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Frontiers in Cellular Neuroscience, ISSN 1662-5102, 11/2018, Volume 12, pp. 461 - 461
Journal Article
Clinical Science, ISSN 0143-5221, 07/2018, Volume 132, Issue 13, pp. 1403 - 1415
It is well established that Smad3 is a key downstream effector of transforming growth factor-beta (TGF-beta) signaling in tissue fibrogenesis. We reported here... 
MEDICINE, RESEARCH & EXPERIMENTAL | GROWTH-FACTOR-BETA | IN-VITRO | TGF-BETA | SMAD3 | DISRUPTION | UNILATERAL URETERAL OBSTRUCTION | INFLAMMATION | II RECEPTOR | DIABETIC-NEPHROPATHY | INHIBITOR | Index Medicus
Journal Article
The Journal of Physiology, ISSN 0022-3751, 08/2018, Volume 596, Issue 16, pp. 3493 - 3503
Journal Article
Journal of Physiology, ISSN 0022-3751, 08/2018, Volume 596, Issue 16, p. 3493
Transforming growth factor-[beta] (TGF-[beta]) is the key player in tissue fibrosis. However, antifibrotic therapy targeting this multifunctional protein may... 
Chronic kidney failure | RNA | Analysis | Fibrosis | Physiological aspects | Development and progression | Bone morphogenetic proteins | Genetic transcription | Transforming growth factors
Journal Article
Separation Science and Technology, ISSN 0149-6395, 10/2018, Volume 53, Issue 15, pp. 2418 - 2426
Journal Article
PLoS ONE, ISSN 1932-6203, 07/2013, Volume 8, Issue 7, pp. e70195 - e70195
Journal Article
Clinical and Experimental Pharmacology and Physiology, ISSN 0305-1870, 11/2014, Volume 41, Issue 11, p. 921
  Summary Transforming growth factor (TGF)-[beta]1 signals through downstream Smad-dependent and -independent pathways to exert its biological actions. It has... 
Psoriasis | Dermatology | Analysis | Formulae, receipts, prescriptions | Bone morphogenetic proteins | Dermatologic agents | Skin | Genetic engineering | T cells | Transforming growth factors | Medical research | Transgenic animals | Rodents
Journal Article
Advanced Functional Materials, ISSN 1616-301X, 09/2013, Volume 23, Issue 35, pp. 4345 - 4353
Journal Article
PLoS ONE, ISSN 1932-6203, 03/2014, Volume 9, Issue 3, p. e90807
Increasing evidence shows that TGF-[beta]1 is a key mediator in diabetic nephropathy (DN) and induces renal fibrosis positively by Smad3 but negatively by... 
Fibronectins | Streptozocin | Blood sugar | Collagen | Body weight | Diabetic nephropathies | Bone morphogenetic proteins | Medicine, Chinese | Transforming growth factors | Health aspects
Journal Article
Journal Article
Tetrahedron Letters, ISSN 0040-4039, 10/2013, Volume 54, Issue 44, p. 5857
A series of functionalized spiro 1,4-benzoxazine oxindole derivatives were obtained in moderate to good yields via a domino Mannich-alkylation of... 
Schiff bases
Journal Article
Tetrahedron Letters, ISSN 0040-4039, 10/2013, Volume 54, Issue 44, pp. 5857 - 5860
A series of functionalized spiro 1,4-benzoxazine oxindole derivatives were obtained in moderate to good yields via a domino Mannich-alkylation of... 
Construction | Imines | Tetrahedrons | Derivatives
Journal Article
Hypertension, ISSN 0194-911X, 10/2009, Volume 54, Issue 4, pp. 877 - 884
Journal Article
PLoS ONE, ISSN 1932-6203, 02/2012, Volume 7, Issue 2, pp. e31350 - e31350
Liver fibrosis is a major cause of liver failure, but treatment remains ineffective. In the present study, we investigated the mechanisms and... 
RENAL FIBROSIS | CELLS | GROWTH-FACTOR-BETA | CENTELLA-ASIATICA | RAT | HEPATIC FIBROGENESIS | MULTIDISCIPLINARY SCIENCES | MICE | GENE-TRANSFER | EXPRESSION | SMAD7 | Immunohistochemistry | Liver - pathology | Carbon Tetrachloride | Hepatic Stellate Cells - metabolism | Male | Liver - physiopathology | Gene Knockdown Techniques | Liver - drug effects | Time Factors | Liver Cirrhosis - metabolism | Phosphorylation - drug effects | Real-Time Polymerase Chain Reaction | Hepatic Stellate Cells - pathology | Hepatic Stellate Cells - drug effects | Liver Function Tests | Cell Line | Collagen Type I - metabolism | Liver Cirrhosis - prevention & control | Liver - metabolism | Rats | Pentacyclic Triterpenes - pharmacology | Pentacyclic Triterpenes - therapeutic use | Rats, Sprague-Dawley | Blotting, Western | Up-Regulation - drug effects | Transforming Growth Factor beta - pharmacology | Animals | Signal Transduction - drug effects | Liver Cirrhosis - pathology | Liver Cirrhosis - physiopathology | Smad Proteins - metabolism | Transforming Growth Factor beta - metabolism | Liver diseases | Collagen | Liver | Carbon tetrachloride | Fibrosis | Bone morphogenetic proteins | Research | Transforming growth factors | Health aspects | Health sciences | Smad protein | Transformation | Transforming growth factor-b | Cytotoxicity | Smooth muscle | Activation | Dosage | Antioxidants | Cell activation | Actin | Smad2 protein | Rodents | Fibroblasts | Inhibition | Drug dosages | Microwaves | Medical research | Antigens | Connective tissue growth factor | Pharmacology | Chemical compounds | Disease control | Medicine | Studies | Hospitals | Acids | Smad7 protein | Laboratory animals | Index Medicus
Journal Article