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Oncogene, ISSN 0950-9232, 03/2019, Volume 38, Issue 10, pp. 1717 - 1733
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 04/2016, Volume 113, Issue 14, p. E2057
  Mutations in SMAD4 predispose to the development of gastrointestinal cancer, which is the third leading cause of cancer-related deaths. To identify genes... 
Proteins | Mutagenesis | Genes | Rodents | Mutation | Stomach cancer
Journal Article
Nature Genetics, ISSN 1061-4036, 05/2015, Volume 47, Issue 5, p. 486
  Although nearly half of human melanomas harbor oncogenic BRAF^sup V600E^ mutations, the genetic events that cooperate with these mutations to drive... 
Medical research | Laboratories | Rodents | Mutation | Kinases
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 11/2016, Volume 113, Issue 48, p. E7749
  Triple-negative breast cancer (TNBC) has the worst prognosis of any breast cancer subtype. To better understand the genetic forces driving TNBC, we performed... 
Mutagenesis | Medical prognosis | Rodents | Genetics | Oncology | Breast cancer | Gene expression
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 07/2016, Volume 113, Issue 29, p. 8290
  Prostate cancer (CaP) is the most common adult male cancer in the developed world. The paucity of biomarkers to predict prostate tumor biology makes it... 
Enzymes | Mutagenesis | Biomarkers | Biosynthesis | Metastasis | Prostate cancer
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 02/2015, Volume 112, Issue 6, p. E536
  BRAF (v-raf murine sarcoma viral oncogene homolog B) inhibitors elicit a transient anti-tumor response in ~80% of BRAF...-mutant melanoma patients that... 
Mutagenesis | Rodents | Melanoma | Models | Mutation | Gene expression
Journal Article
Journal Article
Journal Article
by Andrew V Biankin and Nicola Waddell and Karin S Kassahn and Marie-Claude Gingras and Lakshmi B Muthuswamy and Amber L Johns and David K Miller and Peter J Wilson and Ann-Marie Patch and Jianmin Wu and Richard A Morgan and Rita T Lawlor and Paola Capelli and Vincenzo Corbo and Maria Scardoni and Giampaolo Tortora and Margaret A Tempero and Karen M Mann and Nancy A Jenkins and Pedro A Perez-Mancera and David K Chang and David J Adams and David A Largaespada and Lodewyk F A Wessels and Alistair G Rust and Lincoln D Stein and David A Tuveson and Neal G Copeland and Elizabeth A Musgrove and Aldo Scarpa and James R Eshleman and Mark J Cowley and Thomas J Hudson and Robert L Sutherland and David A Wheeler and John V Pearson and John D McPherson and Richard A Gibbs and Sean M Grimmond and Brooke B Gardiner and Sarah Song and Ivon Harliwong and Senel Idrisoglu and Craig Nourse and Ehsan Nourbakhsh and Suzanne Manning and Shivangi Wani and Milena Gongora and Marina Pajic and Christopher J Scarlett and Anthony J Gill and Andreia V Pinho and Ilse Rooman and Matthew Anderson and Oliver Holmes and Conrad Leonard and Darrin Taylor and Scott Wood and Qinying Xu and Katia Nones and J Lynn Fink and Angelika Christ and Tim Bruxner and Nicole Cloonan and Gabriel Kolle and Felicity Newell and Mark Pinese and R Scott Mead and Jeremy L Humphris and Warren Kaplan and Marc D Jones and Emily K Colvin and Adnan M Nagrial and Emily S Humphrey and Angela Chou and Venessa T Chin and Lorraine A Chantrill and Amanda Mawson and Jaswinder S Samra and James G Kench and Jessica A Lovell and Roger J Daly and Neil D Merrett and Christopher Toon and Krishna Epari and Nam Q Nguyen and Andrew Barbour and Nikolajs Zeps and Nipun Kakkar and Fengmei Zhao and Yuan Qing Wu and Min Wang and Donna M Muzny and William E Fisher and F Charles Brunicardi and Sally E Hodges and Jeffrey G Reid and Jennifer Drummond and Kyle Chang and Yi Han and ...
