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Clinical Cancer Research, ISSN 1078-0432, 05/2010, Volume 16, Issue 10, pp. 2872 - 2880
Journal Article
Nature Genetics, ISSN 1061-4036, 02/2015, Volume 47, Issue 3, pp. 250 - 256
Resistance to RAF-and MEK-targeted therapy is a major clinical challenge(1-4). RAF and MEK inhibitors are initially but only transiently effective in some but... 
COLON-CANCER | SURVIVAL | LUNG | ACTIVATION | INHIBITION | MELANOMA | SIGNALING PATHWAY | TRANSCRIPTION | GENETICS & HEREDITY | BRAF | KRAS | Humans | Molecular Targeted Therapy | Phosphoproteins - metabolism | Gene Knockdown Techniques | Heterografts | MAP Kinase Signaling System - genetics | HEK293 Cells | Female | MAP Kinase Kinase Kinases - antagonists & inhibitors | Protein-Serine-Threonine Kinases - metabolism | Proto-Oncogene Proteins B-raf - metabolism | MAP Kinase Kinase Kinases - genetics | Protein-Serine-Threonine Kinases - genetics | MAP Kinase Kinase Kinases - metabolism | Phosphoproteins - genetics | Mice, SCID | HT29 Cells | Proto-Oncogene Proteins B-raf - antagonists & inhibitors | Drug Resistance, Neoplasm - genetics | Animals | MAP Kinase Signaling System - drug effects | Proto-Oncogene Proteins B-raf - genetics | Adaptor Proteins, Signal Transducing - genetics | Cell Line, Tumor | Mice, Inbred NOD | Biomarkers, Tumor - genetics | Mice | Protein Kinase Inhibitors - pharmacology | Mutation | Adaptor Proteins, Signal Transducing - metabolism | Genes, ras | Antimitotic agents | Gene mutations | Genetic aspects | Research | Antineoplastic agents | Drug resistance | Health aspects | Thyroid cancer | Lung cancer | Colorectal cancer | Melanoma | Kinases | Charitable foundations | Cancer therapies | Design of experiments | Tumors | Index Medicus
Journal Article
JOURNAL OF CLINICAL ONCOLOGY, ISSN 0732-183X, 05/2018, Volume 36, Issue 15, pp. 9101 - 9101
Conference Proceeding
JOURNAL OF CLINICAL ONCOLOGY, ISSN 0732-183X, 05/2018, Volume 36, Issue 15, pp. e21028 - e21028
Conference Proceeding
by Ortiz, Héctor and Codina, Antonio and Monpean, Juan Luján and Doménico Fracalvieri, Fracalvieri and Biondo, Sebastiano and Rubio, Pedro Armendáriz and de Miguel Velasco, Mario and Espí Macías, Alejandro and Cazador, Antonio Codina and Ruiz Carmona, María D and Basany, Eloy Espin and Giménez, Rosana Palasí and Calvo, Alberto Parajo and Ausàs, Ignasi Camps and Pascual, Marta Piñol and Franco, Enrique Pellicer and Pascual, Vicent Viciano and Alonso, Evelio Alonso and Román, Miguel Pera and Martínez, Teresa García and Núñez, Enrique Casal and García, Jacinto García and Martín, Marcos Rodríguez and Duarte, ángel Reina and Vila, José Roig and Alustiza, José Errasti and Múgica Martirena, José Andrés and Barbadillo, José Gómez and José Antonio Toval Mata, Antonio Toval Mata and López, Manuel Ruiz and Velasco, Santiago Mera and Morgades, Ricardo Rada and Orozco, Mónica Orelogio and Quintana, Natalia Uribe and Franco Osorio, Juan De Dios and Sebastián, Antonio Arroyo and Sierra Grañón, José Enrique and Casanovas, Pilar Hernández and Cotoré, Jesús Paredes and Gallego, Gabriel Martínez and Escobar, Fernando Jiménez and Villareal, Guillermo Carreño and Té bar, Jesús Cifuentes and Abad, José Monzón and Díaz, Olga Maseda and álvarez, Daniel Huerga and Mihai, Calin Pavel and Yrayzoz, Fernando Gris and Jiménez, Inmaculada Segura and Carazo, Pablo Palma and Díaz Mejías, José Gregorio and Jiménez Redondo, José Luis and Benítez, Francisco Pérez and Porras, Vicente Portugal and Bernal Sprekelsen, Juan C and Casajuana, Fé lix Lluis and Morales, Luis Capitán and Alvarado, Nieves Cáceres and Cid, Ramón Cantero and Alegría, Javier Martínez and Estévez Diz, Alfredo and Maestre, María Victoria and Díaz Pavón, José Manuel and Pé rez, Mónica Reig and Cortijo, Antonio Amaya and Carmona Sáez, José Antonio and Miramón, Javier Jiménez and Serrat, Dídac Ribé i and Nieto, Isabel Prieto and de Francisco, Tomas González and Frade, Amor Turienzo and Sánchez, Teresa Torres and Martínez, Eva Martí and del Valle Ruiz, Sergio Rodrigo and Baños, Pedro Parra and Aceituno, Francisco Romero and Garcea, Alessandro and Solé, Ricard Batlle and García, Alberto Pérez and Ais Conde, Guillermo and de Zárate, Luis Ortiz and Pé rez, Jesús Sánchez and Estevan, Rafael Estevan and Sueiras Gil, Albert and García González, Jose María and Die Trill, Javier and Bueno, Amparo Solana and Blanco González, Francisco Javier and Lage Laredo, Ana M and Domínguez Tristancho, José Luis and Lindenbaum, Paula Dujovne
Cirugia Espanola, ISSN 0009-739X, 10/2013, Volume 91, Issue 8, pp. 496 - 503
Background: The Spanish Rectal Cancer Project of the Spanish Association of Surgeons was established in 2006. The main objective of this observational study... 
Rectal cancer | Local recurrence | Mortality | Teaching programme | Rectal cancer registry
Journal Article
Endocrinologia, diabetes y nutricion, 01/2019, Volume 66, Issue 1, p. 26
Nivolumab is an anti-cancer monoclonal antibody that inhibits PD1 and modulates T-cell response. It has been shown to significantly improve survival in several... 
Journal Article
Studies in Health Technology and Informatics, ISSN 0926-9630, 2003, Volume 94, pp. 11 - 15
Microscopes and neuronavigators are often used in neurosurgical procedures. Our Mixed Reality prototype proposes to show neuronavigator imaging overlayed onto... 
User-Computer Interface | Neurosurgery | Imaging, Three-Dimensional | Computer Simulation | Humans
Conference Proceeding
Tropical and subtropical agroecosystems, ISSN 1870-0462, 12/2011, Volume 14, Issue 3, pp. 819 - 827
En 2008, México figuraba como el segundo productor mundial (14.94%) de limones y el primero como exportador (20.5%), principalmente de limón persa, por lo que... 
Agronomy | Plant Sciences
Journal Article
Translational Lung Cancer Research, ISSN 2218-6751, 2013, Volume 2, Issue 3, pp. 244 - 250
Inhibitors targeting active protein kinases, such as EGFR or ALK, have demonstrated significant efficacy in the treatment of lung cancer. Activating mutations... 
Individualized treatment | BRAF mutations | Non-small cell lung cancer (NSCLC) | individualized treatment | Review
Journal Article
Clinical Microbiology and Infection, ISSN 1198-743X, 08/2012, Volume 18, Issue 8, pp. 786 - 794
Journal Article
Psychological Medicine, ISSN 0033-2917, 10/2018, Volume 48, Issue 13, pp. 2247 - 2256
Journal Article