | Arteriosclerosis | Atherosclerosis | Regulatory mechanisms (biology) | Carotid artery | Cardiovascular diseases | Heart diseases | coronary artery disease | B scan | single nucleotide polymorphism | ischemic heart disease | heart atrium appendage | genetic regulation | STEAP2-AS1 gene | epigenetics | carotid atherosclerosis | protein | genetic risk | genetic correlation | genetic susceptibility | PIK3CG gene | cell component | cardiovascular system | brain ischemia | CFDP1-TMEM170A gene | gene | TMCO5B gene | ADAMTS9 protein | human cell | chromosome 8 | cerebrovascular accident | internal mammary artery | adipose derived stem cell | expression quantitative trait locus | genetic analysis | chromosome 7 | clinical outcome | apolipoprotein E | nonhuman | gene expression | unclassified drug | EDNRA gene | Article | cell | gene control | Medicinsk genetik | Medical Genetics | artery wall | regulatory mechanism | cell adhesion | genomics | tibial artery | loxl4 protein | human | cardiovascular disease | mesenchymal stem cell | stroke | disease association | arterial wall thickness | gene frequency | genetic epidemiology | genetic variability | gene locus | genome-wide association study
Journal Article
Nature (London), ISSN 1476-4687, 2019, Volume 567, Issue 7749, pp. 479 - 485
...], Javier Herrero [sup.2], Sergio A. Quezada [sup.1] [sup.8] [sup.9], Jonas Demeulemeester [sup.4] [sup.18], Peter Van Loo [sup.4] [sup.18], Stephan Beck [sup.10... 
TUMOR-INFILTRATING LYMPHOCYTES | THERAPY | CELL | MULTIDISCIPLINARY SCIENCES | Adenocarcinoma - pathology | Prognosis | Carcinoma, Squamous Cell - genetics | Carcinoma, Squamous Cell - pathology | Humans | Lung Neoplasms - pathology | Male | Female | Adenocarcinoma - genetics | Gene Expression Regulation, Neoplastic - genetics | Tumor Escape - immunology | Carcinoma, Non-Small-Cell Lung - pathology | Lung Neoplasms - genetics | Antigens, Neoplasm - genetics | Antigens, Neoplasm - immunology | Carcinoma, Non-Small-Cell Lung - genetics | Adenocarcinoma - immunology | Antigen Presentation - immunology | Carcinoma, Squamous Cell - immunology | Carcinoma, Non-Small-Cell Lung - immunology | Tumor Microenvironment - immunology | Disease-Free Survival | Lung Neoplasms - immunology | Evolution, Molecular | Lymphocytes, Tumor-Infiltrating - immunology | Causes of | Development and progression | Genetic aspects | Cellular immunity | Lung cancer | RNA sequencing | Epigenetic inheritance | Medical colleges | Histocompatibility antigens | RNA | Tumor antigens | HLA histocompatibility antigens | Lung cancer, Non-small cell | Tumors | Working groups | Brain cancer | Editing | Genomes | Metastases | Gene sequencing | Histopathology | Lymphocytes | Evolution | Bioinformatics | Immune system | Antigens | T cell receptors | Ribonucleic acid--RNA | Estimates | Heterozygosity | White blood cells | Pathology | Depletion | Loss of heterozygosity | Epigenetics | Biomarkers | Ligands | Infiltration | Microenvironments | Mutation | Cancer
Journal Article