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1. Full Text G-quadruplexes and G-quadruplex ligands: targets and tools in antiviral therapy
by Ruggiero, Emanuela and Richter, Sara N
Nucleic Acids Research, ISSN 0305-1048, 04/2018, Volume 46, Issue 7, pp. 3270 - 3283
Abstract G-quadruplexes (G4s) are non-canonical nucleic acids secondary structures that form within guanine-rich strands of regulatory genomic regions. G4s... 
TELOMERIC G-QUADRUPLEX | HUMAN GENOME | LONG TERMINAL REPEAT | DNA G-QUADRUPLEX | STRUCTURAL BASIS | HYBRID G-QUADRUPLEX | BIOCHEMISTRY & MOLECULAR BIOLOGY | IN-VIVO | STRUCTURE-BASED DESIGN | INHIBITS TUMOR-GROWTH | VIRUS IMMUNE EVASION | Zika Virus - genetics | Antiviral Agents - therapeutic use | Virus Replication - genetics | Humans | Ebolavirus - pathogenicity | Ebolavirus - genetics | Promoter Regions, Genetic - genetics | Genome, Human - genetics | Zika Virus Infection - virology | Zika Virus Infection - genetics | Hemorrhagic Fever, Ebola - virology | G-Quadruplexes | Ligands | Hemorrhagic Fever, Ebola - genetics | Zika Virus - pathogenicity | Telomere - genetics | Virus Latency - genetics | Survey and Summary
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2. Full Text Survey and summary G-quadruplexes and G-quadruplex ligands: Targets and tools in antiviral therapy
by Ruggiero, Emanuela and Richter, Sara N
Nucleic Acids Research, ISSN 0305-1048, 2018, Volume 46, Issue 7, pp. 3270 - 3283
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3. Full Text The Novel Estrogen Receptor, G Protein-Coupled Receptor 30, Mediates the Proliferative Effects Induced by 17β-Estradiol on Mouse Spermatogonial GC-1 Cell Line
by Sirianni, Rosa and Chimento, Adele and Ruggiero, Carmen and De Luca, Arianna and Lappano, Rosamaria and Andò, Sebastiano and Maggiolini, Marcello and Pezzi, Vincenzo
Endocrinology, ISSN 0013-7227, 10/2008, Volume 149, Issue 10, pp. 5043 - 5051
Many studies have indicated that estrogens could have a role in the regulation of testicular function. However, it remains uncertain whether estrogens are able... 
REGULATED KINASE | GROWTH-FACTOR RECEPTOR | BREAST-CANCER CELLS | PERINATAL LIFE | REPRODUCTIVE-TRACT | GERM-CELLS | ANDROGEN RECEPTORS | ENDOCRINOLOGY & METABOLISM | SELECTIVE LIGAND | RANA-ESCULENTA | MICE LACKING
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4. Full Text The cellular protein hnRNP A2/B1 enhances HIV-1 transcription by unfolding LTR promoter G-quadruplexes
by Scalabrin, Matteo and Frasson, Ilaria and Ruggiero, Emanuela and Perrone, Rosalba and Tosoni, Elena and Lago, Sara and Tassinari, Martina and Palù, Giorgio and Richter, Sara N
Scientific Reports, ISSN 2045-2322, 03/2017, Volume 7, Issue 1, p. 45244
G-quadruplexes are four-stranded conformations of nucleic acids that act as cellular epigenetic regulators. A dynamic G-quadruplex forming region in the HIV-1... 
