Articles

Search Articles

Advanced search
Help

Catalogue

Articles

Databases

X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
index medicus (60) 60
humans (55) 55
asthma (38) 38
male (38) 38
female (35) 35
child (31) 31
children (30) 30
genetic predisposition to disease (23) 23
child, preschool (22) 22
immunology (22) 22
polymorphism, single nucleotide (22) 22
allergy (21) 21
genetics (21) 21
asthma - genetics (20) 20
adolescent (19) 19
association (17) 17
genes (17) 17
abridged index medicus (16) 16
analysis (16) 16
gene expression (16) 16
disease (15) 15
dna methylation (15) 15
genomes (15) 15
case-control studies (14) 14
genotype (14) 14
infant (14) 14
methylation (14) 14
respiratory system (14) 14
risk factors (14) 14
adult (13) 13
genetic aspects (13) 13
genetics & heredity (13) 13
genome-wide association study (13) 13
medicin och hälsovetenskap (13) 13
expression (12) 12
medical and health sciences (12) 12
pediatrics (12) 12
allergies (11) 11
cpg islands (11) 11
genetic research (11) 11
medicine (11) 11
age (10) 10
birth cohort (10) 10
eczema (10) 10
multidisciplinary sciences (10) 10
population (10) 10
research (10) 10
research article (10) 10
sweden (10) 10
article (9) 9
asthma in children (9) 9
childhood asthma (9) 9
dermatitis (9) 9
epigenetics (9) 9
health aspects (9) 9
klinisk medicin (9) 9
middle aged (9) 9
proteins (9) 9
risk (9) 9
studies (9) 9
children & youth (8) 8
clinical medicine (8) 8
cohort studies (8) 8
dermatitis, atopic - genetics (8) 8
dna (8) 8
epidemiology (8) 8
genetic association studies (8) 8
allergy and immunology (7) 7
atopic dermatitis (7) 7
childhood (7) 7
mutation (7) 7
receptors, g-protein-coupled - genetics (7) 7
science (7) 7
asthma - immunology (6) 6
deoxyribonucleic acid--dna (6) 6
exposure (6) 6
genetic loci (6) 6
haplotypes (6) 6
human genetics (6) 6
hypospadias - genetics (6) 6
microsatellite repeats (6) 6
pregnancy (6) 6
aged (5) 5
alleles (5) 5
biology (5) 5
blood (5) 5
cells (5) 5
chromosome mapping (5) 5
disease progression (5) 5
environmental health (5) 5
epigenetic inheritance (5) 5
genetic linkage (5) 5
genome-wide association (5) 5
hospitals (5) 5
hypersensitivity (5) 5
linkage disequilibrium (5) 5
logistic models (5) 5
mutations (5) 5
polymorphisms (5) 5
preschool children (5) 5
more...
