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Nature Biotechnology, ISSN 1087-0156, 12/2015, Volume 33, Issue 12, pp. 1287 - 1292
There are numerous cell types with scarcely understood functions, whose interactions with the immune system are not well characterized. To facilitate their... 
MICROGLIA | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | TOLERANCE | RECEPTOR TRANSGENIC MICE | IN-VIVO | TISSUE | MONOCYTES | CENTRAL-NERVOUS-SYSTEM | EXPRESSION | LINEAGE | DELETION | Cell interaction | Fluorescent proteins | Genetic aspects | T cells | Gene expression | Observations | Health aspects | Antigen presentation | Protein expression | Cellular biology | Lymphocytes | Immune system
Journal Article
Nature Methods, ISSN 1548-7091, 08/2012, Volume 9, Issue 8, pp. 840 - 846
We introduce two large-scale resources for functional analysis of microRNA (miRNA): a decoy library for inhibiting miRNA function and a sensor library for... 
Animals | High-Throughput Screening Assays | MicroRNAs - antagonists & inhibitors | Gene Library | Humans | Biosensing Techniques | MicroRNAs - metabolism | MicroRNAs - genetics | Genetic Vectors - genetics | Fluorescence | Ribonucleic acid--RNA | Gene expression | Biosensors
Journal Article
Journal Article
Journal of Experimental Medicine, ISSN 0022-1007, 2014, Volume 211, Issue 4, pp. 669 - 683
Langerhans cell histiocytosis (LCH) is a clonal disorder with elusive etiology, characterized by the accumulation of CD207(+) dendritic cells (DCs) in... 
MEDICINE, RESEARCH & EXPERIMENTAL | ERDHEIM-CHESTER DISEASE | HISTIOCYTOSIS | THERAPY | GENE | BRAF V600E MUTATION | BIRBECK GRANULES | STEADY-STATE | LEUKEMIA | IMMUNOLOGY | LANGERHANS CELLS | VEMURAFENIB
Journal Article
Molecular Therapy, ISSN 1525-0016, 02/2012, Volume 20, Issue 2, pp. 254 - 266
Journal Article
Journal Article
Nature Immunology, ISSN 1529-2908, 01/2014, Volume 15, Issue 1, pp. 54 - 62
miR-126 is a microRNA expressed predominately by endothelial cells and controls angiogenesis. We found miR-126 was required for the innate response to... 
PLASMACYTOID DENDRITIC CELLS | SYSTEMIC-LUPUS-ERYTHEMATOSUS | ACTIVATION | VASCULAR INTEGRITY | MICRORNA MIR-126 | PREDENDRITIC CELLS | RECEPTOR | INDUCTION | IMMUNOLOGY | EXPRESSION | I INTERFERON | Oligonucleotide Array Sequence Analysis | Dendritic Cells - immunology | Humans | Immunity, Innate - genetics | Toll-Like Receptor 9 - genetics | Immunoblotting | MicroRNAs - metabolism | Transcriptome - immunology | NF-kappa B p50 Subunit - genetics | Vascular Endothelial Growth Factor Receptor-2 - immunology | Vascular Endothelial Growth Factor Receptor-2 - genetics | NF-kappa B p50 Subunit - immunology | Toll-Like Receptor 9 - immunology | HIV Infections - immunology | Flow Cytometry | Oligodeoxyribonucleotides - genetics | Toll-Like Receptor 7 - immunology | Dendritic Cells - metabolism | Toll-Like Receptor 7 - genetics | Interferon-alpha - metabolism | Oligodeoxyribonucleotides - immunology | Toll-Like Receptor 7 - metabolism | NF-kappa B p50 Subunit - metabolism | HIV Infections - virology | Vascular Endothelial Growth Factor Receptor-2 - metabolism | Mice, Transgenic | Nucleic Acids - metabolism | MicroRNAs - immunology | Reverse Transcriptase Polymerase Chain Reaction | Interferon-alpha - immunology | Mice, Knockout | Immunity, Innate - immunology | Animals | Interferon-alpha - blood | Mice | MicroRNAs - genetics | Nucleic Acids - immunology | Toll-Like Receptor 9 - metabolism | Host-parasite relationships | Physiological research | MicroRNA | Immune response | Research | Identification and classification
Journal Article
Nature Protocols, ISSN 1754-2189, 11/2016, Volume 11, Issue 11, pp. 2223 - 2232
Journal Article
NATURE METHODS, ISSN 1548-7091, 08/2012, Volume 9, Issue 8, pp. 840 - 840
We introduce two large-scale resources for functional analysis of microRNA (miRNA): a decoy library for inhibiting miRNA function and a sensor library for... 
NONCODING RNA | LONG-TERM | HEPATITIS-C VIRUS | RNAI ENZYME COMPLEX | TRANSGENE EXPRESSION | BIOCHEMICAL RESEARCH METHODS | DIFFERENTIATION | ENDOGENOUS MICRORNA | MAMMALIAN-CELLS | LENTIVIRAL VECTORS | ABUNDANCE | Genetic research | Usage | MicroRNA | Sensors | Properties | Methods
Journal Article
Cell Stem Cell, ISSN 1934-5909, 11/2017, Volume 21, Issue 5, pp. 564 - 565
Our understanding of early human development is typically based on inference from animal models, which may not fully recapitulate human embryonic features. As... 
OCT4 | SELF-ORGANIZATION | ZYGOTES | CELL & TISSUE ENGINEERING | CELL BIOLOGY
Journal Article
Developmental Cell, ISSN 1534-5807, 11/2016, Volume 39, Issue 3, pp. 302 - 315