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European Journal of Medicinal Chemistry, ISSN 0223-5234, 12/2019, Volume 183, p. 111704
Curcumin is a small organic molecule with pleiotropic biological activities. However, its multiple structural-pharmacokinetic challenges prevent its... 
Bioactivity | Asymmetric curcumin | Synthesis | Monoketone | Diketone
Journal Article
Biochemical Pharmacology, ISSN 0006-2952, 09/2017, Volume 139, pp. 114 - 114
To access, purchase, authenticate, or subscribe to the full-text of this article, please visit this link: http://dx.doi.org/10.1016/j.bcp.2017.06.081 
Endometrial cancer | Hormone therapy | Phenylalanine | RNA | Oncology, Experimental | Estrogen | Postmenopausal women | Research | Tamoxifen | Gene expression | Alkaloids | Analysis | Cancer
Journal Article
Asian Journal of Organic Chemistry, ISSN 2193-5807, 08/2019, Volume 8, Issue 8, pp. 1174 - 1193
In this Minireview, we discuss some of the important palladium‐catalysed cross‐coupling reactions utilised in the synthesis of the enone system of chalcones.... 
chalcones | palladium | C−C coupling | enones | C-C coupling | N-VINYLPYRIDINIUM | IN-SILICO | EX-SITU | CHEMISTRY, ORGANIC | FLAVONOIDS | CARBONYLATIVE HECK REACTIONS | ARYL BROMIDES | TETRAFLUOROBORATE SALTS | ACID-CHLORIDES | ISOMERIZATION SYNTHESIS | BIOLOGICAL-ACTIVITY
Journal Article
Bioorganic & Medicinal Chemistry Letters, ISSN 0960-894X, 05/2016, Volume 26, Issue 10, pp. 2531 - 2538
Journal Article
Medicinal Chemistry Research, ISSN 1054-2523, 12/2017, Volume 26, Issue 12, pp. 3323 - 3335
Curcumin is an important molecule found in turmeric plants and has been reported to exhibit some profound anti-inflammatory activities by interacting with... 
Biochemistry, general | Biomedicine | MAPK phosphorylation | COX-2 mRNA expression | Dynamic simulation | Unsymmetrical dicarbonyl curcumin derivatives | Pharmacology/Toxicology | Molecular | Prostaglandin E 2 | Cell Biology | Prostaglandin E
Journal Article
Journal Article
Chemical Biology & Drug Design, ISSN 1747-0277, 03/2019, Volume 93, Issue 3, pp. 222 - 231
Hormone replacement therapy has been a conventional treatment for postmenopausal symptoms in women. However, it has potential risks of breast and endometrial... 
TFF1 and PGR genes | mimosine | MCF‐7 cell line | oestrogenic activity | MCF-7 cell line | PLANT | CHEMISTRY, MEDICINAL | SEARCH | BIOCHEMISTRY & MOLECULAR BIOLOGY | VOLUME | PROLIFERATION | ANTAGONISM | GROMACS | DNA | GUI | EXPRESSION
Journal Article
International Journal of Pharmaceutics, ISSN 0378-5173, 07/2015, Volume 490, Issue 1-2, pp. 131 - 141
Journal Article
Bioorganic & Medicinal Chemistry Letters, ISSN 0960-894X, 08/2014, Volume 24, Issue 16, pp. 3826 - 3834
The discovery of potent inhibitors of prostaglandin E (PGE ) synthesis in recent years has been proven to be an important game changer in pharmaceutical... 
Prostaglandin E2 | ADMET prediction | Minor flavonoids | Single-crystal XRD | COX-2 inhibitor | Prenylated chalcone
Journal Article
Journal of Molecular Structure, ISSN 0022-2860, 11/2019, Volume 1196, pp. 844 - 850
The search of novel mPGES-1 inhibitors has recently intensified probably due to the superior safety in comparison to existing anti-inflammatory drugs. Although... 
PGE2 | mPGES-1 | PAINS | 3D-QSAR CoMFA | CRYSTAL-STRUCTURE | DOCKING | CHEMISTRY, PHYSICAL | IDENTIFICATION | DIARYLPENTANOID ANALOGS | PGE | PROSTAGLANDIN E-2 BIOSYNTHESIS | MURINE | ANTIOXIDANT | NITRIC-OXIDE | BIOLOGICAL EVALUATION | SIMULATIONS | Islamic schools | Drugstores | Interleukins | Pharmacy | Analysis
Journal Article
Journal Article
Jurnal Sains Kesihatan Malaysia, ISSN 1675-8161, 01/2018, Volume 16, Issue 1, pp. 135 - 143
Journal Article
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