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Cell, ISSN 0092-8674, 06/2015, Volume 161, Issue 6, pp. 1252 - 1265
Journal Article
ACS Medicinal Chemistry Letters, ISSN 1948-5875, 04/2014, Volume 5, Issue 4, pp. 434 - 439
Sterol 14α-demethylase (CYP51) is an important therapeutic target for fungal and parasitic infections due to its key role in the biosynthesis of ergosterol, an... 
inhibitors | R -configuration | T. cruzi | CYP51 | CHEMISTRY, MEDICINAL | POSACONAZOLE | SCOPE | CHAGAS-DISEASE | DRUG DESIGN | R-configuration | DISCOVERY | ARYL BROMIDES | CATALYZED AMINATION | CHEMISTRY | AGENTS | WATER
Journal Article
Nature Reviews Drug Discovery, ISSN 1474-1776, 2018, Volume 17, Issue 8, pp. 588 - 606
Danger signals are a hallmark of many common inflammatory diseases, and these stimuli can function to activate the cytosolic innate immune signalling receptor... 
GASDERMIN D | IL-1-BETA SECRETION | DENDRITIC CELLS | BAY 11-7082 | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | AMYLOID-BETA | ACTIVATION DOWNSTREAM | PHARMACOLOGY & PHARMACY | MURINE MODELS | NF-KAPPA-B | HUMAN MONOCYTES | NALP3 INFLAMMASOME | NLRP3 | Care and treatment | Inflammation | Models | Research | Inflammatory diseases
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 04/2011, Volume 364, Issue 17, pp. 1607 - 1616
Journal Article
Organic Letters, ISSN 1523-7060, 12/2009, Volume 11, Issue 23, pp. 5538 - 5541
Density functional theory was used to locate transition states for hydroboration reactions of allenes with 9-borabicyclo[3.3.1]nonane and... 
CHEMISTRY, ORGANIC | ASYMMETRIC ALLYLBORATION | ALDEHYDES | STEREOSELECTIVE-SYNTHESIS | GEOMETRIC ISOMERS | Boron Compounds - chemistry | Thermodynamics | Molecular Structure | Kinetics | Alkadienes - chemistry | Alkanes - chemistry
Journal Article
Cancer Research, ISSN 0008-5472, 02/2014, Volume 74, Issue 3, pp. 908 - 920
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 11/2014, Volume 57, Issue 22, pp. 9598 - 9611
Journal Article
Current topics in medicinal chemistry, ISSN 1568-0266, 2017, Volume 17, Issue 1, pp. 30 - 39
Journal Article