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The Journal of Cell Biology, ISSN 0021-9525, 4/2004, Volume 165, Issue 1, pp. 31 - 40
Understanding gene expression control requires defining the molecular and cellular basis of mRNA turnover. We have previously shown that the human decapping... 
RNA stability | Yeasts | Messenger RNA | HEK293 cells | RNA | Lymphocytes | Plasmids | Cell lines | Cells | Cytoplasm | FRET | Cell cycle | Green fluorescent protein | Transcriptional and translational inhibitors | cell cycle | DEAD BOX HELICASE | NUCLEAR-PROTEIN | green fluorescent protein | MAMMALIAN-CELLS | SACCHAROMYCES-CEREVISIAE | ENDONUCLEOLYTIC CLEAVAGE | CELL BIOLOGY | transcriptional and translational inhibitors | DECAPPING ENZYME | NONSENSE-MEDIATED DECAY | TERMINATION CODONS | SM-LIKE PROTEINS | Endoribonucleases - genetics | Humans | Phosphoproteins - metabolism | RNA, Messenger - metabolism | Organelles - genetics | Organelles - ultrastructure | RNA Interference | Cytoplasmic Granules - metabolism | Membrane Proteins - metabolism | Protein Biosynthesis - genetics | Receptors, Chemokine - genetics | Proto-Oncogene Proteins - metabolism | Cell Line | DEAD-box RNA Helicases | Endoribonucleases - metabolism | Membrane Proteins - genetics | RNA, Messenger - genetics | Receptors, Chemokine - metabolism | Cell Compartmentation - genetics | Intracellular Signaling Peptides and Proteins | Proto-Oncogene Proteins - genetics | Phosphoproteins - genetics | RNA Nucleotidyltransferases - metabolism | RNA Stability - genetics | Proteins - genetics | Proteins - metabolism | Cytoplasmic Granules - ultrastructure | RNA Nucleotidyltransferases - genetics | Cytoplasmic Granules - genetics | Protein Biosynthesis - drug effects | Receptors, CCR4 | Organelles - metabolism | Research | Proteins | Cellular biology | Ribonucleic acid | Fluorescence | Gene expression | Ribonucleic acid--RNA | Index Medicus | cell cycle; FRET; green fluorescent protein; transcriptional and translational inhibitors; RNA stability
Journal Article
Nature Structural & Molecular Biology, ISSN 1545-9993, 01/2007, Volume 14, Issue 1, pp. 15 - 22
The conserved core of the exosome, the major eukaryotic 3' -> 5' exonuclease, contains nine subunits that form a ring similar to the phosphorolytic bacterial... 
3' END FORMATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | HUMAN PM-SCL | QUALITY-CONTROL | RIBOSOMAL-RNA | SACCHAROMYCES-CEREVISIAE | CELL BIOLOGY | BIOPHYSICS | STRUCTURAL BASIS | RIBONUCLEASE-II | POLY(A) POLYMERASE | MESSENGER-RNA DECAY | ARCHAEAL EXOSOME | Exoribonucleases - genetics | Saccharomyces cerevisiae - genetics | Exoribonucleases - chemistry | Magnesium Chloride - metabolism | Multienzyme Complexes - metabolism | RNA, Ribosomal - metabolism | RNA, Ribosomal, 5.8S - metabolism | Fungal Proteins - genetics | Saccharomyces cerevisiae Proteins - genetics | RNA Stability | RNA, Messenger - metabolism | Saccharomyces cerevisiae - chemistry | Saccharomyces cerevisiae - metabolism | Adaptor Proteins, Signal Transducing | Saccharomyces cerevisiae Proteins - metabolism | Mutation | Exosome Multienzyme Ribonuclease Complex | Exoribonucleases - metabolism | Fungal Proteins - metabolism | RNA | Yeast fungi | Physiological aspects | Genetic aspects | Research | Binding proteins | Structure | Enzymes | Genotype & phenotype | Eukaryotes | Yeast | Index Medicus | Multienzyme Complexes | Exoribonucleases | RNA, Ribosomal, 5.8S | Biochemistry, Molecular Biology | Fungal Proteins | Life Sciences | Magnesium Chloride | RNA, Ribosomal | Saccharomyces cerevisiae Proteins | Biomolecules | RNA, Messenger | Saccharomyces cerevisiae
Journal Article
Molecular Cell, ISSN 1097-2765, 11/2012, Volume 48, Issue 3, pp. 409 - 421
The exosome is a complex involved in the maturation of rRNA and sn-snoRNA, in the degradation of short-lived noncoding RNAs, and in the quality control of RNAs... 