ELEMENT | TERMINAL REPEAT PROMOTER | DNA | DESTABILIZATION | MULTIDISCIPLINARY SCIENCES | ZINC-FINGER | SEQUENCE | GENOMIC RNA | IDENTIFICATION | MAMMALIAN-CELLS | BINDING | Promoter Regions, Genetic | Gene Expression Regulation, Viral | Humans | Transcriptional Activation | HEK293 Cells | Protein Binding | G-Quadruplexes | Heterogeneous-Nuclear Ribonucleoprotein Group A-B - metabolism | HIV-1 - genetics | Terminal Repeat Sequences | Proteins | Transcription | Oligonucleotides | Latent infection | Mass spectroscopy | Surface plasmon resonance | Fluorescence resonance energy transfer | Drug development | Thermal stability | nucleolin
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5. Full Text The KDEL receptor couples to Gαq/11 to activate Src kinases and regulate transport through the Golgi
by Giannotta, Monica and Ruggiero, Carmen and Grossi, Mauro and Cancino, Jorge and Capitani, Mirco and Pulvirenti, Teodoro and Consoli, Grazia Maria Letizia and Geraci, Corrada and Fanelli, Francesca and Luini, Alberto and Sallese, Michele
The EMBO Journal, ISSN 0261-4189, 06/2012, Volume 31, Issue 13, pp. 2869 - 2881
Membrane trafficking involves large fluxes of cargo and membrane across separate compartments. These fluxes must be regulated by control systems to maintain... 
Golgi complex | KDEL receptor | endomembrane signalling | G‐protein‐coupled receptor | G-protein-coupled receptor | Computer Simulation | Humans | src-Family Kinases - metabolism | Endoplasmic Reticulum - metabolism | Golgi Apparatus - metabolism | Protein Transport - physiology | Signal Transduction - physiology | HeLa Cells | GTP-Binding Protein alpha Subunits, Gq-G11 - metabolism | Receptors, Peptide - metabolism
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6. Le Prix du froment en France au temps de la monnaie stable (1726-1913), réédition de grands tableaux statistiques
: Introduction et notes par Ernest Labrousse ... Ruggiero Romana ... F.-G. Dreyfus
by Labrousse, Camille Ernest, 1895 and Romano, Ruggiero and Dreyfus, François G
1970, Monnaie, prix, conjoncture, 9, 246
Prices | France | Wheat
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7. Full Text New genetic loci link adipose and insulin biology to body fat distribution
by Shungin, Dmitry and Winkler, Thomas W and Croteau-Chonka, Damien C and Ferreira, Teresa and Locke, Adam E and Mägi, Reedik and Strawbridge, Rona J and Pers, Tune H and Fischer, Krista and Justice, Anne E and Workalemahu, Tsegaselassie and Wu, Joseph M. W and Buchkovich, Martin L and Heard-Costa, Nancy L and Roman, Tamara S and ng, Alexander W and Song, Ci and Gustafsson, Stefan and Day, Felix R and Esko, Tonu and Fall, Tove and Kutalik, Zoltán and Luan, Jian'an and Randall, Joshua C and Scherag, Ané and Vedantam, Sailaja and Wood, Anew R and Chen, Jin and Fehrmann, Rudolf and Karjalainen, Juha and Kahali, Bratati and Liu, Ching-Ti and Schmidt, Ellen M and Absher, Devin and Amin, Najaf and Anderson, Denise and Beekman, Marian and Bragg-Gresham, Jennifer L and Buyske, Steven and Demirkan, Ayse and Ehret, Georg B and Feitosa, Mary F and Goel, Anuj and Jackson, Anne U and Johnson, Toby and Kleber, Marcus E and Kristiansson, Kati and Mangino, Massimo and Mateo Leach, Irene and Medina-Gomez, Carolina and Palmer, Cameron D and Pasko, Dorota and Pechlivanis, Sonali and Peters, Marjolein J and Prokopenko, Inga and Stančáková, Alena and Ju Sung, Yun and