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


1. Full Text DNA Methylation in Newborns and Maternal Smoking in Pregnancy: Genome-wide Consortium Meta-analysis
by Joubert, Bonnie R and Felix, Janine F and Yousefi, Paul and Bakulski, Kelly M and Just, Allan C and Breton, Carrie and Reese, Sarah E and Markunas, Christina A and Richmond, Rebecca C and Xu, Cheng-Jian and Xu, Zongli and Küpers, Leanne K and Oh, Sam S and Hoyo, Cathrine and Gruzieva, Olena and Söderhäll, Cilla and Salas, Lucas A and Baïz, Nour and Zhang, Hongmei and Lepeule, Johanna and Ruiz, Carlos and Ligthart, Symen and Wang, Tianyuan and Taylor, Jack A and Duijts, Liesbeth and Sharp, Gemma C and Jankipersadsing, Soesma A and Nilsen, Roy M and Vaez, Ahmad and Fallin, M. Daniele and Hu, Donglei and Litonjua, Augusto A and Fuemmeler, Bernard F and Huen, Karen and Kere, Juha and Kull, Inger and Munthe-Kaas, Monica Cheng and Gehring, Ulrike and Bustamante, Mariona and Saurel-Coubizolles, Marie José and Quraishi, Bilal M and Ren, Jie and Tost, Jörg and Gonzalez, Juan R and Peters, Marjolein J and Håberg, Siri E and van Meurs, Joyce B and Gaunt, Tom R and Kerkhof, Marjan and Corpeleijn, Eva and Feinberg, Andrew P and Eng, Celeste and Baccarelli, Andrea A and Benjamin Neelon, Sara E and Bradman, Asa and Merid, Simon Kebede and Bergström, Anna and Herceg, Zdenko and Hernandez-Vargas, Hector and Brunekreef, Bert and Pinart, Mariona and Heude, Barbara and Ewart, Susan and Yao, Jin and Lemonnier, Nathanaël and Franco, Oscar H and Wu, Michael C and Hofman, Albert and McArdle, Wendy and Van der Vlies, Pieter and Falahi, Fahimeh and Gillman, Matthew W and Barcellos, Lisa F and Kumar, Ashish and Wickman, Magnus and Guerra, Stefano and Charles, Marie-Aline and Holloway, John and Auffray, Charles and Tiemeier, Henning W and Smith, George Davey and Postma, Dirkje and Hivert, Marie-France and Eskenazi, Brenda and Vrijheid, Martine and Arshad, Hasan and Antó, Josep M and Dehghan, Abbas and Karmaus, Wilfried and Annesi-Maesano, Isabella and Sunyer, Jordi and Ghantous, Akram and Pershagen, Göran and Holland, Nina and Murphy, Susan K and DeMeo, Dawn L and Burchard, Esteban G and Ladd-Acosta, Christine and Snieder, Harold and Nystad, Wenche and ...
The American Journal of Human Genetics, ISSN 0002-9297, 04/2016, Volume 98, Issue 4, pp. 680 - 696
Epigenetic modifications, including DNA methylation, represent a potential mechanism for environmental impacts on human disease. Maternal smoking in pregnancy... 
BREAST-CANCER | IN-UTERO | CIGARETTE-SMOKING | LYMPH-NODE METASTASIS | PRENATAL EXPOSURE | TOBACCO-SMOKING | GENETICS & HEREDITY | LUNG-FUNCTION DECLINE | NEUROPILIN-2 EXPRESSION | AUTISM SPECTRUM DISORDERS | POSTSYNAPTIC DENSITY | Smoking - adverse effects | European Continental Ancestry Group - genetics | Genetic Association Studies | Epigenesis, Genetic | Humans | Child, Preschool | Infant | Chromosome Mapping | Cleft Palate - genetics | Asthma - genetics | Pregnancy | Cleft Lip - genetics | DNA Methylation | Cleft Palate - etiology | Female | Asthma - etiology | Child | Infant, Newborn | Cleft Lip - etiology | Genome-wide association studies | Genetic aspects | Nucleotide sequencing | Methylation | Health aspects | Methods | DNA sequencing | Smoking | Newborn babies | DNA methylation | Genomes | Mothers | Meta-analysis | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
2. Full Text Differential DNA methylation in purified human blood cells: Implications for cell lineage and studies on disease susceptibility
by Reinius, Lovisa E and Acevedo, Nathalie and Joerink, Maaike and Pershagen, Göran and Dahlén, Sven-Erik and Greco, Dario and Söderhäll, Cilla and Scheynius, Annika and Kere, Juha
PLoS ONE, ISSN 1932-6203, 07/2012, Volume 7, Issue 7, pp. e41361 - e41361
Methylation of cytosines at CpG sites is a common epigenetic DNA modification that can be measured by a large number of methods, now even in a genome-wide... 
