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European Journal of Immunology, ISSN 0014-2980, 09/2015, Volume 45, Issue 9, pp. 2615 - 2627
Delta‐like protein 1 (DLK1) is a noncanonical ligand that inhibits NOTCH1 receptor activity and regulates multiple differentiation processes. In macrophages,... 
NOTCH signaling | TLR | DLK1 | Cytokine | Inflammatory inhibitor | Macrophage | STEM-CELLS | COMPLEX | PROTEIN | RECEPTOR | IMMUNOLOGY | REGULATOR | PATHWAY | GENE-EXPRESSION | DIFFERENTIATION | UP-REGULATION | Inflammation - pathology | Interferon-beta - immunology | Interleukin-12 - genetics | Humans | Transcription Factor RelB - immunology | Tumor Necrosis Factor-alpha - genetics | Interleukin-23 - genetics | U937 Cells | Tumor Necrosis Factor-alpha - immunology | Interferon-beta - genetics | Cell Differentiation | Toll-Like Receptor 3 - genetics | Macrophages - immunology | Transcription Factor RelB - genetics | Cell Line | Signal Transduction | Gene Expression Regulation | Intercellular Signaling Peptides and Proteins - genetics | Interferon Regulatory Factors - genetics | Receptor, Notch1 - immunology | Toll-Like Receptor 4 - genetics | Toll-Like Receptor 3 - immunology | Inflammation - immunology | Toll-Like Receptor 4 - immunology | Macrophages - cytology | STAT1 Transcription Factor - genetics | Interleukin-23 - immunology | STAT1 Transcription Factor - immunology | Macrophage Activation | Mice, Knockout | Interferon Regulatory Factors - immunology | Animals | Interleukin-12 - immunology | Inflammation - genetics | Mice | Receptor, Notch1 - genetics | Intercellular Signaling Peptides and Proteins - immunology | Proteins | Macrophages | Septic shock | Rodents
Journal Article
Journal Article
European Journal of Immunology, ISSN 0014-2980, 09/2009, Volume 39, Issue 9, pp. 2556 - 2570
Macrophages present different Notch receptors and ligands on their surface. Following macrophage activation by LPS or other TLR ligands, Notch1 expression is... 
Macrophages | NF‐κB | Notch | NF-κB | TARGET | TRANSCRIPTION | INVOLVEMENT | ALPHA | IMMUNOLOGY | NF-kappa B | INTERFERON-GAMMA | PRE-TCR | DIFFERENTIATION | T-CELL DEVELOPMENT | EXPRESSION | INTERLEUKIN-6 GENE
Journal Article
Experimental Cell Research, ISSN 0014-4827, 2005, Volume 303, Issue 2, pp. 343 - 359
The protein dlk, encoded by the Dlk1 gene, belongs to the Notch epidermal growth factor (EGF)-like family of receptors and ligands, which participate in cell... 
dlk | Notch1 | Yeast two-hybrid system | Luciferase | Balb/c 14 | 3T3-L1 | CSL/RBP-Jk/CBF-1 | INHIBITS ADIPOCYTE DIFFERENTIATION | NEURONAL DIFFERENTIATION | CELL BIOLOGY | NUCLEAR-LOCALIZATION | DELTA-LIKE PROTEIN | ONCOLOGY | FACTOR-I PREF-1 | SIGNALING PATHWAY | luciferase | yeast two-hybrid system | HOMEOTIC PROTEIN DLK | T-CELL DEVELOPMENT | GAMMA-SECRETASE | HUMAN HOMOLOG | Transcription Factor HES-1 | Transcription Factors - chemistry | Homeodomain Proteins - metabolism | Humans | DNA, Antisense - genetics | Luciferases - genetics | Repetitive Sequences, Amino Acid | Transfection | Base Sequence | Epidermal Growth Factor - chemistry | Receptors, Cell Surface - chemistry | Membrane Proteins - metabolism | Genes, Reporter | Basic Helix-Loop-Helix Transcription Factors | Recombinant Proteins - metabolism | Cell Line | Epidermal Growth Factor - genetics | Membrane Proteins - genetics | Gene Expression Regulation | Intracellular Signaling Peptides and Proteins | Receptors, Cell Surface - metabolism | Recombinant Proteins - chemistry | Epidermal Growth Factor - metabolism | Recombinant Proteins - genetics | Transcription Factors - genetics | 3T3-L1 Cells | Homeodomain Proteins - chemistry | Homeodomain Proteins - genetics | Transcription Factors - metabolism | Two-Hybrid System Techniques | Animals | Membrane Proteins - chemistry | Mice | Receptor, Notch1 | In Vitro Techniques | Receptors, Cell Surface - genetics | Monoclonal antibodies | Biological products | Epidermal growth factor | CARBON 14 | IN VIVO | 60 APPLIED LIFE SCIENCES | LUCIFERASE | GROWTH FACTORS | PEPTIDES | LIGANDS | CULTURE MEDIA | GENES | YEASTS | CELL DIFFERENTIATION | GENE REGULATION | RECEPTORS | HYBRID SYSTEMS
Journal Article
Cancer Letters, ISSN 0304-3835, 2017, Volume 399, pp. 74 - 81
Abstract The E1a gene from adenovirus has become a major tool in cancer research. Since the discovery of E1a, it has been proposed to be an oncogene, becoming... 
Hematology, Oncology and Palliative Medicine | Tumour suppressor | Transgenic mouse | E1a | Gene therapy | Oncogene | Skin carcinogenesis | TRANSFORMATION | CHEMICAL CARCINOGENESIS | INDUCTION | CANCER | PRIMARY EPITHELIAL-CELLS | H-RAS | ONCOLOGY | ADENOVIRUS E1A | CELLULAR-PROTEINS | GENE-TRANSFER | EXPRESSION | Tetradecanoylphorbol Acetate | Cell Proliferation | Humans | Melanoma, Experimental - metabolism | Melanoma, Experimental - prevention & control | Skin Neoplasms - prevention & control | Transfection | Time Factors | Adenovirus E1A Proteins - metabolism | Cell Transformation, Neoplastic - genetics | Tumor Suppressor Proteins - genetics | Female | Skin Neoplasms - pathology | Tumor Suppressor Proteins - metabolism | Signal Transduction | HCT116 Cells | Mice, Inbred C57BL | Melanoma, Experimental - pathology | Mice, Transgenic | Tumor Burden | Cell Transformation, Neoplastic - metabolism | Skin Neoplasms - metabolism | Animals | Melanoma, Experimental - genetics | Mice, Nude | Adenovirus E1A Proteins - genetics | Skin Neoplasms - genetics | 9,10-Dimethyl-1,2-benzanthracene | Mice, Inbred BALB C | Cell Transformation, Neoplastic - pathology | Keratin | Embryonic development | Genetic engineering | Analysis | Adenoviruses | Cancer | Dermatology | Formulae, receipts, prescriptions | Dermatologic agents | Skin | Tumors | Index Medicus
Journal Article
Neoplasia, ISSN 1476-5586, 2013, Volume 15, Issue 6, pp. 649 - IN17
Journal Article
Journal of Bone and Mineral Research, ISSN 0884-0431, 07/2011, Volume 26, Issue 7, pp. 1457 - 1471
Journal Article