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Molecular systems biology, ISSN 1744-4292, 2017, Volume 13, Issue 3, pp. 916 - n/a
To elucidate the molecular mechanisms underlying non-alcoholic fatty liver disease (NAFLD), we recruited 86 subjects with varying degrees of hepatic steatosis... 
serine | NAFLD | personalized genome‐scale metabolic modeling | glutathione | personalized genome-scale metabolic modeling | FATTY LIVER-DISEASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | MUSCLE | DRUG TARGETS | CANCER | AMINO-ACID-METABOLISM | HEPATOCELLULAR-CARCINOMA | INSULIN-RESISTANCE | ADIPOSE-TISSUE | GENOME-SCALE | REVEALS | Glycine - blood | Liver - enzymology | Non-alcoholic Fatty Liver Disease - genetics | Glutathione - metabolism | Serine - blood | Humans | Liver - metabolism | Middle Aged | Male | Non-alcoholic Fatty Liver Disease - metabolism | Patient-Specific Modeling | Metabolomics - methods | Gene Expression Regulation, Enzymologic | Serine - administration & dosage | Animals | Lipoproteins - metabolism | Female | Mice | Non-alcoholic Fatty Liver Disease - diet therapy | Genome | NAD - metabolism | Serine - therapeutic use | Disease Models, Animal | Genomes | Metabolites | Metabolism | Liver | Rodents | Serine | Lipids | Biosynthesis | Glycine | Body mass index | Fatty liver | Precursors | Supplementation | Glutathione | Level (quantity) | Liver diseases | Fasting | Demand analysis | Dietary supplements | Triglycerides | Fluxes | Apolipoproteins | Gene expression | Cholesterol | Steatosis | NAD | Molecular modelling | Insulin resistance | Plasma levels | Laboratory animals | Life Sciences | Biochemistry, Molecular Biology | Biological Sciences | Naturvetenskap | Biologiska vetenskaper | Natural Sciences
Journal Article
Diabetes, Obesity and Metabolism, ISSN 1462-8902, 01/2019, Volume 21, Issue 1, pp. 84 - 94
Aims Patients with type 2 diabetes and non‐alcoholic fatty liver disease (NAFLD) exhibit considerable residual risk for cardiovascular disease (CVD). There is,... 
liraglutide | liver fat | postprandial lipids | de novo lipogenesis | apolipoprotein C3 | remnant lipoproteins | atherogenic dyslipidaemia | GLP‐1‐agonist | GLP-1-agonist | TRIGLYCERIDE | METFORMIN | PLACEBO | PARTICLES | FATTY LIVER-DISEASE | RECEPTOR AGONISTS | EXENATIDE | REMNANT CHOLESTEROL | VILDAGLIPTIN THERAPY | ENDOCRINOLOGY & METABOLISM | LIPOPROTEINS | Glycated Hemoglobin A - analysis | Hypoglycemic Agents - therapeutic use | Humans | Liver - metabolism | Middle Aged | Risk Factors | Body Weight - drug effects | Male | Hypoglycemic Agents - pharmacology | Liver - drug effects | Liraglutide - pharmacology | Weight Loss | Liraglutide - therapeutic use | Lipid Metabolism - drug effects | Postprandial Period | Female | Aged | Diabetes Mellitus, Type 2 - drug therapy | Type 2 diabetes | Medical research | Liver | Glycosylated hemoglobin | Physiological aspects | Medicine, Experimental | Triglycerides | Blood lipids | Apolipoproteins | Risk factors | Diabetes therapy | Fat metabolism | Liver diseases | Glucagon | Diabetes mellitus | Lipids | Chylomicrons | Metabolism | Insulin | Patients | Lipoproteins (very low density) | Cholesterol | Fatty liver | Apolipoprotein C-III | Oxidation | Diabetes | Lipid metabolism | Lipogenesis | Cardiovascular diseases | Diabetes mellitus (non-insulin dependent) | Original | triglyceride | liver | remnant cholesterol | metformin | fatty liver-disease | vildagliptin therapy | receptor | agonists | Endokrinologi och diabetes | particles | lipoproteins | placebo | Endocrinology and Diabetes | exenatide