METHYLOME | EPIGENOME | WIDE ASSOCIATION | MICROARRAY | MULTIDISCIPLINARY SCIENCES | GENOME | DNA Methylation | Humans | Middle Aged | CpG Islands | Disease Susceptibility - metabolism | Adult | Male | Leukocytes - metabolism | Type 2 diabetes | Medical research | Epigenetic inheritance | Genomics | Genes | Genomes | Disease susceptibility | B cells | Blood donors | Analysis | DNA | Medicine, Experimental | Genetic research | Methylation | Flow cytometry | Disease | Disorders | Leukocytes (mononuclear) | Regulatory sequences | Blood | Immunology | Granulocytes | Lymphocytes | DNA methylation | Bioinformatics | Deoxyribonucleic acid--DNA | CpG islands | Nutrition | Blood & organ donations | DNA probes | Blood cells | Neutrophils | Environmental health | Cell lineage | Gene expression | Allergies | White blood cells | Medicine | Studies | Epigenetics | Heritability | Leukocytes (granulocytic) | Index Medicus | Deoxyribonucleic acid
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
3. Full Text MMP12, Lung Function, and COPD in High-Risk Populations
by Hunninghake, Gary M and Cho, Michael H and Tesfaigzi, Yohannes and Soto-Quiros, Manuel E and Avila, Lydiana and Lasky-Su, Jessica and Stidley, Chris and Melén, Erik and Söderhäll, Cilla and Hallberg, Jenny and Kull, Inger and Kere, Juha and Svartengren, Magnus and Pershagen, Göran and Wickman, Magnus and Lange, Christoph and Demeo, Dawn L and Hersh, Craig P and Klanderman, Barbara J and Raby, Benjamin A and Sparrow, David and Shapiro, Steven D and Silverman, Edwin K and Litonjua, Augusto A and Weiss, Scott T and Celedón, Juan C
The New England Journal of Medicine, ISSN 0028-4793, 12/2009, Volume 361, Issue 27, pp. 2599 - 2608
A variant of MMP12, encoding a matrix metallopeptidase, is associated with increased lung function in children with asthma and in adult smokers. It is also... 
MEDICINE, GENERAL & INTERNAL | OBSTRUCTIVE PULMONARY-DISEASE | POLYMORPHISMS | GENE | SMOKERS | EMPHYSEMA | GROWTH | ASSOCIATION | CHILDHOOD ASTHMA | AIR-FLOW OBSTRUCTION | DECLINE | Forced Expiratory Volume - genetics | Promoter Regions, Genetic | Genetic Predisposition to Disease | Asthma - physiopathology | Humans | Middle Aged | Male | Matrix Metalloproteinase 12 - genetics | Smoking - genetics | Pulmonary Disease, Chronic Obstructive - physiopathology | Genetic Markers | Asthma - genetics | Smoking - physiopathology | Alleles | Adult | Female | Aged | Polymorphism, Single Nucleotide | Child | Cohort Studies | Pulmonary Disease, Chronic Obstructive - genetics | Medical research | Disease management | Emphysema | Risk factors | Index Medicus | Abridged Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
4. Full Text Epigenome-Wide Meta-Analysis of Methylation in Children Related to Prenatal NO2 Air Pollution Exposure
by Gruzieva, Olena and Xu, Cheng-Jian and Breton, Carrie V and Annesi-Maesano, Isabella and Anto, Josep M and Auffray, Charles and Ballereau, Stephane and Bellander, Tom and Bousquet, Jean and Bustamante, Mariona and Charles, Marie-Aline and de Kluizenaar, Yvonne and den Dekker, Herman T and Duijts, Liesbeth and Felix, Janine F and Gehring, Ulrike and Guxens, Monica and Jaddoe, Vincent V. W and Jankipersadsing, Soesma A and Merid, Simon Kebede and Kere, Juha and Kumar, Ashish and Lemonnier, Nathanael and Lepeule, Johanna and Nystad, Wenche and Page, Christian Magnus and Panasevich, Sviatlana and Postma, Dirkje and Slama, Remy and Sunyer, Jordi and Soderhall, Cilla and Yao, Jin and London, Stephanie J and Pershagen, Goran and Koppelman, Gerard H and Melen, Erik
Environmental Health Perspectives, ISSN 0091-6765, 01/2017, Volume 125, Issue 1, pp. 104 - 110
BACKGROUND: Prenatal exposure to air pollution is considered to be associated with adverse effects on child health. This may partly be mediated by mechanisms... 