Nature, ISSN 0028-0836, 11/2012, Volume 491, Issue 7424, p. 399
  Pancreatic cancer is a highly lethal malignancy with few effective therapies. We performed exome sequencing and copy number analysis to define genomic... 
Medical research | Pancreatic cancer | Genes | Mutation | Pancreas
Journal Article
Nature, ISSN 0028-0836, 01/2015, Volume 517, Issue 7535, pp. 489 - 492
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 11/2013, Volume 110, Issue 46, p. E4325
  The Sleeping Beauty (SB) transposon mutagenesis screen is a powerful tool to facilitate the discovery of cancer genes that drive tumorigenesis in mouse... 
Intervention | Mutagenesis | Genes | Rodents | Tumors | Cancer
Journal Article
by Biankin, Andrew V and Waddell, Nicola and Kassahn, Karin S and Gingras, Marie-Claude and Muthuswamy, Lakshmi B and Johns, Amber L and Miller, David K and Wilson, Peter J and Patch, Ann-Marie and Wu, Jianmin and Chang, David K and Cowley, Mark J and Gardiner, Brooke B and Song, Sarah and Harliwong, Ivon and Idrisoglu, Senel and Nourse, Craig and Nourbakhsh, Ehsan and Manning, Suzanne and Wani, Shivangi and Gongora, Milena and Pajic, Marina and Scarlett, Christopher J and Gill, Anthony J and Pinho, Andreia V and Rooman, Ilse and Anderson, Matthew and Holmes, Oliver and Leonard, Conrad and Taylor, Darrin and Wood, Scott and Xu, Qinying and Nones, Katia and Fink, J. Lynn and Christ, Angelika and Bruxner, Tim and Cloonan, Nicole and Kolle, Gabriel and Newell, Felicity and Pinese, Mark and Mead, R. Scott and Humphris, Jeremy L and Kaplan, Warren and Jones, Marc D and Colvin, Emily K and Nagrial, Adnan M and Humphrey, Emily S and Chou, Angela and Chin, Venessa T and Chantrill, Lorraine A and Mawson, Amanda and Samra, Jaswinder S and Kench, James G and Lovell, Jessica A and Daly, Roger J and Merrett, Neil D and Toon, Christopher and Epari, Krishna and Nguyen, Nam Q and Barbour, Andrew and Zeps, Nikolajs and Kakkar, Nipun and Zhao, Fengmei and Wu, Yuan Qing and Wang, Min and Muzny, Donna M and Fisher, William E and Brunicardi, F. Charles and Hodges, Sally E and Reid, Jeffrey G and Drummond, Jennifer and Chang, Kyle and Han, Yi and Lewis, Lora R and Dinh, Huyen and Buhay, Christian J and Beck, Timothy and Timms, Lee and Sam, Michelle and Begley, Kimberly and Brown, Andrew and Pai, Deepa and Panchal, Ami and Buchner, Nicholas and De Borja, Richard and Denroche, Robert E and Yung, Christina K and Serra, Stefano and Onetto, Nicole and Mukhopadhyay, Debabrata and Tsao, Ming-Sound and Shaw, Patricia A and Petersen, Gloria M and Gallinger, Steven and Hruban, Ralph H and Maitra, Anirban and Iacobuzio-Donahue, Christine A and Schulick, Richard D and Wolfgang, Christopher L and Morgan, Richard A and ... and Australian Pancreatic Canc Genome and Australian Pancreatic Cancer Genome Initiative
Nature, ISSN 0028-0836, 11/2012, Volume 491, Issue 7424, pp. 399 - 405
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 2/2015, Volume 112, Issue 6, pp. E536 - E545
Journal Article