Tanaka, Toshiko and Teumer, Alexander and van Vliet-Ostaptchouk, Jana V and Yengo, Loïc and Zhang, Weihua and Albrecht, Eva and Ärnlöv, Johan and Arscott, Gillian M and Bandinelli, Stefania and Barrett, Amy and Bellis, Claire and Bennett, Amanda J and Berne, Christian and Blüher, Matthias and Böhringer, Stefan and Bonnet, Fabrice and Böttcher, Yvonne and Bruinenberg, Marcel and Carba, Delia B and Caspersen, Ida H and Clarke, Robert and Daw, E. Warwick and Deelen, Joris and Deelman, Ewa and Delgado, Graciela and Doney, Alex S. F and Eklund, Niina and Erdos, Michael R and Estrada, Karol and Eury, Elodie and Frieich, Nele and Garcia, Melissa E and Gieaitis, Vilmantas and Gigante, Bruna and Go, Alan S and Golay, Alain and Grallert, Harald and Grammer, Tanja B and Gräßler, Jürgen and Grewal, Jagvir and Groves, Christopher J and Haller, Toomas and Hallmans, Goran and ... and PAGE Consortium and LifeLines Cohort Study and CARDIOGRAMplusC4D Consortium and MuTHER Consortium and ICBP and ADIPOGEN Consortium and CKDGen Consortium and GEFOS Consortium and Int Endogene Consortium and GENIE Consortium and MAGIC Investigators and ReproGen Consortium and GLGC and ADIPOGen Consortium and International Endogene Consortium and The PAGE Consortium and The International Endogene Consortium and The MAGIC Investigators and The ReproGen Consortium and The CKDGen Consortium and The ADIPOGen Consortium and The ICBP and The CARDIOGRAMplusC4D Consortium and The GENIE Consortium and The GLGC and The GEFOS Consortium and The MuTHER Consortium and The LifeLines Cohort Study and Högskolan Dalarna and Akademin Utbildning, hälsa och samhälle and Medicinsk vetenskap
Nature, ISSN 0028-0836, 2015, Volume 518, Issue 7538, pp. 187 - U378
Body fat distribution is a heritable trait and a well-established predictor of adverse metabolic outcomes, independent of overall adiposity. To increase our... 
HUMAN HEIGHT | ABDOMINAL ADIPOSITY | MULTIDISCIPLINARY SCIENCES | COMMON SNPS | SUSCEPTIBILITY LOCI | GLYCEMIC TRAITS | FALSE DISCOVERY | MESENCHYMAL STEM-CELLS | GENOME-WIDE ASSOCIATION | ADIPOGENIC DIFFERENTIATION | SEXUAL-DIMORPHISM | Body Mass Index | Genome-Wide Association Study | Age Factors | Neovascularization, Physiologic - genetics | Epigenesis, Genetic | Humans | Male | Continental Population Groups - genetics | Sex Characteristics | Obesity - genetics | Europe - ethnology | Genome, Human - genetics | Adipose Tissue - metabolism | Insulin - metabolism | Models, Biological | Adipocytes - metabolism | Insulin Resistance - genetics | Polymorphism, Single Nucleotide - genetics | Female | Body Fat Distribution | Transcription, Genetic - genetics | Adipogenesis - genetics | Waist-Hip Ratio | Quantitative Trait Loci - genetics | Adipose tissues | Quantitative trait loci | Genetic research | Genetic aspects | Research | Metabolism | Health aspects | Studies | Body mass index | Genealogy | Body fat | Insulin resistance | Genetics | Genomes | Abdomen | Meta-analysis | Life Sciences | Adipocytes/metabolism Adipogenesis/genetics Adipose Tissue/metabolism Age Factors Body Fat Distribution Body Mass Index Continental Population Groups/genetics Epigenesis, Genetic Europe/ethnology Female Genome, Human/genetics Genome-Wide Association Study Humans Insulin/metabolism Insulin Resistance/genetics Male Models, Biological Neovascularization, Physiologic/genetics Obesity/genetics Polymorphism, Single Nucleotide/genetics Quantitative Trait Loci/genetics Sex Characteristics Transcription, Genetic/genetics Waist-Hip Ratio | Clinical Medicine | Hälsa och välfärd | Medical and Health Sciences | Klinisk medicin | Medicin och hälsovetenskap | Health and Welfare