OXIDATIVE STRESS | DNA METHYLATION | POLYCYCLIC AROMATIC-HYDROCARBONS | QUANTILE NORMALIZATION | MECHANISMS | PREGNANCY | ENVIRONMENTAL SCIENCES | EPIGENETICS | PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH | TOXICOLOGY | RESPIRATORY HEALTH | MATERNAL SMOKING | ASSOCIATION | Pregnancy | Air Pollutants - analysis | Air Pollution - statistics & numerical data | Nitrogen Dioxide - analysis | DNA Methylation | Prenatal Exposure Delayed Effects - epidemiology | Humans | London | Female | Child | Maternal Exposure - statistics & numerical data | Infant, Newborn | Neonates | Oxidative stress | Defensive behavior | Genes | Genomes | Mitochondrial DNA | Blood | Mitochondria | Pollution | Cord blood | Pollution effects | DNA methylation | Children | Prenatal experience | Pollutants | Bioinformatics | Deoxyribonucleic acid--DNA | Age | Indoor air quality | CpG islands | Olefinic thermoplastic elastomers | Blood cells | Exposure | Inflammation | Gene expression | Asthma | Meta-analysis | Studies | Offspring | Side effects | Epigenetics | Air pollution | Methylation | Nitrogen dioxide | Index Medicus | Contaminació de l'aire | Anomalies congènites | Embaràs | Research
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
5. Full Text Transcriptome analysis of controlled and therapy-resistant childhood asthma reveals distinct gene expression profiles
by Persson, Helena, PhD and Kwon, Andrew T., PhD and Ramilowski, Jordan A., PhD and Silberberg, Gilad, PhD and Söderhäll, Cilla, PhD and Orsmark-Pietras, Christina, PhD and Nordlund, Björn, RN, PhD and Konradsen, Jon R., MD, PhD and de Hoon, Michiel J.L., PhD and Melén, Erik, MD, PhD and Hayashizaki, Yoshihide, MD, PhD and Hedlin, Gunilla, MD, PhD and Kere, Juha, MD, PhD and Daub, Carsten O., PhD
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2015, Volume 136, Issue 3, pp. 638 - 648
Background Children with problematic severe asthma have poor disease control despite high doses of inhaled corticosteroids and additional therapy, leading to... 
