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Movement Disorders, ISSN 0885-3185, 06/2016, Volume 31, Issue 6, pp. 889 - 897
Journal Article
Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, ISSN 2167-8421, 07/2019, Volume 20, Issue 5-6, pp. 310 - 316
C9orf72 hexanucleotide repeat expansions are the most common known cause of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). Genetic... 
genetic counseling | genetics | intermediate expansions | repeat expansions | Genetic testing | C9orf72 | laboratory methods
Journal Article
NeuroImage: Clinical, ISSN 2213-1582, 2019, Volume 24, pp. 101953 - 101953
To construct a clinical diagnostic biomarker using state-of-the-art microstructural MRI in the motor cortex of people with amyotrophic lateral sclerosis (ALS).... 
Diffusion kurtosis imaging (additional) | Amyotrophic lateral sclerosis | Magnetic resonance imaging | Motor cortex | DWI | Index Medicus
Journal Article
Amyotrophic lateral sclerosis & frontotemporal degeneration, 03/2019, p. 1
C9orf72 hexanucleotide repeat expansions are the most common known cause of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). Genetic... 
Journal Article
by van Rheenen, Wouter and Shatunov, Aleksey and Dekker, Annelot M and McLaughlin, Russell L and Diekstra, Frank P and Pulit, Sara L and van der Spek, Rick A. A and Võsa, Urmo and de Jong, Simone and Robinson, Matthew R and Yang, Jian and Fogh, Isabella and van Doormaal, Perry Tc and Tazelaar, Gijs H. P and Koppers, Max and Blokhuis, Anna M and Sproviero, William and Jones, Ashley R and Kenna, Kevin P and van Eijk, Kristel R and Harschnitz, Oliver and Schellevis, Raymond D and Brands, William J and Medic, Jelena and Menelaou, Anoniki and Vajda, Alice and Ticozzi, Nicola and Lin, Kuang and Rogelj, Boris and Vrabec, Katarina and Ravnik-Glavač, Metka and Koritnik, Blaž and Zidar, Janez and Leonardis, Lea and Grošelj, Leja Dolenc and Millecamps, Stéphanie and Salachas, François and Meininger, Vincent and de Carvalho, Mamede and Pinto, Susana and Mora, Jesus S and Rojas-García, Ricardo and Polak, Meraida and Chanan, Siddharthan and Colville, Shuna and Swingler, Robert and Morrison, Karen E and Shaw, Pamela J and Hardy, John and Orrell, Richard W and Pittman, Alan and Sidle, Katie and Fratta, Pietro and Malaspina, Anea and Topp, Simon and Petri, Susanne and Abdulla, Susanne and pper, Carsten and Sendtner, Michael and Meyer, Thomas and Ophoff, Roel A and Staats, Kim A and Wiedau-Pazos, Martina and Lomen-Hoerth, Catherine and van Deerlin, Vivianna M and Trojanowski, John Q and Elman, Lauren and McCluskey, Leo and Basak, A. Nazli and Tunca, Ceren and Hamzeiy, Hamid and Parman, Yesim and Meitinger, Thomas and Lichtner, Peter and Radivojkov-Blagojevic, Milena and Anes, Christian R and Maurel, Cindy and Bensimon, Gilbert and Landwehrmeyer, Bernhard and Brice, Alexis and Payan, Christine A. M and Saker-Delye, Safaa and Dürr, Alexana and Wood, Nicholas W and Tittmann, Lukas and Lieb, Wolfgang and Franke, Ane and Rietschel, Marcella and Cichon, Sven and Nöthen, Markus M and Amouyel, Philippe and Tzourio, Christophe and Dartigues, Jean-François and Uitterlinden, Ane G and Rivadeneira, Fernando and Estrada, Karol and Hofman, Albert and Curtis, Charles and Blauw, Hylke M and van der Kooi, Anneke J and ... and PARALS Registry and FALS Sequencing Consortium and SLALOM Grp and SLAGEN Consortium and NNIPPS Study Grp and SLAP Registry and SLALOM Group and NNIPPS Study Group and Medicinska fakulteten and Institutionen för farmakologi och klinisk neurovetenskap and Klinisk neurovetenskap and Umeå universitet
Nature genetics, ISSN 1061-4036, 2016, Volume 48, Issue 9, pp. 1043 - 1048
Journal Article
Journal of Parkinson's Disease, ISSN 1877-7171, 2013, Volume 3, Issue 2, pp. 145 - 152
A significant number of autosomal dominantly inherited Parkinson's disease (PD) cases are due to mutations in the leucine-rich repeat kinase 2 (LRRK2) gene. In... 
Parkinson's disease | antibody. LRRK2 | inflammation | Kinase | neurodegeneration | monocyte | immunity | phosphorylation | lymphocyte | KINASE-ACTIVITY | CROHNS-DISEASE | CYTOPLASMIC LOCALIZATION | NEUROSCIENCES | MUTANTS | INFLAMMATORY-BOWEL-DISEASE | INHIBITION | GENE | 14-3-3 BINDING | NEURONS | MUTATIONS
Journal Article
Scientific reports, ISSN 2045-2322, 06/2019, Volume 9, Issue 1, pp. 8254 - 17
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterised by the loss of upper and lower motor neurons. ALS exhibits high... 
Motor neurons | Phenotypes | Immune response | Neurodegenerative diseases | Phenotypic variations | Amyotrophic lateral sclerosis | Superoxide dismutase | Ribonucleic acid--RNA | Gene expression | Receptor activity modifying proteins | Sclerosis | Protein folding | DNA methylation | Methylation | Twins
Journal Article
ISSN 0885-3185, 2010
MtDNA haplogroups J and K have been associated with a decreased risk of developing Parkinson's disease (PD). To confirm this finding, we compared the... 
Eskitis Cell and Molecular Therapies | Neurology and Neuromuscular Diseases | 110904 | Science, Environment, Engineering and Technology
Journal Article
Nature Communications [E], ISSN 2041-1723, 09/2017, Volume 8, Issue 1, pp. 611 - 7
Journal Article
SCIENCE TRANSLATIONAL MEDICINE, ISSN 1946-6234, 10/2018, Volume 10, Issue 465, p. eaah4066
Parkinson's disease (PD) is characterized by a profound loss of dopaminergic neurons in the substantia nigra, accompanied by chronic neuroinflammation,... 
MEDICINE, RESEARCH & EXPERIMENTAL | MICROGLIAL ACTIVATION | OLFACTORY-BULB | NEUROINFLAMMATION | ALZHEIMERS-DISEASE | AMYLOID-BETA | INTERLEUKIN-1-BETA | NEURONS | NLRP3 INFLAMMASOME | LESIONS | PARKINSONS-DISEASE | CELL BIOLOGY
Journal Article