II TRANSCRIPTS | RAPID TRANSFER-RNA | OXIDATIVE STRESS | MATURE TRANSFER-RNA | BIOCHEMISTRY & MOLECULAR BIOLOGY | POLY(A) POLYMERASE | QUALITY-CONTROL | RIBOSOMAL-RNA | SACCHAROMYCES-CEREVISIAE | BIDIRECTIONAL PROMOTERS | NUCLEAR EXOSOME | CELL BIOLOGY | Introns - genetics | Oligonucleotide Array Sequence Analysis | RNA Processing, Post-Transcriptional | RNA, Transfer - metabolism | Saccharomyces cerevisiae - genetics | RNA, Ribosomal - metabolism | Substrate Specificity | RNA Precursors - genetics | Gene Expression Profiling | Saccharomyces cerevisiae Proteins - genetics | RNA, Ribosomal - genetics | RNA, Small Nucleolar - genetics | RNA, Fungal - metabolism | Saccharomyces cerevisiae - metabolism | Blotting, Northern | RNA, Small Nucleolar - metabolism | Saccharomyces cerevisiae Proteins - metabolism | RNA, Transfer - genetics | Exosome Multienzyme Ribonuclease Complex - metabolism | RNA Precursors - metabolism | RNA, Fungal - genetics | Mutation | Exosome Multienzyme Ribonuclease Complex - genetics | Analysis | Transfer RNA | Index Medicus | RNA Precursors | Introns | Quantitative Methods | Biochemistry, Molecular Biology | Genomics | Cellular Biology | RNA, Transfer | Bacteriology | Life Sciences | Microbiology and Parasitology | RNA, Ribosomal | RNA, Small Nucleolar | Saccharomyces cerevisiae Proteins | RNA, Fungal | Subcellular Processes | Exosome Multienzyme Ribonuclease Complex | Molecular biology | Saccharomyces cerevisiae
Journal Article
Molecular Cell, ISSN 1097-2765, 10/2012, Volume 48, Issue 2, pp. 207 - 218
Journal Article
EMBO reports, ISSN 1469-221X, 06/2006, Volume 7, Issue 6, pp. 605 - 610
Recent developments in purification strategies, together with mass spectrometry (MS)‐based proteomics, have identified numerous in vivo protein complexes and... 
tandem affinity purification | mass spectrometry | cap‐binding complex | scavenger decapping complex | exosome | Exosome | Mass spectrometry | Cap-binding complex | Scavenger decapping complex | Tandem affinity purification | cap-binding complex | BIOCHEMISTRY & MOLECULAR BIOLOGY | CELL BIOLOGY | MESSENGER-RNA DEGRADATION | YEAST | RING | PURIFICATION | FRAMEWORK | PROTEIN-PROTEIN INTERACTIONS | LINK | Fungal Proteins - chemistry | Saccharomyces cerevisiae - genetics | Protein Subunits - analysis | Proteome - chemistry | Protein Subunits - metabolism | Saccharomyces cerevisiae - metabolism | Multiprotein Complexes - metabolism | Protein Subunits - isolation & purification | Gene Deletion | Mass Spectrometry | Protein Structure, Quaternary | Isotope Labeling | Genes, Fungal | Saccharomyces cerevisiae Proteins - isolation & purification | Proteomics - methods | Fungal Proteins - isolation & purification | Dimerization | Saccharomyces cerevisiae - chemistry | Protein Interaction Mapping | Saccharomyces cerevisiae - cytology | Fungal Proteins - analysis | Multiprotein Complexes - chemistry | Chromatography, Affinity | Models, Biological | Saccharomyces cerevisiae Proteins - metabolism | Protein Binding | Protein Subunits - chemistry | Proteome - metabolism | Exoribonucleases - metabolism | Fungal Proteins - metabolism | Multiprotein Complexes - isolation & purification | Saccharomyces cerevisiae Proteins - chemistry | Proteins | Molecular biology | Spectrum analysis | Research methodology | Cells | Proteomics | Index Medicus | Protein Subunits | Exoribonucleases | Multiprotein Complexes | Biochemistry, Molecular Biology | Proteome | Fungal Proteins | Life Sciences | Saccharomyces cerevisiae Proteins | Biomolecules | Saccharomyces cerevisiae | Scientific Report
Journal Article