Allergy and Immunology | long noncoding RNA | peripheral blood leukocytes | childhood asthma | Therapy-resistant asthma | transcriptome | CELLS | PROBLEMATIC SEVERE ASTHMA | DIFFERENTIAL EXPRESSION | LOCI | IMMUNOLOGY | CHILDREN | ALLERGY | SETS | GENOME-WIDE ASSOCIATION | Severity of Illness Index | Genome-Wide Association Study | Glucocorticoids - therapeutic use | Humans | RNA, Messenger - genetics | Transcriptome | Child, Preschool | Male | Gene Expression Profiling | Asthma - drug therapy | Asthma - genetics | Case-Control Studies | Drug Resistance - genetics | Adolescent | Receptors, Glucocorticoid - genetics | Female | JNK Mitogen-Activated Protein Kinases - genetics | Nuclear Receptor Subfamily 1, Group F, Member 1 - genetics | Asthma - pathology | Child | Sects | Asthma in children | Analysis | Genetic research | Children | Gene expression | Medicine, Preventive | Health aspects | Preventive health services | RNA polymerase | Asthma | Index Medicus | Abridged Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
6. Full Text Meta-analysis of genome-wide association studies identifies three new risk loci for atopic dermatitis
by Paternoster, Lavinia and Standl, Marie and Chen, Chih-Mei and Ramasamy, Adaikalavan and Bonnelykke, Klaus and Duijts, Liesbeth and Ferreira, Manuel A and Alves, Alexessander Couto and Thyssen, Jacob P and Albrecht, Eva and Baurecht, Hansjoerg and Feenstra, Bjarke and Sleiman, Patrick M. A and Hysi, Pirro and Warrington, Nicole M and Curjuric, Ivan and Myhre, Ronny and Curtin, John A and Groen-Blokhuis, Maria M and Kerkhof, Marjan and Saaf, Annika and Franke, Ane and Ellinghaus, David and Foelster-Holst, Regina and Dermitzakis, Emmanouil and Montgomery, Stephen B and Prokisch, Holger and Heim, Katharina and Hartikainen, Anna-Liisa and Pouta, Anneli and Pekkanen, Juha and Blakemore, Alexana I. F and Buxton, Jessica L and Kaakinen, Marika and Duffy, David L and Madden, Pamela A and Heath, Anew C and Montgomery, Grant W and Thompson, Philip J and Matheson, Melanie C and Le Souef, Peter and St Pourcain, Beate and Smith, George Davey and Henderson, John and Kemp, John P and Timpson, Nicholas J and Deloukas, Panos and Ring, Susan M and Wichmann, H-Erich and Mueller-Nurasyid, Martina and Novak, Natalija and Klopp, Norman and Roiguez, Elke and McArdle, Wendy and Linneberg, Allan and Menne, Torkil and Nohr, Ellen A and Hofman, Albert and Uitterlinden, Ane G and van Duijin, Cornelia M and Rivadeneira, Fernando and de Jongste, Johan C and van der Valk, Ralf J. P and Wjst, Matthias and Jogi, Rain and Geller, Frank and Boyd, Heather A and Murray, Jeffrey C and Kim, Cecilia and Mentch, Frank and March, Michael and Mangino, Massimo and Spector, Tim D and Bataille, Veronique and Pennell, Craig E and Holt, Patrick G and Sly, Peter and Tiesler, Carla M. T and Thiering, Elisabeth and Illig, Thomas and Imboden, Medea and Nystad, Wenche and Simpson, Angela and Hottenga, Jouke-Jan and Postma, Dirkje and Koppelman, Gerard H and Smit, Henriette A and Soderhall, Cilla and Chawes, Bo and Kreiner-Moller, Eskil and Bisgaard, Hans and Melen, Erik and Boomsma, Dorret I and Custovic, Adnan and Jacobsson, Bo and Probst-Hensch, Nicole M and Palmer, Lyle J and Glass, Daniel and Hakonarson, Hakon and Melbye, Mads and ... and Australian Asthma Genetics Consort and EArly Genetics Lifecourse Epidemio and Genetics Overweight Young Adults G and Genetics of Overweight Young Adults (GOYA) Consortium and Australian Asthma Genetics Consortium (AAGC) and EArly Genetics & Lifecourse Epidemiology (EAGLE) Consortium and The Genetics of Overweight Young Adults (GOYA) Consortium and the EArly Genetics & Lifecourse Epidemiology (EAGLE) Consortium and Sahlgrenska akademin and Göteborgs universitet and Gothenburg University and Institute of Clinical Sciences, Section for the Health of Women and Children, Department of Obstetrics and Gynecology and Sahlgrenska Academy and Institutionen för kliniska vetenskaper, sektionen för kvinnors och barns hälsa, Avdelningen för obstetrik och gynekologi
Nature Genetics, ISSN 1061-4036, 02/2012, Volume 44, Issue 2, pp. 187 - 192
Atopic dermatitis (AD) is a commonly occurring chronic skin disease with high heritability. Apart from filaggrin (FLG), the genes influencing atopic dermatitis... 