Journal Article
Diabetes, Obesity and Metabolism, ISSN 1462-8902, 08/2019, Volume 21, Issue 8, pp. 1861 - 1870
Journal Article
Cell Metabolism, ISSN 1550-4131, 03/2018, Volume 27, Issue 3, pp. 559 - 571.e5
Journal Article
PLoS Genetics, ISSN 1553-7390, 05/2016, Volume 12, Issue 5, p. e1006078
Journal Article
Journal Article
Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN 1079-5642, 09/2011, Volume 31, Issue 9, pp. 2144 - 2150
Journal Article
Transplant Infectious Disease, ISSN 1398-2273, 06/2018, Volume 20, Issue 3, pp. e12868 - n/a
Journal Article
by Tabassum, R and Ramo, JT and Ripatti, P and Koskela, JT and Kurki, M and Karjalainen, J and Palta, P and Hassan, S and Nunez-Fontarnau, J and Kiiskinen, TTJ and Soderlund, S and Matikainen, N and Gerl, MJ and Surma, MA and Klose, C and Stitziel, NO and Laivuori, H and Havulinna, AS and Service, SK and Salomaa, V and Pirinen, M and Jauhiainen, M and Daly, MJ and Freimer, NB and Palotie, A and Taskinen, MR and Simons, K and Ripatti, S and Jalanko, A and Kaprio, J and Donner, K and Kaunisto, M and Mars, N and Dada, A and Shcherban, A and Ganna, A and Lehisto, A and Kilpelainen, E and Brein, G and Awaisa, G and Harju, J and Parr, K and Parolo, PD and Kajanne, R and Lemmela, S and Sipila, TP and Sipila, T and Lyhs, U and Llorens, V and Niiranen, T and Kristiansson, K and Mannikko, L and Jimenez, MG and Perola, M and Wong, R and Kilpi, T and Hiekkalinna, T and Jarvensivu, E and Kaiharju, E and Mattsson, H and Laukkanen, M and Laiho, P and Lahteenmaki, S and Sistonen, T and Soini, S and Ziemann, A and Lehtonen, A and Lertratanakul, A and Georgantas, B and Riley-Gillis, B and Quarless, D and Rahimov, F and Heap, G and Jacob, H and Waring, J and Davis, JW and Smaoui, N and Popovic, R and Esmaeeli, S and Matakidou, A and Challis, B and Close, D and Petrovski, S and Karlsson, A and Schleutker, J and Pulkki, K and Virolainen, P and Kallio, L and Mannermaa, A and Heikkinen, S and Kosma, VM and Chen, CY and Runz, H and Liu, J and Bronson, P and John, S and Landenpera, S and Eaton, S and Zhou, W and Hendolin, M and ... and FinnGen Project
NATURE COMMUNICATIONS, ISSN 2041-1723, 09/2019, Volume 10, Issue 1, pp. 1 - 14
Understanding genetic architecture of plasma lipidome could provide better insights into lipid metabolism and its link to cardiovascular diseases (CVDs). Here,... 
INSULIN | PREDIMED TRIAL | HOSPITAL DISCHARGE REGISTER | RISK-FACTORS | RARE VARIANTS | GENOTYPE IMPUTATION | CERAMIDES | MULTIDISCIPLINARY SCIENCES | DEATH | VALIDITY | GENOME-WIDE ASSOCIATION | Phenotypes | Architecture | Lipids | Genomes | Lipoprotein lipase | Triglycerides | Lipase | Gene expression | Metabolism | Fatty acids | Loci | Blood plasma | Genetic variance | Heritability | Lipid metabolism | Cardiovascular diseases | Species
Journal Article
NMR in Biomedicine, ISSN 0952-3480, 06/2010, Volume 23, Issue 5, pp. 466 - 472
The aim of this study was to investigate the use of 1H‐MRS with various echo times to characterize subcutaneous human adipose tissue (SAT) triglyceride... 
diallylic | adipose tissue | fatty acid | omega‐3 | 1H‐MRS | olefinic | Diallylic | Adipose tissue | Olefinic | Omega-3 | H-MRS | Fatty acid | Young Adult | Magnetic Resonance Spectroscopy | Time Factors | Humans | Middle Aged | Adult | Adipose Tissue - chemistry | Chromatography, Gas | Fatty Acids, Unsaturated - analysis | Lipids - analysis
Journal Article