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8. Full Text Genome-wide association analyses identify 18 new loci associated with serum urate concentrations
by Kottgen, A and Albrecht, E and Teumer, A and Vitart, V and Krumsiek, J and Hundertmark, C and Pistis, G and Ruggiero, D and O'Seaghdha, C.M and Haller, T and Yang, Q and Johnson, A.D and Kutalik, Z and Smith, A.V and Shi, J.L and Struchalin, M and Middelberg, R.P.S and Brown, M.J and Gaffo, A.L and Pirastu, N and Li, G and Hayward, C and Zemunik, T and Huffman, J and Yengo, L and Zhao, J.H and Demirkan, A and Feitosa, M.F and Liu, X and Malerba, G and Lopez, L.M and van der Harst, P and Li, X.Z and Kleber, M.E and Hicks, A.A and Nolte, I.M and Johansson, A and Murgia, F and Wild, S.H and Bakker, S.J.L and Peden, J.F and Dehghan, A and Steri, M and Tenesa, A and Lagou, V and Salo, P and Mangino, M and Rose, L.M and Lehtimaki, T and Woodward, O.M and Okada, Y and Tin, A and Muller, C and Oldmeadow, C and Putku, M and Czamara, D and Kraft, P and Frogheri, L and Thun, G.A and Grotevendt, A and Gislason, G.K and Harris, T.B and Launer, L.J and McArdle, P and Shuldiner, A.R and Boerwinkle, E and Coresh, J and Schmidt, H and Schallert, M and Martin, N.G and Montgomery, G.W and Kubo, M and Nakamura, Y and Tanaka, T and Munroe, P.B and Samani, N.J and Jacobs, D.R and Liu, K and d'Adamo, P and Ulivi, S and Rotter, J.I and Psaty, B.M and Vollenweider, P and Waeber, G and Campbell, S and Devuyst, O and Navarro, P and Kolcic, I and Hastie, N and Balkau, B and Froguel, P and Esko, T and Salumets, A and Khaw, K.T and Langenberg, C and Wareham, N.J and Isaacs, A and Kraja, A and Zhang, Q.Y and Penninx, B.W.J.H and ... and DIAGRAM Consortium and MAGIC Consortium and LifeLines Cohort Study and CARDIoGRAM Consortium and ICBP Consortium and Medicinska fakulteten and Medicinska och farmaceutiska vetenskapsområdet and Institutionen för immunologi, genetik och patologi and Medicinska och farmaceutiska vetenskapsområdet, centrumbildningar mm and Genomik and Uppsala universitet and Uppsala kliniska forskningscentrum (UCR)
Nature Genetics, ISSN 1061-4036, 2013, Volume 45, Issue 2, pp. 145 - 154
Elevated serum urate concentrations can cause gout, a prevalent and painful inflammatory arthritis. By combining data from >140,000 individuals of European... 
CARDIOVASCULAR-DISEASE RISK | POPULATION | METABOLIC SYNDROME | HYPERURICEMIA | TRANSPORTER | MOLECULAR PHYSIOLOGY | GOUT | GENETICS & HEREDITY | GENETIC-LOCI | IDENTIFICATION | URIC-ACID LEVELS | Genome-Wide Association Study | Gene Frequency | Humans | Genetic Loci - genetics | European Continental Ancestry Group | Signal Transduction - genetics | Analysis of Variance | Inhibins - metabolism | Glucose - metabolism | Polymorphism, Single Nucleotide - genetics | Gout - genetics | Inhibins - genetics | Uric Acid - blood | Gout - blood | Glucose metabolism | Inhibin | Physiological aspects | Genetic aspects | Arthritis | Research | Uric acid | Health aspects | Studies | Gene loci | Statistical methods | Genomes | Diet | Medical and Health Sciences | Medicin och hälsovetenskap
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