SPERMATOGENESIS | CELLULAR MOTILITY | VARIANTS | FILAGGRIN | DISEASE | GENETICS & HEREDITY | ASTHMA | MECHANISMS | DIFFERENTIATION | EXPRESSION | PSORIASIS | Dermatitis, Atopic - genetics | Genetic Predisposition to Disease | Genome-Wide Association Study | Humans | Male | Risk | Chromosomes, Human, Pair 11 - genetics | Genetic Loci | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Chromosomes, Human, Pair 5 | Cell Differentiation - genetics | Epidermis - immunology | Dermatitis, Atopic - immunology | Intermediate Filament Proteins - genetics | Kinesin - genetics | Female | Polymorphism, Single Nucleotide | Cytokines - genetics | Chromosomes, Human, Pair 20 - genetics | Quantitative trait loci | Reports | Genetic aspects | Genetic susceptibility | Atopic dermatitis | Risk factors | Confidence intervals | Genomes | Mutation | Dermatitis | Allergies | Asthma | Meta-analysis | Index Medicus | Klinisk medicin | Clinical Medicine
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
7. Full Text DNA methylation loci associated with atopy and high serum IgE: A genome-wide application of recursive Random Forest feature selection
by Everson, Todd M and Lyons, Genevieve and Zhang, Hongmei and Soto-Ramírez, Nelís and Lockett, Gabrielle A and Patil, Veeresh K and Merid, Simon K and Söderhäll, Cilla and Melén, Erik and Holloway, John W and Arshad, S. Hasan and Karmaus, Wilfried
Genome Medicine, ISSN 1756-994X, 08/2015, Volume 7, Issue 1, pp. 89 - 89
Background: The prevalence of allergic diseases are increasing worldwide, emphasizing the need to elucidate their pathogeneses. The aims of this study were to... 
ALLERGIC DISORDERS | SENSITIZATION | PREDICT | DISEASE | GENETICS & HEREDITY | ASTHMA | CLASSIFICATION | EOSINOPHIL PROTEIN-X | BIRTH COHORT | EXPRESSION | CHILDREN | Prevalence | Skin Tests | Humans | Hypersensitivity, Immediate - blood | Hypersensitivity, Immediate - genetics | Male | Genetic Loci | Immunoglobulin E - blood | DNA Methylation | Adolescent | CpG Islands | Hypersensitivity, Immediate - epidemiology | Female | Genome, Human | United Kingdom - epidemiology | Hypersensitivity, Immediate - diagnosis | Cohort Studies | Phosphates | Allergy | Epigenetic inheritance | Genes | Genomics | Immunoglobulin E | Genomes | Research | Allergic reaction | Genetic polymorphisms | Pyrimidines | DNA | Genetic research | Methylation | Biotechnology industry | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
8. Full Text IgE Sensitization in Relation to Preschool Eczema and Filaggrin Mutation
by Johansson, Emma Kristin, MD and Bergström, Anna, PhD and Kull, Inger, RN, PhD and Lind, Tomas and Söderhäll, Cilla, PhD and van Hage, Marianne, MD, PhD and Wickman, Magnus, MD, PhD and Ballardini, Natalia, MD, PhD and Wahlgren, Carl-Fredrik, MD, PhD
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2017, Volume 140, Issue 6, pp. 1572 - 1579.e5
Abstract Background Eczema (atopic dermatitis) is associated with an increased risk of having IgE antibodies. IgE sensitization may occur through an impaired... 
Allergy and Immunology | Allergens | skin barrier | birth cohort | IgE | atopic dermatitis | peanut | sensitization | filaggrin | food allergy | population | RISK-FACTORS | OF-FUNCTION MUTATIONS | IMMUNOLOGY | CHILDHOOD | CHILDREN | ATOPIC-DERMATITIS | ALLERGY | DISEASE | ASTHMA | LONGITUDINAL BIRTH COHORT | PEANUT ALLERGY | Food allergy | Atopic dermatitis | Analysis | Eczema | Immunoglobulin E | Genetic aspects | Skin | Epidemiology | Food allergies | Immunoglobulins | Disease | Antibodies | Systematic review | Filaggrin | Dermatitis | Asthma | Population | Skin diseases | Mutation | Children | Food hypersensitivity | Age | Index Medicus | Abridged Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
9. Full Text The chitinase-like protein YKL-40: A possible biomarker of inflammation and airway remodeling in severe pediatric asthma
by Konradsen, Jon R., MD, PhD and James, Anna, PhD and Nordlund, Björn, RN and Reinius, Lovisa E., PhD and Söderhäll, Cilla, PhD and Melén, Erik, MD, PhD and Wheelock, Åsa, PhD and Lödrup Carlsen, Karin C., MD, PhD and Lidegran, Marika, MD, PhD and Verhoek, Marri and Boot, Rolf G., PhD and Dahlén, Barbro, MD, PhD and Dahlén, Sven Erik, MD, PhD and Hedlin, Gunilla, MD, PhD
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2013, Volume 132, Issue 2, pp. 328 - 335.e5
Background Problematic severe childhood asthma includes a subgroup of patients who are resistant to therapy. The specific mechanisms involved are unknown, and... 
Allergy and Immunology | children | inflammation | genes | airway remodeling | imaging | Asthma | chitinases | SEVERE CHILDHOOD ASTHMA | LUNG | PROBLEMATIC SEVERE ASTHMA | IMMUNOLOGY | ALLERGY | CHI3L1 | CHITOTRIOSIDASE | Severity of Illness Index | Asthma - physiopathology | Cross-Sectional Studies | Growth Substances - blood | Humans | Lung - chemistry | Male | Biomarkers - blood | Nitric Oxide - analysis | Case-Control Studies | Adipokines - blood | Chitinase-3-Like Protein 1 | Inflammation - metabolism | Lectins - blood | Adipokines - genetics | Asthma - blood | Adolescent | Female | Lectins - genetics | Surveys and Questionnaires | Lung - metabolism | Exhalation | Airway Remodeling - physiology | Child | Pediatrics | Medical colleges | Children | Asthma in children | Health aspects | Chitinase | Body mass index | Nitric oxide | Families & family life | Biomarkers | Stress | Age | Index Medicus | Abridged Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
10. Full Text Multi-ancestry genome-wide association study of 21,000 cases and 95,000 controls identifies new risk loci for atopic dermatitis
by Paternoster, Lavinia and Standl, Marie and Waage, Johannes and Baurecht, Hansjoerg and Hotze, Melanie and Strachan, David P and Curtin, John A and Bonnelykke, Klaus and Tian, Chao and Takahashi, Atsushi and Esparza-Gordillo, Jorge and Alves, Alexessander Couto and Thyssen, Jacob P and den Dekker, Herman T and Ferreira, Manuel A and Altmaier, Elisabeth and Sleiman, Patrick M. A and Xiao, Feng Li and Gonzalez, Juan R and Marenholz, Ingo and Kalb, Birgit and Pino-Yanes, Maria and Xu, Chengjian and Carstensen, Lisbeth and Groen-Blokhuis, Maria M and Venturini, Cristina and Pennell, Craig E and Barton, Sheila J and Levin, Albert M and Curjuric, Ivan and Bustamante, Mariona and Kreiner-Moller, Eskil and Lockett, Gabrielle A and Bacelis, Jonas and Bunyavanich, Supinda and Myers, Rachel A and Matanovic, Anja and Kumar, Ashish and Tung, Joyce Y and Hirota, Tomomitsu and Kubo, Michiaki and McArdle, Wendy L and Henderson, A. John and Kemp, John P and Zheng, Jie and Smith, George Davey and Rueschendorf, Franz and Bauerfeind, Anja and Lee-Kirsch, Min Ae and Arnold, Aneas and Homuth, Georg and Schmidt, Carsten O and Mangold, Elisabeth and Cichon, Sven and Keil, Thomas and Roiguez, Elke and Peters, Annette and Franke, Ane and Lieb, Wolfgang and Novak, Natalija and Foelster-Holst, Regina and Horikoshi, Momoko and Pekkanen, Juha and Sebert, Sylvain and Husemoen, Lise L and Grarup, Niels and De Jongste, Johan C and Rivadeneira, Fernando and Hofman, Albert and Jaddoe, Vincent W. V and Pasmans, Suzanne G. M. A and Elbert, Niels J and Uitterlinden, Ane G and Marks, Guy B and Thompson, Philip J and Matheson, Melanie C and Robertson, Colin F and Ried, Janina S and Li, Jin and Zuo, Xian Bo and Zheng, Xiao Dong and Yin, Xian Yong and Sun, Liang Dan and McAleer, Maeve A and O'Regan, Grainne M and Fahy, Caoimhe M. R and Campbell, Linda E and Macek, Milan and Kurek, Michael and Hu, Donglei and Eng, Celeste and Postma, Dirkje S and Feenstra, Bjarke and Geller, Frank and Hottenga, Jouke Jan and Middeldorp, Christel M and Hysi, Pirro and Bataille, Veronique and Spector, Tim and Tiesler, Carla M. T and ... and AAGC and EArly Genetics Lifecourse Epidemio and Australian Asthma Genetics Consortium (AAGC) and the EArly Genetics and Lifecourse Epidemiology (EAGLE) Eczema Consortium and Sahlgrenska akademin and Göteborgs universitet and Gothenburg University and Institute of Clinical Sciences, Section for the Health of Women and Children, Department of Obstetrics and Gynecology and Sahlgrenska Academy and Institutionen för kliniska vetenskaper, sektionen för kvinnors och barns hälsa, Avdelningen för obstetrik och gynekologi
Nature Genetics, ISSN 1061-4036, 12/2015, Volume 47, Issue 12, pp. 1449 - +
Genetic association studies have identified 21 loci associated with atopic dermatitis risk predominantly in populations of European ancestry. To identify... 
CELLS | METAANALYSIS | VARIANTS | FILAGGRIN | DISEASE | GENETICS & HEREDITY | SUSCEPTIBILITY LOCI | ASTHMA | SKIN | INTERLEUKIN-7 RECEPTOR | IL-7 | Dermatitis, Atopic - genetics | Genetic Predisposition to Disease | Genome-Wide Association Study | Humans | Risk Factors | Immunity, Innate - genetics | Dermatitis, Atopic - pathology | Genetic Loci | Dermatitis, Atopic - ethnology | Case-Control Studies | Ethnic Groups - genetics | T-Lymphocytes - cytology | T-Lymphocytes - metabolism | Genetic Markers - genetics | Polymorphism, Single Nucleotide - genetics | T-Lymphocytes - immunology | Genome-wide association studies | Immune response | Atopic dermatitis | Development and progression | Genotype | Genetic aspects | Identification and classification | Health aspects | Methods | Studies | Confidence intervals | Inflammatory bowel disease | Genealogy | Disease | Psoriasis | Bias | Eczema | Genomes | Mutation | Dermatitis | Quality of life | Index Medicus | Genètica | Grups ètnics | Dermatitis atòpica | GENETIC ARCHITECTURE | ATES OF AMERICA | Genetics & Heredity | PE1761 | Obstetrics, Gynecology and Reproductive Medicine | INFLAMMATORY-BOWEL-DISEASE | JAPANESE POPULATION | Reproduktionsmedicin och gynekologi | V110 | PSORIASIS
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights